DocumentsDate added
Case report:-
Kunwarjeet Singh1, Himanshu Aeran2, Narendra Kumar3 and Nidhi gupta4
1Reader, Department of Prosthodontics and implantology, 3 Professor, Department of Prosthodontics and implantology,4 Reader, Department of Pedodontics and Preventive DentistryInstitute of Dental Studies and Technologies, Modinagar, Ghaziabad, Uttar Pradesh, Indai.
2Professor,Department of Prosthodontics and implantology,Seema dental college,Rishi Kesh, uttar Pradesh, India.
Abstract:- Aims and objectives: Making of definitive/secondary impression of displaceable flabby tissues with minimum or no displacement of tissue by using window impression technique. Background: Displaceable, flabby or hyperplastic tissues or commonly seen in the anterior region of edentulous maxilla opposing mandibular anterior natural teeth or in the mandibular alveolar ridge when extensive bone resorption has occurred. Prevalence of flabby ridges can vary, occurring in up to 24% of edentulous maxilla and in 5% of edentulous mandible. Displacement of flabby tissues during impression making is always a concern. Soft tissues that are displaced during impression making tend to return to their original form, and complete dentures fabricated from such impression will not accurately fit on the recovered tissues resulting in loss of retention, stability and occlusal disharmony the dentures. Materials and Methods: This technique uses a custom tray with a window over mobile tissues and a mucostatic impression material to minimize distortion of tissues while making impression. First an accurate record of the denture supporting and limiting structure is made except for the mobile tissues which are recorded in second step using light body polyvinyl siloxane impression material in the window area of special tray. Conclusion: The use of this technique helps in maintaining the contour and recording the detail of the tissues without displacing the flabby tissues. Hence it improves the prognosis for complete denture without surgical removal of hyperplastic tissues.
Key words:- Window impression technique, flabby ridge, polyvinyl siloxane, hypermobile tissues, Mucostatic, light body.
Research article:-Microbiology
Bineeta Kashyap1*,Rajat Jhamb2,Prakash Kumar Mishra3,Iqbal R Kaur4.
1MBBS MD, Assistant Professor,3MBBS,Post Graduate Student,4MBBS MD, Professor & HOD, Department of Microbiology,2MBBS MD,Department of Medicine, UCMS & GTB Hospital, New Delhi, India.
Abstract:- Background and objectives: Diagnostic options for pulmonary tuberculosis in resource-poor settings are commonly limited to smear microscopy. Direct smear microscopy is inexpensive, rapid, and highly specific in settings where tuberculosis is endemic. However, direct smear microscopy has poor sensitivity (range, 20 to 80%), particularly in HIV-coinfected patients. The Stop TB Partnership Retooling Task Force identified bleach sedimentation as one of the promising approaches to improving the sensitivity of sputum smear microscopy in high-burden countries. Hence this study was initiated to see the effect of bleach optimization on sputum samples for direct microscopic diagnosis of pulmonary tuberculosis. Method: A prospective study was done from February 2011 to March 2011 at the Department of Microbiology, U.C.M.S & G.T.B hospital, Delhi. Sputum sample received were aliquoted. Smears prepared from the first aliquots were stained with Ziehl-Neelsen (ZN) stain after petroff’s concentration and cultured on LJ medium. The second aliquots of sputum sample were treated with bleach and processed with centrifugation and sedimentation techniques. Smears were stained with ZN and viewed under direct microscopy. Result: Out of 50 samples received, 4 samples (8%) were positive for AFB by ZN staining after petroff’s concentration, bleach centrifugation and bleach sedimentation techniques. All these samples were also culture positive on LJ medium. Conclusion: Bleach treatment (centrifugation and sedimentation) of sputum correlates with but does not improve the sensitivity of smear microscopy over ZN staining after petroffs concentration for the diagnosis of TB in a high TB burden area. Further evaluation of this method as a tool for tuberculosis control with more focus on alternative approaches to optimizing smear microscopy strategies is needed.
Key words:- Sputum microscopy, pulmonary tuberculosis, bleaches optimization, sedimentation, centrifugation.
Review Article:-
Nidhi Gupta1* and Kunwarjeet Singh2
1Reader, Department of Pedodontics and Preventive Dentistry, 2Reader, Department of Prosthodontics and implantology, Institute of Dental Studies and Technologies, Modinagar, Ghaziabad, Uttar Pradesh, India.
Abstract:- In the last decade, there has been a huge explosion of interest in technologies involving remineralization of enamel and dentin. Remineralization is the natural process for non-cavited lesions and relies on calcium and phosphate ions assisted by fluoride to rebuild a surface on existing crystals remnants in subsurface lesions remaining after demineralization. These remineralized crystals are less acid soluble than the original mineral. However, when the bacterial challenge is high or the salivary components are lacking, remineralization is insufficient to halt or reverse the caries process. There is need to find ways to enhance the remineralization process and to transfer such knowledge into clinical therapy. The purpose of this present article is to demystify some of the current products and therapies available for remineralization.
Key words:- Remineralization, Recaldent, casein, phosphopeptide, Bioglass, Beta calcium phosphate.
Original article:-Community Medicine
Rituja Kaushal1, Neeraj Gour2*,Sanjay Kumar Gupta3, Arvind V Athawale4,M S Pathak5, P Tripathi6 and K Kaushal7.
1Post Graduate Resident,2Assistant Professor,3Associate Professor,4Professor and Head,5Associate Professor ,Department of Community Medicine, Peoples College of Medical Sciences & Research Centre Bhopal, M.P ,India.
6District Malaria Officer,Bhopal,M.P,India.
7Ex Superintendent,PMC, Bhopal,M.P ,India.
Abstract:- After years of fight against Malaria-a major public health problem, various states of India have started achieving success in controlling & preventing malaria transmission by implementing a broader mix of interventions. This observational secondary data based study was undertaken to assess the success achieved by District Malaria Centre, Bhopal in terms of various epidemiological surveillance parameters like API,ABER,SPR,SFR, Pf% etc. Overall a declining trend was found more or less among all epidemiological parameters which itself somehow by far reflect the quality of efforts put by district health officials and health workers. This study also demands a multicentre qualitative research in this aspect to explore what efforts and reasons have been responsible for this decline in various malariomatric parameters.
Key words:- Bhopal; malariomatric parameters; trend.
Original article:- Pharmacology and Therapeutics
Frans D Suyatna MD PhD and Effi Setiawati MSc Pharm. Department of Pharmacology and Therapeutics, Medical School, University of Indonesia, Salemba 6, Jakarta 10430, Indonesia.
Abstract:- Dehydroepiandrosterone (DHEA), a precursor of steroidal hormones, has been widely available as food supplement. Consumption of it, especially in the long term, may alter endogenous hormone composition in man. In the present study we investigated the effects of 50 mg DHEA orally administered in 5 consecutive days, in 13 healthy male subjects of 20-30 years old on steroidal hormone metabolites in urine. Urine samples were collected at zero time, 1, 2, 4, 5, 7, 8, 10, 12, 14 and 24 hours on day 5 after DHEA consumption and the metabolites were measured as ratios. Our results showed that the T/EpiT ratios were 1.07 ± 1.15 at zero time, peaked at 8 hours (1.18 ± 1.21), before and 1.03 ± 1.15 at zero time, peaked at 8 hours (2.11 ± 2.53) after exogenous DHEA. The A/Etio ratios were 1.45 ± 0.54 at zero time, peaked at 12 hours (1.82 ± 0.68), before and 0.77 ± 0.49 at zero time, peaked at 4 hours (1.51 ± 0.67) after exogenous DHEA. The ratios of glucuronate metabolites of 5α-androstane-3α, 17β-diol/5β-androstane-3α, 17β-diol(5α-diol/5β-diol) were 0.56 ± 0.29 at zero time, peaked at 8 hours (0.68 ± 0.40), before and 0.53 ± 0.38 at zero time, peaked at 8 hours (0.63 ±0.53), after exogenous DHEA. The DHEAS/DHEA glucuronate ratios were 20.88 ± 18.82 at zero time, peaked at 4 hours (25.60 ± 25.17), before and 67.76 ± 46.65 at zero time, peaked at 8 hours (158.03 ± 95.63), after exogenous DHEA. The DHEA levels were 30.1 ± 12.9 ng/ml at zero time and slightly fluctuated with the lowest value at 8 hours (18.99 ± 9.9) ng/ml, before and 39.6 ± 27.5 ng/ml at zero time and peaked at 4 hours ( 140.4 ± 76.4) ng/ml, after exogenous DHEA. The dehydroepiandrosterone sulfate (DHEAS) levels were 439.2±378.4 ng/ml at zero time, fluctuated with the lowest value at 8 hours (213.3 ±174.4) ng/ml, before and 1716.9 ± 1039.8 ng/ml at zero time and peaked at 8 hours (8762.8 ± 6361.0) ng/ml after exogenous DHEA. These data suggest that consumption of exogenous DHEA alters steroidal hormones composition in the body and that voluntary consumption of the substance could be predicted by determining T/epiT and DHEAS/DHEA glucuronate ratios in urine.
Key words:- A/Etio, 5α-diol/5β-diol, Dehydroepiandrosterone (DHEA), DHEAS/DHEA, GC/MSD, glucuronate, T/epiT.