DocumentsDate added
Case report:-Biochemistry
*Renu Nagar
*Department of Biochemistry, Dr. Rajendra Prasad Government Medical College, Tanda, Kangra, Himanchal Pradesh India.
Abstract:- A previously euthyroid, 55 years old malnourished woman admitted for elective surgery for multiple renal stones was found to have low T3 (60 ng/dl), low T4 (1.76 µg/dl), low TSH (0.144 mIU/ml) and moderately increased anti-TPO antibodies (179.0 IU/ml). Patient was clinically euthyroid, had no history of Thyroid illness, nor any symptoms or signs of Pituitary or Hypothalamic disorder. Thyroid biopsy showed degenerative changes. It was decided to defer her surgery till normalization of Thyroid profile. She was discharged from hospital with Thyroid hormone replacement. The patient’s T3 and T4 improved with Thyroxine, but TSH dropped further. Keywords:- Euthyroid sick syndrome; Non thyroidal illness; Renal stones, Pre operative; Stress; T3, T4,ESS, NIT, anti-TPO.
References:-
1.Kelly, NDG. Peripheral Metabolism of Thyroid Hormones: A Review . Altern Med Rev 2001; 5: 306-33.
2.Dayan CM. Interpretation of thyroid function tests . Lancet 2001; 357: 619–24.
3.Tandon N. Laboratory diagnosis of Thyroid disease: pitfalls. Capenews, 1997; 2.
4.Mastorakos G, Pavlatou M, Kandarakis ED, Chrousos GP. Exercise and the 5.Stress System, Hormones. 2005; 4: 73-89.
6.Gou DY, Su W, Shao YC, Lu YL. Euthyroid sick syndrome in trauma patients with severe inflammatory response syndrome. Clin J Traumatol 2006; 9: 115-7.
7.Reinhardt W, Mann K. Non-thyroid illness or changed thyroid hormone parameter syndrome with non-thyroid illnesses. Med Klin 1998; 93: 662-8.
8.Stathatos N, Wartofsky L. Perioperative management of patients with hypothyroidism. Endocrinol Metab Clin N Am 2003; 32: 503–18.
9.Girvent M, Maestro S, Hernández R, Carajol I, Monné J, Sancho JJ, Gubern JM, Sitges-Serra A. Euthyroid sick syndrome, associated endocrine abnormalities, and outcome in elderly patients undergoing emergency operation. Surgery 1998;123: 560-7.
10.Engler H, Riesen WF, Keller B. Anti-thyroid peroxidase (anti-TPO) antibodies in thyroid diseases, non-thyroidal illness and controls. Clinical validity of a new commercial method for detection of anti-TPO (thyroid microsomal) autoantibodies. Clin Chim Acta 1994; 225: 123-36.
11.McIver B, Gorman CA. Euthyroid sick syndrome: an overview. Thyroid. 1997; 7(1):125-32.
Copyright © 2013 Nagar Renu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article:- Neurosurgery
Lakshmi K1, Santhanam R2*,& Menezes GA1.
1Department of Microbiology. 2Department of Neurosurgery. Sree Balaji Medical College and Hospital, Chennai, India (Bharath University).
Abstract:- Schwannomas are slow-growing, benign tumors derived from schwann cells, the sheath cells that envelop myelinated nerve fibers. Intraosseous schwannomas have been observed, very rarely, in sacrum. We report an intraosseous sacral schwannoma and present the clinical, radiological, histological findings with surgical management and a follow up of 4 years. A 29 year old man presented with pain in the left gluteal region radiating to legs and deteriorating locomotor function. The neurological screening examination revealed no abnormality. The lumbosacral spine X-ray was normal. However, the lumbosacral spine Magnetic Resonance Imaging (MRI) showed a lesion at the S2 level extending from the left S1-S2 to the S3-S4 foramina with scalloping of the S1 and S2 components of the sacrum. Left S1-S3 hemilaminectomy and gross total excision of the tumor was achieved. Histology confirmed an intraosseous schwannoma and the patient’s clinical outcome was good after surgery. No recurrence observed in the 4 years of follow up. Hence diagnosis of such tumor in the earlier stage needs only minimal interventional procedure with better prognosis.
Keywords:- Intraosseous sacral schwannoma, Histology, X-ray, MRI.
References:-
1.Fawcett KJ, Dahlin DC. Neurilemmoma of bone. Am J Clin Pathol 1967; 47: 759-66.
2.Samter TG, Vellois F, Shafer G. Neurilemmoma of bone. Report of 3 cases and review of the literature. Radiology 1960; 75: 215-22.
3.Gordon EJ. Solitary intraosseous neurilemmoma of the tibia. Clin orthop 1976; 117: 271-82.
4.Chandhanarat Chandhanayingyong, Apichat Asavamongkolkul, Nittaya Lektrakul and Sorranart Muangsomboon. The Management of Sacral Schwannoma: Report of Four Cases and Review of Literature. Sarcoma 2008; sep 2: doi: 10.1155/2008/845132.
5.Dominguez J, Lobato RD, Ramos A, Rivas JJ, Gómez PA, and Castro S. Giant intrasacral schwannomas: report of six cases. Acta Neurochir (Wien) 1997; 139(10): 954–60. 6.Takeyama Masanobu, Koshino Tomihisa, Nakazawa, Akihiro, et al. Giant Intrasacral Cellular Schwannoma Treated With High Sacral Amputation. Spine 2001; 26(10): E216-9. 7.Guz BV, Wood DP Jr, Montie JE, Pontes JE. Retroperitoneal nerve sheath tumors: Cleveland clinic experience. J Urol 1989; 142: 1434-7.
8.Verstraete KL, Achten E, De Schepper A, Ramon F, Parizel P, Degryse H, et al. Nerve sheath tumors: evaluation with CT and MR imaging. J Belge Radiol 1992; 75: 311-20.
9.Miller PL, Tessler A, Alexander S. Pinck BD. Retroperitoneal Neurilemmoma. Urology 1978; 6: 619-23.
10.Abernathey CD, Onofrio BM, Scheithauer B, Pairolero PC, and Shives TC. Surgical management of giant sacral schwannomas. J Neurosurg 1986; 65(3): 286–95.
11.Pongsthorn C, Ozawa H, Aizawa T, Kusakabe T, Nakamura T and Itoi E. Giant sacral schwannoma: A report of six cases. Ups J Med Sci 2010; 115(2): 146-52.
12.Kotoura Y, Shikata J, Yamamuro T, Kasahara K, Iwasaki R, Nakashima Y, et al. Radiation therapy for giant intrasacral schwannoma. Spine 1991; 16(2): 239–42.
13.Feldenzer JA, McGauley JL, and McGillicuddy JE. Sacral and presacral tumors: poblems in diagnosis and management. Neurosurgery 1989; 25(6): 884–91.
14.Huvos AG and Woodard HQ. Postradiation sarcomas of bone. Health Physics 1988; 55(4): 631–6.
Original article:-
1*Swarnkar Madhusudan ,1Sheikh A.H., 3Singh Raghuveer, 1Mulla Shakila & 3Baig Vaseem N.
1M.D. Assistant Professor,2M.D. Professor and HOD, 3M.D. Associate Professor Dept. of PSM, Jhalawar Medical College, Jhalawar, Rajasthan, India.
Abstract: Background: Data related to acceptance of methods of family planning was present but not analyzed in a scientific method so this was an effort to analyze data of a tertiary care hospital of Rajasthan,India. Methodology: This was a hospital based retrospective study and monthly reports of family Planning acceptance from April 2010 March 2012 of Jhalawar Medical College and Hospital, Jhalawar, Rajasthan, India were analyzed. Results: Highest acceptance of sterilization was found in females (99%), of Hindu religion(78% to 83%) and of general caste(~66%), in the age group of 25-29 years(52%) and having parity two (40% to 54%) with low literacy (37% to 44%) during both years. Conclusions: Acceptance of permanent sterilization is completely by females only; only 1% males accepted this method of sterilization, parity 2 females compare to higher parity and illiterate females compared to literate ones accepted this method of sterilization more.
Key words:- Family Planning acceptance, Parity, Sterilization.
References:
1.J. kihore’s. National Health Programs of India, 9th edition, century publications New Delhi; P-121.
2.Gupta, U.; Kumar, P.; Bansal, A.; Sood, M.: Changing trends in the demographic profile and attitudes of female sterilization acceptors. The Journal of Family Welfare. Sept 1996; 42(3):27-31.
3.Govt. of India (1984), Year book Family Welfare Programe in India 1983-84, Ministry of Health, New Delhi.
4.K. Park. Text book of Preventive and Social Medicine, 21st edition, Banarsidas Bhanot Publishers, Jabalpur; p- 456-71,
5.Govt. of India (2010), Family Welfare Statistics in India 2009, Ministry of Health and Family Welfare, New Delhi. 6.Family Welfare statistics in India – 2011, Statistics Divisions, Ministry of Health and Family Welfare, Government of India. p - B-31- 40.
Conflict of interest: - Author have not declare any conflict of interest
Source of funding: - None
Copyright © 2013 Madhusudan Swarnkar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article:-Molecular and Cellular Engineering.
Amit Rastogi*& Poonam Singh. Department of Molecular and Cellular Engineering, Sam Higginbottom Institute of Agricultural, Technology and Sciences, Allahabad, U.P., 211007, India.
Abstract:- Present study was made to assess the heavy metal concentrations in the Carpet and Textile industries effluent collected from the different industries located in Bhadoi region. The effluent samples were analysed for metallic properties using Spectrophotometer Pharo 100 spectoquant (Merk, Millipore). For the characterization of heavy metals of various industrial effluents, some heavy metals like, Cadmium, Copper, Chromium, Iron, Nickel, Manganese, Lead, Zinc were analysed. In effluents samples, different metals were found in a concentration range Cadmium (0.014 – 0.018 mg/l), Copper (0.10 – 0.21 mg/l), Chromium (0.01 – 0.09 mg/l), Iron (0.54 – 2.2 mg/l), Nickel (0.78 – 1.55 mg/l), Manganese (0.04 – 0.13 mg/l), Lead (0.51 – 1.26 mg/l), Zinc (0.29 –1.24 mg/l). The result exhibited that the effluent samples from Mill 2, Mill 4, Mill 5 shown metal concentration under the limits as approved by FEMNEV and FEPA, 1991 standard limits where as effluent sample from mill 1 showed nickel, manganese and zinc concentration more than standard limit provided by FEMNEV and FEPA, 1991 where as effluent sample from mill 3 showed nickel concentration more than limit provided by FEPA, 1991.
Key words:- Textile industry; Heavy metals; Effluent; Spectrophotometer Pharo 100 Spectroquant; Bhadoi Region; Zinc; Lead; Cadmium.
Anatomical study:- Anatomy
Gopal Sharma1* & Tarun Vijayvergiya2
1Associate Professor, Department of Anatomy, Jhalawar Medical College, Jhalawar ,Rajasthan,India.
2Associate Professor, Department of Pharmacology, Jhalawar Medical College, Jhalawar, Rajasthan, India.
Abstract:- The left lung classically has one fissures, an oblique, dividing it into two lobes namely these are superior and inferior. The anomaly of the lobar pattern has been described by many research workers on CT scans and X- rays butthere are fewer studies on gross anatomical specimens. In the present case , which was incidentally detected, we report two fissures dividing the left lung into three lobes. Such abnormal fissures and lobes are clinically important for identifying broncho-pulmonary segments. Anatomical knowledge of anomalies of fissures and lobes of lungs may be important for surgeons performing lobectomies, radiologists interpreting X ray and CT scans and also academic interest to all medical personnel.
Key words:- Anomaly; Anatomical variation; Abnormal; Fissure; Lobe; Lung.
References:-
1.Ariyurek, O. M.: Gulsun, M. &Demirkazik, F. B. Accessory fissures of the lung: evaluation by high- resolution computed tomography. Eur. Radiol, 2001; 11:2449-53.
2.Dandy, W. E. Incomplete pulmonary interlobar fissure sign. Radiology, 1978; 128:21-5. 3.Godwin, J. D. & Tarver, R. D. Accessory Fissures of the Lung. A. J. 1984; 144:39-47. 4.Meenakshi, S.; Manjunath, K.Y. &Balasubramanyam, V. Morphological Variations of the Lung Fissures and lobes. The Indian J. of Chest Diseases & Allied Sciences.2004; 46: 179-82. 5.Standring S. Gray’s Anatomy. 39th ed. Churchill Livingstone, New York, 2005.pp. 947. 6.Walker, W. S. & Craig, S. R. A proposed anatomical classification of the pulmonary fissures. J. R. Coll. Surg. Edinburg., 1997; 42:233-4.