DocumentsDate added
Research article:-
*Eryılmaz Müjde1, Akın Ahmet2, Altanlar Nurten2
1Ph.D, 2Prof.Dr. Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Ankara University, Ankara, Turkey.
Abstract:-Antiseptics are an essential part of infection control practices and aid in the prevention of nosocomial infections. The selection of the proper antimicrobial agent is a very crucial step before application. The aim of this study was to compare the efficacy of 2% chlorhexidine gluconate (2% CHG) and 10% povidone iodine (10% PVP-I) alone and in combination with 70% 2-propanol (70% 2-P) against nosocomial methicillin-resistant Staphylococcus aureus (MRSA) and Enterococcus faecalis isolates. A total of 15 MRSA and 15 E. faecalis strains isolated from blood cultures of hospitalized patients as nosocomial infection agents in Ankara University, Faculty of Medicine, Ibn-i Sina Hospital, Ankara, Turkey were included in the study. Susceptibilities of the isolates to antiseptics were investigated by quantitative suspension test at 30 seconds contact time. All of the isolates were found susceptible to 2% CHG in 70% 2-P and 10% PVP-I in 70% 2-P. However, three MRSA and four E.faecalis isolates were found resistant to 2% CHG; three MRSA and three E.faecalis isolates were found resistant to 10% PVP-I . Our study has demonstrated that 2% CHG in 70% 2-P and 10% PVP-I in 70% 2-P provide a significantly better antimicrobial activity than 10% PVP-I and 2% CHG alone at 30 seconds contact time. According to the results, enhanced skin antisepsis may be achieved with 2% CHG in 70% 2-P or 10% PVP-I in 70% 2-P compared with the 2% CHG and 10% PVP-I alone.
Key Words:- Chlorhexidine gluconate, Povidone iodine, 2-propanol, Skin antisepsis.
Research article:-
* Chavada Nikul1, Dr Kiran K.Deshmukh2.
1 K.J. Collage of Pharmacy Vadasma-382708 Gujarat. India.
2 P.H.G. Municipal Arts and Science Collage-Kalol, Gujarat India.
Abstract:-Soil being habitat for microbial flora function as a natural vat for all kind of microorganisms. Its provide favorable environment for pathogenic and non-pathogenic microorganisms. Soil play key role of disseminating microorganisms in air and water. Present study, indicate pathogenic bacteria in soil samples, collected from the vicinity of Seafood Industries established in Veraval G.I.D.C, .Organic nutrient waste from sea food companies, supported both pathogenic and non-pathogenic bacteria. Three samples collected from different location of G.I.D.C area were microbially analyzed for pathogens. .Results indicate persistence of Salmonella Spp,. Salmonella Spp,being potent pathogen of human being ,lime lighted the soil, collected from the vicinity of sea food companies.
Key words:- Seafood, pathogenic organisms, microbial analysis.
Research article:-
* Lodhiya Kaushik K..1 , Pithadia Pradeep R.2 , Dhaduk Kishor M.3 , Yadav Sudha B.4
1 M.D. (Community Medicine), Tutor, Community Medicine Department, M. P. Shah Medical College, Jamnagar, India.
2 M.D. (Community Medicine), Tutor, Community Medicine Department, M. P. Shah Medical College, Jamnagar, India.
3 M.D. (Community Medicine), Assistant Professor, Community Medicine Department, M. P. Shah Medical College, Jamnagar, India.
4 M.D. (Community Medicine), Additional Dean and Professor and Head Community Medicine Department, M. P. Shah Medical College, Jamnagar, India.
Abstract:-Background: Health workers (HW) are the back bone of health care service delivery in India where more than three quarters of the masses lives in rural areas. Immunization is one of the key activities of HW which can reduce under five mortality rate, if practiced as per guidelines. So the study was carried out with the following objectives. Objective: To assess the knowledge and skills of HW’s. Material and method: This was a cross sectional descriptive study, conducted in rural areas of Jamnagar district. Data were obtained through on site observation for evaluation of various technical skills and Pre tested semi-structured Performa was used for assessing their knowledge and practice in context to UIP services. Statistical Analysis: Chi-square test used where appropriate. Results: The knowledge and practices of HW’s were lagging in some of the key areas of immunization. In spite of clear guidelines on non use of spirit swabs for cleaning injection sites before giving vaccines, only 66% & 63% of HW-F & HW-M used water swab respectively. Proper waste collection & disposal techniques were not followed by 48% of HW-Fs & 90% of HW-Ms. Similarly only about 55-60% of HWs used the correct technique for giving various vaccines. Conclusion: The Knowledge, practices and skills of HW’s were not of required standards with HW-M’s performing the worst.
Key Words:- Health workers, Immunization, Knowledge, Skills, Universal immunization program.
Research article:-
Dr. Singh Rachana, Agarwal Tarun*, Rastogi Rinki, Arora Neha, Rastogi Meghana.
Amity Institute of Biotechnology, Amity University, Lucknow, India.
Abstract:- The present study presents the effectiveness of Jatropha curcas Fruit against some selected microorganisms which are known to cause diseases in human beings and the comparative study of extent of antimicrobial properties of various fruit parts of Jatropha curcas namely, Fruit Pericarp, Seed Coat and Seed Kernel. Cold Aqueous, Methanolic, Ethanolic, and Ethyl Acetate extracts of dried fruit parts were prepared at a final concentration of 500 mg/ml and were tested against pathogenic microorganisms such as Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli using agar well diffusion method. The Methanolic extracts of the Seed Kernel showed the maximum zone of inhibition of 25.5mm.
Keywords:- Antibacterial properties, Jatropha curcas fruit, Fruit Pericarp, Seed Coat and Kernel, Agar Well Diffusion.
Research article:-* Amarjeet S Wagh1 and Naveen Jain2.
1 Department of Pediatrics & Neonatology , Kerala Institute of Medical Sciences, Trivandrum, Kerala, India.
2 DM, Consultant Neonatologist, Kerala Institute of Medical Sciences, Trivandrum, Kerala, India.
Abstract:- Objectives: To compare the neonatal morbidities of late preterm babies with babies born term. Methods: Prospective observational study. Settings: Referral NICU Study period: 18 months Results: 114 late preterm babies were compared against 1094 term born babies. Late preterm babies had more neonatal morbidities compared to term babies (85 % vs 16.3 %). Need for resuscitation (14 vs 1.7 %), need for respiratory support (29.8 vs 3.4 %), hypoglycemia (30 vs 2.2 %), hyperbilirubinemia (50 vs 10.4 %), sepsis (9.6 vs 0.9 %), need for intravenous fluids (58 vs 2 %) were more in late preterms as compared to term babies. 94 % term babies were exclusively breast fed at discharge as against only 53.5 % late preterms. 83 (72.8 %) babies were followed up to 3 months age corrected for prematurity. 3.6 % had weights less than 5th centile and 83 % between 5 – 50th. 4.8 % of babies had an abnormal field on DDST and 20.4 % had a questionable test. Babies delivered late preterm for maternal or fetal indications had significantly more risk of neonatal morbidities than those born early due to preterm labor. Use of antenatal steroids did not alter outcomes. Conclusions: late preterm babies have higher risk of neonatal morbidities. They are likely to have growth and development concerns even at 3 months corrected age.
Keywords:- late preterm, term, neonatal morbidities.