DocumentsDate added
Case study:-
*1Rohan Shanmuganathan & 2Indra Devi Subramaniam
Affiliation:-
1Klinik Kesihatan Serendah, Selangor, Malaysia.
2Multimedia University, Cyberjaya, Malaysia.
The name of the department(s) and institution(s) to which the work should be attributed:
Klinik Kesihatan Serendah, Hulu Selangor, Selangor, Malaysia.
Author’s contributions: - Both author contributed equally to this paper.
Abstract:
Background: The reemergence of Tuberculosis cases in Malaysia is a cause for concern. Several reasons have been attributed to this. Among these are the influxes of foreign workers, HIV and drug abuse.
Aim: To determine the socio-demographic characteristics of tuberculosis patients in Malaysia to test the veracity of the reasons attributed to the reemergence of TB cases in Malaysia. This study also examines the manifestation of the disease among Malaysians. Seven propositions were developed to be tested in this study based on literature review on the reemergence of TB cases worldwide.
Method: A total of 40 tuberculosis patients who had sought treatment at a Health Clinic during a one-year period were studied. Data was collected from their medical cards.
Results: Majority of the patients were Malaysians, males between the age of 21 to 50 years and unemployed. There did not seem to be an association between HIV positive cases and TB. Similarly there was no association between drug addiction and TB infection as majority of the patients were HIV negative and not drug users. Most of the cases were pulmonary TB. The most common symptoms were prolonged cough, weight loss and bloody sputum.
Conclusion: Propositions relating TB cases to economically productive age group, gender and poverty were supported by the findings of the study. The results did not support the propositions that reemergence of TB cases in Malaysia is due to influx of foreigners, increase in HIV positive cases, drug addiction and drug related HIV positive cases.
Key Words: Tuberculosis; HIV; drug abuse; socio-demography; Malaysia.
References:
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Article citation:-
Rohan Shanmuganathan & Indra Devi Subramaniam. Socio-demography of tuberculosis patients in Malaysia: Case study of Klinik Kesihatan Serendah. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 July; 32(32): 1353-1361. Available at http://www.jpbms.info.
Copyright © 2013 Rohan Shanmuganathan & Indra Devi Subramaniam. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article:-
Ebert R. Cumpa, M.D. 1, 2 & Oscar G.Pamo, M.D., F.A.C.P. 1,2
Affiliation:-
1 Internist, Department of Medicine, National Hospital ArzobispoLoayza, Lima.
2Faculty of Medicine Alberto Hurtado, Peruvian University Cayetano Heredia, Lima.
Abstract:
Objective: To know the sensitivity of the Candida spp. to the most common antimycotic antibiotics in cultured samples from patients without a previous antifungal treatment.
Material and Methods: A prospective, cross-sectional and descriptive study was carried out with the isolated positive cultures for Candida spp. in the Microbiology Laboratory of the National Hospital ArzobispoLoayza, Lima. The used culture was Sabouraud´s agar and the sensitivity was evaluated with Fungitest®. Eighty six positive cultures for Candida spp. were studied.
Results: The isolated species were: C. albicans 51 (59,3 %), C. tropicalis 22 (25,6%), C. parapsilosis 8 (9,3 %), C. famata 4 (4,7 %) and C. rugosa1 (1,1 %). The general sensitivity for Candida spp. was: 5-fluorocitosine 92%, anfotericin B 90%, miconazole 49%, ketoconazole 84%, itraconazole 37% and fluconazol 85%.
Conclusion: Candida spp. had a very good sensitivity for 5-fluorocitosine, anfotericin B and fluconazole.
Key words: Candida spp., sensitivity, resistance, antifungal antibiotic, 5-fluorocitosine, anfotericin B, fluconazole.
References
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14. Clinical and Laboratory StandardsInstitute.Method for antifungal disk diffusionsusceptibility testing of yeasts. Approved Guidelines-Second Edition. CLSI document M44-A2.Vol 29 N 17. 2009.
15. Pfaller MA, Bale M, Buschelman B, Lancaster M, Espinel-Ingroff A, Rex JH et al. Quality control guidelines for National Committee for Clinical Laboratory Standards -recommended broth macrodilution testing of amphotericin B, fluconazole and flucytosine. J ClinMicrobiol 1995; 33:1104-7.
16. Horn DL, Neofytos D, Anaissie EJ, Fishman JA, Steinbach WJ, Olyaei AJ et al. Epidemiology and outcomes of candidemia in 2019 patients: data from the prospective antifungal therapy alliance registry. Clin Infect Dis 2009; 48:1695-703.
17. Pfaller M, Diekema D, Gibbs D, Newell V, Meis J, Gould I et al. Results from the ARTEMIS DISK Global Antifungal Surveillance Study, 1997 to 2005: an 8.5- year analysis of susceptibilities of Candida species and other yeast species to fluconazole and voriconazole determined by CLSI standardized disk diffusion testing. J ClinMicrobiol 2007; 45: 1735-45.
18. Rivas J, Cortés J, Cuervo S, Vanegas E, Bermúdez D. Resistencia al fluconazol en aislamientos clínicos de Candida en un centro de referencia de pacientes con cáncer. Libro de Resúmenes V Congreso Panamericano de Control de Infecciones y Epidemiología Hospitalaria y I Congreso Peruano de Control de Infecciones Hospitalarias. Rev Peruana EnfInfecTrop 2004. 7-10 oct. Lima-Perú.
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20. Pfaller, MA, Boyken, L, Hollis, RJ, et al. In vitro susceptibilities of clinical isolates of Candida species, Cryptococcus neoformans, and Aspergillus species to itraconazole: global survey of 9359 isolates tested by Clinical and Laboratory Standards Institute broth microdilution methods. J ClinMicrobiol 2005; 43: 3807. 21. Pfaller MA, Messer SA, Boyken L, Tendolkar S, Hollis RJ and Diekema DJ. Selection of a surrogate agent (fluconazole or voriconazole) for initial susceptibility testing of posaconazole against Candida spp.: results from a global antifungal surveillance program. J ClinMicrobiol 2008; 46:551-9.
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Article citation:-
Ebert R. Cumpa & Oscar G.Pamo. Sensitivity of isolated Candida species in untreated patients. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 July; 32(33): 1287-1292.
Copyright © 2013 Ebert R. Cumpa & Oscar G.Pamo. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article:-
*1Sanjay Wagh, 1Mohan Raut, 1Sampada Rajurkar, 2Santoshi S Wagh & 3Diwakar Sharam
Affiliation:-
1Assistant Professor, Department of, Community Medicine Government Medical College Akola, Maharashtra, India.
2(L.M.O) Municipal Corporation Hospital, Badnera Amravati, Maharashtra, India.
3Assistant Professor (Stat), GMERS Medical College Dharpur. Patan, Gujarat, India.
Abstract:
Rabies is a fatal disease for which there is no cure and is seen worldwide. Rabies continues to be a serious public health problem in India and other developing countries. In India the data on animal bite in country is scanty, unreliable and controversial due to poor surveillance / reporting system. Cases of animal bite contribute to a problem of considerable magnitude in terms of days lost from work in search of appropriate treatment and financial loss. There are many myth and false beliefs associated with wound management. This includes application of oil herb, and red chilly, on wound inflicted by rabid animal.
Objective: To study epidemiological characteristic of dog bite injury and to study pre treatment practices among the study population.
Material & Method:
A cross sectional study of 636 animal bite victim reported at ARV clinic of Government Medical College and tertiary care hospital, Akola for medical advice and post exposure immunization against rabies during past three months has been done. Statistical analysis was done by EPI info software.
Result: Out of 636 most common animal bite was dog as 92.45% gives the history of dog bite. Majority i,e (72.48%) of the cases were Male. Maximum no (25.47%) of cases belongs to 21 to 30 years of age group. Lower limb was the most common (70.29%) biting site and majority (88.66%) had Category III bites. Maximum number (39.15%) of cases wash the biting site with plain water fallowed by soap and water other local remedies like lime and turmeric powder were used as pre treatment management of wound.
Conclusion: There is need to create the awareness in community about proper management of wound
Key Words: Animal bite, site of bite, pretreatment practice.
References:
1.Vyas Sheetal, Gupta Kinnari, Bhatt Gneyaa, Tiwari Hemant. Animal Bite Management Practices. A Study At Three Municipal Corporation Hospital Ahamadabad: National Journal of Community Medicine 2010; 1(2): 75-8.
2.Nitheshkumar, B.Kiranmai. A Study of Awareness and practices on Dog bites among rural women,Hyderabad, India. J Pharm Biomed Sci. 2012 Novemeber; 24 (24); 121-4.
3.Praveen Kulkarni, Renuka M, Sunil Kumar D, Hugara Siddalingappa, Ashok NC, Rama VH. Internation Journal of Health and Sciences. 2013; 3(4):11-6.
4.Mohd Junaid, Tabrez Ahmad, Gumashta R,Deoke A R. Epidemiological Study Of Dog Bite Victims In Anti Rabies Clinic Of A Tertiary Care Hospital. International Journal of Biological and Health Sciences. 2012; 1(1):12-6.
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6.Abhshek Singh, Anu Bhardwaj, Prassana Mihitra, Adiba Siddiqui, Surendar K Ahuwali. Across sectional Study of Knowledge Attitude and Practices of General practitioner regarding Dog bite Management in northern India. Medical Journal of D.Y Patil University.2013;6(2):142-5.
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8.Anita Khokhar, G.S. Meena, Malti Mehra. Profile of dog bite cases attending m.c.d. dispensary at Alipur, Delhi 2003. Indian Journal of Community Medicine Vol. XXVIII, No.4: 157-60.
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10.Dr. (Mrs.) Renu Bedi, Dr. D.K. Bedi, Dr. Anoop Tankha, Dr. Vinod Choudhary, Dr. R.S. Matoria Profile of Animal Bite Cases Attending Anti Rabies Clinic of J.L.N. Medical College & Hospital, Ajmer. APCRI:8(1).
11.M.K Sudarshan, B.J Mahandra, S.N Madhusudana, DH Aswath Narayana Abdul Rahaman, et al. An Epidemological Study of Animal Bite in India Result of a WHO Sponsored National Muticentric Rabies Survey.J Commun.Dis. 2006;38(1): 32-9 .
12.Bajwa MA, Manzoor S, Anjum A. Dog bites; assessment of burden, determinants and public services available for their victims in District Lahore. Professional Med J Sep-Oct 2012;19(5): 700-9.
13. Ichhpujani RL et al. Epidemiology of Animal Bites and Rabies cases in India. A Multicentric study. J Commun.Dis. 40 (1) 2008: 27-36
14.TR Behera, D M Satapathy, RM Tripathy, A Sahu.Profile of animal bite cases attending the ARC of M.K.C.G. Medical College, Berhampur (Orissa).APCRIjournal. 2008; 9(2).
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17.Agrwal N, Reddaih VP. Knowledge, Attitude and Practice Following Dogs Bite: A Community Based Epidemiological Study. Health and Population Perspective issue 2003;26(4):154-61.
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19.Jagvir Singh, D.C. Jain, Rajesh Bhatia, R.L. Ichhpujani, A.K. Harit, *R.C. Panda et al.,
Epidemological Charecterstic of Rabies in Delhi Surronding Area.Indian Peditrics 2001;38: 1354-60.
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Article citation:-
Sanjay Wagh et al. Profile of animal bite in Vidarbha region of Maharashtra, India. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 July; 32(33): 1381-1385.
Copyright © 2013 Sanjay Wagh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Case report:-
Dhiraj B.Nikumbh1, Priya S.Bagle2,Chakor M.Rokade3, Sashikant Nikam4, Yogesh R.Tayade3
Affiliation:-
1* MD, Associate Professor, 2MD, Assistant Professor, 3MBBS, Assistant Lecturer, Dept Of Pathology, JMF’s ACPM medical college, Dhule, Maharashtra, India.
4 MS, Consultant Surgeon, Private Hospital. Maharashtra, India.
Author’s contribution: - All authors contributed equally to this paper.
Abstract:
Primary adenoid cystic carcinoma (ACC) of the breast is an uncommon histological form of breast cancer accounting for 0.1% of all mammary neoplasm. ACC of the breast has favorable prognosis, contrasting to the aggressive nature of the ACC at other sites like head and face especially salivary gland. It has a biological cancer of slow progression and near absence of lymph nodes metastasis. To date about 150 cases of ACC are reported in literature so far.
We are presenting a case of adenoid cystic carcinoma in a 38 year old female presented with painless mass in right breast. ACC may mimic the most common form that is intraductal carcinoma on clinical, mammography and sonography. Accurate histopathological diagnosis is always warranted, in view of its rare nature but with favorable prognosis. We report this case due to its rarity with good prognostic value if proper and early diagnosed on histopathology.
Key Words: Adenoid cystic carcinoma; breast; mammary neoplasm.
References:
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2.Law Ym, Quck ST, Tan PH, Wang SLJ. Adenoid cystic carcinoma of the breast. Singapore Med J. 2009;50;e8-e11.
3.Peter GN, Wolff M. Adenoid cystic Carcinoma of the breast. Report of 11 new cases: Review of the literature and discussion of biological behaviour. Cancer. 1983;52:680-6.
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13.Muslimani AA, Ahluwalia MS , Clark CT, Daw HA. Primary Adenoid cystic carcinoma of the breast: Case report and review of the literature. International Seminars in Surgical Oncology. 2006; 3(17):1-4.
Article citation:
Nikumbh DB et al. Primary adenoid cystic carcinoma of the breast. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 June; 31(31): 1378-1380. Available at http://www.jpbms.info.
Copyright © 2013 Nikumbh DB et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original research article:-
*1Agarwal Kishor Kumar, 2Vidya P, 3Dutt Hemant Kumar,4Saxena Alok, 5Mittal Amit & 6 Mukherjee Sukhes
Affiliation:-
1Associate Professor, Anatomy, 2Senior Resident, Anatomy, 3Assistant Professor, Pharmacology, 4Senior Resident, Anatomy, 5Statistician, Community Medicine, 6Assistant Professor, Bio Chemistry, Veer Chandra Singh Garhwali Govt. Medical Sciences and Research Institute, Srinagar (Garhwal), Uttarakhand, India.
Author contributions: - All authors contributed equally to this paper.
Abstract:
Finger print identification is an important tool for medico legal cases. They are assessed on the basis of their different patterns. They are developed during fourth month of intrauterine life and remain unchanged throughout the life. They are hereditary and show the personality of a person as well as his/ her psychological behavior. Study of frequency of finger print pattern and their repetition on all fingers of normal population & prisoners was carried out.
Aims and objectives: To detect the frequency of finger print patterns on each digit and their comparison in two different groups comprising normal hilly population and prisoners.
To access the repetition of specific pattern on individual digit of both hands.
Methods: Fifteen hundred finger prints were collected using ink technique from both groups and carefully observed.
Statistical analysis:- The difference in proportions test is used to determine significant relationship of variables. p value was marked at 95 % confidence level (p < 0.05).
Results: Whorls were most frequent on ring finger where as loops were more on little finger. Highest frequency of arches was observed on index finger and composites were unevenly distributed.
Conclusion: This study correlates the personality of an individual with different finger print pattern as well as the prevalence of most frequent pattern on a specific digit. This study may be a favorable finding to predict the finger print pattern in case of missing phalanges for medico legal investigations.
Key Words: Arch; Composite; Finger print pattern; Friction ridges; Loop, Whorl.
References
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2.Barnes JG. "Chapter 1: History", in The Fingerprint Sourcebook, International Association for Identification, Ed. Washington DC: National Institute of Justice. 2009.
3.Cummins H, Midlo C. Palmar and plantar epidermal ridge configurations in European Americans. Am J Phys Anthrop 1926; 9: 471-502.
4.Henry Edward R. "Classification and Uses of Finger Prints". George Rutledge an Sons Ltd. London.1900.
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6.Hutchinson BB. Your Life in Your Hands. Neville Spearman Ltd, London.1967, pp 92-107.
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8.Cummins H, Midlo C. Finger Prints, Palms and Soles: An Introduction to Dermatoglyphics. The Blakiston Company, Philadelphia. 1943;p 9.
Article citation:-
Agarwal Kishor Kumar et al. Prevalence of digital dermatoglyphic patterns: Medico legal significance. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013, July; 32(32): 1338-1342. Available at http://www.jpbms.info.
Copyright © 2013 Agarwal Kishor Kumar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.