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Original article
Rathore Praveen K1,Amritesh Kumar2,Anamika Vyas3,Rajesh Bareja4*,Amar S Dalal5
1Department of Microbiology, Jodhpur Medical College & Hospital, Boranada,Jodhpur, Rajasthan, India – 342012
2,3,5 Department of Microbiology, Geetanjali Medical College & Hospital, Udaipur,Rajasthan,India – 313001
4 Department of Microbiology, S.R.M.S.Institute of Medical Sciences, Bhojipura,Bareilly, Uttar Pradesh – 243202
Address reprint requests to
*Rajesh Bareja,
Assistant professor,Department of Microbiology, SRMS Institute of Medical Sciences, Bhojipura, Bareilly, Uttar Pradesh 243202, India
Article citation: Praveen RK, Amritesh K,Anamika V, Rajesh B. Incidence of rubella antibodies among pregnant women in a tertiary care hospital. J Pharm Biomed Sci 2016;06(02):110–114. Available at www.jpbms.info
DOI: http://dx.doi.org/10.20936/jpbms/160206
ABSTRACT
Background In itself, the disease is trivial but rubella in pregnant women may lead to congenital malformations in the baby. Aims and Objective This study was aimed to determine and analyse the prevalence of rubella antibodies among pregnant women.Materials and Methods A total of 100 pregnant women were included in this study. Out of 100 pregnant women, 38 cases were from 1st trimester, 35 from 2nd trimester and 27 cases from 3rd trimester. About 2–3 ml of blood sample was collected aseptically from pregnant women at the antenatal clinic and was processed accordingly for detection of IgG and IgM antibodies specific for rubella virus by enzyme-linked immunosorbent assay(ELISA).
Results Out of 100, 94% and 7% of pregnant women were seropositive for anti-rubella IgG and IgM antibodies, respectively. Highest seropositivity for rubella IgG was found in age group 20–25 years (97.61%) followed by 26–30 years (91.89%). Higher seropositivity for rubella IgG antibodies was observed in female residents of rural areas (94.59%) as compared to those residents of urban areas (93.65%).
Conclusion Prevention of morbidity and mortality from rubella infection depends on prevention of infection in childbearing women and early recognition of maternal infection.
KEYWORDS ELISA, IgG, IgM, pregnant women, rubella
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Statement of originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes
that the manuscript represents honest and original work.
Sources of support: None
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research,patents, and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
ORIGINAL ARTICLE
Prafulla G Herode*, Satish Uchale,Abhijeet Shroff,Vinod Nair,Amit Chaudhary
Department of Orthopaedics, Dr. D.Y. Patil Medical College, Pimpri, Pune, Maharashtra,India
ABSTRACT
Background Distal radius fractures are the most frequent fractures in the upper extremity. In adults they show a wide range of variation and are responsible for 10–20% of all skeletal fractures. The advent of fixed-angle locking plates has addressed inadequacies such as non-locked plates and has improved fracture healing. The purpose of this study was to investigate the efficacy volar locking plate in the management of the intra-articular and extra-articular volar fractures of distal end of radius of as well as to report the radiological and functional outcomes.
Aims and Objectives To study the role of locking plate in volar fractures of distal end radius.
Materials and Methods This prospective study comprised 25 patients. Fresh simple volar fracture (age >20 yrs) of lower end of radius presenting within a week of injury, who were treated with volar locking plate fixation at tertiary care teaching hospital was carried out from April 2012 to November 2014. Patients were evaluated for Stewart I radiological scoring system and Functional Patient Rated Wrist Evaluation (PRWE) scoring system. The radiological and functional outcomes were measured and analysed using the ANOVA chi square test.
Results According to Stewart score, in this study, 22 (88%) cases showed satisfactory anatomical results (good and excellent) hence volar fractures of distal radius is associated with satisfactory anatomical end result. Patient rated wrist evaluation scoring showed 22 patients with satisfactory functional results (good and excellent) considering pain and functional activities and 3 patients with unsatisfactory results (fair and poor).
Conclusion Open reduction and internal fixation with volar Locking plating has excellent functional outcome with minimal complications thus proving that it is a good modality of treatment for distal end radius fractures.
Address reprint requests to
*Dr. Prafulla Govind Herode,
Associate Professor, Department of Orthopaedics, Dr. D.Y. Patil Medical College, Hospital and Research centre, Pimpri, Pune 411108, India
Article citation: Herode PG, Uchale S,Shroff A, Nair V, Chaudhary A. Prospective study of distal end radius fracture volar type treated with open reduction internal fixation with plating. J Pharm Biomed Sci 2016;06(02):134–138.Available at www.jpbms.info
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8.MacDermid JC, Richards RS, Donner A, Bellamy N, Roth JH.Responsiveness of the short form-36, disability of the arm, shoulder, and hand questionnaire, patient-rated wrist evaluation, and physical impairment measurements in evaluating recovery after a distal radius fracture. J Hand Surg Am. 2000;25:330–40.
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16.Stewart HD, Innes AR, Burke FD. Functional cast bracing for Colles’ fracture. A comparison between cast-bracing and conventional plaster casts. J Bone Joint Surg Br. 1984;66:749–753.
Statement of originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Sources of funding: None.
Competing interest / Conflict of interest:
The author(s) have no competing interests for financial support, publication of this research,
patents, and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the
official policy or position of the Department of Defense.
Original article
Amit Anand1*,Alin Kumar Nayak2,Nirmalya Nirbisank3
1 Third year PG student, Department of General Surgery, Hi-Tech Medical College and Hospital, Bhubaneswar, Odisha, India
2 Third year PG student, Department of General Surgery, Hi-Tech Medical College and Hospital, Bhubaneswar, Odisha, India
3 Senior resident, Department of General Surgery, Hi-Tech Medical College and Hospital, Bhubaneswar, Odisha, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of General Surgery, Hi-Tech Medical College and Hospital Bhubaneswar, Odisha, India
Address reprint requests to
*Dr Amit Anand, 3rd yr PG student, Department of General Surgery, Hi-Tech Medical College and Hospital, Bhubaneshwar, Orissa, India
Article citation: Anand A, Nayak AK,Nirbisank N. Case study on various presentation and management of acute intestinal obstruction. J Pharm Biomed Sci 2016;06(02):121–123.Available at www.jpbms.info
DOI: http://dx.doi.org/10.20936/jpbms/160208
ABSTRACT
Bowel obstruction remains one of the most common intra-abdominal problems faced by general surgeons in their practice whether caused by hernia, neoplasm, adhesions or related to biochemical disturbance. Small or large bowel continues to be a major cause of morbidity and mortality to identify and analyse the clinical presentation, management and outcome of the patients with acute intestinal obstruction. The objectives are to study the various mode of presentation, various causes, influence of various factor like age, sex, diet and socioeconomic status in the pathogenesis of intestinal obstruction, morbidity and mortality rates in acute intestinal obstruction.
Materials and Methods Clinical study of intestinal obstruction were collected from case admitted to various surgical wards in Hi-Tech Medical College and Hospitals, Bhubaneswar, Odisha, India, during the period from August 2013 to September 2015.
Results The study was conducted on 50 cases who were admitted in Hi-Tech Medical College with features of intestinal obstruction.
Conclusion In this study we assess the common causes of intestinal obstruction in different age groups and its management.
KEYWORDS acute intestinal obstruction, gastrointestinal, adhesions
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Statement of originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes
that the manuscript represents honest and original work.
Sources of support: None
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research,patents, and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Original article
Vinod Nair,Satish Uchale,Prafulla Govind Herode,Aabhijeet Shroff,Krishan Yadav*
Department of Orthopaedics, Dr. D.Y. Patil Medical College, Pimpri, Pune, Maharashtra
Address reprint requests to
*Dr. Krishan Yadav,
Department of Orthopaedics, Dr. D.Y. Patil Medical College, Pimpri, Pune, Maharashtra, India
Article citation: Nair V, Uchale S, Herode PG, Shroff A, Yadav K. Comparative study between the role of medial LCP and anterolateral LCP in the management of fractures of distal tibia. J Pharm Biomed Sci 2016;06(02):115–120. Available at www. jpbms. info
DOI: http://dx.doi.org/10.20936/jpbms/160207
ABSTRACT
Background As the civilisation proceeds towards industrialisation more and more accidents have been experienced. In almost all over the world, the incidence of road traffic and industrial accidents are growing up, resulting in fracture of various bones of body. Leg bones fracture are very common because it is the most distal part of the body and is actively involved in locomotive system. Out of all the leg bones fracture, a significant number of cases are of distal tibia which are generally comminuted in nature and are unstable. As these fractures occur in proximity of weight bearing surface of ankle joint, a slight maladjustment in inclination of ankle joint may lead to permanent disability. Besides closed reduction with casting many osteosynthesis techniques can be used for these fracture such open reduction and internal fixation with locking plate, external fixation with or without limited internal fixation, intra-medullary nailing. Two types of LCP can be used in the management of fractures of distal one third of tibia i.e. medial LCP and the newer anterolateral LCP.
Aims and Objectives To study the management of fractures of distal tibia using medial LCP and anterolateral LCP and to assess and compare the end results of above procedure in terms of benefits and complications.
Materials and Methods This is a prospective randomised study from December 2013 to December 2015 for management of distal tibia fractures treated by medial LCP and Anterolateral LCP.
Results Study was performed on 50 patients out of which 25 were treated by medial LCP and 25 by anterolateral LCP. In study it was seen that medial and anterolateral plating duration of surgery, time of appearance of callus, and time for full weight bearing of patient were almost same but infection rate and hardware problem was lower in anterolateral plating.
Conclusion The objective is to obtain anatomic realignment of the joint surface while providing enough stability to allow early motion. This should be accomplished using techniques that minimise osseous and soft tissue devascularisation in the hopes of decreasing the complications resulting from treatment.
KEYWORDS distal tibia fractures, internal fixation, open reduction, Laughansen, mortise view, anatomical reduction
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Statement of originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Sources of support: None
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research,patents, and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Review article
Bharati Kolliyavar1*,Leena Shettar2,Srinath Thakur3
1* Assistant Professor, Department of Periodontics & Oral Implantology, SDM College of Dental Sciences & Hospital,Sattur, Dharwad, Karnataka, India
2 Professor and Head of Department of Periodontics, SDM College of Dental Sciences & Hospital, Sattur, Dharwad,Karnataka, India
3 Professor and Principal, SDM College of Dental Sciences & Hospital, Sattur,Dharwad, Karnataka, India
Address reprint requests to
*Dr. Bharati Kolliyavar, Assistant Professor, Department of Periodontics & Oral Implantology, SDM College of Dental Sciences & Hospital, Sattur, Dharwad, Karnataka, India
Article citation: Kolliyavar B, Shettar L,Thakur S. Chlorhexidine: the gold standard mouth wash. J Pharm Biomed Sci 2016;06(02):106–109.Available at www.jpbms.info
DOI: http://dx.doi.org/10.20936/jpbms/160205
ABSTRACT
Chlorhexidine (CHX) is used as the broad spectrum antiseptic since 1950. It is a widely used mouth wash because of its antiplaque and antigingivitis properties. Antibacterial activity of CHX is mainly by disrupting bacterial cell membrane, which causes leakage of cellular constituents and brings about cell death. Bactericidal and bacteriostatic activity depends on the dosage. This article discusses various clinical applications, properties and adverse effects of CHX.
KEYWORDS chlorhexidine, mouth wash, antiplaque agent
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