DocumentsDate added
Research article:-Community medicine
*S.R.Nigudgi1, Boramma G2, Shrinivasreddy.B3,Kapate.R4
1,2 & 4 Professor, 3 Biostatistician, Department of Community Medicine, M R Medical College Gulbarga,India.
Abstract:- Nutritional status during school age is a major determinant of nutritional and health status in adult life. Health hazards associated with under nutrition and micro nutritional deficiencies remain major public health problems. Majority of the health problems affecting school children are preventable by promotion of hygienic practices. Objective:-To assess the nutritional status of school children, to find out the burden of specific deficiency disorders and to assess the status of personal hygiene among school children Study design:-Cross sectional study. Material Method: - the study was carried out in higher primary schools of Gulbarga city. Results: - Out of 935 school children under study 51.23% were boys and 48.77% were girls. 50.05% children were below average weight for age showing undernourishment. 22.35% children had specific deficiency diseases in which bitot’s spot in 48.80% children and anemia is 10.05%. 91.44% school children had good personal hygiene.
Key words:-Weight For Age, Anemia, Bitot’s spots, and Personal Hygiene.
Research article:-Biochemistry
1*Dr. Lokhande Suryabhan L, 2 Dr. Iyer Chandrashekhar M, 3 Dr. Shinde Ratnendra R, 4 Dr. Nandedkar Prerna D, 5 Dr. Kamble Mahendra T.
1*MD Biochemistry; Assistant professor, Department of Biochemistry Government Medical College Nagpur, India.
2MD Biochemistry; Professor, Department of Biochemistry,Government Medical College Nagpur, India.
3M.D. Preventive and Social Medicine; Professor and Head, Department of Preventive and Social Medicine, Seth G.S. Medical College and Hospital Mumbai, India.
4,5MD Biochemistry; Assistant professor, Department of Biochemistry Government Medical College Nagpur, India.
Abstract:- Background and Objectives: Type 2 Diabetes Mellitus (Type 2 DM) characterised by relative insulin deficiency or insulin resistance is associated with glucose intolerance, hypertension, a unique dyslipidemia, a procoagulant state, and an increase in macrovascular disease. The present study was conducted to assess the significance of Apolipoprotein B in cardiovascular diseases (CVD) and complications. Materials and Methods and Statistical Analysis: 50 diagnosed cases of type 2 DM in the age group 35-65 years were included in the study and 50 age and sex matched healthy controls were taken as controls. In both the groups, we have measured serum levels of traditional lipid parameters comprising of total cholesterol (TC), triglyceride (TG), HDL-C, low density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo-B) and waist-hip ratio (WHR) as cardiovascular risk factors. Statistical analysis was done by students unpaired‘t’-test and linear regression analysis and correlation. Results: The results of this study shows significant increased level of serum total cholesterol, TG, LDL-C and VLDL-C and Apo-B in type 2 DM patients as compared to controls (p<0.001). While Serum HDL-C level was significantly lower in type 2 DM patients as compared to controls (p<0.001). The waist hip ratio of Type 2 DM patients was found to be significantly higher as compared to controls. Conclusion: The findings of the present study indicated that apolipoprotein B (Apo-B) as a cardiovascular risk factors are significantly elevated in type 2 DM patients as compared to controls and apolipoprotein B (Apo-B) significantly elevated even if lipid profile parameters such as LDL-C and HDL-C were found to be normal, signifying routine estimation of apolipoprotein B (Apo-B), in addition to traditional lipid parameters in the cardiovascular risk assessment in Type 2 Diabetes Mellitus.
Key Words:- Type 2 Diabetes Mellitus (Type 2 DM), Apolipoprotein B (Apo-B), Traditional lipid parameters, Cardiovascular disease (CVD), Waist-hip ratio (WHR).
Research article:- ENT,
Minutha R1* and Sriram Nathan2.
*1MBBS, MS, Assistant Professor, 2MBBS, DLO, Dip N B (ENT), Senior Resident, Dept of ENT, Department of ENT, Madha Medical college, Chennai, India.
Abstract:- Background: unilateral acute conductive hearing loss is a unique entity in such that in most of the cases the diagnoses is confirmed and in a majority of cases is amenable to treatment. The common causes include traumatic perforation of the ear drum and otitis media with effusion. Other causes include unilateral Otosclerosis and traumatic dislocation of ossicles. Lesser common causes include post traumatic concussion and temporal bone fracture. The presentation is usually an acute (defined arbitrarily as less than three weeks) onset of hearing loss and confirmed by examination. The diagnostic work up includes audio logical evaluation and imaging studies such as HRCT (high resolution computerized tomography). The management is tailored to the cause and in most of the cases the recovery is satisfactory. Objective: To enumerate and evaluate two hundred cases of unilateral conductive hearing loss and to consider the management strategies.
Keywords:- Unilateral conductive hearing loss, pure tone audiometry.
Research article:-Medical biochemistry
* Nandedkar Prerna D.1, Kamble Mahendra T.2, Lokhande Suryabhan L.1, Vaidya Seema M.3, Chitta Shrinivas S.4
1M.B.B.S., M.D. (Biochemistry), Assistant professor (Biochemistry), Dept. of Biochemistry, Seth G.S. Medical college and hospital, Parel (E), Mumbai (M.S.),India.
2M.B.B.S., M.D. (Biochemistry), Assistant Professor, Dept. of Biochemistry, Govt. Medical College & Cancer Hospital, Aurangabad (M.S.),India.
3 M.Sc.(Biochemistry), PhD., Professor, Dept. of Biochemistry, Government Medical college, Latur, (M.S.),India.
4 M.B.B.S, M.D. (Physiology), Junior resident, Dept. of Physiology, Government Medical college, Nagpur, (M.S.), India.
Abstract:- Background: Patients with chronic kidney disease (CKD) have a higher prevalence of dyslipidemias than the general population. Almost all patients of CKD with nephrotic syndrome have an abnormal lipid profile and the cause of death in most of patients is cardiovascular complications. This dyslipidemia may be correlated with proteinuria. Therefore, it is important to screen all patients of CKD with nephrotic syndrome for dyslipidemia and find out its correlation with proteinuria. Aim:To estimate lipid profile and 24 hour urinary protein in patients of CKD with nephrotic syndrome. Settings and designs: This cross sectional study was undertaken in the Department of Biochemistry and Department of Medicine of Government Medical College and hospital Nagpur, Maharashtra. Material and method and statistical analysis: lipid profile and 24 hour urinary protein excretion were analyzed and compared between 50 age & sex matched CKD with nephrotic syndrome cases and CKD without nephrotic syndrome controls of age group 25‐60 years using unpaired two‐tailed Student‘t’ test. Results:Values of total cholesterol (p<0.001), triglyceride (p<0.001), LDL-C (p<0.001) and 24 hour proteinuria (p<0.001) were significantly higher in CKD with nephrotic syndrome compared to CKD without nephrotic syndrome but values of HDL-C (p<0.001) were significantly lower compared to CKD without nephrotic syndrome. Conclusion: Cardiovascular complications can be more frequent in patients of CKD with nephrotic syndrome and dyslipidemia correlates directly with severity of 24 hour proteinuria.
Keywords:- (CKD) chronic kidney disease, (NS) nephrotic syndrome, 24 hour proteinuria, Dyslipidemia,(CVD) cardiovascular disease.
Research article:-Medical microbiology
*Nayakanti Raghu Prakash Reddy1 , Animireddy Kishore2 , A.Franklin3, E.Prabhakar Reddy4 1Assistant Professor of Microbiology, 2Associate Professor of Microbiology,3Professor of Microbiology, 4Associate Professor of Biochemistry, Sri Lakshmi narayana Institute of Medical Sciences, Puducherry, India.
Abstract: Introduction: Viral hepatitis is the inflammation of the liver caused by hepatitis viruses. The most common causes of viral hepatitis are the five unrelated hepatotropic viruses Hepatitis A, Hepatitis B, Hepatitis C, Hepatitis D, and Hepatitis E. Zn is essential for normal development and function of cell mediating innate immunity, Selenium is an essential micronutrient for human health, Copper accumulation in fibrotic liver caused by chronic hepatitis may contribute to hepatic injury. Material and Methods: The study was conducted a total number of patients 15 from SLIMS Puducherry, 15 from Arogya diagnostic centre, tirupati, Andhra Pradesh. Collected samples was separated by centrifugation at 2000 rpm for 15 min. Separated samples carried out for assay ie, Zinc, copper, selenium by using standard commercial kits. Results and Discussion: We showed that elevated zinc levels in HBV patients correlate with low levels of AST and ALT. Our study showed that selenium, Zn levels were decreased in HBV Patients. We found serum Zn and selenium, copper levels were decreased comparing with control levels. Conclusion: Zinc and selenium might be considered as a marker of normal liver function. Dietary intake of selenium and Zn are necessary to reduce the liver damage in HBV patients.
Keywords:- Viral hepatitis, Innate immunity, Trace elements, Fibrotic liver.