Property | Value |
Name | A study on the clinical profile of polycystic ovary syndrome in a south Indian population. |
Description | Research article:- Medicine, Krithika D Muralidhara1*, Prabha Adhikari2, Kotian MS3 & Muralidhara DV4 1MBBS, MD, (Senior Registrar), Fr Muller Medical College, Mangalore, India. 2MBBS, MD, Professor of Medicine, Kasturba Medical College, Mangalore, India. 3MSc, Asst Professor, Dept of Community Medicine, Kasturba Medical College, Mangalore, India. 4PhD, Professor of Physiology, Faculty of Medicine and Health Sciences, University Sultan Zainal Abidin, Kuala Terengganu, Malaysia.
Abstract:- Polycystic ovarian syndrome (PCOS) is considered as a multisystem endocrinopathy. The present investigation on eighty five (85) patients diagnosed with PCOS revealed that 78% of them were overweight or obese on the basis body mass index. This fact was also partly supported by higher waist circumference in a majority of them indicating central obesity. Body weight gain at puberty was reported by over 80% of the subjects and elevated blood pressure was associated with abnormal lipid profile in a large number. Overweight/obese subjects had slightly higher fasting blood sugar levels. Metabolic syndrome features were thus evident in 33% of the subjects. However, only 4% of the subjects were infertile. Clinically, almost all subjects had developed hirsuitism and 40-70% of them had Cushingoid features. Hormonal functions such as insulin, LH/FSH ratio, male hormones, particularly dehydroepiandrosterone sulfate was higher in a considerable number of patients. 40% of the patients had hypothyroid features. The findings of study thus also support the idea that PCOS may be a manifestation of metabolic syndrome as suggested by others.
Key words:- Polycystic ovary syndrome, metabolic syndrome, obesity. |
Filename | Muralidhara et al.(217-223).pdf |
Filesize | 487.35 kB |
Filetype | pdf (Mime Type: application/pdf) |
Creator | admin |
Created On: | 12/03/2012 00:00 |
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Last updated on | 12/19/2012 10:00 |
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