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Original research article:-Forensic medicine
S Manjunath1,*Shankar M Bakkannavar2,Pradeep Kumar G3,Vrinda J Bhat4,Nayana Prabhu5,Asha Kamath6,RaghavendraBabu Y P7
1Associate Professor, Department of Forensic Medicine, Kasturba Medical College, Manipal University, Manipal, India.
2Assistant Professor, Department of Forensic Medicine, Kasturba Medical College, Manipal University, Manipal, India.
3Professor and Head, Department of Forensic Medicine, Kasturba Medical College, Manipal University, Manipal, India.
4Professor and Head, Department of Forensic Medicine, Shimoga Institute of Medical Sciences, Shimoga,India.
5Associate Professor, Department of Prosthodontics, Manipal College of Dental Sciences, Manipal University, Manipal, India.
6Selection Grade Lecturer, Department of Community Medicine, Kasturba Medical College, Manipal University, Manipal, India.
7Associate Professor, Department of Forensic Medicine, Kasturba Medical College,Mangalore,ManipalUniversity,India.
Abstract:- Palatoscopy or Palatal rugoscopy is the name given to the study of palatal rugae in order to establish a person’s identity. Rugoscopy finds application in the field of anthropology, comparative anatomy, genetics, forensic odontology, prosthodontics and orthodontics. The present study is an attempt to determine the differences in the rugae pattern among the Indian males and females in a small portion of a population. 63 subjects, 32 males and 31 females in the age group 17-25 years formed the materials for the study. After a written informed consent, maxillary dental casts were taken and interpretation of the rugae pattern was done as per classification by Thomas and Kotze. It was noted that the Indian females had more number of rugae on the right side of the palate than the male counterparts. Curved and straight shapes were predominant among the females whereas the wavy pattern was more common among the males. Their uniqueness to individuals has been recognized as providing a potentially reliable source of identification.
Keywords:-Forensic odontology; Identification; rugoscopy.
Research article:-
Ajay Patil1, Vijay Bhawe,1 Jagannath J Kadam2,K.George A3 and Manohar V Lokhande4 1Department of Chemistry, Bhavan’s College , Andheri (W),Mumbai 400058, India. 2Department of Chemistry, Bharati Vidyapeeth College of Engineering, Navi Mumbai-400614,India. 3Department of Chemistry, SIES College, Sion (W) Mumbai-400022, India. 4Department of Chemistry, Sathaye College, Vile Parle (E) Mumbai-400057, India.
Abstract:- The paper describes the synthesis of Hydrochlorothiazide which shows great therapeutic use as diuretic i.e. anything that promotes the formation of urine by kidney. Diuretics cause a person to ‘lose water’. They do so by diverse means including. The synthesis was carried out using four different hydrotropes. The effect of various hydrotropes on yield, rate constant and activation energy at various temperatures and concentrations were studied.
Key words:- Hydrotropes, Xylene sulfonic acid (XSA), Cumene sulfonic acid (CSA), (n-BBSA): n-Butyl benzene sulfonic acid (n-BBSA), Isobutyl benzene sulfonic acid (I-BBSA), 1H NMR, IR.
Review article:- Periodontology
Vidya Dodwad1, Shubra Vaish2, *Mehak Chhokra3, Aakriti Mahajan3.
1MDS, Professor and HOD,2 MDS,Reader,3 MDS, final year students ,Department of Periodontology, ITS-CDSR, Ghaziabad, India.
Abstract:- Periodontitis is a disease attributable to multiple infectious agents and interconnected with cellular and humoral host responses. It results from extension of the inflammatory process initiated in the gingiva to the supporting periodontal tissues. Periodontal pockets provide natural reservoir bathed by gingival crevicular fluid that is easily accessible for the insertion of a delivery device. Controlled release delivery of antimicrobials is a therapeutic intervention directly into periodontal pockets and is available in various forms like gels, monolithic devices, irrigation systems, chips, films, strips, microspheres, fibres etc. It is an effective monotherapy that has evoked a great interest and appears to hold a sound promising result in periodontal treatment. It does not substitute the local instrumentation but acts as an adjunct to it. These local agents bypass the adverse effects of systemically administered antimicrobial agents, as well stabilize the attachment apparatus and reduce the probing depth thereby allowing better control and management of periodontal disease.
Keywords:- Gingivitis, Periodontitis, Local drug delivery, Periodontal Pocket.
Research article:-Periodontology
Vidya Dodwad1, * Shubhra Vaish2, Prashant Tyagi 3 .
1MDS, Professor and HOD,2 MDS,Reader,3 MDS, final year students ,Department of Periodontology, ITS-CDSR, Ghaziabad, India.
Abstract:- Background: Recent developments suggest that the local delivery of antimicrobials into periodontal pockets can improve periodontal health. AZM has a wide antimicrobial spectrum of action towards anaerobic bacteria as well as gram negative bacilli. It is effective against periodontal pathogens like Aggregatibacter Actinomycetemcomitans and Porphyromonas gingivalis. Therefore the present study is as undertaken to investigate the clinical effectiveness of Azithromycin at 0.5% concentration in an indigenously prepared bioabsorbable controlled release gel as an adjunct to non surgical mechanical therapy in the treatment of chronic periodontitis. Method: Thirty sites in patients with chronic periodontitis and probing depth 4-6mm were categorized randomly into two treatment groups: Scaling and Root Planing (SRP) plus 0.5% Azithromycin gel (group 1) and SRP only (group 2). Clinical evaluation was undertaken using the gingival index of Loe and Silness and plaque was assessed using the Turesky et al. modification of Quigley Hein Index at baseline and 21 days. Pocket probing depth and clinical attachment level were also measured using customized acrylic stents. Result: Both therapies resulted in significant improvements. Mean reduction in Gingival Index from baseline to 21 days was 1.20±.41 and .73±.45 in group 1 and group 2 respectively. Plaque Index also improved through the study period in both groups i.e. 0.86±.51 in Group 1 and 1.6±.97 in group 2. Mean probing depth reduced significantly with SRP plus AZM gel application in group 1 i.e. 2.1±.91mm as compared to 1.0±1.06mm achieved with SRP alone. a significant gain in mean CAL gain was observed in the test group (1.8±.63mm) as compared to control group (1.0±1.06mm). Conclusion: Although both treatment strategies seem to benefit patients, the adjunctive use of 0.5% of AZM showed significant results with respect to clinical parameters.
Keywords:-Azithromycin, Local drug delivery, Periodontitis, Scaling and Root planing.
Research article:-Medical microbilogy
Nageswari.Rajesh.Gandham1, Pallavi Subhash Tatte2, Savita Vivek Jadhav3, Mukesh Sharma4 1Professor3 Assistant Prof., 4 PG student, Department of Microbiology, Pad.Dr.D Y Patil Medical College, Pune 411018, India.
2Assistant Prof. Dept of Microbiology,Dr.Panjabrao Deshmukh Memorial College Amravati-444603, India.
Abstract:- Introduction: Ottorhoea is a common presenting complaint of patients seeking medical attention .Otitis in all it’s forms has a varied microbial etiology which influences the selection of an efficacious anti microbial agent. Hence the objective of this study was to identify the etiological agents in patients coming with complaints of otorhoea. Methods: A total of 150 cases were enrolled in the study conducted in the department of Microbiology, Padmashree Dr D Y Patil Medical College, Pimpri Pune from patients attending OPD in the department of Ottolaryngology. Sterile cotton swabs were used to collect samples from patients complaining of ear discharge. Samples were processed by standard microbiology protocols by traditional methods including microscopy, culture, biochemicals. Antibiotic Susceptibility was done by Kirby-Bauer disc diffusion method. Fungal culture was done on Sabouraud Dextrose Agar(SDA). Results and Observations: Of 150 cases studied, 121 were culture positive and remaining culture negative. A total of 161 organisms was recovered from 121 patients. Staphylococcus aureus was recovered in 68 cases, fungal culture was positive in 38 followed by Pseudomonas in 27.Ciprofloxacin and Amikacin susceptibility was highest in Gram negatives. While Gram positive organisms showed high susceptibility to Cefuroxime and Vancomycin. Conclusions: S.aureus was the most common bacteria isolated. Susceptibility to Ciprofloxacin ,Cefuroxime and Amikacin was found to be high.
Key Words :- Ottorhoea, S.aureus, antibiotic susceptibility.