DocumentsDate added
Case study:-
*1El hag, Wafa, I, PhD. & 2Mahmoud ,Mohaned ,I H.
Affiliation:-
1Assistant professor – microbiology department, faculty of Medical Laboratory Sciences, Al-Neelain University, Khartoum, Sudan
2MSc. Student, faculty of Medical Laboratory Sciences- Sudan University of Science and Technology, Sudan.
Authors’ contributions
Both author contributed equally to this paper.
Abstract:
Objectives: this study aimed to determine the frequency of human immunodeficiency virus (HIV) antibodies (IgG, IgM) among blood donors attending National Blood Transfusion Center- in Khartoum during period April 2012.
Materials & Methods: One hundred and eighty blood donors were enrolled in this study. Blood specimens collected and examined by ELISA technique (fourth generation).
Results: The anti HIV antibodies were detected among 2 (1.1%). Most of the donors examined were male176 (96.5%), young adult (21-30), and most of them were single 72 (42.5%).The study showed that there is no significant relationship between the positive results and the history of previous surgical operation, or blood transfusion because no one from the studied population had a history of blood transfusion.
Conclusion: The frequency of anti HIV antibodies among the studied population is not high, but, people working in blood transfusion center must take good care when they handle blood bags and specimens, and destroy any positive results.
Key Words: HIV, antibodies (IgG, IgM) , blood donors, ELISA technique.
References:
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9.Elfaki , A. H., Eldour, A. A., Elsheikh, N. M. Sero-prevalence of immunodeficiency virus, hepatitis B and C and syphilis among blood donors at ElObeid Teaching Hospital, West Sudan Journal of Medical Science 2008;3 (4):333-8.
10.Taha, M.A. “Seroprevelance of HIV among Blood Donors” Sudan medical.J 2011:33.
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Article citation:-
El hag, Wafa I. & Mahmoud, Mohaned I H. Frequency of HIV among blood donors attending national blood transfusion center-Khartoum,Sudan. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 July; 32(32): 1362-1366. Available at http://www.jpbms.info.
Copyright © 2013 El hag, Wafa I. & Mahmoud, Mohaned I H. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Case study:-
*1Rohan Shanmuganathan & 2Indra Devi Subramaniam
Affiliation:-
1Klinik Kesihatan Serendah, Selangor, Malaysia.
2Multimedia University, Cyberjaya, Malaysia.
The name of the department(s) and institution(s) to which the work should be attributed:
Klinik Kesihatan Serendah, Hulu Selangor, Selangor, Malaysia.
Author’s contributions: - Both author contributed equally to this paper.
Abstract:
Background: The reemergence of Tuberculosis cases in Malaysia is a cause for concern. Several reasons have been attributed to this. Among these are the influxes of foreign workers, HIV and drug abuse.
Aim: To determine the socio-demographic characteristics of tuberculosis patients in Malaysia to test the veracity of the reasons attributed to the reemergence of TB cases in Malaysia. This study also examines the manifestation of the disease among Malaysians. Seven propositions were developed to be tested in this study based on literature review on the reemergence of TB cases worldwide.
Method: A total of 40 tuberculosis patients who had sought treatment at a Health Clinic during a one-year period were studied. Data was collected from their medical cards.
Results: Majority of the patients were Malaysians, males between the age of 21 to 50 years and unemployed. There did not seem to be an association between HIV positive cases and TB. Similarly there was no association between drug addiction and TB infection as majority of the patients were HIV negative and not drug users. Most of the cases were pulmonary TB. The most common symptoms were prolonged cough, weight loss and bloody sputum.
Conclusion: Propositions relating TB cases to economically productive age group, gender and poverty were supported by the findings of the study. The results did not support the propositions that reemergence of TB cases in Malaysia is due to influx of foreigners, increase in HIV positive cases, drug addiction and drug related HIV positive cases.
Key Words: Tuberculosis; HIV; drug abuse; socio-demography; Malaysia.
References:
1.World Health Organisation. WHO Global Tuberculosis Control Report, 2012.
2.World Health Organisation.WHO Global Tuberculosis Control Report 2010.
3.Ministry of Health Malaysia. National Tuberculosis Control Programme, Disease Control Division: 2008
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5.Tan CC. Return of an Old Scourge. NST 1998; July 1, 2007.
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8.Doctors Without Borders. Tuberculosis: New Faces of an old disease. Special Report, 2009.
Available from: http://www.doctorswithoutborders.org/publications/article. cfm?id=3507. 2009.
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10. Frieden TR, Sterling TR, Munsiff SS, Watt CJ, Dye C. Tuberculosis. Lancet 2003; 362(9387):887-899.
11.Somma D, Thomas BE, Karim F, Kemp J, Arias N, Auer C, Gosoniu GD, Abouihia A, Weiss MG. Gender and socio-cultural determinants of TB-related stigma in Bangladesh, India, Malawi and Colombia, 2008; 2(7):856-66.
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Article citation:-
Rohan Shanmuganathan & Indra Devi Subramaniam. Socio-demography of tuberculosis patients in Malaysia: Case study of Klinik Kesihatan Serendah. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 July; 32(32): 1353-1361. Available at http://www.jpbms.info.
Copyright © 2013 Rohan Shanmuganathan & Indra Devi Subramaniam. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article:-
*1Nandedkar Prerna D.,2Sonune Sanjay.,3Chitta Shrinivas S.,4Rajurkar Sampada R
Affiliation:-
1Assistant professor, 2Professor Department of biochemistry,3Junior resident, Department of physiology,4Assistant professor, Department of PSM Government medical college, Akola (M.S), India.
Abstract:
An epidural catheter even after safe insertion & Incidence of chronic kidney disease (CKD) is increasing worldwide and show poor outcome. The correct mechanism responsible for hyperlipidemia in the patients of CKD with NS is not understood. There are very few evidences showing hyperlipidemia in patients of CKD without NS. Therefore present study is undertaken to study lipid profile pattern in CKD and compare lipid profile in CKD with NS and CKD without nephrotic syndrome.
Aims: To estimate and compare lipid profile pattern in patients of CKD with NS and CKD without NS
Settings and designs: This cross sectional study was undertaken in the Department of Biochemistry of Government Medical College Nagpur, Maharashtra.
Material and method and statistical analysis: lipid profile was analyzed and compared between 50 age & sex matched CKD withNS cases (group I) and CKD without NS cases (group II) and normal healthy subjects control of age group 20-60 years using unpaired two‐tailed Student‘t’ test.
Results: Values of total cholesterol (p<0.001), triglyceride (p<0.001), LDL-C (p<0.001) and were significantly higher in CKD with NS (group I) and CKD without NS (group II) as compare to controls but values of HDL-C (p<0.001) were significantly lower compared to controls. Also, Values of total cholesterol (p<0.001), triglyceride (p<0.001), LDL-C (p<0.001) and were significantly higher in (group I) as compared to (group II) but values of HDL-C (p>0.05) were insignificant in (group I) as compared to (group II)
Conclusion: hyperlipidemia causes high cardiovascular risk and futher renal impairement in patients of CKD with NS as compared to CKD without NS.
Key words: (CKD) Chronic kidney disease; Hyperlidemia; (NS) nephrotic syndrome.
References:
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Article citation:-
Nandedkar Prerna D.,Sonune Sanjay., Chitta Shrinivas S., Rajurkar Sampada R. Comparative study of hyperlipidemia in patients of CKD with nephrotic syndrome and CKD without nephrotic syndrome. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 July; 32(32): 1396-1399.Available at http://www.jpbms.info.
Copyright © 2013 Nandedkar Prerna D.,Sonune Sanjay.,Chitta Shrinivas S.,Rajurkar Sampada R.. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Case report:-
Dhiraj B.Nikumbh1, Priya S.Bagle2,Chakor M.Rokade3, Sashikant Nikam4, Yogesh R.Tayade3
Affiliation:-
1* MD, Associate Professor, 2MD, Assistant Professor, 3MBBS, Assistant Lecturer, Dept Of Pathology, JMF’s ACPM medical college, Dhule, Maharashtra, India.
4 MS, Consultant Surgeon, Private Hospital. Maharashtra, India.
Author’s contribution: - All authors contributed equally to this paper.
Abstract:
Primary adenoid cystic carcinoma (ACC) of the breast is an uncommon histological form of breast cancer accounting for 0.1% of all mammary neoplasm. ACC of the breast has favorable prognosis, contrasting to the aggressive nature of the ACC at other sites like head and face especially salivary gland. It has a biological cancer of slow progression and near absence of lymph nodes metastasis. To date about 150 cases of ACC are reported in literature so far.
We are presenting a case of adenoid cystic carcinoma in a 38 year old female presented with painless mass in right breast. ACC may mimic the most common form that is intraductal carcinoma on clinical, mammography and sonography. Accurate histopathological diagnosis is always warranted, in view of its rare nature but with favorable prognosis. We report this case due to its rarity with good prognostic value if proper and early diagnosed on histopathology.
Key Words: Adenoid cystic carcinoma; breast; mammary neoplasm.
References:
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Article citation:
Nikumbh DB et al. Primary adenoid cystic carcinoma of the breast. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 June; 31(31): 1378-1380. Available at http://www.jpbms.info.
Copyright © 2013 Nikumbh DB et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Clinical study
*1Dahiya Swati, 2Gupta Udayan,3Dodwad Vidya,4Kukreja Jha Bhavna & 5 Gupta Das Prafull.
Affiliation:
1Post graduate 3rd year, 2Professor, 3HOD & Professor, 4Senior Lecturer, Department of periodontics, I.T.S-CDSR, Murad Nagar , Ghaziabad, U.P, India.
5Senior Resident, Department of periodontics, KGMC, Lucknow, U.P, India.
Abstract:
Objective: To evaluate the effects of smoking on clinical parameters and enzyme activity of alkaline phosphatase in GCF in patients with chronic periodontitis before and after 30 days of scaling and root planing.
Method: A total of 20 patients (with a pocket depth ≥ 5 mm) were selected for the study. Patients were divided randomly into Test group (n=10) including current smokers and Control group (n=10) including non-smokers. The clinical parameters including plaque index (PI), gingival index (GI), pocket probing depth (PD), clinical attachment level (CAL) were recorded and GCF samples were collected for analysis of Alkaline phosphatase levels before and 30 days after scaling and root planing.
Results: In test group PI, GI (p<0.001) and ALP (p<0.002) levels were found to be statistically significant after scaling and root planing. No statistically significant results were found in relation to PD and CAL(p=0.268 and p=0.703 respectively).
Conclusion: The present study concluded that GI, PI, Pocket Probing Depth, CAL & ALP were reduced in smokers and non smokers after 30 days of initial periodontal therapy. Cigarette smoking has an effect on the levels of ALP in GCF in smokers.
Key Words: Alkailine phosphatase; Gingival crevicular fluid.
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Article citation:
Dahiya Swati, Gupta Udayan, Dodwad Vidya, Kukreja Jha Bhavna & Gupta Das Prafull. The Enzyme activity of alkaline phosphatase in gingival crevicular fluid of smokers and non-smokers with chronic periodontitis before and after phase I therapy. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 July; 32(32): 1348-1353. Available at http://www.jpbms.info.
Copyright © 2013 Dahiya Swati,Gupta Udayan,Dodwad Vidya,Kukreja Jha Bhavna & Gupta Das Prafull. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.