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Case Report:-Anesthesiology
Alper Yosunkaya, Prof, MD; Şule Arıcan, MD; Hale Borazan, Assistant Prof, MD; Tuba Berra Sarıtaş, Assistant Prof, MD; Betül Olcay, MD.
Necmettin Erbakan University, Meram Medical Faculty, Department of Anesthesiology and Reanimation, Konya, Turkey.
Abstract:-Acute isoniazid intoxication is relatively uncommon but potentially life-threateningcondition in which the anesthesiologists may become involved when respiratory deficiency and refractory seizures could be accompanied with metabolic acidosis. In this report, we describe the management of such a case of INH intoxication in a suicide attempt; we also discuss the specific antidote, pyridoxine, route we have to use and other accompanied adjuncts for the treatment in the light of the literatures.
Key Words:-Isoniasid intoxication, pyridoxine, seizure, benzodiazepine
Research article:-Physiotherapy
Sethi Vanshika1* and Pragyadeep2
1Phd. Physiotherapy, Section in-charge physiotherapy department, 2Student BPT 4th year, Saaii College of medical science and technology, Kanpur,India.
Abstract:- Introduction: Chronic pain is that pain which lasts for more than three months. Depression is the most common emotion associated with chronic low back pain. The type of depression that often accompanies chronic low back pain is referred to as major depression or clinical depression. Methodology: A sample of 30 chronic low back pain patient of 20 to 40 year of age were taken by convenient sample method.pre treatment assessment of depression, anxiety and stress status on DASS scale were taken. Patients were given core stability training session of 4 week which included bridging, curl up exercises, pelvic bridging exercises, spinal extension exercise and side bridging exercises. These training treatment duration was of 30 min with 10 repetition for 4 weeks including 6 days a week for each exercises.post treatment assessment were done by using same outcome measures. Results: DASS(Depression, anxiety ,stress scale) score before giving the treatment were as 18.83±5.12, 11.06 ± 2.9 ,17.5 ± 3.7, whereas the score after exercises were as 16.6±4.30, 9.7 ± 2.6, 15.9 ± 3.3 with t-value of 6.299, 5.25, 3.1 with p-value of 0.000* , 0.000* ,0.004* ,which shows significant difference in scores. Conclusion: Exercise programs can be carried out safely in patient with chronic low back pain and there by their level of depression, anxiety and stress can be decreased by short duration core stability exercises as it is economical in time and money.
Key Words:- Core stability exercises, depression, anxiety, stress, low back pain.
Research article:-Biology
1Vahid Yousefi Babadi, *2Leila Najafi , 3Azadeh Najafi, 4Hosein Gholami, 5Mohammad Ebrahim Beigi Zarji, 6Jalal Golzadeh, ,7Esmaiel Amraie,8Ali Shirband.
1,5,7,8M.A.in Biology,Payam-e-Noor University of Tehran,Tehran,Iran.
2Ph.D.Candidate in Health Care Services Administration, Shahid Beheshti University of Medical Sciences,Tehran,Iran.
3M.A. in Sociology,Research and sciences Branch Islamic Azad University,Tehran,Iran. 4G.P.Shahid Beheshti University of Medical Sciences,Tehran,Iran.
6M.A.in Biology,Uromieh University,Uromieh,Iran..
Abstract:- Background: Iron oxide nanoparticles can be used for medical imaging,disease diagnosis,drug delivery,cancer treatment,gene therapy and other cases.These particles accumulate in liver cells and lead to oxidative stress with generation of reactive oxygen species. Objectives: This study investigates the effect of iron oxide nanoparticles on liver tissue and enzymes[alanine aminotransfere(ALT),aspartate aminotransferase(AST)and alkaline phosphatase(ALP)]in male rat. Materials and methods: 40 adult male rats of wistar strain, weighing 250-300g were used for this study.The ratswere randomly assigned to four groups.One group was control and other three groups were fed with iron oxide nanoparticles at 20, 50 and 150 µg/kg concentrations respectively for 15 days. Venous blood was taken to measure liver enzymes at the end of treatment. Liver of rats removed for histological experiments. Results: Significantly enhanced (P<0.05) AST level obtained as well as ALT and ALP level with used of maximum concentration of iron oxide nanoparticles (150 µg/kg) as compared to normal group. Conclusion: Based on our result, using high concentration of iron oxide nanoparticles could be caused undesirable effects on liver with damage to hepatocyte and level elevation of liver enzymes.
Key words:- Hepatocyte, Nanoparticle, Enzyme, Iron oxide.
Research article:-Ophthalmology.
Pujar Chaitra. DOMS DNB OPHTH 1*, M Jayashree P. DOMS DNB OPHTH 2, Patil Madhuri G. MBBS 3 and Santosh. MBBS3.
1*Senior Resident,2Associate Professor,3Junior Resident, Department of Ophthalmology, S N Medical College Bagalkot-587102, Karnataka,India.
Abstract:- Purpose- To assess the awareness of glaucoma among the urban population of Bagalkot district in north Karnataka,India.
Material and Methods:- A total of 100 subjects, >20 yrs old, among the urban population of Vidyagiri and Navanagar areas in Bagalkot, in North Karnataka were enrolled into the study. The responses of the subjects (N=100) who completed a structured questionnaire regarding the awareness (heard of glaucoma) and knowledge (understanding glaucoma) of glaucoma, formed the basis of this study.
Results:- Awareness of glaucoma was (n=35, 35 %) was good in Vidyagiri and Navanagar areas of Bagalkot. No significant difference was noted between the different age-groups (p=0.06687) and between the males and females (p=0.392).Awareness of glaucoma was significantly higher in literates (p= 0.0042) and in higher socioeconomic group (p=0.005154).A total of 14 subjects (n=14, 40 %) knew that the visual loss due to glaucoma was permanent. The main source of awareness of glaucoma in this population was TV/Magazines/media 17(48.57%), Ophthalmologist 7 (20.38%),family members and friends 5(14.28%),Doctor 4(11.42%), and Optician-1(1.28%),followed by eye camp 1(1.28%). Conclusion:- Awareness of glaucoma was comparatively higher among the urban population of Vidyagiri and Navanagar areas of Bagalkot District, in North Karnataka. Compared to the previous studies the awareness is better, due to increased exposure to Mass Medias like Television, Radio Magazines and so on. Improvement in the health care services over the years, do contribute to the increased awareness about glaucoma. Community based health education programmes go a long way in increasing the level of awareness and knowledge about glaucoma.
Keywords:- Glaucoma prevalence, awareness, and population based epidemiological study.
Research article:-Pathology
Khanna Vinay1*, Bairy Indira2 , Maradi Ravindra3, Khanna Ruchee4, Vishwanath Shashidhar5, Sathyanarayanachar Manjunath6
1Assistant Professor, 2Professor, 5Associate Professor, Department of Microbiology, 3Associate Professor, Department of Biochemistry, 4Associate Professor, Department of Pathology, 6Associate Professor, Department of Forensic Medicine, Kasturba Medical College, Manipal, Manipal University.
Abstract:- Recent HIV infection (<6 months) represents the initial stage of the disease, when viral replication is associated with dissemination in lymphoid tissue and a distinct immunologic response. Patients with recent infection have symptoms, including flu like symptoms, fever, skin rash, headache, diarrhea, malaise, and lethargy. Recent HIV infections also include seroconversion with positive HIV serology generally takes place at 3 to 12 weeks following the viral transmission and clinical latent period which extends beyond 6 months in which most of the patients remained asymptomatic. In this study Established HIV-1 infection (>6 months) includes clinical latent period, symptomatic HIV-1 infection, AIDS and advanced HIV-1 infection, characterized by a CD4 cell count <50/mm3. This study was conducted in 261 HIV seropositive patients with recent and established HIV-1 infection. Data analyzed using SPSS 16.0 and variables are compared by using chi square test. There were total 33 cases identified as recent cases and 228 cases as established cases. Among recent and established infection fever was the commonest presentation. Flu like symptoms were commonly seen in all cases of recent infection. Majority of established cases of HIV showed generalized lymphadenopathy with weight loss.
Key words:-Human Immune deficiency Virus, Detuned ELISA, CD4 cells, AIDS.