DocumentsDate added
Short communication
*1Hinduja Dharam, 2 Muthu Karuppaiah. R, 3 MN Vishwanath, 4 Babaji Prashant & 5 DMello Kuldeep
Affiliation:
1Associate Professor, Department of Conservative Dentistry & Endodontics, Index Dental College, Indore, Madhya Pradesh, India.
2Reader, Department of Community Dentistry, Rajah Muthai Dental College, Chidamberam, Tamilnadu, India.
3Professor, Department of Orthodontics, Sharavathi Dental College, Shimoga, Karnataka, India.
4Associate Professor,Department of Pedodontics, Vyas Dental College, Jodhpur, India.
5Professor, Department of Orthodontics, Vyas Dental College, Jodhpur-342001, Rajasthan, India.
Abstract:
Nanorobotics technology is an area of science which refers to designing and building nanorobotic device ranging from 0.1 to 10 mm. This technology is used in both medicine and dentistry for tooth renaturalisation, orthodontics teeth alignment, for local anesthesia, diagnosing and treating the disease.
Key words: Nano dentistry; nano technology; nano medicine.
REFERENCES
1.Ravindran R. Nano technology in cancer diagnosis and treatment: An overview. Oral and maxillofacial Pathology Journal. 2011;2(1): 101-105.
2.Mouli CPe, Kumar MS, Parthiban S. International Journal of Biological & medical Research. 2012; 3(2): 1550-1553.
3.Bhvaneswarri J, Alam N, chandrashekaran SC, Sathya MS. Future impact of nanotechnology in Dentistry-A review. 2013;3(2):15-20.
4.Verma SK, Chauhan R. Nanorobotics in dentistry-A review. Indian Journal of Dentistry. 20-13;1-9.
5.Shetty NJ, Swati P, David K. Nanorobotics:Future in dentistry. 2012;25:49-52.
6.Rybachuk AV, Nebesna T Yu. Nanotechnology and nanoparticles in Dentistry. Pharacology and Pharmaceutics.2009;18-21.
Article citation:-
Hinduja D et al. Nano dentistry: A boon to dentistry. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 September; 34(34): 1654-1656. Available at http://www.jpbms.info
Copyright © 2013 Hinduja D et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Sinha Abhishek1*,Srivastava Sunita2, Mishra Anuj3, Agarwal Nitin4 & Pooja M. Sinha5
Affiliation:-
1Reader,2Senior Lecturer, 3Post graduate student, 4Professor & Head, Department of Oral Medicine and Radiology, 5Senior lecturer, Department of public health dentistry, Sardar Patel Post Graduate Institute of Dental & Medical Sciences, Raebareily Road, Lucknow, Uttar Pradesh, India.
Author’s contributions:- All the authors contributed equally to this paper.
Work attributed by: Department of Oral Medicine and Radiology, Sardar Patel Post Graduate Institute of Dental & Medical Sciences, Raebareily Road, Lucknow, Uttar Pradesh, India.
Abstract:
Background: Oral Lichen planus is a chronic inflammatory disorder that can be painful especially in erosive forms that commonly affects skin and oral mucosa. In this area different treatments have been used in symptomatic oral lichen planus (OLP), with variable results.
Aim: To compare the efficacy of aloevera and topical steroids in symptomatic treatment of Erosions and burning sensation in Erosive Lichen Planus.
Methods: A total of 10 patients with Oral Lichen Planus were randomly selected for the study and divided into two groups (A and B). The group A received aloe vera gel and group B topical steroids. The patients were under regular follow up every 2 weeks for 3 months. Clinical evaluation and pain reduction was evaluated by VAS method in group A and B. Data were evaluated statistically by using Wilcoxon signed rank test.
Results: In group A, 4 patients had complete remission and 1 patient showed good response to treatment where as in group B, 2 patients had complete remission, 2 patient showed good response and 1 patient showed no response to treatment (p<0.001), it was determined that Aloevera was stastistically significant (p<0.05) as compared to Topical Steroid at the end of treatment.
Conclusion: The topical application of Aloe vera improves the total quality of life score in patients with oral lichen planus. However, according to result of this study, the use of aloevera gel instead of steroid in treating erosive lichen planus is better and more appropriate choice.
Key words: Aloevera gel; Burning sensation; Oral lichen planus; Triamcinolone acetonide.
REFERENCES
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15.Davis RH, Joseph JD, Donato D, Hartman GM, Haas RC. Inflammatory and Wound Healing Action of Aloe Vera. Hightstown: Mettler Instrument, 1994:77–81.
Article citation:-
Sinha Abhishek,Srivastava Sunita, Mishra Anuj, Agarwal Nitin & Sinha M Pooja. Aloevera vs topical steroid in treatment of erosive lichen planus. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 September; 34(34): 1657-1662.Available at http://www.jpbms.info
Copyright © 2013 Sinha Abhishek,Srivastava Sunita, Mishra Anuj, Agarwal Nitin. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
AnkolekarVrinda H1*,Quadros Lydia S2 & D’souza Antony S3
Affiliation:-
1MD Anatomy, 2M.Sc. (Medical), 3MS Anatomy, Department of Anatomy, Kasturba Medical College, Manipal University, Manipal – 576104, Karnataka, India.
Author’s contributions:- AnkolekarVrinda H contributes towards concept, design, literature search, clinical studies, data acquisition, statistical analysis, manuscript writing and editing. Quadros Lydia S helps in literature search, data analysis, manuscript editing, and writing. D’souza Antony S analysed, collected the data and helped in manuscript writing.
The name of the Department and Institution to which the work should be attributed:-
Department of Anatomy, Kasturba Medical College, Centre for Basic Sciences, Manipal University. Madhavnagar, Manipal – 576104, Karnataka, India.
Abstract:
Background: Knowledge of the coronary venous system (CVS) anatomy is an important factor before many electrophysiological procedures, such as CRT or ablations.
Aim: To study the anatomy of the coronary venous system and its tributaries in cadaveric hearts.
Methodology: Fifty-five normal formalin-fixed adult human cadaveric hearts were used in this study. The following measurements were noted: a. length of coronary sinus, b. its relation to left coronary artery, mitral valve annulus and left atrium, c. number of atrial and ventricular tributaries, d. distance and the opening angles of major tributaries from the coronary ostium, e. length and width of coronary ostium, f. Attachment of Thebesian valve.
Results:
a.Length of coronary sinus(CS) ranged from 2cm to 3.8cm, the mean being 2.8cm.
b.Relation of coronary sinus to the left coronary artery (LCA) andmitral valve annulus was above and parallel in 100% cases.
c.The number of Atrial tributariesranged from 1-2 and ventricular from 1-6.
d.The mean distance ofAnterior interventricular vein (AIV),Posterior vein of the left ventricle (PVLV),Oblique vein of left atrium (OVLA),Middle cardiac vein (MCV) from the coronary ostium was 67.5mm, 32mm, 41mm, 7mm respectively.
e.The average length and width of coronary ostium was 9mm and 13mm respectively.
f.The besian valve in 24/55 hearts was attached to the superior, right and inferior margins of the ostium. In 29/55 hearts to the inferior margin of the ostium.
Conclusion: For invasive cardiologists, knowledge about CVS anatomy could add value before and during electrophysiology procedures.
Key Words: Coronary sinus; coronary ostium; great cardiac vein; the besian valve.
REFERENCES
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Article citation:-
AnkolekarVrinda H, Quadros Lydia S & D’souza Antony S. Morphometric and morphological variations of coronary venous system and its tributaries – An anatomical study. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 September; 34(34): 1663-1669.Available at http://www.jpbms.info
Copyright © 2013 AnkolekarVrinda H,Quadros Lydia S & D’souza Antony S. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article
1Varsha Chaudhary, *2Bhat Kishore,3Sunil Rao,4Preeti Ingalagi & 5Manohar Kugaji
Affiliation:-
1,5Research Officer,2Professor and Head,4Sr. Lecturer, Department of Microbiology, Maratha Mandal’s NGH Institute of Dental Sciences and Research Centre, Belgaum, Karnataka, India.
3Professor and Head, Department of Microbiology, Yenepoya Medical College, Yenepoya University, Mangalore, India.
Author’s contributions: - All the authors contributed equally to this paper.
The name of the Department and Institution to which the work should be attributed:-
Department of Microbiology,
Maratha Mandal’s NGH Institute of Dental Sciences And Research Center, Near K.S.R.P .Ground, R.S.No.47/2, Bauxite Road
Belgaum. (Karnataka), India.
Abstract:
Porphyromonas gingivalis is a major member of red complex in the oral cavity and play a significant role in the progression of adult periodontitis charecterized by alveolar bone loss. Variety of methods such as culture, PCR, Microscopy etc. has been used to detect P.gingivalis but each one has distinct advantages and disadvantages. PCR assays with synthesized 16S r RNA probes enable the detection of virtually any microorganism in a plaque sample. This technique, therefore, is the most sensitive of any of the above.
Aim: To compare culture technique and PCR method to detect and quantify P.gingivalis in subgingival plaque samples in order to assess the relationship of this bacterium with periodontal status.
Materials & Methods: A total of one hundred patients with adult periodontitis and an equal number of controls were selected in an age range of 20 to 50 years and belonged to both the sexes. Sub gingival plaque samples were collected and subjected to anaerobic culture and PCR. In culture species identification was done based on biochemical reactions. The PCR was performed by using specific primers for the 16S rRNA gene of P. gingivalis and quantification was done using standard strain of P.gingivalis.
Results: Comparison was done between the results of anaerobic culture & PCR for control and chronic periodontitis patients. Statistically P value <0.001 is significant & kappa statistics demonstrated moderate agreement (K=0.554) between the above two groups. Results of culture and PCR also depicted that female were prone to chronic periodontitis than male in all the age groups.
Conclusion: The result of PCR confirms those of quantitative culture of P.gingivalis, and offers significant advantages with respect to the rapidity and sensitivity of detection of P.gingivalis in sub gingival plaque samples.
Key Words: Culture; PCR; P.gingivalis; red complex.
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Article citation:-
Varsha Chaudhary, Bhat Kishore, Sunil Rao, Preeti Ingalagi & Manohar Kugaji. Comparison of culture and PCR for detection of Porphyromonas gingivalis in patients with chronic periodontitis and healthy subjects. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 September; 34(34): 1670-1675.Available at http://www.jpbms.info
Copyright © 2013 Varsha Chaudhary, Bhat Kishore, Sunil Rao, Preeti Ingalagi & Manohar Kugaji. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article
Aiyalu Rajasekaran1*, Ramasamy Arivukkarasu2 & Shanmugasundaram Murugesh3
Affiliation:-
1KMCH College of Pharmacy, Coimbatore- 641 048, Tamilnadu, India.
2Research scholar, SASTRA University, Thanjavur-613401, Tamilnadu, India.
3Periyar University, Salem, Tamilnadu, India.
Author’s contributions: - All the authors contributed equally to this paper.
The name of the Department and Institution to which the work should be attributed:-
KMCH College of Pharmacy, Coimbatore- 641 048, Tamilnadu, India.
Abstract:
Background: Ethno medical studies of north Gujarat (India) reveal the use of hot aqueous extract of Adenema hyssopifolium by tribal inhabitants for the treatment of diabetes, fever, stomach ache, dyspepsia and for malaria in interior part of Gujarat. Traditional siddha practitioners of Tamilnadu use this processed fortified powder of this plant, by dispensing along cumin’s for jaundice patients, two grams two times a day, advised to take this herbal powder and along with cooked fermented rice water to cure the jaundice.
Objective: The purpose of the study is to evaluate In vitro antioxidant activity of the ethanol extract of Adenema hyssopifolium to scientifically validate and support the traditional claim.
Materials and methods: In vitro assessment was carried out by DPPH, nitric oxide radicals, hydrogen peroxide and superoxide scavenging activity. Results: Ethanol extract exhibited 71%, 70% and 81% of scavenging activity in DPPH method (IC50=540 µg/mL), superoxide ((IC50=715 µg/mL) and hydrogen peroxide method ((IC50=760 µg/ml) respectively. Ascorbic acid 98% (IC50=540 µg/ml), Quercetin 85% (IC50=715 µg/ml) and Butylated hydroxy toluene 95% (IC50=640 µg/ml) were used as reference standards respectively. Total flavonoid and phenol content in ethanol extract of Adenema hyssopifolium was found to be 0.37% equivalent to Quercetin and 1.29% equivalent to Gallic acid respectively.
Conclusion: Ethanol extract showed potential antioxidant and free radical scavenging activity, which may be due to the presence of flavonoid and iridoid glycosides in the Adenema hyssopifolium extract.
Key Words: Adenema hyssopifolium; antioxidant; iridoid glycoside.
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Article citation:-
Aiyalu Rajasekaran, Ramasamy Arivukkarasu & Shanmugasundaram Murugesh. In-vitro antioxidant activity of ethanol extract of Adenema hyssopifolium G.Don. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 September; 34(34): 1676-1681.Available at http://www.jpbms.info
Copyright © 2013 Aiyalu Rajasekaran, Ramasamy Arivukkarasu & Shanmugasundaram Murugesh. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.