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Research article:- Biochemistry and Molecular Biology
Bably Sabina Azhar1, Md. Monirujjaman2, Kazi Saiful Islam3, Md. Jahangir Alam2, Sadia Afrin2, Mohammad Abdullah-Al-Shoeb4, Md. Sabir Hossain3*.
1PhD, Associate Professor, Department of Applied Nutrition and Food Technology, Islamic University, Kustia, Bangladesh.
2MS, Research Officer, Department of Nutritional Biochemistry, icddr, b, Dhaka, Bangladesh. 3MS, Lecturer, Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka, Bangladesh.
2MS, Research Officer, Department of Nutritional Biochemistry, icddr, b, Dhaka, Bangladesh.
2MS, Research Officer, Department of Nutritional Biochemistry, icddr, b, Dhaka, Bangladesh.
4MS, Lecturer, Department of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, Bangladesh.
3PhD, Corresponding author, Associate Professor, Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka, Bangladesh.
Abstract:- Birth weight is a very important factor for the development of a newborn. In developing country like Bangladesh there is a large number of low birth weight (LBW) incidence. Parental socio-demographic and anthropometric factors are very important for baby’s growth. This study was carried out to observe the relationship between maternal socio-demographic factors and anthropometric characteristics with infant birth weight in a sample of mothers and infants from the South-west region of Bangladesh. A total of 343 pregnant women aged between 18-38 years, of who gave birth to live children, participated in our study. We found that age of mother to conceive and maternal education is related to infant birth weight. The percentage of adequate birth weight (3000 g) was found highest (37.9%) within the 26-30 year age group. Incidence of LBW was found highest (52.2%) among mothers who had never gone to school and lowest (0%) for the graduated mothers. Working at the pregnancy period is associated with birth weight of newborn and the incidence of LBW was lowest among the housewife mothers. LBW baby was greater for mothers residing in rural area than urban area. We also found that maternal Body Mass Index (BMI) is also an important factor for birth weight of the newborn and incidence of LBW among the newborn was 0% for the maternal BMI ≥25 before conception and ≥30 before delivery. In conclusion these findings demonstrated that maternal contributing factors towards body weight problems among the newborns. This information’s may be useful for the planning of health and nutrition programs as well as intervention strategies.
Keywords:- Low birth weight (LBW), Body mass index (BMI), Anthropometric.
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Copyright © 2013 Hossain Sabir et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article:- Orthopedics
Ajit Swamy1* & Amit Swamy2
1Professor, Department of Orthopedics, Pad Shri Dr DY Patil Medical College & Hospitals, Pimpri, Pune, Maharashtra, India.
2 Professor, Department of Orthopedics MIMER Medical College & Hospitals,Talegaon, Pune, Maharashtra, India.
Abstract:-
Background and Objectives: Intertrochantric fractures of femur constitute a vast majority of admissions in orthopedic wards. It is universally accepted that internal fixation with dynamic hip screw is the best method of treatment because it allows early stability and mobility. We performed a prospective review of intertrochantric fractures treated with dynamic hip screw in lateral position to ascertain whether fracture table is a must for surgery. Design and Setting: The surgeries were performed in Dr D Y Patil Medical College, pimpri,Pune, Maharashtra, India between feb2007 to mar 2008. Methods: Fifty patients (35 males & 15 females) admitted with intertrochantric fracture type 2,3 & 4 (Kyle classification) were treated with dynamic hip screw in LATERAL POSITION , SIMPLE TABLE and the results analyzed. Results: Average hospital stay was around 8 days, average time to union was 6 months.36% patients had excellent results, 46% good and 18 % had fair results according to Kyle’s criteria. Conclusions: Our results prove that dynamic hip screw can be fixed in lateral position on simple table and this obviates the need for a fracture table. However the surgical technique is demanding and requires practice and there is a learning curve.
Key Words:- Dynamic hip screw, intertrochantric fractures, lateral position.
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Copyright © 2013 Amit Swamy & Ajit Swamy. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article:-
T.A. Thaer * and P. Ellaiah College of Pharmaceutical Sciences, Andhra University, Visakhapatnam -530003 A.P., India.
* Present Address: Department of Medical Lab Sciences, Faculty of Allied Medical Sciences, Arab American University, P.O. Box 240, Jenin, Palestine.
Abstract:-
A Streptomycete sp (A2’) was selected as the best L-asparaginase producing strain among (53) isolates. The fermentations were conducted by shake flask. Among carbon sources used mannitol was found to be the best for L-asparaginase production, its optimum concentration being 0.1%. Casein and corn steep liquor were preferred nitrogen sources for L-asparaginase production, with optimum concentration of casein being 0.75 %. The optimum pH range for L-asparaginase production was 6.5 to 7.5, optimum being 7.0. The optimum incubation temperature was 28°C. The maximum production attained at 72 hours of incubation. A 10% level of inoculum was found to be optimal for L-asparaginase production. At ratio 1:10 v/v (Volume of medium per volume of flask), the activity of L-asparaginase was maximum. Agitation was shown to have influence on L-asparaginase production. L-asparagine substrate was found to be a good enzyme inducer. The culture conditions of the strain for L-asparaginase production were optimized. The maximum production rate of L-asparaginase was improved 3 folds under the optimal conditions.
Key Words:- Marine Actinomycetes, Streptomyces, L-asparaginase, production, optimization.
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Copyright © 2013 T.A. Thaer & P. Ellaiah. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article:-
Vijaywargia Tarun1*, Sharma Gopal2 & Madhusudan Swarnkar3
1Associate professor, Department of Pharmacology, 2Associate professor, Department of Anatomy, 3Assistant professor, Dept of PSM, Jhalawar medical college, Jhalawar, Rajasthan, India.
Abstract: Background– In the series of clinical studies conducted to evaluate effect of male sex hormone Testosterone in patient of schizophrenia(most common psychosis) and the way this hormone interact with anti-psychotic drugs , this was second study conducted by department of pharmacology in collaboration with department of Clinical Psychiatry. In this study the second generation anti-psychotic drug Risperidone is used. The aim of study focused to prove testosterone is useful adjuvant in schizophrenia and can be safely used with anti-psychotic drugs Risperidone. Methods – a. Design and Setting - Double-blind, RCT performed in Indian patients diagnosed of schizophrenia from Feb 2003 to March 2004 in teaching Hospital associated with M.G.M.M.C Indore. b. Subjects:-12 patients aged 20 to 60 years diagnosed schizophrenics according to ICD-10 Criteria, visited in outpatient department of Clinical psychiatry during study period. c. Pharmacological Interventions:- All patients were treated with oral Risperidone 2mg BD, in half of the 12 patient’s single dose of testosterone 100mg intramuscularly also administered. d. Measurement of patient outcomes:– validated psychiatric rating scales are used to evaluated the effect of pharmacological interventions on symptomology of schizophrenic patients .Scales used in clinical study are Brief psychiatric Rating Score (BPRS) , Scale for assessment of positive symptom(SAPS),and Scale for Assessment of Negative Symptoms (SANS). The data is recorded, reported and than analyzed with a help of statistician. Results: - Single dose of 100 mg I.M. initially testosterone potentiated the reduction level in negative symptoms of schizophrenia by 112% in Risperidone 2mg BD. Conclusion:- In this study, testosterone potentiated the effects of Risperidone 2mg BD on general psychotic manifestations, positive symptoms and negative symptoms of schizophrenia, as assessed on BPRS, SAPS and SANS scoring scales, specifically the major effect is on negative symptoms of schizophrenia. There is no increase in side effects as compared to control group.
Key words- Testosterone, Schizophrenia, Risperidone.
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Copyright © 2013 Vijaywargia Tarun et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article:-
G. Rajeswari, 1 M. Murugan2 & V.R.Mohan2*
1V. O.Chidambaram College of Education, Tuticorin, Tamil Nadu,India.
2Ethnopharmacology Unit, Research Department of Botany, V. O. Chidambaram College, Tuticorin, Tamil Nadu,India.
Abstract:-
Hugonia mystax L. belongs to the family Linaceae. It is commonly known as “Modirakanni”. The present investigation was carried out to determine the possible bioactive components of bark of Hugonia mystax L. using GC-MS analysis. Twenty compounds were identified. The prevailing compounds in ethanol extract were 2- Furan carboxaldehyde, 5– (hydroxyl methyl) – (27.64%), à-D-Glucopyranoside, methyl, (15.00%), n-Hexadecanoic acid (14.69%), 9,12-Octadecadienoic acid (Z,Z)- (7.24%), Oleic Acid (7.03%), Benzaldehyde, 2-hydroxy-6-methyl- [Synonyms: 2,6-Cresotaldehyde] (6.79%), Benzofuran, 2,3-dihydro- [Synonyms: Coumaran] (5.25%), Octadecanoic acid (2.24%), 1-Docosene (1.69%) and Stigmastan-6,22-dien, 3,5-dihydro- (1.49).
Key words:- Modirakanni, GC-MS, bioactive compounds, Phytol.
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Copyright © 2013 G.Rajeswari, M.Murugan & V.R.Mohan. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.