DocumentsDate added
Research Article
Gulsheen Kaur Kochhar1,*,Prinka Shahi2,Shweta Advani3, Preetinder Singh4,Sumit Kaushal4,Tanu Nangia5
Affiliation:-
1Assistant Professor, Department of Pedodontics & Preventive Dentistry, Swami Devi Dyal Hospital & Dental College, Barwala, Panchkula, Haryana, India
2Assistant Professor,Department of Pedodontics & Preventive Dentistry. MM College of Dental Sciences and Research Centre, Ambala, Haryana, India
3Senior Faculty & Academic Advisor, Aim MDS
4Associate Professor, Department of Periodontics & Implantology, Swami Devi Dyal Hospital & Dental College, Barwala, Panchkula, Haryana, India
5Assistant Professor, Department of Pedodontics & Preventive Dentistry, MPCDC,Gwalior,India
The name of the department(s) and institution(s) to which the work should be attributed:
1.Department of Pedodontics & Preventive Dentistry, Swami Devi Dyal Hospital & Dental College, Barwala, Panchkula, Haryana, India
2. Department of Pedodontics & Preventive Dentistry, MM College of Dental Sciences and Research Centre, Ambala, Haryana, India
2. Department of Periodontics & Implantology, Swami Devi Dyal Hospital & Dental College, Barwala, Panchkula, Haryana, India
3. Department of Pedodontics & Preventive Dentistry, MPCDC, Gwalior, India
Authors contributions:
All the authors contributed equally to this paper.
Address reprint requests to
* Dr. Gulsheen Kaur Kochhar .
Assistant Professor,
Department of Pedodontics & Preventive Dentistry, Swami Devi Dyal Hospital & Dental College Barwala, Haryana
Article citation:
Kochhar GK,Shahi P,Advani S,Singh P, Kaushal S,Nangia T. Dermatoglyphics of dental caries and Periodontal diseases in Children of North India. J Pharm Biomed Sci 2014;04(07):658-663.Available at www.jpbms.info
ABSTRACT
To determine the correlation between dermatoglyphics and the infectious oral diseases and to estimate dermatoglyphic dependence of dental caries and periodontal diseases in children of North India. 99 children (12-14 years) were divided in two groups; Group A for Caries Assessment And Group B For Gingival And Periodontal Assessment. Dermatoglyphic patterns of all 10 palmar digits were recorded using Cummins and Midlo method. Frequency distribution for dermatoglyphic peculiarities data in 99 children for caries assessment and gingival and periodontal assessment were tabulated. ANOVA test was applied for significance. ANOVA test revealed a highly significant difference was observed between the three groups of caries with loops and a significant difference P value : <0.005 (whorls) in caries assessment group. Whereas it was observed that between the three groups of OHI with loops and a no significant difference. An increase in whorls and decrease in loops with increase in caries and decrease in loops and no significant relationship with whorls with increase in periodontal diseases.
KEYWORDS: Dermatoglyphics; Caries; Periodontal Diseases; Children.
REFERENCES
1.Blanka Schaumann, Milton, Alter. Dermatoglyphics in medical disorders, Springer- Verlage. New York, Heldel berg, Berlin, 1976.
2.Cummins H, Midlo C. Finger prints, palms and soles. Dower publications. Newyork 55-66, 74-78, 108, 1961.
3.Mathew L,Hegde AM, Rai K. Dermatoglyphic findings in oral clefts. JISPPD 2006; 23:179-82
4.Cummins. Revised methods of interpretation and formulation of palmar dermatoglyphics. Am J Phy Anthr 1928; 12:415-502.
5.Metin Atasu. Dermatoglyphic findings in dental caries: a preliminary report.J Clin Pediatr Dent 1998; 22(2): 147-149.
6.Cummins. Study of error in interpretation and formulation of palmar dermatoglyphics. Am J Phy Anthr 1928; 11: 501-512
7.Joel S. Fingerprints of palms and soles: Evidence. 1st edition. Lippicott publications. Dermatoglyphic interpretation of dental caries and itscorrelation to salivary bacteria interactions: An in vivo study. A Sharma, R Somani. JISSPD 2009; 27(1): 17-21.
Copyright © 2014 Kochhar GK,Shahi P,Advani S,Singh P, Kaushal S,Nangia T. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclosure forms provided by the authors are available with the full text of this article at jpbms.info
Original article
Chethana. K.V*, Abhay Mane1, S.G.Hiremath2, Revathi3, Sreejith.S.Nair4
Affiliation:-
*Post Graduate student; 1Professor; 2Professor & HOD; 3Assistant Professor; 4Post Gradutate, Department of Community Medicine; Navodaya Medical College; Raichur; Karnataka, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Community Medicine; Navodaya Medical College; Raichur; Karnataka, India
Address reprint requests to
Dr. Chethana.K.V.
Post Graduate,
Department of Community Medicine,
Navodaya Medical College, Raichur- 584103
Karnataka; India or at chetuvb09@gmail.com
J Pharm Biomed Sci 2014;04(06):581-587.
Article citation:
Chethana KV,Mane A,Hiremath SG,Revathi,Nair SS. Determinants and practices of hand hygiene among school going children in rural and urban area of raichur. J Pharm Biomed Sci 2014; 04(07):581-587. Available at www.jpbms.info
ABSTRACT
According to the World Health Organization unsafe water, inadequate sanitation, and insufficient hygiene account for an estimated 9.1% of the global burden of disease and 6.3% of all deaths. Good hand washing practice is a prerequisite to a child’s survival. The high incidence of diarrheal diseases and other communicable diseases among school children may be due to poor knowledge and practice of personal and environmental hygiene. Poor knowledge and practice of, and attitudes to personal hygiene, such as hand washing, has negative consequences for a child’s long term overall development.
Objectives: To study the determinants and practices of hand hygiene among school going children in rural and urban area of Raichur.
Methodology: Cross-sectional study was undertaken in the Urban and Rural field practice area of Navodaya Medical College, Raichur,from 8th to 28th July 2013. Informed consent was taken from the Principal of the school and parents for examination of students. All the students who were present were examined. Data was analyzed using SPSS version 17.0 statistical software.
Results: Total 676 students participated in the study, 293 were (43.3%) urban and 383 (56.7%) from rural areas.In rural areas, the followed method of defecation was open place by 88.5% students as compared to only 22% in urban areas. Majority, 79.5% students in rural areas reported no access to soap as compared to 23.5% students in urban areas. The access to water for handwash inside the home was significantly less (83.6%) among students from rural area as compared to urban area (94.2%).
KEYWORDS: Hand Hygiene; rural; urban; school children.
Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclosure forms provided by the authors are available with the full text of this article at jpbms.info
REFERENCES
1.Pruss-Ustun A, Bos R, Gore F, Bartram J. Safer water, better health: costs, benefits and sustainability of interventions to protect and promote health. World Health Organization, Geneva; 2008.
2.Hoque, B.A., 2003. Handwashing practices and challenges in Bangladesh. Int. J. Environ. Health Res., 13(Suppl 1): S81-S87.
3.Best M, Neuhauser D. Ignaz Semmelweis and the birth of infection control. Qual Saf Health Care 2004; 13:233-4.
4.Curtis V. and Cairncross. 2003. Effect of washing hands with soap on diarrhoea risk in the community: a systematic review The Lancet Infectious Diseases 2003; 3: 275-81.
5.Luby, S. P., M. Agboatwalla, J. Painter, A. Altaf, W.L. Billhimer, and R.M. Hoekstra. 2004. Effect of intensive handwashing promotion on childhood diarrhea in high-risk communities in Pakistan: A randomized controlled trial. Journal of the American Medical Association 291: 2547-54.
6.Ray SK, Dobe M, Maji S, Chakraborty D, Sinha Roy AK, Basu SS. A pilot survey on hand washing among some communities of West Bengal. Indian J Public Health 2006; 50: 225-30.
7.World Bank, EHP, WSP: Handwashing Consumer Research Reports:Ghana, Peru, Senegal.
8.UNICEF, 2008.The State of the World’s Children 2008. Child Survival. Children as Agents of Change: Lessons from UNICEF. Retrieved from: http://www.globalhandwashingday.org/Lessons_UNICEF.asp,
Copyright © 2014 Chethana KV, Mane A, Hiremath SG, Revathi, Nair SS. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article:
Huisu Wu, Wei Li, Yewei Sun, Lipeng Xu, Pei Yu, Yuqiang Wang, Zaijun Zhang*
Affiliation:-
Institute of New Drug Research and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine, Jinan University College of Pharmacy, Guangzhou 510632, China
The name of the department(s) and institution(s) to which the work should be attributed:
Institute of New Drug Research and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine, Jinan University College of Pharmacy, Guangzhou 510632, China
Address reprint requests to
Zaijun Zhang
Institute of New Drug Research and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine, Jinan University College of Pharmacy, Guangzhou 510632, China
Tel.: +8620-8522-5030; Fax: +8620-8522-5030.
J Pharm Biomed Sci 2014;04(07):573-580.
Article citation:
Huisu Wu , Wei Li, Yewei Sun, Lipeng Xu, Pei Yu, Yuqiang Wang et al. Determination of AL-1 in rat plasma and tissues by high-performance liquid chromatography and its application in AL-1 pharmacokinetic study. J Pharm Biomed Sci 2014;04(07):573-580. Available at www.jpbms.info
ABSTRACT
A simple and rapid method based on high-performance liquid chromatography (HPLC) for the quantitative determination of AL-1 in rat plasma and tissues has been developed and validated. Rhein was selected as the internal standard. Chromatographic separation was carried out on a Kromasil C18 column (250 mm×4.6 mm, 5 m) using a mixture of methanol-PBS solution (77:23, v/v) as the mobile phase at a flow rate of 1 ml/min with detection at 234 nm wavelength. The linearity ranged from 0.025 to 160 µg/ml and the lower limit of quantification was estimated as 0.025 µg/ml. The intra-day and inter-day precisions were in the range of 1.72~7.81% and 0.8~9.23%, respectively. The extraction recovery was 65.23±5.61% and 82.63±1.31% in plasma and tissues. The validated method may be used to assess pharmacokinetics and tissues distribution of the drug.
KEYWORDS: AL-1; HPLC; plasma; pharmacokinetics; tissues distribution.
Source of support: This work is partially supported by grants from the National Natural Science Foundation of China (U1032007 to YW, NSFC 81001683 to LX, and NSFC 81303251 to ZZ), China’s ‘12.5’ Innovative Drug Project (2012ZX09103101-055 to YW) as well as the Municipal Science and Technology Project of Guangdong (2012A080201009 to YW) and the International Science and Technology Collaborative Project of Guangdong Department of Education (gjhz1102 to YW). This work is also supported in part by the China Postdoctoral Science Foundation (2013M531911 to ZZ), as well as the Scientific Research Starting Foundation for Returned Overseas Chinese Scholars (23610008 to LX), Ministry of Education, China; and the Specialized Research Fund for the Doctoral Program of Higher Education (20104401120003 to LX).
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Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Research Article:
Ashima Badyal1,*.,MD,Rajesh Pandey2.,MD,Kuldeep Singh Sodhi3.,MD,Jasbir Singh4.,MD
Affiliation:-
1Badyal Ashima*, MD Biochemistry, Registrar, Department of Biochemistry, GMC, Jammu, J&K,India
2Pandey Rajesh, MD Biochemistry, Professor, Department of Biochemistry, MMIMSR, Mullana,Ambala, Haryana,India
3Sodhi Kuldeep S, MD Biochemistry, Professor, Department of Biochemistry, MMIMSR, Mullana, Ambala, Haryana, India
4Singh Jasbir, MD Biochemistry, Professor and Head, Department of Biochemistry, MMIMSR, Mullana, Ambala, Haryana, India
The name of the department(s) and institution(s) to which the work should be attributed:
1.Department of Biochemistry, GMC, Jammu, J&K,India
2.Department of Biochemistry, MMIMSR, Mullana, Ambala, Haryana,India
Address reprint requests to
Ashima Badyal.
214-A Shastri Nagar, Jammu, J&K State, India- 180004 or at badyal.ashima@gmail.com
Article citation:
Badyal A, Pandey R,Sodi KS,Singh J. Evaluation of Serum Magnesium in Patients with Complicated Type 2 Diabetes Mellitus. J Pharm Biomed Sci 2014; 04(07):596-599. Available at www.jpbms.info
ABSTRACT
Context: Hypomagnesemia has been implicated in adversely affecting diabetic complications.
Several studies have demonstrated a higher than expected frequency of magnesium deficiency in patients with diabetes mellitus. Lack of accurate screening methodology is one of the main problems in assessing total body magnesium status.
Aims: To compare serum magnesium levels in type 2 diabetic patients with complications with those of non-diabetic controls and to assess the relationship between these two.
Setting and Design: Prospective cross sectional study in rural setting of Haryana.
Material and Methods: Fifty healthy controls and 100 patients with type 2 diabetes mellitus with complications were recruited from Medicine OPD of MMIMSR, Mullana, Ambala (Haryana), and their serum glucose and serum magnesium levels were measured and compared.
Statistical analysis: By SPSS version 12 [SPSS v12 (SPSS Inc., Chicago, IL)].
Results: Serum magnesium levels are decreased in type 2 diabetes mellitus with complications.
Conclusion: The early determination of magnesium status should be implemented in clinical practice for the better management of complicated diabetes mellitus.
KEYWORDS: Complications; magnesium; type 2 diabetes mellitus.
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17.Badyal A, Pandey R, Sodhi KS, Singh J. Decreased Serum Magnesium in patients with uncomplicated Type 2 Diabetes Mellitus. J Pharm Biomed Sci 2014; 4(3):361-64.
Copyright © 2014 Badyal A, Pandey R,Sodi KS,Singh J. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclosure forms provided by the authors are available with the full text of this article at jpbms.info
Research article
Ahmed, Abdalhameed1,*, M. & Elhag.Wafa,1,PhD
Affiliation:-
1MSc. Student, Faculty of Medical Laboratory Sciences-AL-Neelain University, Khartoum, Sudan.
2Assistant professor, Microbiology department, Faculty of Medical Laboratory Sciences-AL-Neelain University, Khartoum, Sudan
The name of the department(s) and institution(s) to which the work should be attributed:
Faculty of Medical Laboratory Sciences-AL-Neelain University, Khartoum, Sudan
Authors contributions:
Study idea, design, practical, analysis, writing of manuscript and editing all by author 1 and the supervising of research, and revising of paper by author 2.
Address reprint requests to
* Ahmed, Abdalhameed,
Faculty of Medical Laboratory Sciences-AL-Neelain University, Khartoum, Sudan
Article citation:
Abdalhameed A & Wafa E. Frequency of Hepatitis A virus among food handlers. J Pharm Biomed Sci 2014;04(07):664-669. Available at www.jpbms.info
ABSTRACT
Objectives: The aim of this study was to determine the frequency of the hepatitis A virus (HAV) in food handlers in Khartoum state, Sudan during period March to June 2014.
Materials & methods: A total of ninety food handlers, were enrolled in this study. Out of them 85 (94.4 %) were males and 5 (5.6%) females, and their age ranged between 30 to 39 with mean age of 33 years.
Blood specimens were collected and examined by ELISA technique for the detection of hepatitis A IgM& IgG antibodies.
Results: IgM antibody was detected among 6(6.7%) food handlers, while 32(35.6%) food handlers had IgG antibody, and 2.0 (3.6%) were positive for both. Most of seropositive were males 6(6.7%) IgM & 30 (33.3%)IgG,
Conclusion: The frequency of HAV IgM& IgG among the Food handlers is high in the age group (40-49) & (20-29) respectively. Education for behaviors along with screening, vaccination, and appropriate treatment for hepatitis A is strongly recommended to control this persistent infectious source of hepatitis A in the community.
KEYWORDS: HAV; food handlers; ELISA technique.
Core tip: - A critical problem for food handlers is hepatitis A infections. Some of the risk factors associated with HAV infection include poor hygiene, poor sanitation, and food & water contamination. In fact, HAV infection through food handlers has increased worldwide.
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