DocumentsDate added
Research article
Pandav Amitkumar B.1,*,Nilkanth Somesh P. 2,Lanjewar Dhaneshwar N.3,
Bhagwat Rajendra V. 4
Affiliation:-
1Assistant Professor, Department of Pathology, Government MedicalCollege, Miraj. Maharashtra India
2Resident Pathology, Government Medical College, Miraj. Maharashtra India
3Professor, Department of pathology Government Medical College, Miraj. Maharashtra India
4Professor, Department of Medicine, Government Medical College, Miraj. And Incharge ART center P.V.P.Government Hospital, Sangli. Maharashtra, India
Author’s contributions- all the authors contributed equally to this paper
The name of the department(s) and institution(s) to which the work should be attributed:
Government Medical College & Hospital, Miraj, Sangli. Maharashtra, India
P.V.P.Government Hospital, Sangli. Maharashtra, India
Corresponding author:-
Dr. Pandav Amitkumar Bapuso
Assistant Professor, Department of Pathology, Government Medical College, Miraj, Maharashtra, India- 416410.Contact no: +91- 9881979069
Abstract:
Introduction: Haematologic manifestations are characteristic of the natural history of HIV infection. Clinically significant haematological abnormalities are common in persons with HIV infection. They have major morbidity in themselves, adversely altering patient's quality of life and hinder treatment of both the primary viral infection and the secondary infections and neoplastic complications.
Material and methods: This is a prospective cross sectional study of 713 HIV positive patients, conducted in the Department of Pathology of Government Medical College and Hospital Miraj and Padmabhushan Vasantdada patil General Hospital Sangli between the period August 2008 and July 2010. The hematological parameters were obtained by processing whole blood on Abacus Diatron Electronic Cell counter. Demographical and clinical data of the patient was also obtained. Data obtained from Electronic counter, peripheral smear examination and BD FACScan flow cytometer was put together and analyzed.
Results: Anaemia was the most common haematological abnormality observed. The overall prevalence of anaemia, neutropenia, thrombocytopenia, lymphopenia, leucopenia and pancytopenia was 44%, 2.3%, 6.7%, 7.4%, 5% and 1.1% respectively. The prevalence of all haematological abnormalities was higher in patients with advanced disease, CD4 count <200/ µl. ART was associated with lower prevalence of all haematological abnormalities. Eosinophilia was observed in 23% of patients and was associated directly with advanced stage of the disease, ART and CD4 count.
Conclusion: Prevalence of haematological abnormalities in HIV positive patients is significantly high even in this HAART era. ART is associated with reduced prevalence of all haematological abnormalities and has therapeutic and preventive implications.
Key words: Anaemia; ART; HAART; HIV; AIDS; Eosinophilia.
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Article citation:-
Pandav Amitkumar B.,Nilkanth Somesh P.,Lanjewar Dhaneshwar N.,Bhagwat Rajendra V.. Haematological profile of HIV-positive patients in relation to immune status and Stage of the disease - A hospital-based cohort from Western India. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 November 35(35): 1877-1886. Available at www.jpbms.info.
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Source of support: Nil
Copyright © 2013 Pandav Amitkumar B. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Majumdar Tapan1*, Bhattacharya Sibabrata2,Barman Debasis2, Baidya Subrata3
Affiliation:-
1 Associate Professor,2Assistant Professor, Department of Microbiology, 3Associate Professor, Department of Community Medicine, Agartala Goverment Medical College, P.O :-Kunjavan, Agartala, Tripura.-799006, India
The name of the Department and Institution to which the work should be attributed:-
Department of Microbiology,
Department of Community Medicine Agartala Goverment Medical College, P.O- Kunjavan, Agartala, Tripura.-799006, India
Author contributions:
All the authors equally to this paper
*Correspondence to:
Dr Tapan Majumdar.
Associate Professor, Department of Microbiology, Agartala Govt. Medical College, P.O- Kunjavan, Agartala, Tripura. PIN-799006, India.
Abstract:
Tripura experienced first outbreak of meningococcal infection in 2009. The outbreak started from the 3rd week of January 2009 and lasted till august 2009 with its peak in the month of may 2009.During this period number of confirmed cases was 285 with 62 deaths with an attack rate of 8.4/lakh and a case fatality rate (CFR) of 22%.As per the geographical clustering of cases, maximum were reported from Chawmanu block of Dhalai district where a total of 125 case were reported with 31 deaths and the CFR was reported to be 25% with an attack rate of 351/lakh. Strategy adopted for outbreak response was Chemotherapy, Chemoprophylaxis, Strengthening of laboratory diagnostics, Limited reactive use of Vaccine and Intensive IEC activity. The study was undertaken with the objective of follow up of trends in meningococcal infection in outbreak prone area in order to prevent further outbreak and also observe the impact of vaccination in the affected area. Though the laboratory investigation reports shows a declining trends but infection still continues to occur during the subsequent years with no reports of clustering of cases from any part of Tripura. 71 cases in 2010, 10 cases in 2011, 5 cases in 2012 and till April 2013 no cases were reported. Provision of easy access to effective treatment and reactive vaccination with a polysaccharide vaccine after an outbreak though resulted in reducing the infection rate but has not prevented the occurrence of infection and death (13 in 2010, 04 in 2011,03 in 2012). Molecular insight of the circulating clones, provision of conjugate vaccine and enhanced surveillance is the need of the hour for effective control of outbreak due to meningococcal infection.
Key words: Immunoprophylaxis; Chemoprohylaxis; Meningococcal infection; Outbreak; Surveillance.
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Article citation:-
Majumdar Tapan, Bhattacharya Sibabrata, Barman Debasis,Baidya Subrata. Impact of vaccination following outbreak of meningococcal infection in Tripura, India. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 November;36(36):1853-1859. Available at http: //www.jpbms.info.
Copyright © 2013 Majumdar Tapan. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Revathi S1,*, Anju Ade2,Chetana KV3,S G Hiremath4
Affiliation:-
1Assistant Professor,2Associate Professor, 3Post graduate,4Professor,Department of Community Medicine, Navodaya Medical College, Raichur, Karnataka, India
Author’s contributions:- All the authors contributed equally to this paper
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Community Medicine, Navodaya Medical College, Raichur, Karnataka, India
Corresponding author:-
Dr Anju Ade.
Associate professor,
Community Medicine Department, Navodaya Medical College, Raichur -584103, Karnataka, India
Abstract:
Background: Mother and child in a community constitute vulnerable group or special risk group, pregnancy and childbirth are special events in a women’s life. But during this period they are more vulnerable to disease and death. Lack of information and lack of economic resources are the main reasons for underutilization of services. Aims: To study the utilization pattern of post natal services.
To find out the factors influencing the utilization of post natal services. Material methods: This was cross sectional study conducted in an urban slum area (Harijanwada) of Raichur, Karnataka, India. A total of 380 mothers formed the study sample. Data was collected by house to house survey among mothers who delivered during June 2010 to May 2011 using predesigned and pretested questionnaire. Data was entered in a excel spreadsheet and analyzed by using SPSS software. The test applied was chi square test for proportions.
Results: Out of 380 mothers,207(54.5%) of the mothers delivered in government Hospital, 141(37.1%) in private Hospital and 32(8.4%) at home.297 (78.2%) mothers were delivered by Doctors, 51 (13.4%) by nurse 29 (7.6%) and 3 (0.8%) were delivered by unskilled birth attendant.168 (44.2%) had post natal check up and 212 (55.8) did not have post natal checkups, Reasons for not utilizing PNC ,106 (27.9%) of mothers were unaware was the main reason for not utilizing Postnatal care.
Key words: Utilization pattern; Post-natal care; Urban slum; Mothers.
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Article citation:-
Revathi S,Anju Ade,Chetana KV,S G Hiremath. A cross sectional study of utilization pattern of postnatal services in urban slums of Raichur city. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 November 36(36): 1909-1914. Available at www.jpbms.info.
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Source of support: Nil
Case report
Rokade Chakor.M1,Damle R.P2,Dravid N.V3,Saindane K A4,Mahale Y J5
Affiliation:-
1Assistant Lecturer, 2Assistant Professor, 3Professor and Head, Department of Pathology,4Associate Professor, 5Professor and Head, Department of Orthopaedics, JMF’s ACPM Medical College, Dhule, Maharastra, India
Corresponding author:-
Dr.Damle R.P.
Assistant Professor, Department of Pathology,
JMF’s ACPM Medical College, Dhule.
Contact no:-+91- 9767637624
Abstract:
Aneurysmal bone cyst (ABC) is a rare benign, vascular, solitary expansile erosive bone lesion. It expands from the affected bone and destroys the surrounding tissues. It account for less than 1% of primary bone tumour. It is related to the blow out distension with destruction of the affected bone and consists of blood filled spaces separated by fibrous tissue. ABC commonly affects the young adults under 20 years of age and occurs in metaphysis of long bone and vertebral body. Herein we report 4 cases of ABC at unusual sites arising from patella, second metatarsal, talus, and distal radius.
Key words: Aneurysmal bone cyst; metatarsal; patella; talus.
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8.Lichtenstein L. Aneurysmal bone cyst; further observations. Cancer.1971; 28(3) : 597-604.
9.Panoutsakopoulos G, Pandis N, Kyriazoglou I, Gustafson P, Mertens F,Mandahl N. Recurrent t(16;17)(q22;p13) in aneurysmal bone cysts. Genes Chromosomes Cancer. 1999; 26(3):265-266
10.Oliveira AM, Hsi BL, Weremowicz S, et al. USP6 (Tre2) fusion oncogenes in aneurismal bone cyst. Cancer Res. 2004; 64(6):1920-1923.11
11.Leithner A, Lang S, Windhager R, et al. Expression of insulin-like growth factor-I (IGFI) in aneurysmal bone cyst. Mod Pathol.2001; 14(11):1100-1104.
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Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Source of support: Nil
Article citation:-
Rokade Chakor.M,Damle R.P,Dravid N.V,Saindane K A,Mahale Y J. Aneurysmal bone cyst– Report of four cases at unusual sites. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 November 36(36): 1898-1901. Available at www.jpbms.info.
Copyright © 2013 Rokade Chakor.M,Damle R.P,Dravid N.V,Saindane K A,Mahale Y J. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article
Shankar M Bakkannavar, MD DCL 1,*, Pratik V Taravadi, MD 2,Pavanchand Shetty,MD3,Raghavendra Babu YP, MD4, Vinod C Nayak, MD1, Pradeep Kumar G, MD, Dip. Cr.L5,
Affiliation:-
1Associate Professor, Department of Forensic Medicine and Toxicology, Kasturba Medical College, Manipal, Manipal University, India.
2Assistant Professor, Department of Forensic Medicine and Toxicology, K.S. Hegde Medical Academy, Nitte University, Mangalore, India
3Assistant Professor, Department of Forensic Medicine and Toxicology, Kasturba Medical College, Manipal,Manipal University, India.
4Associate Professor, Department of Forensic Medicine and Toxicology, Kasturba Medical College, Mangalore, Manipal University, India.
5Professor, Department of Forensic Medicine and Toxicology, Kasturba Medical College, Manipal,Manipal University, India.
Author’s contributions- all the authors contributed equally to this paper
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Forensic Medicine & Toxicology
Kasturba Medical College, Manipal University, Manipal-576104, India.
Corresponding author:-
Dr Shankar MBakkannavar
Associate Professor
Department of Forensic Medicine & Toxicology
Kasturba Medical College, Manipal-576104, India.
Phone No.+91-820-2922450 (O) +91-9845303881 (M)
Abstract:
Teeth play an important role in the field of forensic investigations. Their ability to survive in mass disasters makes them an important tool in identification of the victim. Though the morphology and structure is similar in both males and females, there are subtle differences. Variation in dental size can give a clue about differences between the sexes.Many authors have measured the width of teeth in both males and females and found certain variations. Canines, reported to survive in air crash and hurricane disasters, are perhaps the most stable teeth in the oral cavity because of the labiolingual thickness of crown and the root anchorage in the alveolar process of the jaws. Not only the Mesio-distal width of canines but also the intercanine distances help in identifying the gender as a part of identification. Measurement of inter-caninedistances of the mandible and maxilla provides good evidence of sex identification due to dimorphism.
Key words: Identification; Inter-canine distance; Mandibular; Sexual Dimorphism.
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Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
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Article citation:-
Shankar M Bakkannavar, Pratik V Taravadi,Pavanchand Shetty, Raghavendra Babu YP, Vinod C Nayak,Pradeep Kumar G. Gender Differentiation using Inter-Canine Distances among South Indians. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 November 35(35): 1860-1865. Available at www.jpbms.info.
Copyright © 2013 Shankar M Bakkannavar. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.