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Original article:-Anesthesiology
1Banu Baran, MD , *2Tuba Berra Saritas, MD , 3Cigdem Sizer, MD , 4Hale Borazan , MD , 5Gamze Sarkılar, MD , 6Seref Otelcioglu, MD.
1Banu Baran , MD, Sarayönü Government Hospital, Anesthesiology And Reanimation DPT, Konya, Turkey.
*2Tuba Berra Saritas, MD, Assistant Prof. , Necmettin Erbakan Uni. Meram Medical School, Anesthesiology And Reanimation DPT. Konya, Turkey.
3Cigdem Sizer , MD, Konya Government Hospital, Anesthesiology And Reanimation DPT Konya, Turkey.
4Hale Borazan, MD,Assistant Prof.,Necmettin Erbakan Uni. Meram Medical School Anesthesiology And Reanimation DPT. Konya, Turkey.
5Gamze Sarkılar, MD, Assistant Prof . , Necmettin Erbakan Uni. Meram Medical School Anesthesiology And Reanimation DPT Konya, Turkey.
6Şeref Otelcioğlu, MD, Prof. Dr. Necmettin Erbakan Uni. Meram Medical School Anesthesiology And Reanimation DPT Konya, Turkey.
Abstract:- Background & objectives: It is aimed to evaluate the effect of intraarticular levobupivacaine and sufentanil on postoperative pain and tramadol consumption in arthroscopic knee surgeries. Methods: The patients were and divided into three groups randomly. 10 mg levobupivacaine to Group I, 10 mg levobupivacaine with 10 mcg sufentanil to Group II and saline to Group III in equal volumes was applied before tournement deflation intraarticularly. VAS, sedation scores, tramadol consumption at 1, 2, 3, 6, 12, and 24 hours, side effects and additional analgesic requirements reported. Results: Demographics, sedation scores, additional analgesic need and haemodynamics weren't statistically different (p>0,05). VAS scores of rest and movement were statistically significant between Group I -III and Group II-III at 1, 2, 3, 6, 12.and 24 hours (p<0,05). Group I and II VAS scores were approximate but not statistically significant at rest (p>0,05) 1. and 2. hours VAS scores at movement was statistically significant (p<0,05). Postoperative tramadol consumption of Group I postoperative 1,2,3 and 6 hours results were lower than Group III(p<0,05). There was no statistically significance between all of the groups at postoperative 12 and 24 hours (p>0,05). Interpretation & Conclusions: It's thought that intraarticular levobupivacaine and sufentanil + levobupivacaine provided effective postoperative analgesia in arthroscopic knee surgery however sufentanil addition to levobupivacaine provided better pain control at early postoperative hours and reduce additional analgesic consumption.
Keywords:-Arthroscopy,Sufentanil,Tramadol,Pain.
Case Report:-Anesthesiology
Alper Yosunkaya, Prof, MD; Şule Arıcan, MD; Hale Borazan, Assistant Prof, MD; Tuba Berra Sarıtaş, Assistant Prof, MD; Betül Olcay, MD.
Necmettin Erbakan University, Meram Medical Faculty, Department of Anesthesiology and Reanimation, Konya, Turkey.
Abstract:-Acute isoniazid intoxication is relatively uncommon but potentially life-threateningcondition in which the anesthesiologists may become involved when respiratory deficiency and refractory seizures could be accompanied with metabolic acidosis. In this report, we describe the management of such a case of INH intoxication in a suicide attempt; we also discuss the specific antidote, pyridoxine, route we have to use and other accompanied adjuncts for the treatment in the light of the literatures.
Key Words:-Isoniasid intoxication, pyridoxine, seizure, benzodiazepine
Research article:-Community Medicine.
1*Gupta Sanjay Kumar MD, 2Varshney Atul MS, 3J. Thomas Mathew MD, DM,4 Gaur Neeraj ,5Anil J. Purty MD, DNB, 6Joy Bazroy MD
1*Associate Professor, 4Assistant Professor, Department of Community Medicine, 2Associate Professor Orthopedics, Peoples college of Medical sciences and Research Bhopal-India. 3Associate Professor, Department of Nephrology, 5Professor, 6Associate Professor ,Department of Community Medicine Pondicherry Institute of Medical Sciences (PIMS) Kalapet Pondicherry-14,India.
Abstract:- Introduction:-About 5% of all hospital admission in the USA are kidney problems related and this problem is comparatively higher in India. A relatively higher proportion of cases are either missed or present late with complication, in children 4% of cases were due to acute post streptococcal glomerulonephritis. Objective:-To estimate the prevalence of renal diseases in the rural community. Methodology:-To study the prevalence of renal diseases in the rural community of Pondicherry. We were selected the rural area having a population of 13,256 under the Primary Health Centre (PHC, Katterikuppam). Result:–Of the 1140 individuals studied, the majority were found to be in the age group of 15-35 (51.5 percent). Two thirds of the individuals surveyed were females (65.6 percent). A family history of kidney disease was present only in 3.7 percent of cases. The most common symptom was dysuria (5.26 percent) followed by oedema (3.77 percent).4.71percent of individuals were found to have swelling of feet and 0.8 percent swelling of the face.23.34 percent of the people were found to have hypertension, 6.75 percent positive for urine sugar and 3.24 percent for urine albumin, 96.6 percent of them had no significant past history. Two ages peak were found regarding renal disease in study area, one between 25 – 35 years of age and second 56 years & above, significant correlation were found in hypertension & Proteinuria, renal diseases were significantly higher in diabetes mellitus group. Conclusion:-Of the 1140 individuals studied, the majority were found to be in the age group of 15-35 (51.5 percent), two thirds of the individuals surveyed were females (65.6 percent). Two ages peak were found regarding renal disease in study area, one between 25 – 35 years of age and second 56 years & above. Significant correlation were found in hypertension & proteinuria, renal diseases were significantly higher in diabetes mellitus group.
Key Words:- Renal disease, rural area, hypertension &glycosuria, family history.
Research article:-Biology
1Vahid Yousefi Babadi, *2Leila Najafi , 3Azadeh Najafi, 4Hosein Gholami, 5Mohammad Ebrahim Beigi Zarji, 6Jalal Golzadeh, ,7Esmaiel Amraie,8Ali Shirband.
1,5,7,8M.A.in Biology,Payam-e-Noor University of Tehran,Tehran,Iran.
2Ph.D.Candidate in Health Care Services Administration, Shahid Beheshti University of Medical Sciences,Tehran,Iran.
3M.A. in Sociology,Research and sciences Branch Islamic Azad University,Tehran,Iran. 4G.P.Shahid Beheshti University of Medical Sciences,Tehran,Iran.
6M.A.in Biology,Uromieh University,Uromieh,Iran..
Abstract:- Background: Iron oxide nanoparticles can be used for medical imaging,disease diagnosis,drug delivery,cancer treatment,gene therapy and other cases.These particles accumulate in liver cells and lead to oxidative stress with generation of reactive oxygen species. Objectives: This study investigates the effect of iron oxide nanoparticles on liver tissue and enzymes[alanine aminotransfere(ALT),aspartate aminotransferase(AST)and alkaline phosphatase(ALP)]in male rat. Materials and methods: 40 adult male rats of wistar strain, weighing 250-300g were used for this study.The ratswere randomly assigned to four groups.One group was control and other three groups were fed with iron oxide nanoparticles at 20, 50 and 150 µg/kg concentrations respectively for 15 days. Venous blood was taken to measure liver enzymes at the end of treatment. Liver of rats removed for histological experiments. Results: Significantly enhanced (P<0.05) AST level obtained as well as ALT and ALP level with used of maximum concentration of iron oxide nanoparticles (150 µg/kg) as compared to normal group. Conclusion: Based on our result, using high concentration of iron oxide nanoparticles could be caused undesirable effects on liver with damage to hepatocyte and level elevation of liver enzymes.
Key words:- Hepatocyte, Nanoparticle, Enzyme, Iron oxide.
Research article:-Ophthalmology.
Pujar Chaitra. DOMS DNB OPHTH 1*, M Jayashree P. DOMS DNB OPHTH 2, Patil Madhuri G. MBBS 3 and Santosh. MBBS3.
1*Senior Resident,2Associate Professor,3Junior Resident, Department of Ophthalmology, S N Medical College Bagalkot-587102, Karnataka,India.
Abstract:- Purpose- To assess the awareness of glaucoma among the urban population of Bagalkot district in north Karnataka,India.
Material and Methods:- A total of 100 subjects, >20 yrs old, among the urban population of Vidyagiri and Navanagar areas in Bagalkot, in North Karnataka were enrolled into the study. The responses of the subjects (N=100) who completed a structured questionnaire regarding the awareness (heard of glaucoma) and knowledge (understanding glaucoma) of glaucoma, formed the basis of this study.
Results:- Awareness of glaucoma was (n=35, 35 %) was good in Vidyagiri and Navanagar areas of Bagalkot. No significant difference was noted between the different age-groups (p=0.06687) and between the males and females (p=0.392).Awareness of glaucoma was significantly higher in literates (p= 0.0042) and in higher socioeconomic group (p=0.005154).A total of 14 subjects (n=14, 40 %) knew that the visual loss due to glaucoma was permanent. The main source of awareness of glaucoma in this population was TV/Magazines/media 17(48.57%), Ophthalmologist 7 (20.38%),family members and friends 5(14.28%),Doctor 4(11.42%), and Optician-1(1.28%),followed by eye camp 1(1.28%). Conclusion:- Awareness of glaucoma was comparatively higher among the urban population of Vidyagiri and Navanagar areas of Bagalkot District, in North Karnataka. Compared to the previous studies the awareness is better, due to increased exposure to Mass Medias like Television, Radio Magazines and so on. Improvement in the health care services over the years, do contribute to the increased awareness about glaucoma. Community based health education programmes go a long way in increasing the level of awareness and knowledge about glaucoma.
Keywords:- Glaucoma prevalence, awareness, and population based epidemiological study.