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Research article:-periodontics
Rosaiah Kanaparthy1*,Aruna Kanaparthy2 and Kamala Devi3
1Professor & HOD, Department of periodontics,2Reader,Conservative Dentistry & Endodontics, Peoples Dental Academy, Bhopal-462037, Madhya Pradesh, India.
3Principal & HOD, Govt Dental college & Hospital, Department of Periodontics & Oral Implantology, Hyderabad-500001, Andhra Pradesh, India.
Abstract:- Purpose: The present study was envisaged to compare the efficacy of adjunctive use of Azithromycin with scaling and root planing (SRP) the adjunctive use Amoxicillin and SRP, and SRP alone in the treatment of chronic periodontitis. To correlate the use of N-Benzoyl DL-Arginine 2- Naphthylamide (BANA) hydrolysis test and percentage of spirochete count with the periodontal parameters before and after periodontal therapy Methods: 30 subjects with chronic periodontitis were randomly selected and divided into three groups as follows. Group I: Subjects treated with scaling and root planing (SRP) alone. Group II: Subjects treated with SRP and systemic administration of Amoxicillin (SRP + AMOX). Group III: Subjects treated with SRP and systemic administration of Azithromycin (SRP + AZM). Periodontal parameters comprising of plaque index, bleeding index, probing pocket depth, clinical attachment level and microbiological parameters comprising of spirochete count and BANA test scores were assessed at base line and six weeks after completion of periodontal therapy for subjects in all the three groups. Results: The reduction in post-treatment scores as compared to pre-treatment scores of plaque index, bleeding index, pocket depth, clinical attachment levels and spirochete count was highly significant in all the groups(p<0.01). Conclusions: BANA hydrolysis is a reliable marker of periodontal disease as it has proved to be a suitable test for detection of spirochetes. The judicious use of systemic antibiotics in the treatment of chronic periodontitis may provide an additional benefit in the clinical outcome compared to SRP alone.
Key Words:- Amoxicillin , Azithromycin, Chronic Periodontitis, N-Benzoyl DL-Arginine 2- Naphthylamide.
Research article:-Pathology
*1Manu Mathur and 2Rishi Diwan
1MD, Assistant professor ,2 MD, Associate professor, Department of Pathology, S.R.G. Hospital and Medical College, Jhalawar, Rajasthan, India.
Abstract:-Objective: To find out frequency and pattern of ABO and Rh blood group among voluntary donors. Material and Methods: Voluntary donors attending blood bank or blood donation camps organized by Medical College Jhalawar ,Rajasthan between April 2008 to March 2012 (4 years study). Total numbers of 4911 such donors were included in this study. The ABO and Rh grouping done, data were recorded on specially formed proforma, tabulated and analyzed. Results: The result shows ABO group pattern as O>B>A>AB. The same pattern seen in Rh positive male and females while in Rh negative females the pattern was B>O>A>AB. The O Negative blood group was 2.24% while AB negative was at lowest position (0.71%). Discussion and Conclusion: This study shows blood group O is more common in voluntary donors in this area(32.8%).These results are quite similar to the many other studies done at other parts of country. Everyone should have knowledge of their blood group. This will help to save life of patients when blood transfusion is an emergency.
Key words:-ABO blood group, Rhesus (Rh) blood group, voluntary donors, blood transfusion.
Original research article:- Medical Bochemistry
Kiran Chugh1, Sandeep Goyal2, Vijay shankar1,* Manjulata Kumawat1, S.N. Chugh2, Manjri Goyal2.
1Department of Biochemistry, Pt. B. D. Sharma University of Health Sciences, Rohtak, Haryana, India.
2Department of Medicine, Pt. B. D. Sharma University of Health Sciences, Rohtak, Haryana, India.
Abstract:- Background and Objectives: Metabolic syndrome is the name given to a syndrome that is seen more often in people who are overweight or obese, and who have specific conditions that increase the risk of heart disease, diabetes, stroke, and other health problems. Metabolic syndrome is diagnosed when three out of the following five risk factors are evident. Researchers have now found that even subtle changes in thyroid function increase the risk for metabolic syndrome. We evaluated the thyroid function tests in obesity to explore the possibility of thyroid receptor resistance. Methods: the study was a cross-sectional study. It included 50 obese subjects with Body Mass Index (BMI) > 30 kg/m2 as cases (group I) and 25 individuals with BMI < 25 kg/m2 as controls (group II). T3 (Triiodothyronin), T4 (Thyroxine), TSH (Thyroid stimulating hormone) levels were measured as indicator of thyroid functions. Blood sugar and serum Insulin levels were measured. To define insulin resistance, Homeostasis model for insulin resistance (HOMA IR) was calculated in both groups and the HOMA IR value obtained in group II individuals served as reference mark. Based on the HOMA IR, group I subjects were divided into insulin resistant (subgroup IA) and insulin nonresistant (subgroup IB) individuals. Thyroid function tests were compared in both subgroups. Results: T3 and T4 levels were comparable whereas there was significant difference in TSH levels in insulin resistant (subgroup IA) and insulin nonresistant (subgroup IB) individuals. Conclusion: Raised TSH in insulin resistant obese persons independent of lowered T3 and T4 suggest it to be a part of insulin resistant state in obesity.
Keywords:-Obesity, Body mass index (BMI), Thyroid function tests, Insulin resistance, Homeostasis model assessment for insulin resistance (HOMA IR), Thyroid receptor resistance.
Research article:-Clinical pharmacy
OMOLE, Moses Kayode Pharm. D1., ADEBAYO, Sheriff Olalekun M. Pharm2. ADISA, Rasaq M. Pharm1
1Department of Clinical Pharmacy and Pharmacy Administration, Faculty of Pharmacy, University of Ibadan, Nigeria.
2Pharmacy Departments, General Hospital Oyo, Oyo State, Nigeria.
Abstract:- This prospective study was carried out to determine factors that may affect medication adherence among people living with HIV/AIDS (PLWHA), and receiving treatment at antiretroviral clinic, University College Hospital, Ibadan, but who are affiliated to Non Governmental Organizations such as FAPHAC and PLAN, Nigeria. All consenting subjects from these two support groups were enrolled into the study but 305 PLWHA volunteered to participate throughout the three months period of the study. The study was conducted with the aid of structured interview assisted questionnaires to obtain information on demographic characteristics, as well as availability and side effects of antiretroviral drugs. Descriptive and Chi-square statistical tests were used to evaluate the level of association between the variables being considered and respondent’s adherence to antiretroviral medications. Majority of people (80.3%) living with HIV/AIDS interviewed were females while (19.7%) were males. Male respondents (91.7%) showed better adherence to ARV medications than female counterparts (83.7%). Subjects in the age groups 24-35 years (59.1%) which is the most sexually active groups were more vulnerable when compared to other age groups. There was no significant relationship between medication adherence and age, sex, education, occupation and financial status (p>0.05), but there was a significant difference (P<0.05) between marital status of PLWHA and level of adherence to antiretroviral medications. There is need to carry out further study in order to fully explore the extent to which marital status and other factors can affect medication adherence of people living with HIV/AIDS.
Key Words:-Antiretroviral (ARV) Medication adherence, variables, Nongovernmental organization (NGO), Human-immunodeficiency-virus (HIV), Acquired immune deficiency syndrome (AIDS).
Research article:-
*Mendonca Reuben Lawrence MBBS1, Dev Nischay U. MBBS2, D’Souza Neevan D.R., MSc3, Akshay K.M., MD3 Shantaram Manjula, PhD4
*1Dept. of Pulmonology, Yenepoya Medical College, Yenepoya University, Mangalore 575 018, Karnataka, India. 2Daradahalli PHC, Mudigere Taluk, Chikmagalur District, Karnataka, India. 3Dept. of Community Medicine, Yenepoya Medical College, Yenepoya University, Mangalore 575 018, Karnataka, India. 4Dept. of Biochemistry, Yenepoya Medical College, Yenepoya University, Mangalore 575 018, Karnataka, India.
Abstract:- An attempt was made to focus on rural adolescents since majority of the Indian population lives in villages. We tried to observe male and female adolescents and their physical appearance in terms of height, weight, body mass index (BMI), life style factors such as intake of total proteins, total calories, their physical activities at school, time spent in reading, sleeping and watching television programs. This study was carried out over a period of four months on school children from the villages of Chikmagalur district of Karnataka state, India. There was no statistical significance between gender in 8th, 9th and 10th standards. Reading habits of the adolescents have significant increase as they grew older. As the walking hours of adolescents were increased, reading hours and exercises were decreased though not significantly. As age of the high school students was increased, sleeping hours were decreased; showing moderate inverse co-relation with statistical significance.
Key words:- Adolescents, family, lifestyle, rural area.