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Research article:-Midwifery and Immunology
Direkvand-Moghadam A (MSc) 1 and Khosravi A (MSc, PhD) 2*
1 Department of Midwifery, 2Department of Immunology, Ilam University of Medical Sciences, Ilam, Iran.
Abstract:- Modern pharmacological therapies for menstruation pain commonly focus on alleviating menstrual pain and relaxing uterine muscle contraction by using non-steroidal anti-inflammatory drugs (NSAIDs), or oral contraceptive pills. Because treatment with NSAIDs is associated with a number of side effects and inadequate pain control by NSAIDs alone in some of cases, the current study was designed to overcome such limitation using Shirazi Thymus Vulgaris as a new pain killer. 120 students of Ilam University of Medical Sciences checked for their inclusion criteria that were singleness at the time of study, aged between 18 to 25 years, accommodated at University campus and having primary dysmenorrhea prior to the enrolment to the study. The participants either received Shirazi Thymus Vulgaris (5ml of the four times a day) or Ibuprofen (three times a day) orally. Both the analyzing methods of VMS and VAS were used to record the pain grade and pain scoring among the participants. The Shirazi Thymus Volgaris cured the pain with similar grade and score as the Ibuprofen at the first and second month of trial. The pain killing specificity of the current herbal medication may be due to its antispasmodic effects and therefore such safe medication can be evaluated and used for the pain therapy using different pain scoring system.
Keywords: -Menstrual pain, Pain Score, Shirazi Thymus Vulgaris, VMS.
Corresponding Author:
Khosravi A ., Department of Immunology, Ilam University of Medical Sciences, Ilam, Iran.
Research article:-Cardiology
Dr.T.Rajini Samuel*
Cardiology Department, Venkataeswara Hospitals, 36-A Chamiers road, Nandanam, Chennai, India.
*Presently doing M.D. Biochemistry in Sree Balaji Medical College and Hospital, Chromepet, Chennai. India.
Abstract:- Aims: To make people understand what Einthoven was really talking about.
Methods and results: In the hex axial reference system of ecg, plot the net voltages of bipolar limb leads and connect them. Similarly, plot the net voltages of unipolar limb leads and connect them. Each forms equilateral triangles. Convert the equilateral triangles into circles. Each circle have same origin, same orientation, but different radii because the bipolar and unipolar limb leads have different resistance. The ratio of their resistance is 4/3. Hence the ratio of the area of the two circles is always constant and equal to 4/3. The square root of 4/3 is 1.154. The ratio of their radii is 1.154 .Multiply each unipolar limb lead voltages by 1.154 and then plot. The two equilateral triangles are on the same circle. The correction factor 1.154 is used because bipolar and unipolar limb leads have different resistance and the ratio of their resistance is 4/3. Thus heart is situated in the centre of the electric field which it generates. The two upper limbs and the left lower limb are the extensions of its electrical field. Voltage recorded in a particular lead is the result of dot product between the lead vector (measured in metre) and the cardiac vector measured in volt/metre. Hence voltage is a scalar quantity. The angle (α) determination from the ecg:
Tan α= (1.154*avF)/ Lead 1
Conclusion: Einthoven triangle is an absolute electrical equilateral triangle. Each cardiac wave can be represented in the form of circles.
Keywords:-Cardiac vector, Shifted Einthoven triangle.
Research article:-Quality assurance
1Swapnil W. Tekade, 1Shweta S. Havele, 2*Sunil R. Dhaneshwar.
1Department of Quality Assurance, Bharati Vidyapeeth University, Poona College of Pharmacy, Erandwane, Pune – 411038, Maharashtra, India.
2Department of Pharmaceutical Chemistry, RAK Medical & Health Sciences University College of Pharmaceutical Sciences Ras Al Khaimah Post Box No 11172, U.A.E.
Abstract:- This paper describes a new, simple, precise, and accurate HPTLC method for simultaneous estimation of etodolac and thiocolchicoside as the bulk drug and in tablet dosage form. Chromatographic separation of the drugs was performed on aluminum plates precoated with silica gel 60 F254 as the stationary phase and the solvent system consisted of chloroform : methanol : toluene (6 : 2 : 3 v/v/v/v). Densitometric evaluation of the separated zones was performed at 238 nm. The two drugs were satisfactorily resolved with RF values of 0.20 and 0.50 for thiocolchicoside and etodolac, respectively.
Key Words:- Etodolac, thiocolchicoside,HPTLC.
An Over view
DV Muralidhara1, Krithika D Muralidhara2*
1PhD, (Professor of Physiology), Faculty of Medicine and Health Sciences, University Sultan Zainal Abidin, Kuala Terengganu, Malaysia. 2*MBBS, MD, (Senior Registrar), Fr Muller Medical College, Mangalore, India.
Abstract:- A child is born with incompletely developed organ systems of the body that may not be functionally mature. One of the most important functions that would be compromised is body temperature regulation, particularly so in the premature babies. This may be very crucial as babies have to adapt from a warm temperature to low ambient temperatures immediately after birth. Many clinical studies that have reported thermoregulatory deficiencies in premature babies support such views. There are many factors involved in thermoregulation. However, nature has provided a natural thermoregulatory system in the form of brown adipose tissue (BAT), especially in the infants that plays a vital role. BAT has also gained a lot importance in energy regulation in humans. An overview of the role of BAT in infants is presented in this article.
Keywords:-Brown adipose tissue, thermoregulation, infants.
Research article:-Biology
1Vahid Yousefi Babadi, *2Leila Najafi , 3Azadeh Najafi, 4Hosein Gholami, 5Mohammad Ebrahim Beigi Zarji, 6Jalal Golzadeh, ,7Esmaiel Amraie,8Ali Shirband.
1,5,7,8M.A.in Biology,Payam-e-Noor University of Tehran,Tehran,Iran.
2Ph.D.Candidate in Health Care Services Administration, Shahid Beheshti University of Medical Sciences,Tehran,Iran.
3M.A. in Sociology,Research and sciences Branch Islamic Azad University,Tehran,Iran. 4G.P.Shahid Beheshti University of Medical Sciences,Tehran,Iran.
6M.A.in Biology,Uromieh University,Uromieh,Iran..
Abstract:- Background: Iron oxide nanoparticles can be used for medical imaging,disease diagnosis,drug delivery,cancer treatment,gene therapy and other cases.These particles accumulate in liver cells and lead to oxidative stress with generation of reactive oxygen species. Objectives: This study investigates the effect of iron oxide nanoparticles on liver tissue and enzymes[alanine aminotransfere(ALT),aspartate aminotransferase(AST)and alkaline phosphatase(ALP)]in male rat. Materials and methods: 40 adult male rats of wistar strain, weighing 250-300g were used for this study.The ratswere randomly assigned to four groups.One group was control and other three groups were fed with iron oxide nanoparticles at 20, 50 and 150 µg/kg concentrations respectively for 15 days. Venous blood was taken to measure liver enzymes at the end of treatment. Liver of rats removed for histological experiments. Results: Significantly enhanced (P<0.05) AST level obtained as well as ALT and ALP level with used of maximum concentration of iron oxide nanoparticles (150 µg/kg) as compared to normal group. Conclusion: Based on our result, using high concentration of iron oxide nanoparticles could be caused undesirable effects on liver with damage to hepatocyte and level elevation of liver enzymes.
Key words:- Hepatocyte, Nanoparticle, Enzyme, Iron oxide.