DocumentsDate added
Short communication:-
*Razieh Hassankhani.
*Law Department ,Bu Ali Sina University ,Hamedan, Islamic Republic of Iran.
Abstract:- Genetic science is one of the branches of biology. By way of existing contacts and discussion in this field, we may discover similarity and dissimilarity of two living beings. In many parts of the world, the level of life expectancy has increased, while mortality rate has declined, which is mostly resulted from increased scientific knowledge and advanced equipment in human life that is in turn owed greatly to science of genetic engineering. Freedom in the domain of Genetic is mentioned in article 2 of Universal Declaration of Human Rights:"Everyone is entitled to all the rights and freedoms set forth in this Declaration, without distinction of any kind, such as race, color, sex, language, religion, political or other opinion, national or social origin, property, birth or other status." but this matter should be considered from the view point of the children themselves, which under the convention of children rights, the children must have desired personality growth and this processes begin from the early stages of life.
Keywords:- Gen, Genetics, convention of children rights.
Original article:-
Bhanwar Singh Takhar1, Sanjeev Saxena2 1PhD Scholar, Singhania University, Pacheri Bari, Jhunjhunu, India. 2Professor & PhD Guide, Singhania University, Pacheri Bari, Jhunjhunu, India.
Abstract:- Background Plantar fasciitis (PF) is an overuse injury causing inflammation at the origin of the plantar fascia and surrounding perifascial structures, such as the calcaneal periosteum, which affects about 10% of the population at least in one moment in life. Successful treatment of plantar fasciitis usually requires combined treatment modalities, rather than administering only one treatment at a time. This study is aimed to examine the effect of medial arch support with ultrasound therapy and exercises to manage plantar fasciitis. Method 10 subjects of both genders, with mean ± SD age of 44.90 ± 4.25years were selected on the basis of inclusion and exclusion criteria. The subjects were under a structured 6 weeks exercise program, medial arch supports and ultra sound therapy for each day for 6-days a week. Result There is statistically significant reduction in foot functional score index measures and improvement in range of motion of ankle joint with p value less than 0.05 after 6 weeks of supervised exercise program, ultra sound therapy and medial arch support. Conclusion The results of the present study, suggest that medial arch support with ultrasound therapy and exercise are effective for plantar fasciitis.
Keywords:-Plantar Fasciitis, Ultra Sound Therapy, Medial Arch Support.
Research article:-
*M. Srujan Kumar1, Binayak Das1, S.V.S.Rama Raju2
1Department of Pharmaceutics, Samskruti college of Pharmacy,Kondapur,R.R District,Hyderabad,India.
2Department of Pharmaceutics, C.L.Baid Metha College of pharmacy, Chennai, India.
Abstract:- Compaction of multiparticulate, commonly called MUPS, is one of the more recent and challenging technologies that combine the advantages of both tablets and pellet-filled capsules in one dosage form. Venlafaxine is an anti depressant, having an elimination half-life of 5±2 hrs and its maximum daily dose is 300mg. Since the drug belongs to BCS class I, it is necessary to retard dissolution to ensure extended release of drug. The objective of the study is to prepare venlafaxine extended release pellets by extrusion spheronization technology, coating them with mixture of rate controlling polymers Ethyl cellulose and different grades of (Hydroxy propyl methyl cellulose (HPMC) using Wurster process to achieve the desired dissolution pattern and compressing the pellets into tablets. The pellets were analyzed for the parameters such as bulk density, tapped density, compressibility index, Hausner’s ratio and the results were found to be within the limits. Drug release rate was more when compared with the innovator sample. The Venlafaxine hydrochloride extended release pellets were compressed into the tablets. The dissolution profile of the prepared Venlafaxine hydrochloride extended release tablets were compared with that of Innovator (VENLAR). Finally conclude like extended release pellets in tablets of formulation (F9) have more drug release rate rather than innovator (VENLAR) and it have better Bioavailability.
Keywords:- Extrusion and Spheronization, HPMC, MUPS, multiparticulate, wurster process.
Case report:-
Sunita Gajbhiye, 1 , Gopal Agrawal 1, S. N. Shrikhande 2
1 MD, Assistant Professor,2 MD, Associate Professor, Department of Microbiology, Indira Gandhi Government Medical College, Nagpur 440018,India.
Abstract:-Nocardia is an uncommon pathogen in immunocompetent patients; however, it has been increasingly recognized as a significant opportunistic pathogen in immunocompromised individuals. A 35 year old male patient presented with fever and multiple erythematous swellings over right supraclavicular and post auricular region. The swellings were with multiple discharging sinuses. Patient is a known case of miliary tuberculosis and is HIV seropositive. Gram stain of pus showed presence of slender, gram positive, branching, filamentous bacilli. Modified Ziehl Neelsen stain revealed numerous acid fast branching filamentous organisms with beaded appearance. On culture the isolate was identified as Nocardia asteroides.
Keywords:-Nocardia asteroids, generalized nocardiosis, infection in immunocompromised.
Original research article:-
Kemfang Ngowa Jean Dupont (Senior lecturer)1,2, Kasia Jean Marie (Professor)1,2, Nke Zibi H. (Resident)1 , Neng HT. (Resident)1.
1Department of Obstetrics & Gynecology, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, P.O. Box 1364, Yaounde, Cameroon. 2Yaounde General Hospital, P.O. Box 5408, Yaounde, Cameroon.
Abstract:- Background: Black women are nearly three times as likely as white women to develop uterine fibroids during the childbearing period and usually presents multiple and very large uterine fibroids. Aims: This study aimed to evaluate the adnexal adhesions formation after abdominal myomectomy among African women. Settings and design: Retrospective and descriptive study conducted at Yaounde General Hospital, Cameroon during the period of January 2004 to December 2009. Materials and methods: We reviewed 140 cases of childbearing desirous women who underwent second-look laparoscopy after an abdominal myomectomy at Yaounde General Hospital. Results: Adnexal adhesions were present in 123 (87.85%) patients. The posterior uterine wall incision was associated with more adhesions formation than those on the fundus or anterior wall (100% vs 81.82% vs 88.89%; P 0.035). Myomectomies performed on uterus larger than 14 weeks gestation resulted in significantly higher adhesion scores (22.76% vs 03.25%; P 0.000). The existence of more than two uterine incisions and the presence of adhesions prior to myomectomy were found to result in more severe adhesions (23.57% vs 2.43%; 20.32% vs 2.43%; P 0.000). Conclusions: African women have high incidence of post operative adhesions formation following myomectomy. It will be attractive to evaluate also in these African women the efficacy of a resorbable hydrogel for reduction of post-myomectomy adhesions.
Keywords:- Adnexal, adhesion; myomectomy; African; women.