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Case report:- Anesthesia
Pravin Sonuji Sapkal1*, Sudhir Chavan2, V A Kurhekar3, Sampda Rajurkar4 & Prerna Nandedkar5.
1Assistant Professor, 2Head of Department, Dept of Anesthesia, 4Assistant Professor Department of PSM, 5Assistant Professor Department of Biochemistry, Government medical college Akola, Maharashtra, India. 3Associate Professor, Dept of Anesthesia, Government medical college, Miraj, Maharashtra, India.
Abstract:- To Study the effect of Hemoglobin Levels on the induction dose of thiopentone. Background: Thiopentone is the most commonly used induction agent. Its fate is intimately related linked to magnitude of its binding protein, which is deranged in anemia, hypoprotienaemia and A: G ratio. Aim: To evaluate the effect of hemoglobin level alone on the induction dose of thiopentone with normal level of protein, albumin and globulin. Setting and Design: Clinical trial to evaluate the possible interaction between hemoglobin levels and induction dose of thiopentone with the normal levels of proteins like albumin and globulin. Methods and Materials: It is the clinical trial conducted on patients of both sexes between the age of 15-50yrs of ASA grade I and II who follows the criteria during the period of Jan 2010 to Sept 2011. Total 80 subjects are selected in the study. Statistical Analysis used: Z test is used to find the significance. SPSS 17 is used for analysis. Result and conclusion: Dose of thiopentone (MID) in cases is less than that of control group. And it is statistically highly significant. MID of thiopentone is larger in higher hemoglobin concentration. Present study suggests that normal patients vary enormously in their response to thiobarbiturates. The dose of thiopentone sodium required for induction of anesthesia is less in patients with low hemoglobin levels. This may be due to anaemic hypoxia increasing the sensitivity of cerebral cell to drugs. Keywords:- Hemoglobin, induction dose, thiopentone.
References:-
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Copyright © 2013 Pravin S et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Clinical study:-
Verma Madhurima1, Gupta Ritu 2, Porwal Sanjay K3*, Swarnkar Madhusudan 4 & Porwal Varsha5
1Assistant Professor,2Associate Professor, Department of Obstetrics and Gynaecology, 3Associate Professor, Department of General Surgery,4Assistant Professor, Department of community Medicine, 5Senior Demonstrator, Department of Anatomy, Jhalawar Hospital and Medical College Society, Jhalawar (Rajasthan)- India.
Abstract:- Background: Uterine leiomyoma is a common entity in premenopausal women. Only a subset of women is symptomatic and needs surgical treatment. Objective: To evaluate the clinical presentation, socio-demography, management outcome and its determinants in Rajasthan, India. Methods: This study was carried out at SMS Medical College Jaipur Rajasthan, a tertiary care hospital in Jaipur Rajasthan. Retrospective review of case records of all surgically managed cases of uterine leiomyoma over a period of 18 month done. Five hundred and eight women with uterine leiomyoma seen and managed surgically in Gynaecology Department. Results: Incidence of leiomyoma was 6.8% of gynaecological admission. The commonest presenting complaints were menstrual disorder (60.4%), abdominal pain (44.6%), abdominal lump (6.2%) and infertility (2.1%). The average uterine size at presentation was 6-8weeks (20.4%). The maximum number of cases 406(79.9%) were in age group of 31-50 years. Total abdominal hysterectomy done in (94.8%) cases. Conclusion: Uterine fibroid are commonly seen in premenopausal women and commonly present with menstrual disorders and may be associated with pelvic pain, infertility, pressure symptoms etc. The uterine size range from nonpalpable to 22 weeks pregnancy size. The treatment is abdominal hysterecetomy and myomectomy.
Keywords:- Uterine Leiomyomata, Menstrual disorder, Hysterectomy.
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Copyright © 2013 Porwal Sanjay K et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.