DocumentsDate added
Original research article:- Dental Sciences
*Rizwan M Sanadi
Reader, Dept of Periodontics, Yerala Medical Trust & Research Centre’s ,Dental College & Hospital, PG Institution, Institutional Area, Sector – 4, Kharghar, Navi Mumbai- 410210 ,Maharashtra, India.
Abstract:- Aggressive periodontitis comprises a group of rare, severe, rapidly progressing forms of periodontitis characterized by an early age of clinical manifestation and a distinctive tendency for cases to aggregate in families. Aggressive periodontitis, typically results in severe, rapid destruction of the tooth supporting apparatus. The increased susceptibility of the host population with aggressive periodontitis may be caused by the combined effects of multiple genes and their interaction with various environmental factors. Co-enzyme Q10 (Co-Q10) is essentially a vitamin or vitamin-like substance present naturally in foods and every cell of the body. Co-Q10 appears to be helpful in gingivitis. Recent studies indicate a significant improvement in all the signs and symptoms of periodontal disease. Hence the present study was conducted to test the clinical efficacy of this substance incorporated in the tooth and gum gel (Co-Q Dent) in aggressive periodontitis patients.
Keywords:-Aggressive Periodontitis, Co-enzyme Q10, bleeding gums, periodontal pocket, gingival inflammation
Original research article:-
*Singh Umesh Pratap 1 and R. Parthasarathy.2
1 Ph.D research scholar- NIMS University Jaipur Rajasthan,India.
2 Director-Faculty of Pharmacy, Kamla Nehru Institute of Management and Technology, Sultanpur, Uttar Pradesh, India.
Abstract:- Roots of Blumea eriantha DC and Blumea lacera have been used in the ayurveda and other folk medicines for the treatment of cholera and diarrhea. To justify its folklore, present study was undertaken to investigate the antidiarrhoel activity of the ethanolic extract from the roots of Blumea eriantha DC (EEBE) and Blumea lacera (EEBL.) Preliminary phytochemical screening, acute toxicity study and antidiarrhoel activity were studied on castor oil induced diarrhea and normal gastrointestinal models of rats at 250, 500 and 750 mg/kg body weight. The preliminary phytochemical screening of the ethanolic extract from the roots of Blumea eriantha DC (EEBE) results with the presence of anthraquinone glycoside, tannins, flavonoids etc.while Blumea lacera showed presence of steroids, terpenoids and alkaloids, flavonoids, saponin and absence of tannin and phnolics, LD50> 1000mg/kg. The doses of EEBE and EEBL both significantly decreased (P<0.001) the total number of diarrheal faeces. PI decreases doses dependently (250, 500 and 750 mg/kg orally) of EEBE and EEBL and was comparable with standard drug atropine sulphate. Conclusively, EEBL has more antidiarrhoel activity in comparison of EEBE but less effective when compared with atropine sulphate in experimental rats.
Keywords:-Blumea eriantha DC (EEBE)., Loperamide, Atropine. Blumea lacera (EEBL)
Original research article:-
Samatha P1, *Siva Prabodh V2, Chowdary NVS2, Ravi Shekhar2
1MSC , 2 MD, Dept. of Biochemistry, NRI Medical College and Hospital, Chinakakani, A.P- 522503, India.
Abstract:- Diabetic patients with accompanied (but often unnoticed) dyslipidemia are soft targets of cardiovascular deaths. An early intervention to normalize circulating lipids shown to reduce cardiovascular complications and mortality. Glycated hemoglobin (HbA1c) is a routinely used marker for long – term glycemic control. This investigation is an attempt to evaluate the association between HbA1c and various lipid parameters. Venous blood samples collected from 50 type 2 diabetic patients (26 males, 24 females) and serum analyzed for HbA1c, Fasting blood glucose, Total Cholesterol, Triacylglycerols, HDL-C and LDL-C. L/H risk ratio is also calculated. The levels of HbA1c (%) did not differ significantly between males (8.51 ± 1.17) and females (8.24 ± 1.89), whereas male patients had higher mean values of FBG and various lipid parameters than in females. Patients with HbA1c value >7.0 % showed direct and significant correlation with FBG, TC, LDL-C, L/H risk ratio as compared to patients with HbA1c ≤ 7.0%. There was no significant difference in TG, HDL-C between two groups of glycated hemoglobin. These findings indicate that HbA1c is utilized for screening high risk diabetic patients for early diagnosis of dyslipidemia and timely intervention with lipid lowering drugs.
Keywords:-Diabetes, Dyslipidemia, Glycated hemoglobin, Association.
Original article:-
*Narayan Shrihari1, KumudiniT.S D2, Mariraj.J3, Krishna.S3
1MD (Microbiology), Asst. Professor, 2Bact (Microbiology), Tutor, 3Professor,4 Professor and Head, Department of Microbiology, Vijayanagar Institute of Medical Sciences (VIMS), Bellary-583104,India.
Abstract:- Back ground: In recent years, fungi have been emerging more common infection in immunocompromised patients of tertiary care centers. The climate of our country is well suited for a wide varity of fungal infections. Within the limited data available, an increased incidence of invasive candidiasis, aspergillosis and zygomycosis are reported. The infection is commonly observed in patients with uncontrolled diabetes mellitus, newer technologies in medical and surgical therapies, organ transplant, use of invasive devices and broad spectrum antimicrobial agents. Objective: The retrospective analysis for a period three years was undertaken to know the prevalence of common fungal infections in a tertiary care Hospital. Material and Methods: The various clinical samples were collected from the patients presenting with clinically suspected fungal infections. The direct microscopy with potassium hydroxide (KOH) was done to visualize the presence of fungal elements and Gram staining was done for any suspected yeast infection. Fungal culture of all samples were inoculated on two different culture media; one sabourauds dextrose agar (SDA) and the other SDA with chloramphenicol and cycloheximide. Results: A total of 690 clinical samples suspected fungal etiology were included for a period of three years. Out of which corneal scraping was most common sample 478(69.28%), followed by skin scraping 105(15.22%) and nail clipping 50(7.25%). Male to Female ratio of patients is 1.56 and majority of the patients belong to age group 21-50 years. Fusarium species was the predominant fungal isolate 57(22.44%), followed by Aspergillus niger 31(12.20%), Aspergillus flavus 31(12.20%), Aspergillus species 23(9.06%), Aspergillus fumigatus 20(7.87%) and Trichophyton species 20(7.87%). Conclusion: The wet mount preparation of KOH can be used as a screening test for presumptive diagnosis of fungal infections. Laboratory confirmation should be undertaken and fungal infection must be ruled out before prescribing corticosteroids and antibacterial agents.
Keywords:- Candidiasis, aspergillosis and zygomycosis.
Original article:-
S.C.Vijayvergiya1, Arvind K.Bohra1,*Purushottam Jhanwar1, Ankur Jhanwar2
1MS, Assistant Professor, Department of Orthopedics, S.R.G. Hospital and Medical College, Jhalawar, Rajasthan, India.
2MS, Senior Resident, Department of Surgery, Govt. Medical College, Kota , Rajasthan, India.
Abstract:- Background: Injuries related to agricultural equipment are a significant cause of morbidity and mortality both in high-income and low-income countries. Agricultural work is the most prevalent type of employment in the worlds. An estimated 1.3 billion workers are working in agricultural production worldwide. Agriculture related injuries are one of the common reason for hospitalization. Aim & Objective: To study the pattern of agriculture related injured patient hospitalized in S.R.G. Hospital, Jhalawar, and give a baseline for deriving effective preventive measures for the local community. Methodology: A retrospective study was done in Orthopedic unit of S.R.G. Hospital, Jhalawar over a period of three years from 2009-2011.All the data were taken from case record of patients and determined and charted in an excel sheet. Simple frequencies and percentages were derived for various variables. Result: Most cases involved males between ages of 20-39 yrs ,with a seasonal peak seen in month of October and July. There were 8.47% patients admitted in the age group of less than 20yrs and almost comparable percentage were of older age group (9.03%).Tractor was responsible for about 36% of agriculture related injuries followed by hand-operated tools and thrasher injuries (24% and 12% respectively).Most common injuries encountered were fractures (both simple and compound) about 60%.Amputation occurred in 2.02% cases.
Keywords:-Agriculture related injuries, machinery, Rollover Protective Structure (ROPS), tractors.