DocumentsDate added
Original article:-
VermaMadhurima1, Gupta Ritu2, Porwal K Sanjay3*, Gupta Sanjeev4 & SwarnkarMadhusudan5
Affiliation:-
1Assistant Professor, 2Associate Professor, Department of Gynecology & Obstetrics, 3Associate Professor, Department of Surgery, 4Senior Resident Department of Anaesthesia, 5Assistant Professor, Department of PSM, Jhalawar Medical College, Jhalawar, Rajasthan, India.
Abstract:
Objective: To evaluate the prevalence of pelvic pathology among patient with uterine fibroid.
Material & method: The study was carried out in indoor patient of Zanana Hospital Jaipur Rajasthan a tertiary center attached to SMS medical collage & Hospital Jaipur, Rajasthan,India.
The study was carried out over a period of 18 month.Included 7348 cases of gynaecological admission out of which 508 cases were of fibroid uterus. All cases of fibroid of uterus were studied & managed surgically & were confirmed by histopathological examination. During surgery a systematic inspection of the pelvis was carried out to know the prevalence of associated pelvic pathology other then fibroid.
Results: In present series associated pelvic pathology were present in 189 cases (37.2%).Incidence of fibroid uterus come out to be 6.8% of gynaecological admission. The most common associated pelvic pathology were PID seen in 123 (24.2%) cases, next common were adenomyosis seen with 32 cases (6.2%),simple serous cyst 25 cases (4.9%) endometrosis 6 cases (1.1%) papillary adenoma with 2 cases (0.39%) dermoidcyst associated with one case ( 0.19%) of fibroid uterus.
Key Words: Uterine leiomyoma; fibroid; adenomyosis.
References:
1. Briggs ND. Common gynaecologicaltumours. Tropical Journal of Obstetrics and Gynaecology.1995;12(12):62–71.Link
2. Evans P, Brunsell S. Uterine fibroid tumours: Diagnosis and treatment. American Family Physcian.2007;75:1503–1508.Pubmed
3. Lethaby A, Vollenhoven B. Fibroids (uterine myomatosis, leiomyomas) American Family Physcian.2005;71:1753–1756.Pubmed
Article citation:-
VermaMadhurima, Gupta Ritu, Porwal K Sanjay, Gupta Sanjeev & SwarnkarMadhusudan. To study the prevalence of pelvic pathology among patient with uterine myoma. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013, July; 32(32): 1279-1281. Available at http://www.jpbms.info.
Copyright © 2013 VermaMadhurima, Gupta Ritu, Porwal K Sanjay, Gupta Sanjeev & SwarnkarMadhusudan. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Clinical study
*1Dahiya Swati, 2Gupta Udayan,3Dodwad Vidya,4Kukreja Jha Bhavna & 5 Gupta Das Prafull.
Affiliation:
1Post graduate 3rd year, 2Professor, 3HOD & Professor, 4Senior Lecturer, Department of periodontics, I.T.S-CDSR, Murad Nagar , Ghaziabad, U.P, India.
5Senior Resident, Department of periodontics, KGMC, Lucknow, U.P, India.
Abstract:
Objective: To evaluate the effects of smoking on clinical parameters and enzyme activity of alkaline phosphatase in GCF in patients with chronic periodontitis before and after 30 days of scaling and root planing.
Method: A total of 20 patients (with a pocket depth ≥ 5 mm) were selected for the study. Patients were divided randomly into Test group (n=10) including current smokers and Control group (n=10) including non-smokers. The clinical parameters including plaque index (PI), gingival index (GI), pocket probing depth (PD), clinical attachment level (CAL) were recorded and GCF samples were collected for analysis of Alkaline phosphatase levels before and 30 days after scaling and root planing.
Results: In test group PI, GI (p<0.001) and ALP (p<0.002) levels were found to be statistically significant after scaling and root planing. No statistically significant results were found in relation to PD and CAL(p=0.268 and p=0.703 respectively).
Conclusion: The present study concluded that GI, PI, Pocket Probing Depth, CAL & ALP were reduced in smokers and non smokers after 30 days of initial periodontal therapy. Cigarette smoking has an effect on the levels of ALP in GCF in smokers.
Key Words: Alkailine phosphatase; Gingival crevicular fluid.
References:
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Article citation:
Dahiya Swati, Gupta Udayan, Dodwad Vidya, Kukreja Jha Bhavna & Gupta Das Prafull. The Enzyme activity of alkaline phosphatase in gingival crevicular fluid of smokers and non-smokers with chronic periodontitis before and after phase I therapy. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 July; 32(32): 1348-1353. Available at http://www.jpbms.info.
Copyright © 2013 Dahiya Swati,Gupta Udayan,Dodwad Vidya,Kukreja Jha Bhavna & Gupta Das Prafull. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
1Shweta Kumari Singh, MDS student, 2Sumit Malhotra, MDS, ITS Dental College, Department of Periodontology and Oral Implantology, ITS Dental College, Muradnagar, Ghaziabad, India.
Abstract:
Background: Over the past decade, it has become more apparent that stress can negatively influence the oral health status, which can lead to increased amounts of dental plaque, gingival inflammation and more severe periodontitis.
Materials & method: Twenty students who were in fourth year B.D.S were recruited for the study. Test group (n=10) subjects were selected from final year students who were appearing for their examination. Control group (n=10) subjects were selected from non- examination going fourth year students. A clinical examination included assessment of Turesky-Gilmore-Glickman modification of Quigley-Hein Plaque index, Gingival Index, bleeding on probing, PPD and clinical attachment levels. Saliva and GCF were collected for each subject for analysis of salivary cortisol and GCF alkaline phosphatase (ALP) levels. Students registered their perceived stress on a visual analogue scale (VAS).
Results: Exam going students had higher amounts of dental plaque (P < 0.001), gingival inflammation (P < 0.001) and clinical attachment level (p < 0.001) compared with after the exams. The amount of ALP levels in GCF were significantly increased during the time of examinations. The median levels of cortisol in saliva was also significantly raised in exam going students compared to non-exam going students. The results from the VAS registration revealed a significant difference (P < 0.001) between the two groups.
Conclusion: Academic stress appears to affect periodontal health, shown by more plaque accumulation, gingival inflammation and increased amounts of ALP in GCF and cortisol in saliva.
Key Words: Academic stress; cortisol; dental plaque; alkaline phosphatase; periodontal diseases.
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Article citation:-
Singh Shweta Kumari & Malhotra Sumit. The effect of academic stress on gingival inflammation. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013, July; 32(32): 1260-1264. Available at http://www.jpbms.info
Copyright © 2013 Singh Shweta Kumari & Malhotra Sumit. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
Original article:-
Garima Dhariwal1 and Sumit Malhotra2*
Affiliations:-
1Garima Dhariwal, MDS, student, 2Sumit Malhotra MDS, Professor, ITS Dental College, Department of Periodontology and Oral Implantology, ITS Dental College, Muradnagar, Ghaziabad, India.
Abstract:-
Background: The main objective of the present study was to evaluate the efficacy of tetracycline fibre used along with scaling and root planing for the treatment of chronic periodontitis and to compare the results with those treated with scaling and root planing alone.
Method: A total of 20 patients (having at least one site with a pocket depth ≥ 5 mm) were selected for the study. Patients were divided randomly into Test group and Control group. In the control group, periodontal pockets were treated with scaling and root planing alone. In the test group periodontal pocket were treated with scaling and root planing followed by placement of tetracycline fibres. Clinical parameters, Gingival Index, Plaque Index (Turesky, Gilmore and Glickman modification of Quigley-Hein Plaque Index) and aspartate transaminase levels in gingival crevicular fluid were recorded at baseline, 15days and 30 days. Sulcus bleeding index, pocket probing depth and clinical attachment level were recorded at baseline and 30 days.
Results: Both treatment modalities were affective in improving clinical parameters over one month observation period. The combined antimicrobial and mechanical debridement therapy has shown better results as compared with scaling and root planing alone.
Conclusion: Application of tetracycline in modified collagen matrix following scaling and root planing might be beneficial in treatment of chronic periodontitis and improving periodontal parameters.
Key Words: tetracycline HCl fibres; aspartate transaminase; GCF.
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Article citation:-
Dhariwal Garima and Malhotra Sumit. Tetracycline fibers plus scaling and root planing Versus Scaling and root planing alone in chronic periodontitis: effect on GCF aspartate transaminase level. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013, July; 32(32): 1265-1270. Available at http://www.jpbms.info.
Copyright © 2013 Dhariwal Garima and Malhotra Sumit. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article:-
*1G.Bhawani,2Ashutosh Kumar,3KSN Murthy & 4Neera Kumari
Affiliation:-
1Associate professor, Department of pharmacology, GSL Medical College & hospital, Rajahmundry, India
2Chief Interventional Cardiologist, GSL medical College & hospital, Rajahmundry, India.
3Head of the department, Department of pharmacology, GSL Medical College & hospital, Rajahmundry, India.
4Assistant professor, Department of Physiology,SRI Krishna medical college, Muzzafarpur, India.
Author’s contributions-All authors contributed equally to this paper.
Abstract:
Aim of study: The present study was designed with the aim of elucidating whether there exists any association between significant QTcd ( QT interval dispersion) and occurrence of complications in patients of acute myocardial infarction(AMI).
Methods & results: 60 patients with AMI admitted in intensive cardiac care unit during the period march 2012 to October 2012 were enrolled following inclusion/exclusion criteria’s. Variations in the QTcd were calculated for the patients from the time of admission till the day of discharge at a fixed time per day. Association between QTcd in (msec) and the eight complications taken as end point for the study was established. The mean time and age of the study population was 8±3.19 hours, 59 years respectively. A total of 48 patients developed complications. QTcd was significantly higher with complications of ventricular tachyarrythmias (7/60,83.6±24.6, CI 95%), left ventricular failure ( 7/60,76.5±14.1, CI 95%) . QTcd was very high in patients with pos tinfarct angina (3/60,108±36.030) and cardiogenic shock (6/60, 96±26.01). The most common complication observed was A-V block with significant QTCd in (15/60 , 63.16±32.2) Sudden death within 48 hours of thrombolysis having very high QTcd even at the time of Admission was observed in (5/60, 99.5 ± 13.79 to 110.62 ± 19.34 ).
Conclusion: QTcd was significantly higher in patients who developed complications except those with pericardial effusion and thromboembolism. There was no significant co-relation between the location of MI, QTc dispersion and development of complications. QTc dispersion was significantly very high in those patients with sudden death even at the time of admission.
Finally QT and QTc dispersion at admission and during stay in hospital may be used as an important non-invasive marker for prediction of various complications of AMI.
Key words: Acute myocardial infarction; QT interval; QTc dispersion; myocardial infarction complications.
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Article citation:-
Bhawani G.,Kumar Ashutosh ,Murthy KSN, Kumari Neera. Study of QT interval dispersion in acute myocardial infarction and its relationship with complications. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 July; 32(32): 1425-1431.Available at http://www.jpbms.info
Copyright © 2013 Bhawani G., Kumar Ashutosh, Murthy KSN, Kumari Neera K. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.