DocumentsDate added
Original article:
Archith Boloor MD1, Amina Asfiya M Iqbal2, Jagadish Rao Padubidri MD, DNB3,*
Affiliation:-
1Assistant Professor, Department of Medicine, Kasturba Medical College, Mangalore, Karnataka, India
[Affiliated to Manipal University].
2Under-Graduate Trainee, Department of Medicine, Kasturba Medical College, Mangalore, Karnataka, India
[Affiliated to Manipal University].
3Associate Professor, Department of Forensic Medicine, Kasturba Medical College, Mangalore, Karnataka, India
[Affiliated to Manipal University].
The name of the department(s) and institution(s) to which the work should be attributed:
Kasturba Medical College, Mangalore, Karnataka, India [Affiliated to Manipal University].
Abstract
In underdeveloped nations it is a known fact that may subjects have been most prone to the considerable and often destructible presence of malnutrition and tuberculosis. The nutritional status of patients suffering from tuberculosis assumes significant importance both in its prevention and progress. The present preliminary study was carried out to in the city of Mangalore and Moodshedde, Dakshina Kannada, Karnataka, India to unexplore the relationship between tuberculosis and malnutrition. We included 100 subjects suffering from pulmonary tuberculosis out of which 80 were males and 20 females with an average age of 42.3 years. The objective of our study was to analyze the coexistence of malnutrition and pulmonary tuberculosis. This investigation targeted at exploring the role of malnutrition as a critical predisposing factor in the development of pulmonary tuberculosis and also its consequences. The data collected included Body Mass Index (BMI), weight, height, mid upper arm circumference, haemoglobin and albumin levels. The dietary habits, including tobacco intake and alcohol consumption were enquired about with the help of recall method. Detailed physical examination was carried out to determine protein energy malnutrition and any deficiency of vitamins and/or minerals. We found that majority of the subjects (79%) were underweight having a BMI< 18 kg/m2, The subjects were not consuming enough calories in their diet and had daily intake of calories less than 1800 C. The vitamins and minerals that the subjects were lacking mainly included vitamin C, vitamin A, vitamin B- complex and folic acid.
Hence in our preliminary study we established a significant association between malnutrition and pulmonary tuberculosis. However the study needs to be carried out with more number of patients in order to obtain conclusive evidence.
Keywords: Malnutrition, Tuberculosis, BMI, protein malnutrition, Vitamin deficiency..
*To whom it corresponds:-
Dr. Jagadish Rao Padubidri,
Associate Professor, Forensic Medicine and Toxicology, Kasturba Medical College, Light House Hill Road, Mangalore-1, Karnataka, India.[ Affiliated to Manipal University]
Email: ppjrao@gmail.com. Contact No: +91-9900405085.
ACKNOWLEDGEMENTS
The authors would like to acknowledge the timely support of Indian Council of Medical Research (ICMR) in conduction of this study under STS-ICMR Project 2009.
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Article citation:
Boloor A., Amina A. M.I., Padubidri JR. Malnutrition: the underestimated link in the pathogenesis of pulmonary tuberculosis- A preliminary study. J Pharm Biomed Sci 2014;04(05):473-481. Available at www.jpbms.info.
Competing interest /Conflict of interest:
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Boloor A., Amina A. M.I., Padubidri JR. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article
Pushpa Thakur1,* & M.S.Thakur2
Affiliation:-
1Research Officer, IIHS, Himachal Pradesh University Shimla-171005, India
2Scientist, Department of Biosciences, Himachal Pradesh University Shimla-171005, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Biosciences, Himachal Pradesh University Shimla-171005, India
Author’s contribution: Both the author contributed equally to this paper.
*To whom it corresponds:-
M. S. Thakur,
Scientist, Department of Biosciences,
Himachal Pradesh University Shimla- 171005, India.
Phone: +91 177 2830946(O), 2812514®.
Email: mahender74@yahoo.co.in
Abstract:
In the current investigation the impact of vitamin-E treatment in the liver of white leghorn Chick subjected to 5.6 Gy whole body gamma radiations were studied. The study was conducted on 7 days old male chick for a maximum period of 35 days. Changes in mortality rate, body weight and liver weight along with radiation induced changes in histological profile of the chick liver, have been considered for the study. Vitamin–E treatment has been reported to be beneficial in amelioration of radiation induced changes in body weight, liver weight and hepatic architecture. Survival was significantly increased in chicks given vitamin–E treatment as compared to chicks given radiation alone (without vitamin–E Treatment).
Keywords: Vitamin–E; gamma radiation; chick; liver.
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Article citation:
Thakur P, Thakur MS. Impact of vitamin-E treatment in radiation (Y-irradiation) induced changes in chick liver. J Pharm Biomed Sci 2014;04(05):467-472.Available at www.jpbms.info.
Research article
AL Saleh, Essa M (DrPh)1,2 *, Ahmed Ibrahim (PhD)2 and Mwanri, Lillian (FAFPHM)1
Affiliation:-
1Discipline of Public Health, Flinders University, South Australia
2King Fahad Hofuf Hospital, Saudi Arabia
The name of the department(s) and institution(s) to which the work should be attributed:
Discipline of Public Health, School of Health Sciences, Faculty of Medicine, Nursing and Health Sciences, Flinders University
King Fahad Hofuf Hospital, Infection Control Department, Saudi Arabia
*To whom it corresponds:-
Dr. AL Saleh,Essa;
Infection Control Department, King Fahad Hofuf Hospital, Saudi Arabia. Post Box: 40461 AlAhsa 31982, Saudi Arabia
Tel: 0096650492681200966504926812
Abstract
Introduction: Healthcare workers (HCWs)’ education, awareness and adherence to clinical guidelines have been identified as necessary elements to prevent healthcare associated infections (HAIs) and multidrug resistant organisms (MDROs). The purpose of this study was to examine HCWs knowledge, attitudes and practices (KAP) towards HAIs management.
Methods: A cross sectional survey was conducted among HCWs including doctors and nurses in ICU of King Fahad Hofuf Hospital (KFHH), Saudi Arabia.
Results: 78.9% of participants responded to the survey and 63.4% of respondents had worked in the hospital for two to five years. There were differences in KAP in HAIs control between doctors and nurses. 56% of doctors compared to 83.6% of nurses responded appropriately regarding the necessity to inform all patients about HAIs especially MDROs (x2 = 7.32,p=0.07) . 92% of doctors compared to 68.9% of nurses reported that patients’ history influenced their decisions in choosing personal protective equipment (PPE) (x2 = 5.15,p=0.023). 68% of doctors compared to 88.5% of nurses reported that they always washed their hands before handling patients (x2= 6.32,p=0.042). 88% of doctors compared to all nurses reported that they always wore protective measures when handling patients with Acinetobacter infection (x2 = 7.59,p=0.023).
Conclusions: Although participants’ knowledge on various aspects of HAIs was generally high, it did not correspond to practices. Lack of strict adherence to HAIs management strategies could introduce and transmit HAIs and MDROs and may jeopardise patients’ life.
Keywords: Infection control; healthcare workers; knowledge; attitude; practices; Saudi Arabia.
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Article citation:
AL Saleh, Essa M, Ahmed Ibrahim and Mwanri, Lillian. Healthcare Workers’ Knowledge, Attitudes and Practices in King Fahad Hofuf Hospital, Saudi Arabia. J Pharm Biomed Sci 2014;04(05):410-421. Available at www.jpbms.info.
Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 AL Saleh, Essa M, Ahmed Ibrahim and Mwanri, Lillian. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Case report
Girish Gopal1,*, Gangadhar.B. Belavadi2
Affiliation:-
1Senior Resident, Department of Pediatrics, Mysore Medical College and Research Institute, Mysore -570001, Karnataka, India
2Professor and Head, Department of Pediatrics, Bangalore Medical College and Research Institute, Bangalore - 560002, Karnataka.
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Pediatrics, Mysore Medical College and Research Institute, Mysore -570001, Karnataka,India
Department of Pediatrics, Bangalore Medical College and Research Institute, Bangalore - 560002, Karnataka,India
Abstract
Ichthyosis constitutes a heterogenous family of skin disorders with Harlequin ichthyosis being the most severe genetic form. It is an autosomal recessive disorder characterized by dry, severely thickened skin with large plaques of hyperkeratotic scales, separated by moist and deep erythematous fissures. Altered development of the skin in utero due to defective lipid metabolism in the lamellar granules of the keratinocytes results in this condition and is usually fatal in the neonatal period. We report a neonate with this rare form of congenital ichthyosis.
Keywords: Autosomal recessive, erythematous fissures, Harlequin ichthyosis, hyperkeratotic scales.
*To whom it corresponds:-
Dr. Girish Gopal;
Senior Resident,
Department of Pediatrics, Mysore Medical College & Research Institute, Irwin Road, Mysore – 570001, India
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Article citation:
Girish G,Belavadi GB. Harlequin Ichthyosis – A case report. J Pharm Biomed Sci 2014;04(05):439-442. Available at www.jpbms.info.
Copyright © 2014 Gopal Girish,Belavadu GB. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Case report
Girish Gopal1,*, Gangadhar.B. Belavadi2
Affiliation:-
1Senior Resident, Department of Pediatrics, Mysore Medical College and Research Institute, Mysore -570001, Karnataka, India
2Professor and Head, Department of Pediatrics, Bangalore Medical College and Research Institute, Bangalore - 560002, Karnataka.
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Pediatrics, Mysore Medical College and Research Institute, Mysore -570001, Karnataka, India
Department of Pediatrics, Bangalore Medical College and Research Institute, Bangalore - 560002, Karnataka, India
Abstract
Epidermolysis bullosa (EB) represents a rare, heterogenous group of genetically determined skin disorders manifested by an exceptional tendency of the skin and mucous membranes to form bullae and vesicles either spontaneously or as a result of mechanical trauma/friction. EB has been classified on genetic, clinical, and histological criteria into several distinct categories of which the three major subgroups are Epidermolysis bullosa simplex, junctional epidermolysis bullosa and dystrophic epidermolysis bullosa (DEB). Both autosomal dominant and recessive forms have been described in DEB. Ineffective or absent connective tissue anchoring fibrils, resulting in a loosely bound epithelial/subepithelial connective tissue interface results in this disorder. Autosomal recessive form of DEB is a rare form of EB characterized by a generalized blistering rash involving the entire skin and almost all mucous membranes. It manifests in the early neonatal period and is usually fatal. We report a 13 day old neonate who presented to us with clinical features consistent with recessive form of DEB.
Keywords: Anchoring fibrils; bullae; epidermolysis bullosa; vesicles.
*To whom it corresponds:-
Dr. Girish Gopal;
Senior Resident,
Department of Pediatrics, Mysore Medical College & Research Institute, Irwin Road, Mysore – 570001, India
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Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Article citation:
Girish G,Belavadi GB. Dystrophic Epidermolysis Bullosa in the newborn. J Pharm Biomed Sci 2014;04(05):434-438. Available at www.jpbms.info.
Copyright © 2014 Girish G,Belavadi GB. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.