DocumentsDate added
Review article
Rachna Jain1*, Kumud Mittal2 & Shekhar Kapoor3
Affiliation:-
1MDS, Senior lecturer, Department of Periodontics and Implantolgy, SKSS Dental College and Hospital, Ludhiana, Punjab, India
2MDS, Reader, Department of Oral Medicine and Radiology, SKSS Dental College and Hospital, Ludhiana, Punjab, India
3MDS, Associate professor, Department of Oral Medicine and Radiology, Christian Dental College and Hospital, Ludhiana, Punjab, India
Author’s contributions-
The credit for the concept and idea behind the article design goes to the first author. Collection of the whole data and the literature search has been done by all three authors. Editing of the whole manuscript has been done by first and third author.
The final refining of the script has been done by all three authors.
Corresponding Authors
Dr. Rachna Jain.
MDS, Senior lecturer, Department of Periodontics and Implantolgy, SKSS Dental college and hospital, Ludhiana, Punjab, India
Core Idea:- Aac is one of the most important periodontopathogen. Not much has been written about the virulence factors lately. So the idea of the review was to signify its virulence factors and the role it plays in causing periodontal disease.
Abstract:
Periodontitis patients are a heterogeneous group of individuals with diverse genetic backgrounds, systemic and psychological conditions and varied clinical manifestation. Evidence show that A. actinomycetemcomitans is able to elicit its own uptake into epithelial cells and its spread to adjacent cells by usurping normal epithelial cell function.
A. actinomycetemcomitans has individual factors that cause bone resorption, as well as a number of activities that elicit detrimental effects on connective tissue and the extracellular matrix. In this short review the invasiveness and the virulence of A. actinomycetemcomitans comitans are discussed. Factors that promote A. actinomycetemcomitans colonization and persistence in the oral cavity include adhesins, bacteriocins, invasins and antibiotic resistance. It can interact and adhere to all components of the oral cavity (the tooth surface, other oral bacteria, epithelial cells or the extracellular matrix). The adherence is mediated by a number of distinct adhesins that are elements of the cell surface (outer membrane proteins, vesicles, fimbriae or amorphous material).
Key words: A.actinomycetemcomitans, virulence factors, epithelial cells, periodontal disease.
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Article citation:-
Rachna Jain,Kumud Mittal& Shekhar Kapoor. Virulence factors of A. actinomycetemcomitans – A review. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 September 34(34): 1693-1698.
Copyright © 2013 Rachna Jain,Kumud Mittal & Shekhar Kapoor. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
*1Abbas, Israa, M. &2El hag, Wafa, I,PhD.
Affiliation:-
1MSc. Student, Faculty of Medical Laboratory Sciences-AL-Neelain University, Khartoum, Sudan.
2Assistant professor, Microbiology department, Faculty of Medical Laboratory Sciences-AL-Neelain University, Khartoum, Sudan.
Author’s contributions:- Study idea, design, practical, analysis, writing of manuscript and editing all by author 1 and the revising of paper by author 2.
Core tip: - A critical problem for hemodialysis patients is hepatitis infections. Some of the risk factors associated with HBV infection include blood transfusion, frequency, and duration of hemodialysis, and equipment contamination of infected patients. In fact, HCV infection through dialysis units has increased worldwide.
Abstract:
Objectives: The aim of this study was to determine the frequency of the hepatitis B virus (HBV) and hepatitis C virus (HCV) in hemodialysis patients in Portsudan city, Sudan during period July 2013.
Materials & methods: A total of ninety one hemodialysis patients, were enrolled in this study. Blood specimens were collected and examined by ELISA technique for the detection of hepatitis B surface antigen (HBsAg) and HCV antibodies (fourth generation).
Result: HBsAg was detected among 18(19.8%) patients, while 2(2.2%) patients had hepatitis C. Most of patients were males 66(72.5%), and their age ranged between 46 to 55with mean age of 50 years.
Conclusion: The frequency of HBV and HCV among the studied population is slightly high. Education for dangerous behaviors along with screening, vaccination, and appropriate treatment for hepatitis is strongly recommended to control this persistent infectious source of hepatitis B and C in the community.
Key Words: HBV; HCV; hemodialysis patients; ELISA technique.
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Article citation:-
Abbas. Israa, M. & El hag. Wafa. Frequency of hepatitis B and C among hemodialysis patients in Portsudan City, Sudan. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 September; 34(34): 1688-1692.
Copyright © 2013 Abbas. Israa, M. & El hag. Wafa. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
Original article
1SANNI, Momoh, *1EJEMBI, Daniel, 2EMMANUEL, T. Friday,
1ABBAH, Okpachi C. & 1OGALA, Emmanuel.
Affiliation:-
1Department of biochemistry, Kogi State University, Anyigba, Nigeria.
2Department of medical biochemistry, Kogi State University, Anyigba, Nigeria.
Author’s contributions- All authors contributed equally to this paper.
Abstract:
The effects of Chronic Administration of indomie instant noodles on the activity of alkaline phosphatase of rat small intestine were investigated. Forty eight (48) albino rats (Rattus novergicus) of average weight 210g were divided into 7 groups containing 6 rats except the 7th group which 12 rats as control; each group was further divided into equal number of males and females. Group 1 was fed with the noodle cooked and spiced, group 2 was fed with raw noodle spiced, and group 3 was fed with a mixture of the cooked and raw noodles and spiced with the seasoning. Groups 4-6 were fed in a repeated fashion as 1, 2 & 3 with the exclusion of the seasoning spice. Group 7 was fed with normal rat feed. Water was provided ad libitum. Animals were fed for thirty days and were sacrificed on the thirty first day after commencement of administration of test feed (indomie) and the organs of interest was collected and kept for analysis. The results obtained were statistically treated (p<0.05) at 95% confidence level using F-test with a positive association of consumption of indomie noodles with damage to small intestinal tissues was observed.
Key words: Indomie instant noodles; Alkaline phosphatase.
Article citation:-
Sanni et al. Effects of Chronic administration of indomie noodles on the activity of alkaline phosphatase of rat small intestine. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 September; 34(34): 1682-1687.Available at http://www.jpbms.info
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Copyright © 2013 Sanni et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
An Overview
*1Lau Himani, 2Lau Mayank, 3M U Swetha, 4Jasoria Gaurav, 5Babaji Prashant, 6Purohit Rajeev
Affiliation:-
1Reader, Department of Endodontics and Conservative Dentistry, Maharana Pratap Dental College & research centre, Putlighar Road, Gwalior HO, Gwalior – 474001, Madhya Pradesh, India.
2Department of Prasthodontics, MR Ambedkar Dental College & Hospital, Bangalore, India.
3Post-Graduate student, Department of Prosthodontics including Crown and Bridge and Implantology, MR Ambedkar Dental College and Hospital, Bangalore-560005, Karnataka, India
4Reader, Department of Orthodontics, Maharana Pratap Dental College & research centre, Putlighar Road, Gwalior HO, Gwalior – 474001, Madhya Pradesh, India.
5Associate Professor, Department of Pedodontics, Vyas Dental College, Jodhpur, India.
6Senior Resident, Department of Pedodontics & Preventive Dentistry, PBM Government Hospital, Bikaner, Rajasthan, India.
Abstract:
Lasers have revolutionized the field of dentistry. The development of many different types of laser during the past five decades has offered researchers many wavelengths of laser light to investigate for a variety of surgical and medical procedures. The physical development of lasers and the understanding of the various wavelengths, and as well as the improvement of the equipments have brought these two areas closer together, with laser representing an upgrade of dentistry as a whole, particularly in esthetics, conservative and prosthetics. This article illustrates the basics of laser science, tissue effects of dental lasers, various dental lasers wavelengths, laser parameters and safety measures to provide effective treatment to the patient.
Key words: Lasers, wavelength, dentistry.
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Review article
Amartya De1, Gayatri Dewangan2 & Akhilesh Mishra*3
Affiliation:-
1Department of Pharmacology, R.G. Kar Medical College & Hospital, Kolkata, WBUHS, Kolkata, India.
2Department of Pharmacology & Toxicology, COVSC, Mhow, India.
3Department of Pharmacology & Toxicology, WBUAFS, Kolkata, India.
Author’s contributions:- All the author contributed equally to this paper.
*Correspondence to:-
Dr. Akhilesh Mishra, PhD INSPIRE Fellow
Department of Pharmacology & Toxicology, WBUAFS, Kolkata, India.
Email: drakhileshvet@gmail.com
Abstract:
Epidermolysis Bullosa (EB) encompasses a number of disorders characterized by recurrent blister formation as the result of structural fragility within the skin and selected other tissues. Clinical manifestations ranges widely from localized blistering of the hands and feet to generalized blistering of the skin and oral cavity and injury to many internal organs. Epidermolysis Bullosa is a group of genetically determined disease characterized by abnormal damaged of the skin and mucosa. EB varies from mild to very sever and even lethal. The mild forms are all of autosomal dominant inheritance. Traditionally, EB is classified according to skin morphology to give three major categories. In this article we discuss mainly pathophysiology, diagnosis, surgical treatment, stem cell therapy, gene therapy and targeted protein therapy to manage the disease.
Key words: Epidermolysis Bullosa; skin blistering; autosomal dominant; pathophysiology.
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Article citation:-
Amartya De, Gayatri Dewangan & Akhilesh Mishra. Epidermolysis Bullosa and its Management. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 September; 34(34): 1637-1642.Available at http://www.jpbms.info
Copyright © 2013 Amartya De, Gayatri Dewangan & Akhilesh Mishra. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.