DocumentsDate added
Case report
Sridhar. C1,Krithika. C2,Uma Maheswari. S3,Ponni. V4,Praveena. NM4,PriyaRamani2.
Affiliation:-
1Associate Professor of Medicine, Department of Internal Medicine, Government Thiruvarur Medical College, Thiruvarur, India
2Reader, 3PG trainee ,4Senior lecturer, Department of Oral Medicine, Diagnosis and Radiology, ThaiMoogambigai Dental College and hospital, Chennai-107, India
*Correspondence to:-
Dr. Sridhar. C, MD
Associate professor of medicine,Department of internal medicine, Government Thiruvarur medical college, Thiruvarur, India.
Contact number: 09884664502
Abstract:
Pemphigus is an uncommon, potentially fatal, autoimmune disorder characterized by intra-epithelial bullae on the skin and mucous membranes. Pemphigus is a chronic ulcerative lesion, with intra oral lesions often preceding the skin lesions in majority of the patients. Most of the patients are initially misdiagnosed and improperly treated for months, which in turn complicates disease control. Since physicians have the opportunity to examine the oral cavity frequently and are often the first to be consulted for oral complaints, they are required to be familiar with the clinical presentation of Pemphigus, in order to contribute towards early diagnosis and thereby improve the chance of prolonged remission at a lower drug dosage for a shorter period of time.
We report one such case of intra oral pemphigus in a 37-year old female patient, which was misdiagnosed at its earlier stage for nearly 6 months. The patient responded very well to a short course of systemic corticosteroids and remains disease-free during the one year follow-up period. This paper highlights the importance of diagnosing any chronic ulcerative lesions by thorough investigations, including a prompt biopsy so as to arrive at proper diagnosis and management, to enhance the prognosis and thereby reduce the morbidity and mortality rate.
Key words: Autoimmune; Erosions; Oral cavity; Pemphigus.
REFERENCES
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Article citation:
Sridhar. C et al. Oral Pemphigus :- An underdiagnosed and misdiagnosed entity. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) May(Supplement 1);30(30):S72-S75. Available at http: //www.jpbms.info
Copyright © 2013 Sridhar. C et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Review article
Ravleen Kaur1, Inderjot Singh2, Gina Singh3, Anushi Mahajan4
Affiliation:-
1Assistant Professor, Department of Periodontics, Christian Dental College, Ludhiana, Punjab, India.
2Associate Professor, Department of Oral & Maxillofacial surgery, Christian Dental College, Ludhiana, Punjab, India.
3Professor and Head, Department of Periodontics, Christian Dental College, Ludhiana, Punjab, India.
4Assistant Professor, Department of Periodontics, Christian Dental College, Ludhiana, Punjab, India.
*Correspondence to:-
Dr Ravleen Kaur
Assistant Professor, Department of Periodontics,
Christian Dental College, Ludhiana, Punjab, India
Phone no:- +91-09781108811
Abstract:
Dental professionals have addressed the increased challenge of infectious disease and infection control by emphasizing seven major areas; aseptic technique, patient screening and evaluation, personal protection, instrument sterilization, environmental surface disinfection, equipment asepsis and laboratory asepsis. Each infection control component contributes to minimizing the potential for cross-infection during provision of dental treatment. Dental patients fall into several risk categories concerning the transmission of infection. Some patients will only suffer from dental or oral diseases, others are infected, some are healthy carriers, and yet others are symptomatic or asymptomatic carriers of a transmissible disease at a contagious or noncontiguous stage.
Key words: Periodontal aerosol; dental aerosol; bioaerosols.
References:
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Article citation:-
Ravleen Kaur, Inderjot Singh, Gina Singh, Anushi Mahajan. Aerosols a menace for the dental healthcarers. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) May(Supplement 1); 30(30):S58-S62. Available at http: //www.jpbms.info.
Copyright © 2013 Ravleen Kaur, Inderjot Singh, Gina Singh, Anushi Mahajan. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Review article
*1G. Sree Vijayabala,2Anupama N. Kalappanavar,3Rajeshwari G Annigeri,
4 Ramachandran Sudarshan
Affiliation:-
1Assistant Professor in Dentistry, ESIC Medical College and PGIMSR,KK Nagar, Ashok Pillar road, Chennai, India.
2Professor,3Professor and Head, Department of Oral Medicine and Radiology, College of Dental Sciences, Davanagere, Karnataka, India.
4Senior Lecturer, Department of Oral Medicine and Radiology, Best Dental Science College, Madurai, Tamilnadu. India.
Author’s contributions-All authors contributed equally to this paper.
Abstract:
Recurrent aphthous ulcers are painful ulcers of the oral mucosa that affects individuals’ atleast once in their lifetime. `An effective therapeutic strategy for aphthous ulcer must address both pain reduction as well as ulcer healing. Many therapies have been advocated from the past for efficacious management of these ulcers but no therapy available to date has been validated as gold standard for the management of aphthous ulcers. This review elucidates in brief about the past and current concepts in the management of aphthous ulcers.
Key words: Recurrent aphthous stomatitis; Ulcer; Management.
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Article citation:-
G. Sree Vijayabala,Anupama N. Kalappanavar, Rajeshwari G Annigeri,Ramachandran Sudarshan.. Past and present concepts in the management of recurrent aphthous ulcers: a review. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 May (Supplement); 30(30):S40-S49.Available at http://www.jpbms.info.
Copyright © 2013 G. Sree Vijayabala,Anupama N. Kalappanavar,Rajeshwari G Annigeri,Ramachandran Sudarshan. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article
Edet, E. E.*, Adewuni Daniel & Uti, D. E.,
Affiliation:-
Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medical Sciences, University of Calabar, P. M. B.1115, Calabar – Nigeria.
Abstract:
The potential neurotoxic and nephrotoxic effects following oral administration of ethanolic leaf extract of anacardium occidentale (cashew) were investigated in Wistar albino rats. Twenty (20) male albino Wistar rats weighing 100-160g were divided into five groups of four rats each. Groups 2, 3 and 4 were respectively gavaged with 500mg/kg, 1000mg/kg and 2000mg/kg body weights of the extract daily for 21 days while group 1 and 5 served as pre and post controls respectively. At the end of treatments, animals were sacrificed; brain and kidney tissues were obtained. The tissues were histologically processed and stained using Haematoxylin and Eosin technique. Stained tissues sections were examined microscopically using a light bionocular microscope. The results show that treatment of rats with the respective doses of the extract did not cause any visible degenerative change in the brain and kidney in all test groups. The brain and kidney architectures were well preserved in all the treatments groups. This result suggests that ingestion of the extract is non-toxic to the brain and kidney at the doses investigated.
Key Words: Anacardium occidentale leaves, brain, kidney, histoarchitecture, ethanolic extract, rat.
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Article citation:-
Edet, E. E, Adewuni, D. & Uti, D. E. Effect of ethanolic leaf extract of Anacardium occidentale on histoarchitecture of brain and kidney. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013, May (Supplement 1); 30(30): S31-S35.Available at http://www.jpbms.info.
Copyright © 2013 Edet, E. E, Adewuni, D & Uti, D. E. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Case report:-
Archana Wankhade1*,Dnyaneshwari Ghadage2, Arvind Bhore2& Shripad Bhat3
Affiliation:-
*1Assistant Professor, 2Professor, Department of Microbiology, 3Associate Professor, Department of Medicine Smt Kashibai Navale Medical College and Hospital, Narhe, Pune-411041,India.
Abstract:
Tuberculosis is a generalized disease most commonly localized in the pulmonary system. Chronic disseminated tuberculosis is defined as the disease prolongs and involves several organs of the body. Rarely there may be Chronic dissemination of tuberculosis in various extrapulmonary sites for which culture is required for firm diagnosis.
Case:- A 23 year old thin build female patient visited the OPD to rule out the cause of infertility. The patient had past history of tuberculosis for which the treatment had been completed. After diagnostic laproscopy, ascitic fluid was submitted in Microbiology. Mycobactererium tuberculosis was isolated by Bact/Alert 3D and antitubercular drug sensitivity was done by proportion method. The patient was treated with CAT II drugs under RNTCP. With the gap of 6 months the patient presented with cervical lymphadenopathy and pleural effusion. Lymph node biopsy tissue was sent in Microbiology laboratory for the Mycobacterial culture. Mycobacterium tuberculosis was isolated by Bract/Alert 3D automated system. Both the specimens were negative for culture on LJ by conventional method.
In conclusion, our patient presented with a group of uncommon extrapulmonary presentation including abdominal involvement with associated cervical lymphadenopathy without any immunodeficiency context but not responding to antitubercular drugs. The firm diagnosis was made by culture.
Key words: Dissiminated TB, extrapulmonary TB.
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Article citation:-
Archana Wankhade, Dnyaneshwari Ghadage, Arvind Bhore & Shripad Bhat. Chronic disseminated tuberculosis: A case report. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 May (Supplement 1); 30(30): S28-S30.Available at http://www.jpbms.info
Copyright © 2013 Archana B Wankhade. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.