DocumentsDate added
Research article:
Asha A Dharwadkar*, Bindu. C.B, Anand R Dharwadkar
Affiliation:-
Professor, Department of Physiology, Amala Institute of Medical Sciences, Thrissur, Kerala,India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Physiology, Amala Institute of Medical Sciences, Thrissur, Kerala,India
Address reprint requests to
*Dr.Asha A.Dharwadkar.
Professor, Department of Physiology, Amala Institute of Medical Sciences, Thrissur, Kerala, India
Article citation:
Dharwadkar AA,Chenmarathy BB,Dharwadkar AR. A Comparative Study of breath holding time as an Index of Central Ventilatory Response in young Healthy Adults of both Sexes. J Pharm Biomed Sci. 2014; 04(09):806-812. Available at www.jpbms.info
ABSTRACT
Relationship of anthropometrical parameters & sex to BHT is not reported in any studies done so far. A comparative study was carried out to evaluate Breath holding time [BHT] upto breakpoint as an index of central ventilatory response in young healthy adults of both sexes[n=99; female 59; male 40]. The anthropometrical parameters, resting RR [breaths/min] & BHT [ seconds] after deep inspiration upto break point were recorded before & after deep breathing session [i.e. at the rate of 6 breaths /min for 5 minutes].Statistical analysis was done with the help of SPSS 16th version by both Paired& Unpaired Students’ ‘t’ test; and correlation. P<0.05 is considered as significant.It is observed that BHT measured at Total lung capacity did not show any correlation to anthropometrical parameters like Height [cms], Weight [Kgs], BSA [m2], BMI [kg/m2] either in females or males on separate analysis. The proportionately decreased BHT in females, in both recordings taken before & after deep breathing session, indicates increased sensitivity of respiratory center in females, attributable to oestrogen primed progesterone action. Normal RR with decreased BHT indicates the possibility of the renal regulatory mechanisms trying to maintain a state of chronic respiratory alkalosis in females. Awareness of the presence of Chronic respiratory alkalosis status existing in normal young females, more so during pregnancy, may help clinicians for better evaluation & management. So BHT [at TLC] & Respiratory rate together may act as an index of central ventilatory response, inturn the sensitivity of respiratory center.
KEYWORDS: Anthropometry; Body mass index; Body weight; Break point; Breath holding; Central ventilatory response; Progesterone; Respiratory center.
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ABBREVIATIONS:
Respiratory rate[RR], Breath holding time [BHT],Total lung capacity[TLC].
Copyright © 2014 Dharwadkar AA,Chenmarathy BB,Dharwadkar AR. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article:
Kapil Srivastava1,*, Anil Bidwai2, Dhiraj Srivastava3, Ramesh Thanna4
Affiliation:-
1Ex Post Graduate Student, 2Professor,3MD,Assistant Professor, 4Msc,Department of Biochemistry, Index Medical College, Indore, Madhya Pradesh, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Biochemistry, Index Medical College, Indore, Madhya Pradesh, India
Address reprint requests to
Dr. Kapil Srivastava.
Kamaleshwar colony, Dabra, Gwalior ,Madhya Pradesh, India or at kapilgrmc@gmail.com
Article citation:
Srivastava K,Bidwai A,Shrivastava D,Thanna R. A study to assess lipid profile values in atheroscerotic patients of different age and sex groups. J Pharm Biomed Sci. 2014;04(09):A1-A7. Available at www.jpbms.info
ABSTRACT
Background: Atherosclerosis, also called hardening or blockage of the arteries, is a very common condition affecting the arteries, the thick-walled, high-pressure blood vessels that carry fresh oxygen-rich blood from the heart to the rest of the body.
Atherosclerosis occurs more frequently in men than in women. There have been studies that show the sex gap in plaque prevalence is strongly influenced by age. Objectives: Estimation of serum lipid profile in normal–male, female–healthy controls and atherosclerosis patients (male & female).
Comparison above biochemical parameters between normal male healthy control and male atherosclerosis patients (30 – 50 year & 51 – 70 year) Methodology: A Total of 53 patients full filing exclusion and inclusion criteria’s were included in the study group and 50 ages matched male and female healthy individual control groups during the period one year. Blood samples were collected from the patients and male and female healthy individual controls. This blood used for separation of serum. Serum used for estimation of lipid profile.
Results: There is significant difference in the biochemical parameters values between normal male and female healthy controls and male and female Atherosclerosis patients. There is no significant difference in the vales of serum cholesterol in both male and female atherosclerotic patients.
Conclusion: The present study hereby concludes that in comparison to normal healthy controls, atherosclerotic patients have higher serum values of TC, LDL, and TG and lower values of HDI cholesterol.
KEYWORDS: Atherosclerosis, Lipid Profile, Atherosclerotic diseases
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Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Review article:
Mwahib Sid Ahmed Mohamed Osman Aldosh*
Affiliation:-
Assistant Professor, Radiological Sciences Department Applied Medical College - Najran University- Kingdom of Saudi Arabia
The name of the department(s) and institution(s) to which the work should be attributed:
Radiological Sciences Department Applied Medical College - Najran University- Kingdom of Saudi Arabia
Address reprint requests to
Dr. Mwahib Sid Ahmed Mohamed Osman Aldosh ,Ph.D
Assistant Professor, Radiological Sciences Department Applied Medical College-Najran University- Kingdom of Saudi Arabia
Article citation:
Mwahib A. Applications of Nanoparticles in Biomedical. J Pharm Biomed Sci. 2014;04(09):743-750. Available at www.jpbms.info
ABSTRACT
The application of nanomaterials for cancer therapy and for early diagnosis of pathologies has received considerable attention in recent years. Particularly in the field of biomedical with extensive applications. The wide interdisciplinary world of Nanoscience was experiencing a strong development during the last years. One exciting topic is the possibility of using nanoscale materials for biomedical applications. The application of nanotechnology to medicine, known as nanomedicine, concerns the use of precisely engineered materials at this length scale to develop novel therapeutic and diagnostic modalities. Recent improvements in engineering at the nanoscale level have lead to the development of a variety of new, novel nanoscale platforms (quantum dots, nanoshells, gold nanoparticles, paramagnetic nanoparticles, carbon nanotubes), which currently are under development and has profoundly studied. The emerging roles of these wide variety of applications, in biomedical imaging and therapeutic are the focus of this research, in addition to describing how nanoparticles can be used for targeted imaging and delivery of therapeutic agents and identify and discuss strategies to circumvent barriers to intratumoral delivery of nanoparticles.
KEYWORDS: Nanoparticles; applications; magnetic resonance imaging; cancer therapy; diagnostic imaging; drug deliver.
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Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclosure forms provided by the authors are available with the full text of this article at jpbms.info
Copyright © 2014 Mwahib A. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Niraj Kumar Biswas1,*,Parimal H Patel2,Hitesh R Ahir3,Purvi H Kothadia3,Alka B Nerurkar4
Affiliation:-
1Associate Professor, 2Assistant Professor, 3Tutor,4Professor and Head, Department of Microbiology, GMERS Medical College, Valsad, Gujarat, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Microbiology, GMERS Medical College, Valsad,Gujarat, India
Address reprint requests to
Dr.Niraj KUmar Biswas.
Associate Professor, Department of Microbiology, GMERS Medical College, Valsad, Gujarat, India
Article citation:
Biswas NK,Patel PH,Ahir HR,Kothadia PH,Nerurkar AB. Bacteriological profile of Urinary tract infection and its antibiotic susceptibility at tertiary care Hospital, Valsad, Gujarat,India. J Pharm Biomed Sci. 2014; 04(09):751-754. Available at www.jpbms.info
ABSTRACT
Objective:This study was done to find out the common bacteria causing UTI and to determine the antibiotic susceptibility pattern of the urinary pathogens in patients attending a tertiary care hospital in Valsad, Gujarat.
Material and Methods: In duration of January to July 2014, 179 urine samples were collected from patients of suspected UTI, Collected samples were inoculated on sheep Blood agar, Mac Conkey agar and Nutrient agar and incubated at 37°C by using standard method and antibiotic susceptibility test were performed by Kirby Bauer disc diffusion method.
Results: 76(42.45%) samples were found to be positive in a culture in which 60 (78.95%) were gram negative, 13(17.10%) were Gram positive and 3 (3.95%) were candida spp. Maximum number of organisms isolated were E.coli, followed by Klebsiella sp., Pseudomonas sp. Enterococcus sp, Candida and other organisms. Isolated organisms show more resistance to commonly used antibiotics.
Conclusion: Gram negative bacilli are the commonly isolated organisms in UTI and E.coli is most common of them. An isolated organism shows more resistance to commonly used antibiotics.
KEYWORDS: UTI; Antibiotic susceptibility; urinary pathogens.
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Copyright © 2014 Biswas NK,Patel PH,Ahir HR,Kothadia PH,Nerurkar AB. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Competing interest / Conflict of interest: None
Research article:
Delgado, E.A.D.1, Fonseca JR., J.H.2, Gibertoni, F.2, Beretta, A.L.R.Z3,*
Affiliation:-
1Student-Specialization in Clinical Analysis University Center Hermínio Ometto (UNIARARAS) Araras, S.P.
2Masters Student - Graduate Program - Biomedical Sciences Center Hermínio Ometto (UNIARARAS), Araras, S.P.
3* Doctor-teacher of the Graduate Program in Biomedical Sciences, University Center Hermínio Ometto (UNIARARAS), Araras, SP, Brasil
The name of the department(s) and institution(s) to which the work should be attributed:
Microbiological Research Laboratory, Av. Dr. Maximiliano Baruto, 500 Jd. Universitário. 13607-339 - Araras – SP – Brasil
Address reprint requests to
Ana Laura Remédio Zeni Beretta
Microbiological Research Laboratory, Av. Dr. Maximiliano Baruto, 500 Jd. Universitário. 13607-339 - Araras – SP – Brasil
Article citation:
Delgado, E.A.D., Fonseca JR., J.H., Gibertoni, F., Beretta, A.L.R.Z. Biosafety and the tuberculosis in units of health. J Pharm Biomed Sci. 2014; 04(09):769-772. Available at www.jpbms.info
ABSTRACT
Tuberculosis is an infectious disease of worldwide extent, caused by Mycobacterium tuberculosis and its transmission has always been a frequent concern in healthcare services. With the growth of strains resistant to first-line antituberculosis drugs and the emergence of Acquired Immune Deficiency Syndrome have made this more intense concern.
Objectives: Through exploratory study of articles and books published in the databases LILACS, MEDLINE, thesis database, aimed to identify the risks of health professionals for the occurrence of pulmonary tuberculosis and demonstrate the behaviors of these biosafety professionals exposed to M. tuberculosis.
Results: Due to the large number of infected people and the high risk of movement of persons affected by the disease, biosecurity should function as an effective ally, through action plans and control in health care institutions.
Conclusion: Based on the data, the study suggests that health professionals are at risk because of the limitations found with regard to preventive measures, especially the delayed diagnosis of tuberculosis. It is extremely important to implement biosecurity measures in health facilities, as well as the investigation of pulmonary tuberculosis, since these professionals are unaware of the occupational risks.
KEYWORDS: Pulmonary tuberculosis, health professionals, occupational risk; Biosafety.
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Copyright © 2014 Delgado, E.A.D., Fonseca JR., J.H., Gibertoni, F., Beretta, A.L.R.Z. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript