DocumentsDate added
Case report:-
Dhiraj B. Nikumbh1*, Nandkumar V. Dravid2, Priya S. Bagle3, Anjali M. Chitale4 & Chakor M. Rokade5
1Associate Professor,2Professor & Head,3Assistant Professor, 5Assistant Lecturer, Department of Pathology ,4 Professor, Department of Surgery, JMF’s ACPM medical college and hospital, Dhule, Maharashtra, India.
Abstract:-
Condyloma acuminata or genital wart is the anogenital expression of human papilloma virus (HPV) infection and is the most common viral sexually transmitted disease in the western world. Isolated condyloma acuminata of the thigh in absence of similar lesions on the genital areas are very uncommon. After extensive review of literature, only limited case reports were available of this rare entity. Herein, we present a case of condyloma acuminata of the left thigh in a 60 year old male in absence of any similar lesions on genital areas. The diagnosis was offered on cytology and histopathologically; as a result of curiosity due to its unusual appearance on gross features. We present this case due to its rarity and uncommon findings.
Keywords:- Condyloma acuminata, HPV, viral disease.
References:-
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Copyright © 2013 Nikumbh DB et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article:- Oral & Maxillofacial Surgery
Khaji. Shahanavaj. I*
Lecturer, Department of Oral & Maxillofacial Surgery, Tatyasaheb Kore Dental College & Research Centre, Mahatma gandhi hospital campus, New Pargaon- 416137. Kolhapur , Maharastra,India.
Abstract:- Background and objectives: In the last 15 years, the perception of transfusion of allogeneic blood in the surgical setting has moved from a benign intervention, sometimes life-saving, to an outcome to be avoided. The risks associated with allogenic blood transfusion are increasing recognized. Since then, an extensive literature has developed on the indications for, risks of, and alternatives to transfusion of allogeneic blood. The purpose of this study is to evaluate the effects & practical Limits of acute standardized normovolemic hemodilution in patients undergoing elective major maxillofacial surgery. Patients and methods: A total of 15 patients (7 Males, 8 Females, with age ranging from 17-30 years) undergoing elective major oral surgical procedures were randomly assigned for study evaluation. Following induction of general anesthesia, sequestration of 3-5mg/kg of fresh autologous blood was withdrawn anesthetist’s supervision. Blood was collected from peripheral venous lines into bags containing citrate-phosphate-dextrose-adenine-1 anticoagulant, labeled according to published guidelines and replaced simultaneously with a peripheral infusion of crystalloids at volume ratio. Transfusion requirements & post operative complications were recorded on the medical chart. Results & observations: In none of the patients (n=15) significant complications were evident except for in two patients (13%) who had low hemoglobin values post-operatively which were observed in 1st post-operative day. Two units of allogeneic blood were administered in two patients post-operatively. Retransfusion of ANH blood had no significant effect on clotting variables. Conclusion: In summary, the results of this study demonstrate that a standardized ANH harvesting a fixed volume of 350 – 500 ml of whole blood & not targeting a specific, low post ANH – hemoglobin can be considered as a safe, low time consuming & economic allogeneic blood conservation that could be offered to patients undergoing elective maxillofacial surgery, unless severe contra-indications are present. Meanwhile, further studies are necessary to define the efficacy & benefits of autologous transfusion after major elective surgical procedures. Meanwhile, further prospective clinical trials are needed to define the efficacy & benefits of autologous transfusion in major maxillofacial surgeries.
Keywords:- Acute normovolemic hemodilution (ANH); Isovolemic hemodilution; Autologous blood transfusion; Elective major maxillofacial surgeries.
References:-
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Copyright © 2013 Khaji Shahanavaj. I. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article:-
T.A. Thaer * and P. Ellaiah College of Pharmaceutical Sciences, Andhra University, Visakhapatnam -530003 A.P., India.
* Present Address: Department of Medical Lab Sciences, Faculty of Allied Medical Sciences, Arab American University, P.O. Box 240, Jenin, Palestine.
Abstract:-
A Streptomycete sp (A2’) was selected as the best L-asparaginase producing strain among (53) isolates. The fermentations were conducted by shake flask. Among carbon sources used mannitol was found to be the best for L-asparaginase production, its optimum concentration being 0.1%. Casein and corn steep liquor were preferred nitrogen sources for L-asparaginase production, with optimum concentration of casein being 0.75 %. The optimum pH range for L-asparaginase production was 6.5 to 7.5, optimum being 7.0. The optimum incubation temperature was 28°C. The maximum production attained at 72 hours of incubation. A 10% level of inoculum was found to be optimal for L-asparaginase production. At ratio 1:10 v/v (Volume of medium per volume of flask), the activity of L-asparaginase was maximum. Agitation was shown to have influence on L-asparaginase production. L-asparagine substrate was found to be a good enzyme inducer. The culture conditions of the strain for L-asparaginase production were optimized. The maximum production rate of L-asparaginase was improved 3 folds under the optimal conditions.
Key Words:- Marine Actinomycetes, Streptomyces, L-asparaginase, production, optimization.
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Copyright © 2013 T.A. Thaer & P. Ellaiah. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article:-
Jyoti Rana1*, Pushpa Thakur1 & M.S.Thakur2
1IIHS, Himachal Pradesh University Shimla, Himachal Pradesh -171005, India.
2Department of Biosciences, Himachal Pradesh University Shimla-171005, India.
Abstract:-
The present study was conducted to determine the effect of morphine sulfate on the developmental rate of Chrysomya megacephala (Fabricius, 1784). Investigation was carried out on four different weight pigs i.e. 2.5 kg, 2.5 kg, 2 kg and 2 kg. These were subjected to decomposition in two different toxic and nontoxic conditions. Insects play an important role in the decomposition process. Carrion may attract a wide range of necrophagous insect species with a variety of life history traits. Drug morphine sulfate was analyzed by screening tests, UV spectrophotometry and LC-MS analysis. Biological changes that occur in Chysomya megacephala (Fabricius) due to lethal dose of morphine sulfate was also reported and also give an important information on the necrophilous fauna for estimating postmortem interval in case of human death.
Keywords:- Chrysomya megacephala, Entomotoxicology, Opioid.
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Copyright © 2013 M S Thakur. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article:- Orthopedics
Ajit Swamy1* & Amit Swamy2
1Professor, Department of Orthopedics, Pad Shri Dr DY Patil Medical College & Hospitals, Pimpri, Pune, Maharashtra, India.
2 Professor, Department of Orthopedics MIMER Medical College & Hospitals,Talegaon, Pune, Maharashtra, India.
Abstract:-
Background and Objectives: Intertrochantric fractures of femur constitute a vast majority of admissions in orthopedic wards. It is universally accepted that internal fixation with dynamic hip screw is the best method of treatment because it allows early stability and mobility. We performed a prospective review of intertrochantric fractures treated with dynamic hip screw in lateral position to ascertain whether fracture table is a must for surgery. Design and Setting: The surgeries were performed in Dr D Y Patil Medical College, pimpri,Pune, Maharashtra, India between feb2007 to mar 2008. Methods: Fifty patients (35 males & 15 females) admitted with intertrochantric fracture type 2,3 & 4 (Kyle classification) were treated with dynamic hip screw in LATERAL POSITION , SIMPLE TABLE and the results analyzed. Results: Average hospital stay was around 8 days, average time to union was 6 months.36% patients had excellent results, 46% good and 18 % had fair results according to Kyle’s criteria. Conclusions: Our results prove that dynamic hip screw can be fixed in lateral position on simple table and this obviates the need for a fracture table. However the surgical technique is demanding and requires practice and there is a learning curve.
Key Words:- Dynamic hip screw, intertrochantric fractures, lateral position.
References:-
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