DocumentsDate added
Research article
*1Aremu.Ademola Adegoke ,2Atanda Oluseyi Olaboyede & 3Adeomi. Adeleye Abiodun
Affiliation:-
1Radiology Department,2Obstetrics and Gynaecology,3Community Medicine Department, Ladoke Akintola University of technology teaching hospital, Ogbomoso.Oyo state. Nigeria.
Abstract:
Background: The aim of this study was to determine the predictability of the birth weights of newborns by ultrasound measurement of placental thickness, to assess the relationship between ultrasound placental thickness with weight and volume of placental after delivery and relate (the weight and volume) to the birth weight.
Method: A cross sectional study of three hundred consecutive singleton pregnancies that were scanned between 36weeks gestation and delivery.
The placental thickness measured prenatally with Ultrasound was then compared and related with/to physical measurements of placental weight, volume and birth weight at delivery.
Results: 2D prenatal ultrasound measurement of placental thickness is a true reflection of the actual placental weight and volume and a positive predictor of the birth weight. A thickness less than 20mm is statistically associated with low birth weight.
Conclusion: Ultrasonic assessment of placental thickness and grading can accurately predict the actual placental weight and volume and also predict subsequent occurrence of fetal growth retardation and low birth weight infants.
Key Words: Placental thickness, placental weight, placental volume, Birth weight.
Article citation:-
Aremu Ademola Adegoke ,Atanda Oluseyi Olaboyede & Adeomi Adeleye Abiodun. Newborn birth weight and placental parameters in normal human pregnancies. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 May (Supplement 1); 30(30): S23-S27.
Copyright © 2013 Aremu Ademola Adegoke ,Atanda Oluseyi Olaboyede & Adeomi Adeleye Abiodun This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article:-
*1Mohaned M. Mohammed, 2 Sania A. I. Shaddad, 3Abd Elkhalig Mudathir, 4Elsharif B.A & 5A. Afaf E. Abu Algasem
Affiliation:-
1Pharmacology Lecturer, AlNeelain University & Elrazi College for Medical and Technological Sciences, Sudan.
2Associate professor of pharmacology, Faculty of Medicine, University of Khartoum, Algassar street, Khartoum, Sudan.
3Associate professor of pharmacognosy, Faculty of Pharmacy, University of Khartoum, Algassar street, Khartoum, Sudan.
4Assistant Professor of Artificial insemination, Animal Genetic Resources Development Administration (Kuku, Khartoum North),Sudan.
5Proffesor of pathology, Faculty of Veterinary Medicine, University of Khartoum, University of Khartoum, Algassar street,, Khartoum, Sudan.
Abstract:
Introduction: Tribulus terrestris is a member of the Zygophyllaceae family. It is widely distributed in Africa, western Asia, China, Japan, Korea and Europe.
Tribulus terrestris is used in the folk medicine of India, China, Bulgaria and South Africa against sexual impotence, edemas, abdominal distention and cardiovascular diseases. It has been used since ancient times as an aphrodisiac as well as to treat urinary infections, inflammation, and other ailments. It also exhibits anthelmintic activity.
Tribulus terrestris may be useful in mild to moderate cases of erectile dysfunction . It has been shown to increase the free serum testosterone.
Objectives: Evaluation of the phytochemical screening of Tribulus terrestris extract, study the effects of the extract on serum testosterone level and semen quality.
Material and Methods: Extraction of Tribulus terrestris fruits was carried out according to standard method. Two different groups of adult male rats and two of cocks were used. Group1 rats and cocks served as control, while group 2 received Tribulus terrestris (TT) crude extract 7.5 mg\kg\day orally. Total serum testosterone was measured in rats before, after two and four weeks of treatment. Cocks semen was collected by dorso-abdominal massage (standard method) and evaluated before treatment, after two and four weeks of treatment.
Results: Preliminary phytochemical screening of Tribulus terrestris fruits ethanolic extract showed the presence of high concentrations of coumarins and flavonoids, various concentrations of tannins, triterpenses and saponins and absence of anthraquinone glycoside compounds, alkaloids and sterols.
Tribulus terrestris fruits ethanolic extract insignificantly (p > 0.05) increased serum testosterone concentration in the treated rats and significantly (p < 0.05) increased the sperm concentration in cocks, also insignificantly (p > 0.05) increased both mass and individual sperm motility of the treated cocks. Histopathological examination of the rat’s testes treated with Tribulus terrestris fruit ethanolic extract showed marked activity of spermatogenesis in the seminiferous tubules.
Conclusion: The study showed that Tribulus terrestris fruits extract can improve male fertility by increasing the sperms concentration, testosterone concentration and stimulating the mass and individual motility of the sperms.
Key Words: Tribulus terrestris; Fertility; Rats;Cocks.
References:
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17.A Adimoelja, L Setiawan, and T Djojotananjo. Tribulus terrestris (protodioscin) in the treatment of male infertility with idiopathic oligoasthenoterato-zoospermia. University, Surabaya, Indonesia in First International Conference of Medical Plants for Reproductive Medicine in Taipei, Taiwan (1995).
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20.Neychev VK, Mitev VI.The aphrodisiac herb Tribulus terrestris does not influence the androgen production in young men.J Ethnopharmacol. 2005 Oct 3;101(1-3):319-23.
Article citation:
Mohaned. M. M et al. Effects of Tribulus terrestris ethanolic extract in male rats & cocks fertility. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 May (Supplement 1); 30(30): S13-S18.
Copyright © 2013 M.M.Mohaned et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article:-
*1Parmar Sanjay & 2Aakansha Jalwal
Affiliation:-
1Associate Professor, Department of Physiotherapy, SDM College of Medical Sciences and Hospital, Dharwad, Karnataka, India.
2MPT (Ped), Consultant paediatric physiotherapist, Saket, New delhi, India.
Abstract:
Objectives: Childhood obesity is a chronic pediatric disease with possible complication. There is a reduction in natural physical activity levels and with increase in sedentary life style among children. Various forms of exercise are effective and helpful in obesity management. As limited evidence been found on obesity using resistance exercise so this study was carried out to study the effectiveness of resistance training in overweight and obese adolescents.
Design: Experimental Design:
Methods: A sample of 25 subjects between ages of 10 to 16 years was obtained from outpatient department of Physiotherapy, SDM College of Medical Sciences and Hospital, Dharwad. The study duration was one year. The study was briefly explained to parents / guardian of children diagnosed to have overweight / obesity and written consent was obtained. Routine evaluation including demographic data, BMI, Waist Circumference and Waist Hip Ratio was calculated pre and post interventions. The intervention was done for 45 minutes for 3 days per week for 12 weeks. Adolescents were engaged in a structured practice during the intervention. The appropriate warm up and cool down exercise were given before and after the individualized resistance exercise program.
Results: Results showed a reduction in outcome measures with pre and post values p= 0.000.
Conclusion: Resistance training showed effective reduction of overweight and obesity in adolescents.
Key Words: Overweight, Obesity, Resistance, Adolescents.
References:
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2.Amanda JD, Robert JC, Neil PW, Andrea R, Jerry KW. Exercise therapy as a treatment for psychopathologic conditions in obese and morbidly obese adolescents- a randomized controlled trail. Pediatrics Nov 2006;118( 5).
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4.National Health and Medical Research Council. Clinical practice guidelines for the management of overweight and obesity in children and adolescents. Canberra: NHMRC, 2003. Available from: URL: www.health.gov.au/internet/wcms/publishing.nsf/content/obesity guidelines-guidelines-children.htm/$FILE/children.pdf (assessed Nov 2004).
5.Avery D Faigenbaum. Resistance Training for Obese Children and Adolescents. Research Digest 2007 Sep Series 8(3).Available from: URL: http://ajl.sagapub.com/cgi/content/abatract/1/3/190.
6.Wayne L Westcott. Childhood Obesity Available from: URL:https://www.nsca- lift.org/HotTopic/download/Childhood%20Obesity%20With%20Logo.pdf
7.Avery D Faigenbaum. Resistance Training for Obese Children and Adolescents. Research Digest 2007 Sep Series 8(3).Available from: URL: http://ajl.sagapub.com/cgi/content/abatract/1/3/190.
8.Jack H Wilmore, David L Costill. Physiology of Sports and Exercise. 3ed. Hong Kong: Human Kinetics; 2004; 500-30.
9.William Mc Cardle, Frank I Katch, Victor L Katch. Exercise Physiology: Energy Nutrition and Human Performance. 7th ed. USA: Lippincott Williams and Wilkins; 1996; 780-824.
10.Dan Nemet, Sivan Barkan, Youram epstein, Orit Friedland, Galit Kowen, Alon Eliakim. Short and long term beneficial effect of a combined dietary-behavioral-physical activity intervention for the treatment of childhood obesity. Pediatrics April 2005; 115(4).
11.Supreet Kaur, Umesh Kapil and Preeti Singh. Pattern of chronic diseases amongst adolescent obese children in developing countries. Curr Sci Apr 2005;88:7-10.
12.M Premnath, H Basavanagowdappa, MA Shekar, SB Vikram and D Narayanappa. Mysore Childhood Obesity Study. Ind Paediatr 2009 Apr.
13.Mary Jean Taylor, Margaret Mazzone and Brain H. Wrotniak. Outcome of an exercise and educational intervention for children who are overweight. Pediatr Phys Ther 2005;17:180-8.
Article citation:
Parmar Sanjay & Aakansha Jalwal. To study the effectiveness of resistance training in overweight and obese adolescents. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 May(Supplemet 1); 30(30):S19-S22.
Copyright © 2013 Parmar Sanjay & Aakansha Jalwal. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Case report
Sridhar. C1,Krithika. C2,Uma Maheswari. S3,Ponni. V4,Praveena. NM4,PriyaRamani2.
Affiliation:-
1Associate Professor of Medicine, Department of Internal Medicine, Government Thiruvarur Medical College, Thiruvarur, India
2Reader, 3PG trainee ,4Senior lecturer, Department of Oral Medicine, Diagnosis and Radiology, ThaiMoogambigai Dental College and hospital, Chennai-107, India
*Correspondence to:-
Dr. Sridhar. C, MD
Associate professor of medicine,Department of internal medicine, Government Thiruvarur medical college, Thiruvarur, India.
Contact number: 09884664502
Abstract:
Pemphigus is an uncommon, potentially fatal, autoimmune disorder characterized by intra-epithelial bullae on the skin and mucous membranes. Pemphigus is a chronic ulcerative lesion, with intra oral lesions often preceding the skin lesions in majority of the patients. Most of the patients are initially misdiagnosed and improperly treated for months, which in turn complicates disease control. Since physicians have the opportunity to examine the oral cavity frequently and are often the first to be consulted for oral complaints, they are required to be familiar with the clinical presentation of Pemphigus, in order to contribute towards early diagnosis and thereby improve the chance of prolonged remission at a lower drug dosage for a shorter period of time.
We report one such case of intra oral pemphigus in a 37-year old female patient, which was misdiagnosed at its earlier stage for nearly 6 months. The patient responded very well to a short course of systemic corticosteroids and remains disease-free during the one year follow-up period. This paper highlights the importance of diagnosing any chronic ulcerative lesions by thorough investigations, including a prompt biopsy so as to arrive at proper diagnosis and management, to enhance the prognosis and thereby reduce the morbidity and mortality rate.
Key words: Autoimmune; Erosions; Oral cavity; Pemphigus.
REFERENCES
1.Ljubojević S, Lipozenčić J, Brenner S, Budimčić D. Pemphigus vulgaris: a review of treatment over a 19‐year period. Journal of the European Academy of Dermatology and Venereology 2002;16(6):599-603.
2.Anhalt GJ, Diaz LA. Prospects for autoimmune disease: Research advances in pemphigus. JAMA 2001;285(5):652-4.
3.Moraes ME, Fernandez-Vina M, Lazaro A, et al. An epitope in the third hypervariable region of the DRB1 gene is involved in the susceptibility to endemic pemphigus foliaceus (fogo selvagem) in three different Brazilian populations. Tissue Antigens 1997;49(1):35-40.
4.Dagistan S, Goregen M, Miloglu O, Cakur B. Oral pemphigus vulgaris: a case report with review of the literature. J Oral Sci 2008;50(3):359-62.
5.Ruocco E, Baroni A, Wolf R, Ruocco V. Life-threatening bullous dermatoses: Pemphigus vulgaris. Clin Dermatol 2005;23(3):223-6.
6.Toth GG, Jonkman MF. Therapy of pemphigus. Clin Dermatol 2001;19(6):761-7.
7.Neville B.W, Damm D.D, Allen C.M, J.E. B. Oral & maxillofacial pathology. 2nd ed. Philadelphia: Saunders 2002:664-7.
Article citation:
Sridhar. C et al. Oral Pemphigus :- An underdiagnosed and misdiagnosed entity. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) May(Supplement 1);30(30):S72-S75. Available at http: //www.jpbms.info
Copyright © 2013 Sridhar. C et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Case report:-
Archana Wankhade1*,Dnyaneshwari Ghadage2, Arvind Bhore2& Shripad Bhat3
Affiliation:-
*1Assistant Professor, 2Professor, Department of Microbiology, 3Associate Professor, Department of Medicine Smt Kashibai Navale Medical College and Hospital, Narhe, Pune-411041,India.
Abstract:
Tuberculosis is a generalized disease most commonly localized in the pulmonary system. Chronic disseminated tuberculosis is defined as the disease prolongs and involves several organs of the body. Rarely there may be Chronic dissemination of tuberculosis in various extrapulmonary sites for which culture is required for firm diagnosis.
Case:- A 23 year old thin build female patient visited the OPD to rule out the cause of infertility. The patient had past history of tuberculosis for which the treatment had been completed. After diagnostic laproscopy, ascitic fluid was submitted in Microbiology. Mycobactererium tuberculosis was isolated by Bact/Alert 3D and antitubercular drug sensitivity was done by proportion method. The patient was treated with CAT II drugs under RNTCP. With the gap of 6 months the patient presented with cervical lymphadenopathy and pleural effusion. Lymph node biopsy tissue was sent in Microbiology laboratory for the Mycobacterial culture. Mycobacterium tuberculosis was isolated by Bract/Alert 3D automated system. Both the specimens were negative for culture on LJ by conventional method.
In conclusion, our patient presented with a group of uncommon extrapulmonary presentation including abdominal involvement with associated cervical lymphadenopathy without any immunodeficiency context but not responding to antitubercular drugs. The firm diagnosis was made by culture.
Key words: Dissiminated TB, extrapulmonary TB.
References:
1.Sharma, S.K., Mohan, A., Prasad, K.L., et al. Clinical profile, laboratory characteristics and outcome in miliary tuberculosis. QJM 1995; 88:29-37.
2.Stephanie C. Andres, M.D. and Angeles Tan-Alora, A Case Series on Disseminated Tuberculosis Phil J Micro Infect Dis 2001; 30(1):29-35.
3.Verver S,Warren R,Richardson M,Spuy G,Martien W,Borgodorff,E .Donald. Rate of reinfection tuberculosis after successful treatment is higher than rate of new tuberculosis. Am J. Resp. Crit. Care. Med 2005; 171 (12):1430-5.
4.Richardson M,Carroll N ,Erica E ,Spuy G, Salker F, Munch Z, Multiple mycobacterium tuberculosis Micro strains in early cultures from patients in high incidence communbiol 2002;40(8):2750-4.
Article citation:-
Archana Wankhade, Dnyaneshwari Ghadage, Arvind Bhore & Shripad Bhat. Chronic disseminated tuberculosis: A case report. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 May (Supplement 1); 30(30): S28-S30.Available at http://www.jpbms.info
Copyright © 2013 Archana B Wankhade. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.