DocumentsDate added
Clinical study:-
Verma Madhurima1, Gupta Ritu 2, Porwal Sanjay K3*, Swarnkar Madhusudan 4 & Porwal Varsha5
1Assistant Professor,2Associate Professor, Department of Obstetrics and Gynaecology, 3Associate Professor, Department of General Surgery,4Assistant Professor, Department of community Medicine, 5Senior Demonstrator, Department of Anatomy, Jhalawar Hospital and Medical College Society, Jhalawar (Rajasthan)- India.
Abstract:- Background: Uterine leiomyoma is a common entity in premenopausal women. Only a subset of women is symptomatic and needs surgical treatment. Objective: To evaluate the clinical presentation, socio-demography, management outcome and its determinants in Rajasthan, India. Methods: This study was carried out at SMS Medical College Jaipur Rajasthan, a tertiary care hospital in Jaipur Rajasthan. Retrospective review of case records of all surgically managed cases of uterine leiomyoma over a period of 18 month done. Five hundred and eight women with uterine leiomyoma seen and managed surgically in Gynaecology Department. Results: Incidence of leiomyoma was 6.8% of gynaecological admission. The commonest presenting complaints were menstrual disorder (60.4%), abdominal pain (44.6%), abdominal lump (6.2%) and infertility (2.1%). The average uterine size at presentation was 6-8weeks (20.4%). The maximum number of cases 406(79.9%) were in age group of 31-50 years. Total abdominal hysterectomy done in (94.8%) cases. Conclusion: Uterine fibroid are commonly seen in premenopausal women and commonly present with menstrual disorders and may be associated with pelvic pain, infertility, pressure symptoms etc. The uterine size range from nonpalpable to 22 weeks pregnancy size. The treatment is abdominal hysterecetomy and myomectomy.
Keywords:- Uterine Leiomyomata, Menstrual disorder, Hysterectomy.
References:-
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Copyright © 2013 Porwal Sanjay K et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article:-
Baig Vaseem Naheed1*, Swarnkar Madhusudan2,Bhardwaj Ashok Kumar3, Singh Raghuveer4, Kewalramani Suresh5 & Soni Prashant6.
1Associate Professor,2Assistant Professor,3Professor,4Professor and Head, Department of P.S.M., Jhalawar Medical College, Jhalawar (Raj.), India.5Assistant Professor, Dept. of P.S.M., S. M. S. Medical College, Jaipur (Raj.),India. 6M.B.B.S., M.B.A., Maternal and Newborn health Manager, Save The Children, India.
Abstract: Background: HIV is the most prominent risk factor for progression of TB infection to disease causation and there is paucity of studies related to clinico-radiological profile of HIV-TB co-infection, this evoked us to do this study. Material and Methods: The present study is Hospital based cross sectional study done on two hundred HIV/AIDS patients (>15 year of age) attending ART Center of S.M.S. Medical College, Jaipur (Raj.). Results: Dual infection of HIV - TB was found in nearly one third (32.50%) of study individuals, co-infection was slightly more common in males (34.70%) than that of females (26.41%). Weakness was the almost universal (98.46%) symptom and muscle wasting was commonest (80.00%) sign, oral candidiasis was the most common (52.31%) complication. Of all the 65 HIV-TB co-infected patients, pulmonary TB was found in 18 patients (27.69%), extra-pulmonary TB in 27 (41.54%) patients, while 20 (30.76%) patients had both pulmonary & extra-pulmonary TB. upper zone infiltration & cavitatory lesion were seen in 47.37% while atypical features such as mid-lower zone infiltrate & exudative lesion were seen in 73.68% & 68.42%. Sputum smear positivity for AFB was found in 42.11% of pulmonary TB cases with HIV-TB co-infection. Most (90.77%) cases with HIV-TB co-infection had CD-4 count <200/ micro L.
Keywords: Extra-Pulmonary Tuberculosis, HIV-Tb co-infection, Pulmonary Tuberculosis.
References:-
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Copyright © 2013 Baig Vaseem N et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article:-Pharmacology
1Associate professor, Department of Pharmacology, 2Associate professor, Department of Anatomy, Jhalawar medical college, Jhalawar, Rajasthan, India.
Abstract:- Background:- There is great controversy about role of male sex hormone, testosterone, in Psychotic mental disorders like schizophrenia. This study assessed the effectiveness of testosterone in schizophrenic patients and probes how it modulates the action of standard anti-psychotic medication Chlorpromazine which is commonly used in Clinical Psychiatric practice. Methods, a. Design and Setting:- -Randomized, Double-blind, Controlled Clinical study performed in collaboration with Department of Clinical Psychiatry from Feb 2003 to March 2004 in M.Y.H Hospital (Teaching hospital) associated with M.G.M. Medical College, Indore. b. Subjects - twelve patients aged 20 to 60 years diagnosed Schizophrenics according to ICD-10 Criteria who visited in outpatient department of psychiatry during study period. c. Interventions - Patients was treated with Oral Chlorpromazine 200 mg BD, half of the 12 patients also received single dose of testosterone esters 100mg intramuscularly with above-mentioned treatment .d. Outcome Measure - how symptomology in schizophrenic patients affected is measured by applying various valid psychiatric rating scales like Brief psychiatric Rating Score (BPRS) , Scale for assessment of positive symptom(SAPS), and Scale for Assessment of Negative Symptoms (SANS) . Basal reading is followed by treatment intervention and then scales are used to measure the effect every week for 3 weeks. Paired‘t’ test is used for determining level of significance (p value) of intervention. Results: - Single dose of Testosterone 100 mg administered initially by I.M. route potentiated the reduction level in negative symptoms of schizophrenia by 115% in patients receiving chlorpromazine 200 mg. Conclusion:- In this study, Testosterone potentiated the effects of Chlorpromazine 200 mg, on general psychotic manifestations, positive symptoms and negative symptoms of schizophrenia, assessed on BPRS, SAPS and SANS scoring scales. The most significant is the effect on negative symptoms as measured by SANS.
Keywords:- Testosterone, Schizophrenia, Chlorpromazine.
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Copyright © 2013 Vijaywargia Tarun & Sharma Gopal. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Case report:-
T Mathew * *School Of Dentistry, International Medical University, Bukit Jalil, Kuala Lumpur , Malaysia, 57000.
Abstract:- Introduction: Functional appliance is an effective way of treating skeletal Class II malocclusion in children and adolescents. A 12-month mandibular advancement protocol with Twin Block appliance has been proved to enhance the condylar growth and to improve the mandibular retrognathism. Objective: The case report documented the treatment of a 12- year- old girl with skeletal class II malocclusion with over jet of 8mm, 100% Deep bite and Angle Class II molar, Class II canine and Class II incisor relationship. Method: The phase I Orthopedic stage treatment was done using Twin Block appliance for 12 months with mandibular advancement of 8mm including trimming of inter-occlusal bite plane of the Twin Block to facilitate the eruption of Mandibular molars. This was followed by a phase II Pre-adjusted Edgewise appliance therapy for finishing and detailing. Result: The treatment objective of normal overjet and overbite, skeletal class I by growth modification, class I molar relation, class I canine relation, class I incisor relation and lip competency were achieved. Conclusion: A stable harmonious occlusion was achieved after 20 months of treatment.
Key Words:- Functional appliances. Angle Class II malocclusion. Pre-adjusted Edgewise appliance.
References:-
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Copyright © 2013 Mathew T. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original research:-General Surgery
Yogesh Kumar1,Basavaraj G.Veerapur2,Sunil Kumar Math3 & YP Raghavendra Babu4* 1Professor, Department of General Surgery,2Assistant Professor, Department of General Surgery,3Postgraduate, Department of General Surgery,4Associate Professor, Department of Forensic Medicine and Toxicology, Kasturba Medical College (A Constituent College of Manipal University), Mangalore, India.
Abstract:- Background:Studies on the clinical outcome & biochemical alterations in the postoperative follow-up period in cases with Roux-en-Y jejunostomy compared with loop jejunostomy cases in upper GI surgeries are not many. Materials & Methods: In this observational study, a total of 28 cases undergoing upper GI Surgeries with eitherRoux-en-Y jejunostomy orloop jejunostomy method were included. Jejunal loop anastomosis or Roux en Y jejunal anastomosis was used as per the indications for case. During the follow up clinical evaluation, biochemical analysis, quality of life was obtained. Results: There was one mortality and four patients had significant morbidity. The average follow-up period was 16 months (range 3months – 16 months). Patients with Roux-en -Y anastomosis were significantly asymptomatic and had greater Visick I grading than patients with loop jejunal anastomosis. Clinical outcomes & quality of life was better in Roux-en-Y group. Biochemical analysis showed loop anastomosis group had significant post operative hypokalemia, hypoproteinemia with longer hospital stay. Conclusion: This pilot study showed that Roux-en-Y anastomosis is significantly better than jejunal loop anastomosis in upper GI surgeries with the subjective and biochemical analysis under evaluation. However further studies is required to confirm the findings.
Keywords:- Roux-en-Y; Jejunostomy; GI surgery; loop jejunostomy.
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Copyright © 2013 YP Raghavendra Babu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.