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Research article
Khetri R1, Dugar D2,*, Ghata S3
Affiliation:-
1Associate professor, 2Assistant professor, 3 2nd year P.G Student, Department of General surgery, Hi-Tech Medical College and Hospital, Bhubaneswar, Odisha, India.
The name of the department(s) and institution(s) to which the work should be attributed:
Department of General surgery, Hi-Tech Medical College and Hospital, Bhubaneswar, Odisha, India
*To whom it corresponds:-
Dr. DHARMENDRA DUGAR M.S.
Department of General surgery, Hi-Tech Medical College and Hospital, Bhubaneswar, Odisha, India
Contact no:- +91-9437091846+91-9437091846
Abstract
Background: Inguinal hernia repair is one of the most commonly performed general surgical procedures in practice. The introduction of a laparoscopic technique has sparked a debate in the literature over the superiority of this method versus open repair. In this article, we examine the advantages and disadvantages of these two approaches in inguinal hernia repair.
Material & method: We conducted a prospective interventional type of hospital based study of 40 patients with inguinal hernia. Out of this 20 patients underwent laparoscopic repair (TEP) and the rest had open hernia repair. Patients were selected considering the inclusion and exclusion criteria. Factors studied were operative time, post-op pain and complications comparing both procedures. Follow-up was done for 2 years.
Result: Laparoscopic hernia repair compared to open method takes more operative time [79min/61min], less painful [1.5/3 in visual analogue], less hospital stay [3days/8days] respectively. There was no major complication in both the procedure and no recurrence in 2 years of follow-up.
Conclusion: Laparoscopic hernia repair is superior to open hernia repair in respect to post-operative pain, ambulation and easy return to work in experienced hands. Laparoscopy is safe with complication rate same as open hernia repair performed by a surgeon experienced in laparoscopic technique.
Key words: Laparoscopy, Totally-Extraperitoneal, Transabdominal-Preperitonealdfgj.
REFERENCES
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8.Stoker DL, Spegelhalter DJ, Singh R, et al. Laparoscopic versus open inguinal hernia repair, randomiz.d prospective trial. Lancet 1994; 343 : 1243-1245.
9.Felix E, Crafton B, Scott S, Geis P, Duncan T, Sewell R, et al. Causes of recurrence after laparoscopic hernioplasty. A multicenter study. SurgEndosc 1998; 12: 226- 31.
10.Ferzli GS, Frezza EE, Pecoraro AM Jr, Ahren KD. Prospective randomized study of stapled versus unstapled mesh in a laparoscopic pre peritoneal inguinal hernia repair. J Am CollSurg 1999; 188 : 461-5
11.MRC, Cost-utility analysis of open versus laparoscopic groin hernia repair: results from a multicenter randomized clinical trial. Br J Surg, 2001; 88(5):653-61.
Article citation:
Khetri R, Dugar D, Ghata S. Comparative Study of Open Versus Laparoscopic Inguinal Hernia Repair. J Pharm Biomed Sci. 2014; 04(02): 113-117. Available at www.jpbms.info
Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Abbreviations: Laparoscopy: Lap; Totally-Extraperitoneal: TEP; Transabdominal-Preperitoneal:TAPP.
Copyright © 2014 Khetri R, Dugar D, Ghata S. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Case report
Srivastava Monika1,*,Abhijeet Yadav1,Baweja Sonia2,Sharma Vandana3,Dixit Asha4
Affiliation:-
1M.B.B.S,Post Graduate Student, Department of Anatomy, Gandhi Medical College, Bhopal (MP),India
2MS,Assistant Professor,3MS, Associate Professor,4MS, Professor & Head, Department of Anatomy, Gandhi Medical College, Bhopal (MP),India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Anatomy,
Gandhi Medical College, Bhopal (MP), India
*Corresponding author:-
Dr. Monika Srivastava.
C/o Mr. R.K Srivastava
H.No 1532, Near Ebnezer School,
Bhagat Singh Nagar, Bhind Road
Gola Ka Mandir, Gwalior (MP)-474005,India
Contact No: 09893553306, 09027156756
Abstract:
Background: Sternalis is a mysterious strap like muscle present in approx. 3-4% of population. Its awareness among surgeons & radiologist is imperative as it may lead to misdiagnosis and have huge clinical implications.
Aim: To study anatomical & morphological characteristics of the study muscle.
Material & Methods:- A formalin preserved male cadaver was incised in the mid sternal line. Bilateral strap muscles were seen in the parasternal region. The area was cleaned and properly visualized. Subsequently, it was measured and photographed with proper labels.
Result: Muscles were present on the anterior wall of the thorax. Both had an aponeurotic origin. The tendon of the left side was intermingled with Sternoclediomastiod while the right one was intermingled with the muscles fibers of the Pectoralis Major of both the side. Neurovascular supplies of both the side were from the intercostals nerves and vessels.
Conclusion: Dissected muscles were Sternalis Muscles. They were straight muscles that were present in the parasternal area with separate origins and insertions with no boney attachment as a Panniculous Carnosus muscle
Keywords: Sternalis; Panniculous Carnosus; Bilateral Strap Muscles.
Srivastava Monika,Abhijeet Yadav,Baweja Sonia,Sharma Vandana,Dixit Asha. A Case report on bilateral rectus sternalis muscles: A mysterious muscles. J Pharm Biomed Sci 2014; 04(02): 80-83. Available at www.jpbms.info.
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Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Source of support: None
Copyright © 2014 Srivastava Monika,Abhijeet Yadav,Baweja Sonia,Sharma Vandana,Dixit Asha. This is an open access article distributed under the Creative Commons Attribution. a
Original Article
Thalquotra Mohit 1,*, Pandey Rajesh2, Singh Jasbir2, Agrawal B.K.3, Sodhi K.S.2
Affiliation:-
1P.G. student, Department of Biochemistry, MMIMSR, Mullana, Ambala, Haryana, India
2Professor, Department of Biochemistry, MMIMSR, Mullana, Ambala, Haryana, India
3Professor, Department of Medicine, MMIMSR, Mullana, Ambala, Haryana, India
The name of the department(s) and institution(s) to which the work should be attributed:
1. Department of Biochemistry, MMIMSR, Mullana, Ambala, Haryana, India
2. Department of Medicine, MMIMSR, Mullana, Ambala, Haryana, India
*To whom it corresponds:-
Mohit Thalquotra.
P.G. student, Department of Biochemistry, MMIMSR, Mullana, Ambala, Haryana,India
Mobile:+91-8221033642+91-8221033642
Abstract
Context: Chronic kidney disease (CKD) is a worldwide health problem with an increasing incidence and prevalence. Abnormalities in the structure and function of the thyroid gland and in the metabolism and plasma concentration of thyroid hormones are common in patients with CKD.
Aims: In view of variability of thyroid function tests reported in patients with CKD in previous studies, a prospective study of thyroid profile was performed in patients with CKD.
Setting and design: Prospective cross sectional study in rural setting of Haryana.
Materials and Methods: Total number of 30 patients with CKD on conservative management who were admitted to Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala during the period January 2013-January 2014 were selected in this prospective study. There were two groups (30 patients and 30 controls). Serum T3, T4 and TSH were evaluated in the subjects of both the groups and compared.
Statistical analysis: By SPSS version 12 [SPSS v12 (SPSS Inc., Chicago, IL)].
Results: 23.33% of the uremic patients kept on conservative treatment or on regular hemodialysis showed significant reduction of serum T3 and T4 in comparison to the control group. However, the level of TSH did not show significant alterations.
Conclusions: Thyroid dysfunction merits attention for the better management of CKD patients.
Keywords: Chronic kidney disease, Hemodialysis, Triiodothyronine (T3), Thyroxine (T4), Thyroid stimulating hormone (TSH).
REFERENCES
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5.Kaptein EM,Quion-Verde H, Chooljian CJ, Tang WW, Friedman PE, Rodriquez HJ, et al. The thyroid in end stage kidney disease. Medicine (Baltimore) 1988; 67: 187-97.
6.Bargman JM,SKorecki K. Chronic kidney disease. In: Longo DL, Fauci AS, Kasper DL. Harrison’s Principles of Internal Medicine, Vol. 2, 18th edn., 2011; McGraw Hill, London, pp. 2289-2313.
7.Weissel M,Stummvoll HK, Kolbe H, Höfer R. Basal and TRH stimulated thyroid and pituitary hormones in various degree of kidney insufficiency. Acta Endocrinol 1979; 90: 23-32.
8.Jain R, Isaac RM, Gottschalk ME. Transient central hypothyroidism as a cause of failure to thrive in newborns and infants. J Endocrinol Invest 1994; 17:631-637.
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11.Kaptein EM.Thyroid hormone metabolism and thyroid diseases in chronic kidney failure. Endocr Rev 1996; 17: 45–63.
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14.Zoccali C, Tripepi G, Cutrupi S, Pizzini P, Mallamaci F. Low triiodothyronine: A new facet of inflammation in end-stage kidney disease. J Am Soc Nephrol 2005;16: 2789–2795.
15.Carrero JJ, Qureshi AR, Axelsson J, Yilmaz MI, Rehnmark S, Witt MR et al. Clinical and biochemical implications of low thyroid hormone levels (total and free forms) in euthyroid patients with chronic kidney disease. J Intern Med 2007; 262: 690–701.
16.Wiederkehr MR, Kalogiros J, Krapf R. Correction of metabolic acidosis improves thyroid and growth hormone axes in haemodialysis patients. Nephrol Dial Transplant 2004; 19: 1190-1197.
17.Yilmaz MI, Sonmez A, Karaman M, Ay SA, Saglam M, Yaman H, et al. Low triiodothyronine alters flow-mediated vasodilatation in advanced nondiabetic kidney disease. Am J Nephrol 2011; 33: 25-32.
18.Zoccali C, Benedetto F, Mallamaci F, Tripepi G, Cutrupi S, Pizzini P, et al. Low triiodothyronine and cardiomyopathy in patients with end-stage kidney disease. J Hypertens 2006; 24: 2039-2046.
19.Zoccali C, Mallamaci F, Tripepi G, Cutrupi S, Pizzini P. Low triiodothyronine and survival in end-stage kidney disease. Kidney Int 2006; 70: 523–528.
20.Song SH,Kwak S, Lee DW, Kang YH, Seong EY, Park JS et al . The prevalence of low triiodothyronine according to the stage of chronic kidney disease in subjects with a normal thyroid-stimulating hormone. Nephrol Dial Transplant 2009; 24:1534–1538.
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Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Article citation:
Thalquotra Mohit ,Pandey Rajesh, Singh Jasbir, Agrawal B. K., Sodhi K.S. Evaluation of thyroid profile in patients with chronic kidney disease. J Pharm Biomed Sci 2014; 04(02): 143-147. Available at www.jpbms.info.
Copyright © 2014 Thalquotra Mohit, Pandey Rajesh, Singh Jasbir, Agrawal B. K., Sodhi K.S. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Olayode Olusina S1(MSc), Azubuike Chukwuemeka P1,* (PhD), Igwilo Cecilia I1 (PhD)
Affiliation:-
1Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Lagos, P.M.B.12003, Lagos, Nigeria
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Lagos, P.M.B.12003, Lagos, Nigeria
*Corresponding author:-
Azubuike Chukwuemeka P.
Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Lagos, P.M.B.12003, Lagos, Nigeria
Email: cazubuike@unilag.edu.ng Phone no: +234-8033618556+234-8033618556
Abstract:
The security and purity of low density polyethylene packaged water for human consumption during their shelf life was studied.
Assessment of protective ability of thin film polyethylene packaging material of twelve brands of sachet water randomly obtained in Mushin area of Lagos state was carried out by challenging the samples with Escherichia coli, methyl violet solution and dual purpose kerosene (DPK) respectively to estimate the extent it protects the content (water) from being contaminated by microorganisms, solute and vapour.
Five of the twelve brands (41.7%) were contaminated with microorganisms most likely during production. A brand was contaminated with Escherichia coli while another one with Schistosoma spp. Three other brands were contaminated with Shigella spp. Microbiological challenge test result indicated presence of challenge organism in one brand within two weeks and in three brands at fourth week. At third day of exposure to DPK, eight brands had smell and tastes of DPK, all the brands were permeated by DPK at seventh day of exposure. Only one brand was penetrated by dye (methyl violet) at first week of immersion and five other brands at fourth week of immersion.
The study shows the need for the improvement of the quality of the packaging materials for sachet water and the also the need to reduce its shelf life.
Keywords: Challenge test, Escherichia coli, Low Density Polyethylene and packaged water.
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Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Source of support: None.
Article citation:
Olayode Olusina S,Azubuike Chukwuemeka P,Igwilo Cecilia I.Assessment of the effects of low density polyethylene packaging materials on the content of sachet water marketed in Mushin Local Government Area, Lagos, Nigeria. J Pharm Biomed Sci. 2014; 04(02):100-105. Available at www.jpbms.info.
Copyright © 2014Olayode Olusina S,Azubuike Chukwuemeka P,Igwilo Cecilia I.This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article:
Ezissi Anthony I*, Ezejindu Damian N ,Ejimofor Obioma C
Affiliation:-
Department of Anatomy, College of Health sciences, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria.
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Anatomy, College of Health sciences, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria.
*Corresponding author:-
Ezissi Anthony I.
Department of Anatomy, College of Health sciences, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria
Phone no: - +2348065931492+2348065931492
Abstract:
The present study is aimed at studying the histological changes that might occur at the liver as a result of consumption of yaji – a Nigerian meat sauce with complex mixtures of spices and additives. The study was prompted by the reports of cytotoxicity and excitotoxicity of some of its spices and additive constituents. Twenty wistar rats of an average weight of 215g were used for the study and were divided into 4 groups of 5 rats in each group. Group A served as the control and received 71g of normal feed (growers mash), while the experimental groups B, C, D received 71g of normal feed with 5g, 10g and 15g of yaji respectively. The animals were sacrificed after 60 days (2 months) of administration of yaji. The results showed that the consumption of yaji in small amount had no effects on the histological appearance of the liver. But a large/excessive consumption of yaji induced mild distortions of histological liver appearance which includes mild central vein hypertrophy, increased cellularity and increase in vascularity with signs of edema.
Keywords: Yaji; Body weight; Liver weight; Suya.
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Article citation:
Ezissi Anthony I,Ezejindu Damian N.,Ejimofor Obioma C. A Study on the Histological Effects of Consumption of Yaji on the Liver of Wistar Rats. J Pharm Biomed Sci 2014; 04(02): 106-112. Available at www.jpbms.info.
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Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Ezissi Anthony I,Ezejindu Damian N.,Ejimofor Obioma C. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.