DocumentsDate added
Research article:- ENT,
Minutha R1* and Sriram Nathan2.
*1MBBS, MS, Assistant Professor, 2MBBS, DLO, Dip N B (ENT), Senior Resident, Dept of ENT, Department of ENT, Madha Medical college, Chennai, India.
Abstract:- Background: unilateral acute conductive hearing loss is a unique entity in such that in most of the cases the diagnoses is confirmed and in a majority of cases is amenable to treatment. The common causes include traumatic perforation of the ear drum and otitis media with effusion. Other causes include unilateral Otosclerosis and traumatic dislocation of ossicles. Lesser common causes include post traumatic concussion and temporal bone fracture. The presentation is usually an acute (defined arbitrarily as less than three weeks) onset of hearing loss and confirmed by examination. The diagnostic work up includes audio logical evaluation and imaging studies such as HRCT (high resolution computerized tomography). The management is tailored to the cause and in most of the cases the recovery is satisfactory. Objective: To enumerate and evaluate two hundred cases of unilateral conductive hearing loss and to consider the management strategies.
Keywords:- Unilateral conductive hearing loss, pure tone audiometry.
Case Report:- Pathology
*El fatemi Hinde1, Bennani Amal1, Hammas Nawal1, Tazi Fadl2, Amarti Afaf1, Elfassi Jamal2. 1Department of pathology, Hassan II teaching hospital, Fez, Morocco.
2Department of urology, Hassan II teaching hospital, Fez, Morocco.
Abstract:- Introduction: Primary renal lymphoma (PRL) as a clinical entity is not undisputed because the kidneys do not contain lymphatic tissue and the mechanism of development of PRLs is unclear. Most of the few cases reported showed rapid systemic progression and a poor prognosis. Although there are no clearly defined diagnostic criteria for renal lymphomas, abdominal and thoracic computed tomography as well as renal and bone marrow biopsy are recommended. A case of renal lymphoma is reported and their diagnosis and management discussed. Case report: A 23-year-old woman was admitted in our institution with a 4-month history of left flank pain, and weakness. She had no relevant past medical history. Physical examination showed a painful resistance on the left flank. An abdominal computed tomography (CT) scan revealed large left renal mass of 8 cm in the lower pole with infiltration of psoas muscle. A CT-guided renal biopsy was performed. Histological and immunohistochemical studies showed diffuse large B-cell lymphoma (DLBCL). Conclusion: PRL represents a rare entity which must nevertheless be considered in cases of unusual renal masses or otherwise unexplained renal symptoms. If diagnosed early, cure is possible, and multimodal treatment should be considered.
Key Words :- Kidney / primary lymphoma / DLBCL / immunohistochemistry.
Research article:-Biochemistry
1*Dr. Lokhande Suryabhan L, 2 Dr. Iyer Chandrashekhar M, 3 Dr. Shinde Ratnendra R, 4 Dr. Nandedkar Prerna D, 5 Dr. Kamble Mahendra T.
1*MD Biochemistry; Assistant professor, Department of Biochemistry Government Medical College Nagpur, India.
2MD Biochemistry; Professor, Department of Biochemistry,Government Medical College Nagpur, India.
3M.D. Preventive and Social Medicine; Professor and Head, Department of Preventive and Social Medicine, Seth G.S. Medical College and Hospital Mumbai, India.
4,5MD Biochemistry; Assistant professor, Department of Biochemistry Government Medical College Nagpur, India.
Abstract:- Background and Objectives: Type 2 Diabetes Mellitus (Type 2 DM) characterised by relative insulin deficiency or insulin resistance is associated with glucose intolerance, hypertension, a unique dyslipidemia, a procoagulant state, and an increase in macrovascular disease. The present study was conducted to assess the significance of Apolipoprotein B in cardiovascular diseases (CVD) and complications. Materials and Methods and Statistical Analysis: 50 diagnosed cases of type 2 DM in the age group 35-65 years were included in the study and 50 age and sex matched healthy controls were taken as controls. In both the groups, we have measured serum levels of traditional lipid parameters comprising of total cholesterol (TC), triglyceride (TG), HDL-C, low density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo-B) and waist-hip ratio (WHR) as cardiovascular risk factors. Statistical analysis was done by students unpaired‘t’-test and linear regression analysis and correlation. Results: The results of this study shows significant increased level of serum total cholesterol, TG, LDL-C and VLDL-C and Apo-B in type 2 DM patients as compared to controls (p<0.001). While Serum HDL-C level was significantly lower in type 2 DM patients as compared to controls (p<0.001). The waist hip ratio of Type 2 DM patients was found to be significantly higher as compared to controls. Conclusion: The findings of the present study indicated that apolipoprotein B (Apo-B) as a cardiovascular risk factors are significantly elevated in type 2 DM patients as compared to controls and apolipoprotein B (Apo-B) significantly elevated even if lipid profile parameters such as LDL-C and HDL-C were found to be normal, signifying routine estimation of apolipoprotein B (Apo-B), in addition to traditional lipid parameters in the cardiovascular risk assessment in Type 2 Diabetes Mellitus.
Key Words:- Type 2 Diabetes Mellitus (Type 2 DM), Apolipoprotein B (Apo-B), Traditional lipid parameters, Cardiovascular disease (CVD), Waist-hip ratio (WHR).
Original article:-Periodontology and oral impantology
Swati Nagpal1* ,Vidya Dodwad2, Shubhra Vaish3
1 Post graduate Student, 2Professor and HOD, 3Reader, Department of Periodontology & oral implantology, I.T.S. Centre for Dental Studies and Research, Delhi-Meerut Road, Murad Nagar, Ghaziabad- 201206, India.
Abstract:- Periodontal disease caused by dental plaque which is a biofilm of mixed aetiology is one of the most prevalent diseases in oral cavity caused by periodontopathic bacteria . Periodontits is conventionally treated with mechanical debridement procedures and adjunctive antimicrobial therapy. Photodynamic therapy is a novel non invasive therapeutic approach with increased pathogen and site specificity. Photodynamic therapy involves use of photosensitzer that is activated by exposure to light of specific wavelength to form toxic oxygen species thereby causing localized photo damage and cell death. Application of photodynamic therapy in periodontics such as pocket debridement, gingivitis, aggressive periodontitis continue to evolve into a mature clinical treatment modality, and is considered as a promising novel approach for eradicating pathogenic bacteria in periodontitis.
Keywords:-Novel treatment, antimicrobial photodynamic therapy, Periodontitis.
Research article:-Clinical pharmacy
OMOLE, Moses Kayode1 Pharm. D. & OWODUNNI, Khadijat Oluwatoyin2 M. Pharm.
1Department of Clinical Pharmacy and Pharmacy Administration, University of Ibadan, Nigeria.
2Department of Pharmacy,University College Hospital(UCH),Ibadan ,Nigeria.
Abstract:- This prospective study investigated nursing mothers’ knowledge and factors influencing compliance there with immunization regimen in a state government-owned children hospital – Oni Memorial Children Hospital, Ibadan, Oyo State, Nigeria on Jan 5th, 2005. The study population comprised of mothers who had children aged between 0-24 months. One hundred and forty (140) nursing mothers who consented were randomly selected from 210 nursing mothers that daily visited the clinic on immunization day of January 5th, 2005 with structured questionnaires administered. There were 71.4% mothers having enough knowledge on immunization regimen compliance and 28.6% mothers without enough knowledge. 38.6% mothers with post-secondary education complied as a against 3.6% mothers with the same post secondary education who did not comply. 45.0% mothers viewed health workers’ attitudes as pleasant while 8.6% mothers perceived otherwise. 46.4% mothers employed by various organizations complied as against 27.9% self-employed mothers who did not comply. 28.6% mothers presenting their third baby at the time of study complied while 2.9% of mothers with their third baby did not comply. Five hypotheses were tested using chi-square at 0.05 level of significance, and all the hypotheses were rejected. Though, it was discovered that most mothers studied had enough knowledge on the common childhood diseases as well as the importance of immunization in combating such, several factors have been found that can influence compliance with the immunization regimen.
Keywords:-Immunization, Vaccines, Mothers’ Knowledge, Compliance, Non compliance South West Nigeria.