DocumentsDate added
Original article
Revathi S1,*, Anju Ade2,Chetana KV3,S G Hiremath4
Affiliation:-
1Assistant Professor,2Associate Professor, 3Post graduate,4Professor,Department of Community Medicine, Navodaya Medical College, Raichur, Karnataka, India
Author’s contributions:- All the authors contributed equally to this paper
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Community Medicine, Navodaya Medical College, Raichur, Karnataka, India
Corresponding author:-
Dr Anju Ade.
Associate professor,
Community Medicine Department, Navodaya Medical College, Raichur -584103, Karnataka, India
Abstract:
Background: Mother and child in a community constitute vulnerable group or special risk group, pregnancy and childbirth are special events in a women’s life. But during this period they are more vulnerable to disease and death. Lack of information and lack of economic resources are the main reasons for underutilization of services. Aims: To study the utilization pattern of post natal services.
To find out the factors influencing the utilization of post natal services. Material methods: This was cross sectional study conducted in an urban slum area (Harijanwada) of Raichur, Karnataka, India. A total of 380 mothers formed the study sample. Data was collected by house to house survey among mothers who delivered during June 2010 to May 2011 using predesigned and pretested questionnaire. Data was entered in a excel spreadsheet and analyzed by using SPSS software. The test applied was chi square test for proportions.
Results: Out of 380 mothers,207(54.5%) of the mothers delivered in government Hospital, 141(37.1%) in private Hospital and 32(8.4%) at home.297 (78.2%) mothers were delivered by Doctors, 51 (13.4%) by nurse 29 (7.6%) and 3 (0.8%) were delivered by unskilled birth attendant.168 (44.2%) had post natal check up and 212 (55.8) did not have post natal checkups, Reasons for not utilizing PNC ,106 (27.9%) of mothers were unaware was the main reason for not utilizing Postnatal care.
Key words: Utilization pattern; Post-natal care; Urban slum; Mothers.
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Article citation:-
Revathi S,Anju Ade,Chetana KV,S G Hiremath. A cross sectional study of utilization pattern of postnatal services in urban slums of Raichur city. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 November 36(36): 1909-1914. Available at www.jpbms.info.
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Source of support: Nil
Case report
Rokade Chakor.M1,Damle R.P2,Dravid N.V3,Saindane K A4,Mahale Y J5
Affiliation:-
1Assistant Lecturer, 2Assistant Professor, 3Professor and Head, Department of Pathology,4Associate Professor, 5Professor and Head, Department of Orthopaedics, JMF’s ACPM Medical College, Dhule, Maharastra, India
Corresponding author:-
Dr.Damle R.P.
Assistant Professor, Department of Pathology,
JMF’s ACPM Medical College, Dhule.
Contact no:-+91- 9767637624
Abstract:
Aneurysmal bone cyst (ABC) is a rare benign, vascular, solitary expansile erosive bone lesion. It expands from the affected bone and destroys the surrounding tissues. It account for less than 1% of primary bone tumour. It is related to the blow out distension with destruction of the affected bone and consists of blood filled spaces separated by fibrous tissue. ABC commonly affects the young adults under 20 years of age and occurs in metaphysis of long bone and vertebral body. Herein we report 4 cases of ABC at unusual sites arising from patella, second metatarsal, talus, and distal radius.
Key words: Aneurysmal bone cyst; metatarsal; patella; talus.
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Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Source of support: Nil
Article citation:-
Rokade Chakor.M,Damle R.P,Dravid N.V,Saindane K A,Mahale Y J. Aneurysmal bone cyst– Report of four cases at unusual sites. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 November 36(36): 1898-1901. Available at www.jpbms.info.
Copyright © 2013 Rokade Chakor.M,Damle R.P,Dravid N.V,Saindane K A,Mahale Y J. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article
Kamran Alam, Farya Zafar*, Huma Shareef
Affiliation:-
Ziauddin College of Pharmacy, Ziauddin University, 4/B, Shahrah-e-Ghalib, Block 6, Clifton, Karachi - 75600, Pakistan.
The name of the department and institution to which the work should be attributed:-
Ziauddin College of Pharmacy, Ziauddin University,4/B, Shahrah-e-Ghalib, Block 6, Clifton, Karachi - 75600, Pakistan
Author contributions:
KA: Study design, execution and analysis.
FZ: Writing and drafting the manuscript
HS: Literature search
*Correspondence to:-
Dr Farya Zafar
Associate Professor,
Ziauddin College of Pharmacy,
Ziauddin University,4/B, Shahrah-e-Ghalib, Block 6, Clifton, Karachi - 75600, Pakistan
Abstract:
Objectives: The aim of the present study was to develop Metformin Hydrochloride sustained release formulation and to estimate release parameters as per different kinetic models.
Material and Methods: Two hydrophilic formulations (FHL1 and FHL2) and two hydrophobic formulations (FHP1 and FHP2) were prepared. Formulations FHL1 and FHL2 were developed by varying the concentration of binders (independent variable) using Dextrose ranged from (0 – 30 %) and Plasdone S360 (19 – 49 %). Both formulations resulted in immediate release after being placed in dissolution medium at phosphate buffer pH 6.8. For such reason, both formulations were concluded to be ineffective. Also two hydrophobic formulations (FHP1 and FHP2) were developed, the independent variable selected was the tabletting technique i.e., wet granulation method was used to produce FHP1 using ethyl cellulose (25 %) and Di-Tab (24 %) and direct compression method was used to prepare FHP2 exhibiting ethyl cellulose (30 %) and Di-tab (19 %).
Results: Results of release profile indicated that FHP1 released 80 % of the drug up to 8 hr while FHP2 released 80 % drug up to 14 hrs. Formulation FHP1 was selected as a best formulation and was used to produce two more batches (B1 and B2). Powder blends of both the batches were evaluated for flow properties i.e., angle of repose, carr’s index and hausner’s ratio. Both the batches were assessed by various physico-chemical parameters and the results were found to be in acceptable limits. The marketed product Glucophage sustained release formulation was selected as a reference product. Dissolution profiles were also compared using phosphate buffer pH 6.8. Data were assessed by model dependent methods using different kinetic models which were zero-order, first order, higuchi model and korsmeyer peppas model in order to assess release kinetics.
Conclusion: Results indicated that First-order kinetics was fitted to all formulations. Also, similarity factor (f2) was determined. Results indicated that FHP1, batch 1 and batch 2 were found similar with the reference formulation at pH 6.8.
Key words: Metformin hydrochloride; Hydrophilic, hydrophobic; Wet granulation; Direct compression and dissolution profile.
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Article citation:-
Kamran Alam,Farya Zafar,Huma Shareef. Development and evaluation of metformin hydrochloride 500mg sustained release tablets. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 November; 36(36): 1844-1852. Available at http: //www.jpbms.info
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Source of support: Nil
Copyright © 2013 Kamran Alam,Farya Zafar,Huma Shareef. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article
Harish Kumar Jain*1,P. Jhanwar1,Suresh Dhakar2,Mukul Jain3,Manoj Sharma4
Affiliation:-
1Assosiate Professor, 2Senior Resident,3M.B.B.S. Student, 4Associate Professor, Jhalawar Medical College, Jhalawar (Rajasthan) India
The name of the department and institution to which the work should be attributed:-
Department of Orthopaedics, Jhalawar Medical College ,Jhalawar (Rajasthan) India
Author contributions:
First two author’s contributed equally to major work in this study like concept, literature search, design, clinical work, manuscript preparation. Last three author’s contributed in data acquisition and editing of manuscript.
Corresponding author:-
Dr. P. Jhanwar, M.S.(Ortho.)
Associate Professor, Jhalawar Medical College, Jhalawar (Rajasthan) India
Contact no:-+91-9414191125
Abstract:
Introduction: Supracondylar fracture of humerus is most common elbow injury in children, Blount et al. (1951)1. Complications including volkmann ischaemic contracture (VIC), myositis ossificans and permanent nerve lesions may cause serious functional loss, are fortunately uncommon, Henrikson B (1966)2.This prospective study was conducted from July 2010 to December 2011, to know the results of a new two stage reduction & plaster slab treatment of displaced supracondylar fractures of humerus in children.
Material & methods: Ninety patients of 2 to 10 years of age, with displaced supracondylar fractures of humerus, reported within 72 hours after fracture, were included in this study. New conservative management technique of two stage close reduction & plaster slab immobilization, named TSRT was used first stage on attending hospital first time and second after 5 days. Regular follow up till minimum of 6 months were done and at final follow up, clinical outcome was assessed, according to Flynn criteria.
Results: Eighty one(81) patients were followed up (out of 90 patients, 4 were of flexion type fracture and 5 lost during follow up). Sixty(60) (74%) were male and 21 (26%) were female child. According to Gartland classification 27 (33%) were type II and 54 (67%) were type III fractures. In 95 percent fractures, satisfactory results, and in 5 % cases poor results were achieved. VIC and myositis ossificans were found in none of the cases, where as cubitus varus in one patient and stiffness was found in one patient only.
Conclusion: New two stage close reduction and plaster slab technique (TSRT) produced excellent results. It is non invasive, cost effective, safe, less time consuming, less cumbersome technique, associated with full range of motion in all cases, even in those who are from rural background, with illiteracy & Ignorance.
Key words: Supracondylar fracture Humerus; two stage reduction technique [TSRT].
Article citation:-
Harish Kumar Jain,P. Jhanwar,Suresh Dhakar,Mukul Jain,Manoj Sharma. Displaced supracondylar fracture humerus in children : Excellent results with new two stage reduction technique. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 November 36(36): 1871-1875. Available at www.jpbms.info.
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Abbreviations:
VIC:Volkmann Ischaemic Contrature,TSRT:Two Stage Reduction Technique,AP:Anteroposterior,ROM:Range of Motion,AE:Above Elbow.
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Source of support: Nil.
Copyright © 2013 Harish Kumar Jain,P. Jhanwar,Suresh Dhakar,Mukul Jain,Manoj Sharma. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Silpiranjan Mishra1,*, C.Krithika2, RamachandranSudarshan3,S.C.Selvamuthukumar4, Priya Ramani2, S. Uma Maheswari1
Affiliation:-
1Post graduate trainee, 2Reader, 3Senior lecture, 4Professor and HOD, Department of Oral Medicine and Radiology, Thai Moogambigai dental college, Chennai, Tamilnadu, India
Author’s contributions- All the authors contributed equally to this paper
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Oral Medicine and Radiology, Thai Moogambigai dental college, Chennai, Tamilnadu India
Corresponding author:-
Dr. Silpiranjan Mishra.
Post graduate trainee,
Department of Oral Medicine and Radiology,
Thai Moogambigai dental college, Chennai, Tamilnadu, India
Ph no: 09176174611
Abstract:
The terms ‘‘Eagle’s syndrome’’ represents a series of symptoms caused by an elongated styloid process or the mineralization of part or the entire stylohyoid ligament. The symptoms of this syndrome can be varied and so the patients can present to general physicians, Otorhinolaryngologists or Dental surgeons for management. In many cases, it may just be an incidental finding with minimal or no symptoms. Diagnosis usually depends on clinical symptoms, digital palpation in the tonsillar fossa and infiltration with anesthetic agent, but diagnosis is ultimately confirmed by radiological findings. With the advancements in three dimensional imaging, dental surgeons are more likely to encounter this syndrome in their practice and hence they need to be familiar with the clinical presentation. The treatment can be conservative or surgical depending on the underlying pathogenesis and the extent to which anatomical structures are compressed or irritated by the styloid process. This review deals with the current understanding of the etiopathogenesis, clinical features, diagnosis and management of this clinically relevant condition.
Key words: Eagle’s syndrome; styloid; Dental surgeons.
Article citation:-
Silpiranjan Mishra, C.Krithika, Ramachandran Sudarshan, S.C.Selvamuthukumar,Priya Ramani,S. Uma Maheswari. Elongated styloid process- A review. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 November 36(36): 1871-1876. Available at www.jpbms.info.
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Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
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Copyright © 2013. Silpiranjan Mishra, C.Krithika, Ramachandran Sudarshan, S.C.Selvamuthukumar,Priya Ramani,S. Uma Maheswari. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.