DocumentsDate added
Original article:
Kapil Srivastava1,*, Anil Bidwai2, Dhiraj Srivastava3, Ramesh Thanna4
Affiliation:-
1Ex Post Graduate Student, 2Professor,3MD,Assistant Professor, 4Msc,Department of Biochemistry, Index Medical College, Indore, Madhya Pradesh, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Biochemistry, Index Medical College, Indore, Madhya Pradesh, India
Address reprint requests to
Dr. Kapil Srivastava.
Kamaleshwar colony, Dabra, Gwalior ,Madhya Pradesh, India or at kapilgrmc@gmail.com
Article citation:
Srivastava K,Bidwai A,Shrivastava D,Thanna R. A study to assess lipid profile values in atheroscerotic patients of different age and sex groups. J Pharm Biomed Sci. 2014;04(09):A1-A7. Available at www.jpbms.info
ABSTRACT
Background: Atherosclerosis, also called hardening or blockage of the arteries, is a very common condition affecting the arteries, the thick-walled, high-pressure blood vessels that carry fresh oxygen-rich blood from the heart to the rest of the body.
Atherosclerosis occurs more frequently in men than in women. There have been studies that show the sex gap in plaque prevalence is strongly influenced by age. Objectives: Estimation of serum lipid profile in normal–male, female–healthy controls and atherosclerosis patients (male & female).
Comparison above biochemical parameters between normal male healthy control and male atherosclerosis patients (30 – 50 year & 51 – 70 year) Methodology: A Total of 53 patients full filing exclusion and inclusion criteria’s were included in the study group and 50 ages matched male and female healthy individual control groups during the period one year. Blood samples were collected from the patients and male and female healthy individual controls. This blood used for separation of serum. Serum used for estimation of lipid profile.
Results: There is significant difference in the biochemical parameters values between normal male and female healthy controls and male and female Atherosclerosis patients. There is no significant difference in the vales of serum cholesterol in both male and female atherosclerotic patients.
Conclusion: The present study hereby concludes that in comparison to normal healthy controls, atherosclerotic patients have higher serum values of TC, LDL, and TG and lower values of HDI cholesterol.
KEYWORDS: Atherosclerosis, Lipid Profile, Atherosclerotic diseases
REFERENCES
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Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Research article:
Asha A Dharwadkar*, Bindu. C.B, Anand R Dharwadkar
Affiliation:-
Professor, Department of Physiology, Amala Institute of Medical Sciences, Thrissur, Kerala,India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Physiology, Amala Institute of Medical Sciences, Thrissur, Kerala,India
Address reprint requests to
*Dr.Asha A.Dharwadkar.
Professor, Department of Physiology, Amala Institute of Medical Sciences, Thrissur, Kerala, India
Article citation:
Dharwadkar AA,Chenmarathy BB,Dharwadkar AR. A Comparative Study of breath holding time as an Index of Central Ventilatory Response in young Healthy Adults of both Sexes. J Pharm Biomed Sci. 2014; 04(09):806-812. Available at www.jpbms.info
ABSTRACT
Relationship of anthropometrical parameters & sex to BHT is not reported in any studies done so far. A comparative study was carried out to evaluate Breath holding time [BHT] upto breakpoint as an index of central ventilatory response in young healthy adults of both sexes[n=99; female 59; male 40]. The anthropometrical parameters, resting RR [breaths/min] & BHT [ seconds] after deep inspiration upto break point were recorded before & after deep breathing session [i.e. at the rate of 6 breaths /min for 5 minutes].Statistical analysis was done with the help of SPSS 16th version by both Paired& Unpaired Students’ ‘t’ test; and correlation. P<0.05 is considered as significant.It is observed that BHT measured at Total lung capacity did not show any correlation to anthropometrical parameters like Height [cms], Weight [Kgs], BSA [m2], BMI [kg/m2] either in females or males on separate analysis. The proportionately decreased BHT in females, in both recordings taken before & after deep breathing session, indicates increased sensitivity of respiratory center in females, attributable to oestrogen primed progesterone action. Normal RR with decreased BHT indicates the possibility of the renal regulatory mechanisms trying to maintain a state of chronic respiratory alkalosis in females. Awareness of the presence of Chronic respiratory alkalosis status existing in normal young females, more so during pregnancy, may help clinicians for better evaluation & management. So BHT [at TLC] & Respiratory rate together may act as an index of central ventilatory response, inturn the sensitivity of respiratory center.
KEYWORDS: Anthropometry; Body mass index; Body weight; Break point; Breath holding; Central ventilatory response; Progesterone; Respiratory center.
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ABBREVIATIONS:
Respiratory rate[RR], Breath holding time [BHT],Total lung capacity[TLC].
Copyright © 2014 Dharwadkar AA,Chenmarathy BB,Dharwadkar AR. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.