DocumentsDate added
Research article:-
* Shopana Mohanarji1,2, Sudhahar Dharmalingam1,2, Anandarajagopal Kalusalingam1,2
1School of Pharmacy and Applied Science, La Trobe University, Bendigo, Victoria 3552, Australia. 2Faculty of Pharmacy, Masterskill University College of Health Sciences, Batu 9, Cheras 43200, Selangor, Malaysia.
Abstract:- Over the decades, natural source has become an important essence to discover new antimicrobial compounds to control the dramatic increase of infectious disease. In this present study, petroleum ether, chloroform, methanol, and water extracts of Lignosus rhinocerus sclerotium were obtained. All the extracts were screened for their antibacterial and antifungal activities against gram positive bacteria such as Staphylococcus aureus, Corynebacterium diphtheriae, Bacillus cereus, Stapyhlococcus epidermidis, Streptococcus pyogenes, Strepococcus viridans, Micrococcus luteus, gram negative bacteria such as Klebsiella pneumoniae, Salmonella typhi, Entorobacter aerogenes, Vibro cholera, Escherichia coli, Pseudomonas aeruginosa, Serratia marcescens, Proteus hauseri and fungi such as Candida albicans, Candida tropicalis, Candida krusei and Mucor racemosus by disc diffusion method. Antibacterial and antifungal activities of these extracts were assessed by measuring diameter of zone of inhibition and the results were compared with standard antibiotics, Amoxicillin (10µg/disc) and Fluconazole (30µg/disc) respectively. From these findings, the extracts of Lignosus rhinocerus indicated that plant possess significant antimicrobial activity against tested microbes, which could be a potential source to modern medicine to treat microbial infections.
Keywords:- Lignosus rhinocerus, Mushroom, Antibacterial, Antifungal, Disc diffusion.
Original article:-
* OMOLE, Moses Kayode Pharm. D ADEYEMI, Morenike Titilola B. Pharm.
Department of Clinical Pharmacy and Pharmacy Administration, Faculty of Pharmacy, University of Ibadan.
Abstract:- The requirement for rational use of drug (RUD) is that the right drug be used with the right dose, at the right interval and at the right duration. This study was carried out to determine the rational use of anti-asthmatic drugs and to investigate various factors that influence the selection of such drugs at the University College Hospital (UCH). The study was conducted between the period of two months of May 1st and June 30th, 2010. Four case notes of two male adults and two female adults from the medical out-patient records department were randomly selected and thoroughly studied. Patient A was prescribed 8 drugs including salbutamol and prednisolone as anti-asthmatic drugs. Patient B was prescribed 7 drugs including salbutamol and aminophylline as anti-asthmatic drugs. Patient C was prescribed 4 drugs including salbutamol as anti-asthmatic drug and patient D was prescribed 6 drugs including salbutamol, aminophylline and prednisolone as anti-asthmatic drugs. There was no potential drug interaction or adverse drug reaction documented for the patients. Other complications documented were hypertension and zeazure for patient A, diabetes mellitus for patient B, and chest infection in patient D. Although the patients were discharged and pharmacotherapy individualized, anti-asthmatics which were rationally used in the studies could be implicated by irrational use of drugs in the treatment of other complications.
Key Words:- Asthma, Rational, Prescriptions, Drugs.
Research article:-
Ms. K. Amrutha veena*, M Phil and Dr. S. Kowsalya, PhD
Department of Food Science and Nutrition, Avinashilingam University for Home Science and Higher Education for Women, Coimbatore - 641 043. India.
Abstract:- Background: There is a paucity of data regarding the micronutrient status of adolescents in Ramanathapuram district of Tamil Nadu. Aim: To evaluate the nutritional status and prevalence of micronutrient deficiency among adolescents in Ramanathapuram district of Tamilnadu. Design: Community based cross-sectional study. SETTING: Seven taluks of Ramanathapuram district, Tamil Nadu. Materials and methods: A total of 2800 infants (less than one year of age) comprising of 1400 male and 1400 female infants from all the seven taluks of Ramanathapuram district were selected at random. Anthropometric parameters such as weight, height, head circumference, arm circumference and chest circumference were measured using standardized procedures. They were clinically examined for the manifestation of deficiency signs of various micronutrientsBiochemical estimation of serum haemoglobin, vitamin A and urinary iodine were done for 5% of the adolescents. Results: Majority of the subjects belonged to lower socio-economic status and very few belonged to the high income group. Morbidities such as fever, diarrhoea and cough/cold were common among the adolescents. Clinical signs and symptoms of micronutrients deficiency were also prevalent. Mean haemoglobin levels were below normal indicating sub-clinical signs of deficiency. Conclusion: Micronutrients deficiency is still evident among the study population and intervention strategies are the need of the hour.
Keywords:-Adolescents, deficiency, Iodine ,Iron, micronutrient, vitamin A.
Original article:-
Madhav Raje1, Sangeeta Mule2.
1 MD (FMT), DFM (Family Medicine), DPM (Psychological Medicine), BA (Psychology),MA (Philosophy),DPC (Counseling), Consultant Psychiatrist& Psychotherapist, Nagpur,India.
2 Sangeeta Mule, BA (Psychology), MSW. Psychosocial Worker, Lata Mangeshkar Hospital, Hingana, Nagpur,India.
Abstract:- Introduction: In view of rising suicidal tendencies/attempts (1) study was designed to assess causal relationship of Psychosocial factors in suicidal ideation (2). It is assumed that unless psychosocial factors are treated suicide cannot be totally prevented. Method: All patients of SI were interviewed in detail in Psychiatry OPD of LMH Nagpur. Variable, psychosocial factors were (i) Alcohol abuse (ii) Financial Problems (iii) Domestic Violence (iv) Divorce or marital Separation, against which SI were measured. Data was collected through semi-structured psychiatric & psychosocial assessment. Brief psychotherapy was offered to female careers. Results: Out of 75 patients 49% disclosed psychosocial stressors. 20% patients’ revealed h/o Alcohol abuse & 14% patients disclosed financial problems. Variable, Alcohol Abuse composed of female patients who were victimized by their alcoholic husbands/family members. Domestic violence & Divorce implicated 5.33% patients each while 4% suffered from bereavement. Faulty-cognition of female careers was observed changing. Discussion: Alcohol abuse was found to trigger various psychosocial factors directly or indirectly. This study revealed 50% of Alcohol abuse cases belong to female careers. Brief psychotherapy given by clinician was found beneficial. Correction & building of cognition of female career was seen to attribute reduction in SI. Conclusion: Psychosocial factors were implicated for SI among 49% patients. Alcohol was the major risk factor to cause SI directly or indirectly. Impact of attribution of psychosocial factors on SI was almost similar to that of disease process. Biological impact of psychosocial factors especially on female careers was observed.
Keywords:- Suicidal Ideation, Attribution, Faulty Cognition, Psychosocial factors, Female career.
Original research article:-
Kemfang Ngowa Jean Dupont (Senior lecturer)1,2, Kasia Jean Marie (Professor)1,2, Nke Zibi H. (Resident)1 , Neng HT. (Resident)1.
1Department of Obstetrics & Gynecology, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, P.O. Box 1364, Yaounde, Cameroon. 2Yaounde General Hospital, P.O. Box 5408, Yaounde, Cameroon.
Abstract:- Background: Black women are nearly three times as likely as white women to develop uterine fibroids during the childbearing period and usually presents multiple and very large uterine fibroids. Aims: This study aimed to evaluate the adnexal adhesions formation after abdominal myomectomy among African women. Settings and design: Retrospective and descriptive study conducted at Yaounde General Hospital, Cameroon during the period of January 2004 to December 2009. Materials and methods: We reviewed 140 cases of childbearing desirous women who underwent second-look laparoscopy after an abdominal myomectomy at Yaounde General Hospital. Results: Adnexal adhesions were present in 123 (87.85%) patients. The posterior uterine wall incision was associated with more adhesions formation than those on the fundus or anterior wall (100% vs 81.82% vs 88.89%; P 0.035). Myomectomies performed on uterus larger than 14 weeks gestation resulted in significantly higher adhesion scores (22.76% vs 03.25%; P 0.000). The existence of more than two uterine incisions and the presence of adhesions prior to myomectomy were found to result in more severe adhesions (23.57% vs 2.43%; 20.32% vs 2.43%; P 0.000). Conclusions: African women have high incidence of post operative adhesions formation following myomectomy. It will be attractive to evaluate also in these African women the efficacy of a resorbable hydrogel for reduction of post-myomectomy adhesions.
Keywords:- Adnexal, adhesion; myomectomy; African; women.