DocumentsDate added
Original article
Panjiyar K.Shambhu1,*,Kumari A.R2,Jayaram Subha3,Pandey Rajesh4,Singh Jasbir4
Affiliation:-
1Lecturer, Department of Biochemistry, Kantipur Dental College, Kathmandu, Nepal
2Professor, 3Assistant Professor, Department of Biochemistry, PES Medical College, Kuppam, Andhra Pradesh, India
4Professor, Department of Biochemistry, MMIMSR, Mullana, Ambala, Haryana, India
The name of the department(s) and institution(s) to which the work should be attributed:
1. Department of Biochemistry, Kantipur Dental College, Kathmandu, Nepal.
2. Department of Biochemistry, PES Medical College, Kuppam, Andhra Pradesh,India
3. Department of Biochemistry, MMIMSR, Mullana, Ambala, Haryana,India
*Corresponding author:-
Shambhu K. Panjiyar.
Lecturer, Department of Biochemistry, Kantipur Dental College, Kathmandu, Nepal
Mobile: 00977-9841155094
Abstract:
Context: Chronic kidney disease (CKD) is an increasing health problem worldwide. The status of trace elements in CKD, though altered, is often unexplored.
Aim: To evaluate serum zinc, copper and magnesium in CKD patients, before and after hemodialysis (HD).
Setting and design: Community-based prospective cross-sectional study in rural setting of Andhra Pradesh.
Materials and methods: 30 cases diagnosed as CKD patients undergoing HD, and 30 healthy subjects as controls were selected. The cases were further divided into 2 groups namely pre-HD and post-HD. In each subject, serum zinc, copper and magnesium were analyzed.
Statistical analysis: It was done by entering the data in SPSS version 12 [SPSS v12 (SPSS Inc, Chicago, IL)]. Bar charts and tables were prepared in Microsoft excel 2007 software program.
Results: Serum zinc levels are decreased in CKD, however, the pre-HD and post-HD values were not significantly different. Serum copper levels were unaltered. Finally, serum magnesium levels were increased in CKD but decreased significantly following HD.
Conclusions: Alteration in trace elements may occur in CKD, and may be further modified by HD. This aspect requires attention and rectification where necessary.
Keywords: Chronic kidney disease; copper; hemodialysis; magnesium; trace elements; zinc.
Panjiyar K.Shambhu,Kumari A.R,Jayaram Subha,Pandey Rajesh,Singh Jasbir. Evaluation of serum zinc, copper and magnesium in patients with chronic kidney disease, before and after hemodialysis. J Pharm Biomed Sci 2014; 04(02): 88-91. Available at www.jpbms.info.
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Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Source of support: None
Copyright © 2014 Panjiyar K.Shambhu,Kumari A.R,Jayaram Subha,Pandey Rajesh,Singh Jasbir. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Review article
Gandhi M. 1,* & Swaminathan S2
Affiliation:-
1Lab Technologist, Department of Biochemistry, Central Lab, 2Chief of Biochemistry , Department of Biochemistry, Central Lab, SRM Medical College Hospital and Research Centre, Kattankulathur. Kancheepuram District 603 203, South India.
The name of the department(s) and institution(s) to which the work should be attributed:
Central Lab, SRM Medical College Hospital and Research Centre, Kattankulathur. Kancheepuram District 603 203, South India.
Authors contribution: Both the author contributed equally to this paper.
*Corresponding author:-
Dr.Swaminathan S
Central Lab, SRM Medical College Hospital and Research Centre, Kattankulathur. Kancheepuram District 603 203, South India.
Abstract: It has been universally established that many factors are involved in inducing obesity which in turn is linked to Diabetes and that people who are obese have a tendency to acquire type 2 Diabetes mellitus. Studies conducted worldwide reveals that obesity may be due to several uncontrolled factors such as fatty liver, Adipose tissue fat content , eating Jung food, smoking, alcohol use, hypertension and sedentary life style. This paper gives an up to date review of many factors involved in the development of obesity which in turn induce type 2 Diabetes. It also highlights some special tests that may help to diagnose and to work out on strategies to treat such syndromes.
Keywords: Chronic kidney disease; copper; hemodialysis; magnesium; trace elements; zinc; Obesity, DM; T2DM; FFA;MH; ANP.
Gandhi M. & Swaminathan S. An update on the factors leading to obseity and their association to diabetes mellitus. J Pharm Biomed Sci 2014; 04(02): 72-79. Available at www.jpbms.info.
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Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Panjiyar K.Shambhu,Kumari A.R,Jayaram Subha,Pandey Rajesh,Singh Jasbir. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.