DocumentsDate added
Research article:-Orthopedics
* Arvind K. Bohra1, S.C.Vijayvergiya1, Rajesh Malav2, Purushottam Jhanwar1.
1 Assistant Professor,2S R, Department of Orthopedics, S.R.G. Hospital and Medical College, Jhalawar, Rajasthan, India.
Abstract: Aim: To compare the functional, clinical and radiological outcomes between open reduction with internal fixation of intrarticular fracture distal radius with locking compression volar T- plate and non locking volar T- plate. Methods: The study included patients with comminuted unstable intra-articular distal radius fracture treated by open reduction and internal fixation from Sept. 2008 to Sept. 2011, Out of total cases operated in Orthopedic department of S.R.G. Hospital , Jhalawar, we have included 22 cases of fracture distal end radius by open reduction and internal fixation . 11 were operated by using non-locking volar T- plate and 11 were operated with locking compression volar T- plate. Follow up of both the groups were done for 24-26 wks.The two groups were compared for range of motion(ROM) , clinical and radiological grounds. Results: All patients were assessed clinically and radio graphically after a mean follow-up duration of 24-26 weaks . Results were obtained according to functional criteria of Green and O’Brien Point System . We found that the clinical and radiological outcomes for the 2 groups were not significantly different. Conclusion: Open reduction and internal fixation of of distal radius fracture with volar T- plate radius locking and nonlocking in adults can restore articular congruity and result in good to excellent function. Though in severe osteoporotic fracture and severe cummunited fracture locking type volar T- plate is a better alternative mode of treatment.
Keywords:- Open reduction and internal fixation , range of motion, volar T- plate, Green and O’Brien point system, Sarmiento’s anatomical criteria.
Original research article:-Biochemistry
*Siva Prabodh V1 , Padma Vijaya Sree A2 , Sarma DVHS2 , Siva Reddy M2
1 Dept. of Biochemistry, NRI Medical College and General Hospital, Chinakakani, A.P, India
2 Dept. of Biochemistry, Kurnool Medical College and General Hospital, Kurnool, A.P, India .
Abstract:- Objective: To determine whether serum (pseudo)cholinesterase levels has any diagnostic and prognostic value in acute organophosphorus poisoning. Design: cohort (prospective) study Patients: 40 consecutive patients admitted to ICU for acute organophosphate poisoning. Measurements: Serial measurement of Serum Cholinesterase levels in all patients – 4 times, at the time of admission before administration of PAM(Pyridine aldoxime methiodine), 24hrs after administration of PAM, 48hrs after administration of PAM, 72hrs after administration of PAM. Results: serum cholinesterase levels were significantly decreased in acute organophosphorus poisoning cases when compared to controls and also there is regeneration of serum cholinesterase levels after administration of PAM by 22 %, 45% and 73% after 24hrs, 48hrs and 72 hrs. Conclusion: serum cholinesterase levels have diagnostic value as their levels are significantly decreased in organophosphorus poisoning cases and also prognostic value as there is regeneration of serum cholinesterase levels after administration of PAM.
Key words: -Serum cholinesterase, organo phosphorus poisoning, Pralidoxime, PAM.
Review article:-
* Adesina Adeolu Jonathan .
Department of Chemistry. Ekiti State University,PMB 5363, Ado Ekiti. Nigeria.
Abstract:- The world wide diversity of dietary intakes of n-6 and n-3 fatty acids influences tissue compositions of n-3 long chain fatty acids: eicosapentaenoic, docosapentaenoic and docosahexaenoic acids and risk of cardiovascular and mental illness. Linoleic acid (LA) and alpha- linolenic acid (ALA) belong to the n-6 (Omega -6) and n-3 (Omega- 3) series of PUFA (polyunsaturated fatty acids) respectively. They are defined ‘’ essential’’ fatty acids since they are not synthesized in the human body and are mostly obtained from the diet. Food sources of ALA and LA are mostly vegetable oils, cereals and walnuts. Recent advances in chromatographic identification of CLA isomers, combined with interest in their possible properties in promoting human health (e.g., cancer prevention, decreased atherosclerosis, improved immune response) and animal performance (e.g., body composition, regulation of milk fat synthesis, milk production further promotes the interest in research on PUFA . This review deeply probes into the chemistry, health benefits, and risks of n-3 and n-6 PUFA linking their biological functions to biochemistry and metabolism as well as revising the important cardioprotective effects of n-3in the secondary prevention of sudden cardiac death due to arrhythmias.
Keywords:- Classification, biosynthesis, health implications, n-3 and n-6 PUFAs.
Research article:-Periodontology
Vidya Dodwad1, * Shubhra Vaish2, Prashant Tyagi 3 .
1MDS, Professor and HOD,2 MDS,Reader,3 MDS, final year students ,Department of Periodontology, ITS-CDSR, Ghaziabad, India.
Abstract:- Background: Recent developments suggest that the local delivery of antimicrobials into periodontal pockets can improve periodontal health. AZM has a wide antimicrobial spectrum of action towards anaerobic bacteria as well as gram negative bacilli. It is effective against periodontal pathogens like Aggregatibacter Actinomycetemcomitans and Porphyromonas gingivalis. Therefore the present study is as undertaken to investigate the clinical effectiveness of Azithromycin at 0.5% concentration in an indigenously prepared bioabsorbable controlled release gel as an adjunct to non surgical mechanical therapy in the treatment of chronic periodontitis. Method: Thirty sites in patients with chronic periodontitis and probing depth 4-6mm were categorized randomly into two treatment groups: Scaling and Root Planing (SRP) plus 0.5% Azithromycin gel (group 1) and SRP only (group 2). Clinical evaluation was undertaken using the gingival index of Loe and Silness and plaque was assessed using the Turesky et al. modification of Quigley Hein Index at baseline and 21 days. Pocket probing depth and clinical attachment level were also measured using customized acrylic stents. Result: Both therapies resulted in significant improvements. Mean reduction in Gingival Index from baseline to 21 days was 1.20±.41 and .73±.45 in group 1 and group 2 respectively. Plaque Index also improved through the study period in both groups i.e. 0.86±.51 in Group 1 and 1.6±.97 in group 2. Mean probing depth reduced significantly with SRP plus AZM gel application in group 1 i.e. 2.1±.91mm as compared to 1.0±1.06mm achieved with SRP alone. a significant gain in mean CAL gain was observed in the test group (1.8±.63mm) as compared to control group (1.0±1.06mm). Conclusion: Although both treatment strategies seem to benefit patients, the adjunctive use of 0.5% of AZM showed significant results with respect to clinical parameters.
Keywords:-Azithromycin, Local drug delivery, Periodontitis, Scaling and Root planing.
Research article:-Engg Chemistry
M. Suneetha and K. Ravindhranath*
Department of Engg. Chemistry and Post Graduate Chemistry, Bapatla Engineering College (Autonomous), BAPATLA-522101, Guntur Dt., A.P., India.
Abstract:-The sorption abilities of powders of leaves, stems or ashes of Eichhornia plant have been explored in extracting Ammonia from polluted waters. Physicochemical parameters such as pH, sorbent concentration and equilibration time have been optimized for the maximum extraction of Ammonia. Successful procedures have been developed in removing quantitatively more than 80.0% of Ammonia from simulated waters. Anions like Chlorides, Fluorides, Sulphate, Phosphate and Carbonates have shown marginal interference while cations like Ca2+, Mg2+ Cu2+, Fe2+, Zn2+and Ni2+ have interfered to some extent. However, the % of extractability of Ammonia never comes down 67.0%. The adoptability of the methodologies developed in this work are tested with diverse samples collected from industrial effluents and naturally existing polluted lakes and it is found that the procedures are remarkably successful.
Keywords:- Ammonia, pollution control, bio-sorbents, applications.