DocumentsDate added
Research article:-
* SULE, O.J,1 ELEKWA, I.2 and JOFFA, P.P.K3.
1Department of Medical Biochemistry, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria.
2Department of Biochemistry, Abia State University, Uturu, Abia State, Nigeria.
3Department of Physiology, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria.
Abstract:- The role of C. papaya for the prevention of CCl4 induced liver damage was investigated. Thirty wistar albino rats were allotted to six groups. Rats in group1 were fed with 100% feed and administered CCl4, while those in groups (2, 3 and 4) were pretreated with 10%, 30%, and 50% of dried leaves of C. papaya respectively. Rats in groups 5 and 6 received 30% C. papaya and 100% feed without administration of CCl4 (positive and general controls respectively). CCl4 induction was carried out on the 29th day of study (0.5 ml/kg body weight in 0.5 ml olive oil intraperitoneally). Rats were starved for 24hrs, scarified on the 30th day of study and the serum was used to investigate the activities of liver marker enzymes (ALT, AST, ALP, CPK and LDH) using colorimetric methods. Morphology parameters were also assessed. Data obtained were analyzed by inferential statistics using ANOVA. There was significant increases (p ≤ 0.05) in the levels of serum enzymes ( ALT, AST, ALP, CPK and LDH) in CCl4 treated rats when compared with rats groups that were pre-treated with 10%, 30% and 50% C. papaya prior to administration of CCl4. However, there were significant decreases (p ≤ 0.05) in the levels of ALT, AST, ALP, CPK and LDH in rats that were pre-treated with 10%, 30% and 50% C. papaya when compared with the rats that were administered CCl4 only, in a dose dependent manner. Liver weights decreased significantly (p ≤ 0.05) in rats administered with CCl4 only. However, there was significant increase (p ≤ 0.05) in the liver weights of rats that were pre-treated with 10%, 30% and 50% Carica papaya, when compared with the rats that received CCl4 only. Unusual aggressive behavioral display was noticed in the pretreated experimental groups.
Key Words:- Carica papaya (C. papaya), Carbon tetrachloride (CCl4), morphology, wistar rats etc.
Article Retracted
The article has been retracted due to conflict of interest between author.
Retraction of
Fahd Manzoor Thokar et al.Extended spectrum-β-Lactamase (ESBL) producing community acquired Escherichia coli isolates & their antimicrobial susceptibility pattern in Kashmir.JPBMS;2012:15(01).
Research article:-
*R.C.Pantola1, G.S.Shekhawat2
1Research scholar, Department of Biosciences and Biotechnology, Banasthali University, Banasthali 304022, Rajasthan, India.
2Associate Professor, Department of Biosciences and Biotechnology, Banasthali University, Banasthali 304022, Rajasthan, India.
Abstract:-In vitro grown seedlings of Brassica juncea were treated with 0.5, 1.0, 5.0, 10.0, 20.0, 40.0, 50.0, 75.0, and 100.0 µ mol concentration of copper and compared with non- treated control. Antioxidative enzymes (superoxide dusmutase (SOD), ascorbate peroxidase (APX) and catalase (CAT)) indices of leaves were studied by analyzing these antioxidative enzymes in day 5 and 10. The seedlings were grown on Hoagland’s nutrient solution. Our results indicate an enhancement in the activity of APX in response to copper stress at 10 µ mol on day 5 and 1, 5,10,40,50 and 75 µ mol copper treatment on day 10. While the APX activity decreased at 1,5,20,40,50,75 and 100 µ mol on day 5 and 0.5,20,100 µ mol on day 10. CAT activity increased at 5,10,40,50 and 75 µ mol copper concentration on day 10 , at 10 and 20 µ mol on day 5,while it was moderate at 0.5,40,50,75, and 100 µ mol on day 5 and 0.5 and 1 µ mol on day 10. CAT activity was decreased on day 5 at 0.5 and 20 µ mol and 100 µ mol on day 10, with respect to untreated control. SOD activity gradually decreased up to 5 µ mol and increased at 10 µ mol but at 20, 40, 50 and 75 µ mol it was observed slightly, gradual increment, at 100 µ mol it was drastically high that is more than double of control. On day 10, SOD activity was found less than control up to 10 µ mol, at 20 µ mol it was minimal and again at 40, 50, 75 and 100 µ mol it remains somehow equal but less than control.
Key Words:- Antioxidant enzymes. Brassica juncea, Copper, Oxidative stress.
Research article:-
* S.Sudhakar1, K.Kotteeswaran1, Vaiyapuri Anandh 2, M.Santha3 .
1 Asst Professor, Saveetha College of Physiotherapy, Saveetha University, Chennai, India.
2 PG Lecturer, Saveetha College of Physiotherapy, Saveetha University, Chennai, India .
3 Principal, Saveetha College of Physiotherapy, Saveetha University, Chennai, India.
4 PG Student, Saveetha College of Physiotherapy, Saveetha University, Chennai, India.
Abstract:- Aim: The aim of the study was to analyze, the effects of slump stretching in comparison to interferential therapy in subjects with low back pain. Objective: The objective of the study was to evaluate the treatment efficacy of slump stretching for patients with low back pain in reducing pain and disability. Study Design: Experimental study design Study Setting: Outpatient Department, Saveetha college of Physiotherapy, Saveetha University, Thandalam, Chennai -602 105 Method: 60 subjects with back pain radiating to lower limb who fulfills the inclusion criteria were recruited and they were randomized to receive slum stretching with exercise or interferential therapy with exercise. All patients were treated every alternate day for 2 weeks. Outcome Measures: Numerical pain rating scale, Body diagram, Modified Oswestry disability index. Result: Using ‘t’ test in the data the result shows that there is a significant difference between Group-A and Group-B in reducing pain and disability and improving centralization of symptoms. The post test mean value of NPRS score in Group-A is 1.80 (SD 0.71) and in Group-B is 2.47 (SD 1.25). The post test mean value of body diagram score in Group-A is 1.30 (SD- 0.95) and in Group-B is 1.97 (SD 0.96).The post test mean value of Modified Oswestry Index score in Group-A is 8.93 (SD 5.63) and in Group-B is 11.73 (SD 4.86) this shows that the scores in Group-A is lesser than Group-B with the P<0.05(5% level). This shows that slump stretching group produces better relief in pain and disability and also produces better improvement in centralization of symptoms in comparison with interferential therapy group. Conclusion: The present study reveals that the treatment given to both the groups were effective in reducing pain, disability and centralization of the symptoms. However the reduction of symptoms were found to be statistically significant in group-A in which slump stretching and exercise was incorporated as compared to Group-B in which interferential therapy and exercise was used. Thus the study suggests that slump stretching can be used clinically to treat the symptoms of the patients with low back pain radiating distally to lower limb.
Key Words:- Low back pain, interferential therapy, slump stretching
Research article:-* Jamal A. Khan1 Sarwat F. Usmani 2, Samiullah Khan3
1 Department of Chemistry, Aligarh Muslim University, Aligarh ,India.
2 Department of Chemistry, NIMS, University, Jaipur, India.
3 Department of Applied Chemistry, Aligarh Muslim University, Aligarh, India.
Abstract:-The present study deals with the effect of fly ash on the mobility of amino acids through six typical soil of Aligarh district, their mobilities of amino acids in these soils showed the order Type I > type IV > Type II > Type VI > Type III > Type V, and the mobility of amino acids in all six soils followed the order Valine > alanine > glycine > lysine. The results had been explained on the basis of physical and chemical characteristics of six different types of soil and the molecular behavior of amino acids in soil medium.
Key Words:- Fly ash, amino acids, soil medium.