DocumentsDate added
Original article
Sanjay Shyam Deo*, Prafulla Govind Herode, Abhijeet Shroff,Vishal Mandlewala,Krishan Yadav
Department of Orthopaedics, Dr. D.Y. Patil Medical College and Research Centre,Sant Tukaram Nagar, Pimpri, India
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*Dr. Sanjay Shyam Deo,
Professor, Department of Orthopaedics, Dr. D.Y. Patil Medical College and Research Centre,Sant Tukaram Nagar, Pimpri, Pune 411018, India
Article citation: Deo SS, Herode PG,Shroff A, Mandlewala V, Yadav K. Study of fracture neck femur treated with cemented bipolar prosthesis vs. Austin Moore prosthesis in elderly. J Pharm Biomed Sci 2015;05(12):961–966. Available at www.jpbms.info
Abstract:
Introduction Intracapsular femoral neck fractures are common in the elderly population. Replacement arthroplasty is now the established modality of treatment in fracture of femoral neck in the elderly due to reasons like failure of internal fixation, high rate of nonunion and avascular necrosis, poor hold of implant in internal fixation due to osteoporosis, pulmonary complications and deep vein thrombosis. This is a prospective study and results are short term. Outcomes were analysed by Harris Hip scoring system and radiographs taken during follow up.Aim and Objectives To analyse the results of Hemi arthroplasty with bipolar or Austin Moore prosthesis using Harris Hip score and determine the ideal prosthesis for study group. To study the morbidity and mortality rate and associated complications with the procedure. Materials and Methods This prospective study included 60 patients who are more than 60 years of age of both sexes. Intracapsular neck femur fracture where randomly allocated. Results It showed excellent results in 93.33% of bipolar group of patients as compared to 73.33% of Austin Moore group of patients with p value 0.05 which is significant and thus bipolar group patients have significantly higher scores as compared to Austin Moore
group patients.Conclusion Results of bipolar prosthesis seems to be better compared to Austin Moore prosthesis.
KEYWORDS bipolar, Ausitn Moore prosthesis, Harris Hip score
REFERENCES
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Statement of originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Source of funding: None.
Competing interest/Conflict of interest: The author(s) have no competing interests for financial support, publication of this research, patents, and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Review article
Ajmera Deepal Haresh1,2,3, Pradeep Singh1,2,4,Jinlin Song1,2,3*1
1College of Stomatology, Chongqing Medical University, Choongqing, China
2Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, Chongqing, China
3 Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China
4Department of Oral and Maxillofacial Surgery, College of Stomatology, Chongqing Medical University, Chongqing, China
Address reprint requests to
*Jinlin Song, MD, PhD,
Vice President,College of Stomatology, Chongqing Medical University, 426, Songshibei Road, Yubei District, Chongqing, P.R. China Post: 401147
Article citation: Ajmera DH, Singh P, Song J. Soft tissue thickness determination using CBCT in diverse medical disciplines. J Pharm Biomed Sci 2015;05(12):967–972. Available at www.jpbms.info
Abstract:
Accuracy of facial soft tissue thickness has been an important step in formulating a treatment plan for various procedures in the field of oral, maxillofacial health care as well as forensic science. There are various methods to measure soft tissue thickness but accuracy of these methods is questionable till date. The aim of this article is to make people aware of the new technology i.e., cone beam computed tomography (CBCT) its role, accuracy and its reliability in measuring the thickness of the facial and oral soft tissues, which will further help in improving the treatment plan followed by better results. Therefore, we conducted online searches and with all kinds of evidence exists we have provided the readers an overview on this new imaging modality in measuring the thickness on various soft tissue landmarks. Using routine scanning protocols we found out that cone beam CT images are reliable for measuring soft tissue thickness in the orofacial region and give a good representation of the orofacial soft tissues.
KEYWORDS CBCT, 3D technique, soft tissue thickness, facial reconstruction, facial asymmetry, gingivay.
Statement of originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Sources of Support: Project supported by (1) The Program For Innovation Team Building at Institutions of WHO Education in Chongqing;(2) The Program for Innovation Team Building at Institutions of Higher Education in Chongqing in 2013; and (3) The National Clinical Key Specialty Constitution Program of China for 2013–2014.
Acknowledgements: The Affiliated Hospital of Stomatology, Chongqing Medical University.
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research, patents, and royalties through this collaborative research.
The authors Ajmera Deepal Haresh and Pradeep Singh contributed equally to this manuscript and authors Ajmera Deepal Haresh and Pradeep Singh should be considered as first joint authors. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
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Review article
Rosaiah Kanaparthy1*, Aruna Kanaparthy2,Richa Jain3
1Assistant Professor, Department of Periodontics, College of Dentistry, Jizan University, Jizan, Saudi Arabia
2Assistant Professor, Department of Operative Dentistry, College of Dentistry, Jizan University, Jizan, Saudi Arabia
3Sr. Lecturer, Department of Periodontology, Peoples Dental Academy, Bhopal Peoples University, India
Address reprint requests to
*Dr. Rosaiah Kanaparthy,
Assistant Professor, Department of Periodontics,College of Dentistry, Jizan University, Jizan, Saudi Arabia
Article citation: Kanaparthy R, Kanaparthy A, Jain R. Significance of stem cells in periodontal regeneration: an overview.J Pharm Biomed Sci 2015;05(12):954–960.
Abstract:
Stem cell refers to a clonogenic, undifferentiated cell that is capable of self-renewal and multi-lineage differentiation. They are unique and form the basis of development, growth and survival of a living organism. Stem cells are the foundation cells of every organ and tissue in the body including the periodontium. Numerous clinical techniques, including bone grafts, root surface conditioning, barrier membranes and various growth factors, have been utilised over the years in an attempt to achieve periodontal regeneration. The recent identification and isolation of stem cells from the periodontal ligament represents a significant development in the progress towards predictable periodontal regeneration. This review is an overview on the role of stem cells and tissue engineering in periodontal regeneration.
KEYWORDS Stem cell,Dental pulp stem cells,Periodontal ligament stem cells, Stem cells from apical papilla.
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Statement of originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Source of funding: None.
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research, patents, and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Clinical Case
Minira Bulegenova1*,Oleg Mustafin2, Anna Makhneva3,Aigul Bekisheva4
1 Professor, Head of Laboratory Department,Almaty, Kazakhstan
2 Head of Somatic Pathology Department,Almaty, Kazakhstan
3 Researcher, Laboratory of Pathomorphology, Almaty, Kazakhstan
4 Pathomorphologist, Laboratory of Pathomorphology, Almaty, Kazakhstan
The name of the department(s) and institution(s) to which the work should be attributed:
Laboratory Department and Somatic Pathology Department, Scientific Center of Pediatrics and Children Surgery
Address reprint requests to
*Minira Bulegenova, Professor and Head of Laboratory Department, Scientific Center of Pediatrics and Children Surgery, Kazakhstan, Almaty, Al Farabi ave.
Article citation: Bulegenova M, Mustafin O, Makhneva A, Bekisheva A. Severe form of primary intestinal lymphangiectasia in an one-year-old child. J Pharm Biomed Sci 2015;05(12):924–927. Available at www.jpbms.info
Abstract:
Primary intestinal lymphangiectasia (Waldmann syndrome) is a congenital abnormality of the lymphatic system in children–a disease that occurs infrequently. There are about
80 published descriptions of this pathology in infants. The main clinical manifestation of intestinal lymphangiectasia is a syndrome of malabsorption: diarrhoea, nausea, vomiting, abdominal pain and peripheral oedema. In some cases, steatorrhoea of varying severity occurs. Long lasting of the disease, no effect on the therapy leads to such complications as chylous ascites and chylothorax. This paper presents a clinical case of an early debut primary intestinal lymphangiectasia in a 6-month-old child, complicated by development of concomitant immunodeficiency. The final diagnosis was set after the histological examination of biopsy material in jejunum. Substitution therapy with albumin had no positive effect. Because of the constant hypoproteinemia that had not been corrected with either albumin or ongoing corticosteroid therapy, it was decided to start the sandostatin therapy. With improvement in the patient’s condition, he was transferred from intensive care to the department of somatic pathology.Transfusions of albumin have been cancelled. The protein level increased up to 53 g/l, swelling disappeared, but general sponginess of the tissue remained. The patient was discharged from the hospital with recommendations to continue the combined therapy including sandostatin and compulsory monitoring of the concentration of immunoglobulins.
KEYWORDS intestinal lymphangiectasia, malabsorption syndrome, hypoproteinemia, immunodeficiency, sandostatin
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Statement of originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Research article
Sambashivaiah Savita1,Ambica2*, Kulal Rithesh3,G. Veena2, P. Poorna P2,Vimal Kumar Varsha4
1 Professor & Head of Department,Department of Periodontology,Rajarajeswari Dental College and Hospital, Bangalore, Karnataka, India
2 Post Graduate, Department of Periodontology,Rajarajeswari Dental College and Hospital, Bangalore, Karnataka, India
3 Reader, Department of Periodontology,Rajarajeswari Dental College and Hospital, Bangalore, Karnataka, India
4 Senior Lecturer, Department of Oral Pathology and Microbiology, Rajarajeswari Dental College and Hospital, Bangalore, Karnataka, India
The name of the department(s) and institution(s) to which the work should be attributed to:
Department of Periodontology, Rajarajeswari Dental College and Hospital, Bangalore,
Karnataka, India
Address reprint requests to
*Dr. Ambica,
Post Graduate, Department of Periodontology, Rajarajeswari Dental College and Hospital, Bangalore,Karnataka 560074, India
Article citation: S Savita, Ambica, K Rithesh,GundapaneniVeenadharini, P Poorna, VK. Quantification of mast cells in periodontal diseases: a comparative study. J Pharm Biomed Sci 2015;05(12):919–923. Available at www.jpbms.info
Objective The present study was undertaken to identify and quantify the presence of mast cells in human periodontal disease using histochemical (toluidine blue [TB]) technique. Materials and Methods A total of 45 tissue samples were obtained for the study: GROUP 1, 15 cases of clinically healthy gingival tissues, GROUP 2, 15 cases of pericoronitis and GROUP 3, 15 cases of chronic periodontitis were selected. Periodontally healthy tissue samples were obtained from premolar teeth extracted for orthodontic reasons. Samples of chronic periodontitis were obtained from teeth extracted due to poor periodontal prognosis. In pericoronitis group impacted third molar and operculum with inflammatory signs were selected. Sample fixed in 10% buffered formalin and stained with TB stain and observed under binocular microscope. Result Mast cell densities (cells per mm2) were significantly increased in chronic periodontitis, and pericoronitis group compared to clinically healthy gingival tissues by histochemical technique. Conclusion In human periodontal disease there is an increase in the number of mast cells that may be contributing either in the destructive events or in the defense mechanism of periodontal disease via secretion of cytokines, cellular migration and healing processes.
KEYWORDS chronic periodontitis, pericoronitis, mast cells, toluidine blue
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Statement of originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Source of funding: None.
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research, patents, and royalties through this collaborative research. All authors were equally involved in discussed research work.
There is no financial conflict with the subject matter discussed in the manuscript.