DocumentsDate added
Case report:-
Shetty Prathvi1, Tauro Leo Francis2*., Alva Ashwin keshva3 & Jayaram Jnaneshwari4
1,3Assistant professor,2Professor,4Senior Resident, Department of surgery Father Muller Medical college and Hospital ,Kankanady,Mangalore-575002,Karnataka,India.
Abstract:- Castleman's disease is a very rare disorder characterized by non-cancerous growths that may develop in the lymph node tissue at a single site or throughout the body. It tends to produce cytokines due to few B cells hyper proliferation. Although officially not considered a cancer, it is similar to lymphoma due to over growth of lymphoctes in this disease. We report a case of 40yr young lady with a right upper neck swelling which was cystic in consistency and on ultrasound scanning queried to be a branchial cyst threw a pathological surprise as castleman’s disease.
Key words:- Castleman's disease ; lymphoproliferative disorder ;angiofollicular lymph node hyperplasia.
Research article:-periodontics
Rosaiah Kanaparthy1*,Aruna Kanaparthy2 and Kamala Devi3
1Professor & HOD, Department of periodontics,2Reader,Conservative Dentistry & Endodontics, Peoples Dental Academy, Bhopal-462037, Madhya Pradesh, India.
3Principal & HOD, Govt Dental college & Hospital, Department of Periodontics & Oral Implantology, Hyderabad-500001, Andhra Pradesh, India.
Abstract:- Purpose: The present study was envisaged to compare the efficacy of adjunctive use of Azithromycin with scaling and root planing (SRP) the adjunctive use Amoxicillin and SRP, and SRP alone in the treatment of chronic periodontitis. To correlate the use of N-Benzoyl DL-Arginine 2- Naphthylamide (BANA) hydrolysis test and percentage of spirochete count with the periodontal parameters before and after periodontal therapy Methods: 30 subjects with chronic periodontitis were randomly selected and divided into three groups as follows. Group I: Subjects treated with scaling and root planing (SRP) alone. Group II: Subjects treated with SRP and systemic administration of Amoxicillin (SRP + AMOX). Group III: Subjects treated with SRP and systemic administration of Azithromycin (SRP + AZM). Periodontal parameters comprising of plaque index, bleeding index, probing pocket depth, clinical attachment level and microbiological parameters comprising of spirochete count and BANA test scores were assessed at base line and six weeks after completion of periodontal therapy for subjects in all the three groups. Results: The reduction in post-treatment scores as compared to pre-treatment scores of plaque index, bleeding index, pocket depth, clinical attachment levels and spirochete count was highly significant in all the groups(p<0.01). Conclusions: BANA hydrolysis is a reliable marker of periodontal disease as it has proved to be a suitable test for detection of spirochetes. The judicious use of systemic antibiotics in the treatment of chronic periodontitis may provide an additional benefit in the clinical outcome compared to SRP alone.
Key Words:- Amoxicillin , Azithromycin, Chronic Periodontitis, N-Benzoyl DL-Arginine 2- Naphthylamide.
Research article:- ENT,
Minutha R1* and Sriram Nathan2.
*1MBBS, MS, Assistant Professor, 2MBBS, DLO, Dip N B (ENT), Senior Resident, Dept of ENT, Department of ENT, Madha Medical college, Chennai, India.
Abstract:- Background: unilateral acute conductive hearing loss is a unique entity in such that in most of the cases the diagnoses is confirmed and in a majority of cases is amenable to treatment. The common causes include traumatic perforation of the ear drum and otitis media with effusion. Other causes include unilateral Otosclerosis and traumatic dislocation of ossicles. Lesser common causes include post traumatic concussion and temporal bone fracture. The presentation is usually an acute (defined arbitrarily as less than three weeks) onset of hearing loss and confirmed by examination. The diagnostic work up includes audio logical evaluation and imaging studies such as HRCT (high resolution computerized tomography). The management is tailored to the cause and in most of the cases the recovery is satisfactory. Objective: To enumerate and evaluate two hundred cases of unilateral conductive hearing loss and to consider the management strategies.
Keywords:- Unilateral conductive hearing loss, pure tone audiometry.
Review article:-Periodontology and Oral Implantology
1*Sonakshi Gupta and 2 Vidya Dodwad.
1*Postgraduate student (III Yr), Department of Periodontology and Oral Implantology, I.T.S.-CDSR, Muradnagar, Ghaziabad,U.P,India.
2MDS, Professor and Head, Department of Periodontology and Oral Implantology, I.T.S.-CDSR, Muradnagar, Ghaziabad, U.P,India.
Abstract:- Tetracyclines belong to a notable class of biologically active and commercially valuable compounds. Chemically modified tetracyclines are one such group of drugs which have been viewed as potential host modulating agents. A major advantage of CMTs (unlike tetracyclines) is the lack of antimicrobial activity and development of antibiotic resistant microbial flora in vivo in long term therapy. The non-anti-microbial properties of chemically modified tetracyclines (CMTs) have shown a great promise in their therapeutic value in field of dentistry. Among them CMT-1, CMT-3 and CMT-8 have been tested for periodontal applications. Recent studies have shown that CMT-3 and CMT-8 inhibit tumor metastasis and arthritis affected synoviocyte invasion in animal models.
Keywords:- Chemically modified Tetracyclines, Host Modulating agents.
Original Research article:-Medical microbiology
1*Dr Alka Nerurkar, 2Dr Priti Solanky, 3Dr Shanta S. Naik.
1* (M.D. Microbiology) Associate Professor, Dept. of Microbiology, GMERS Medical College, Valsad, 2(M.D. Community Medicine) Assistant Professor, Dept. of Community Medicine, GMERS Medical College, Valsad, 3(M.D. Pathology & Bacteriology) Consultant Pathologist & Bacteriologist Dr Shanta Naik’s Pathology Laboratory, Bandra West, Mumbai- 400 050,India.
Abstract:- Background: Urinary tract infection (UTI) is one of the commonest infections encountered by clinicians and despite the widespread availability of antimicrobial agents UTI has become difficult to treat because of appearance of pathogens with increasing resistance to antimicrobial agents. Objectives: The aim and objectives of this study were to determine the etiological Bacterial pathogens of the UTI and to determine the antibiotic sensitivity pattern of pathogens isolated. Methodology: The present study was a cross sectional study carried out in a private pathology laboratory situated in western Mumbai from January 2008 to December 2010. Total 280 urine samples were tested bacteriologically and for antibiotic susceptibility using standard procedures. Results: Out of 280 urine samples 168 (60%) patients tested positive for culture. E.coli was the most common isolate (44.96%) followed by Enterobacter spp (17.83%) and Klebsiella spp (14.72%) amongst the gram negative bacilli. Amongst the gram positive bacteria Staphylococcus aureus (92.3 %) was commonest. E. coli which was the main isolate identified was found to be highly susceptible to Amikacin (82.2%) followed by Ciprofloxacin (78.2%), Gentamicin (80.4%) ,Ampicillin (59%) and Nitrofurantoin (57%). Conclusion: This study finding showed that E. coli isolates were the predominant pathogens and showed increasing resistance pattern to the commonly prescribed drugs in private practise that in turn leaves the clinicians with very few alternative options of drugs for the treatment of UTIs.
Key Words:- Urinary Tract Infections, Antibiotic Susceptibility, Anti Microbial agents