DocumentsDate added
Original article
Anju Ade1,*, Shivanand V H2, Ramesh Patil3
Affiliation:-
1Associate professor, Department of Community Medicine, Navodaya Medical College, Raichur, Karnataka-584103, India
2Lecturer in NET Pharmacy College, Raichur, Karnataka-584103, India
3Assistant Professor (Statistics), Ashwini Medical College, Solapur, India
The name of the department(s) and institution(s) to which the work should be attributed:
1.Department of Community Medicine, Navodaya Medical College, Raichur, Karnataka-584103, India
2.NET Pharmacy College, Raichur, Karnataka-584103, India
Address reprint requests to
Dr Anju Ade,
Associate professor,
Community Medicine Department, Navodaya Medical College, Raichur, Karnataka-584103, India
Article citation:
Ade A,Shivanand V H,Patil R. Nutritional status of rural school children in Raichur District, Karnataka,India. J Pharm Biomed Sci. 2014;04(09):781-785. Available at www.jpbms.info
ABSTRACT
For this study,we calculated the Body Mass Index (BMI) of school children to assess their nutritional status. A total of 299 school children were present during the visit. Out of these students, 105(45.9%) were males and 124(54.1%) were females with high rates of thinness of 101(96.19%) and 116(93.54%) in boys and girls respectively. Socio-demographic factors like education of father, monthly family income and housing were significantly associated with nutritional status of children.
KEYWORDS: Anthropometry; Nutritional status; Rural children; Body mass index.
Source of support: None
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Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Ade A, Shivanand V H, Patil R. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Samavedam Srinivasa Sarma1,Pennagaram Sarguna2,*
Affiliation:-
1Assistant Professor, 2Associate Professor, Department of Microbiology, Rangaraya Medical College, Kakinada-533005, A.P,India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Microbiology, Rangaraya Medical College, Kakinada-533005, A.P, India
Address reprint requests to
Dr.Pennagaram Sarguna,
Associate Professor, Department of microbiology, Rangaraya Medical College, Kakinada, A.P.India
Core tip: The present study was undertaken to know the microbiological profile in corneal ulcers. Majority of the infections are caused by Staphylococcus aureus. The results of antibiotic susceptibility of bacterial isolates provide information to make rationale- based decision in choosing initial treatment regimen.
Article citation:
Sarma SS, Sarguna P Microbial Keratitis - A Prospective Study. J Pharm Biomed Sci. 2014;04(09):818-824.Available at www.jpbms.info
ABSTRACT
To study the epidemiological characteristics, microbiological profile, and in vitro antibiotic susceptibility results to make rationale - based decisions in choosing initial treatment regimen of bacterial keratitis. The hospital - based prospective study of 100 consecutive patients with corneal ulcers attending the outpatient department of Government General Hospital, Kakinada, Coastal A.P. from August 2011 through June 2013 were enrolled. Standard microbiologic evaluation of corneal scraping; smear examination and culture was done to establish the etiology. Attempt was made to study the microbial profile in 30 healthy conjunctival sac. Of 100 suspected cases of microbial keratitis, 59(59%) were culture proven; pure bacterial 41(41%), pure fungal 16(16%) and mixed infection in 2(2%). Majority of the bacterial infections were caused by Staphylococcus aureus (41.86%) and Aspergillus spp. (55.54%) was the leading cause of fungal keratitis. Most of the bacterial isolates were sensitive to aminoglycosides (72.09% - 95.34%) followed by cefotaxime (69.76%). The study shows that there is a region wise variation in the predominance of corneal pathogens. Routine surveillance of microbial keratitis is necessary to know the existing & emerging pathogens. This has an important public health implication for initiation of treatment, based on formulation of antimicrobial policy and management protocol to prevent visual morbidity.
KEYWORDS: Keratitis; bacteria; fungus; anti- bacterial susceptibility.
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21.Nikhil S Gokhale. Medical management approach to infectious keratitis. Indian J Ophthalmol 2008;56(3):215-220.
22.Jones DB. Decision making in the Management of microbial keratitis. Ophthalmology 1981;88:814-820.
Copyright © 2014 Srinivasa S, Sarguna P. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Research article:
Delgado, E.A.D.1, Fonseca JR., J.H.2, Gibertoni, F.2, Beretta, A.L.R.Z3,*
Affiliation:-
1Student-Specialization in Clinical Analysis University Center Hermínio Ometto (UNIARARAS) Araras, S.P.
2Masters Student - Graduate Program - Biomedical Sciences Center Hermínio Ometto (UNIARARAS), Araras, S.P.
3* Doctor-teacher of the Graduate Program in Biomedical Sciences, University Center Hermínio Ometto (UNIARARAS), Araras, SP, Brasil
The name of the department(s) and institution(s) to which the work should be attributed:
Microbiological Research Laboratory, Av. Dr. Maximiliano Baruto, 500 Jd. Universitário. 13607-339 - Araras – SP – Brasil
Address reprint requests to
Ana Laura Remédio Zeni Beretta
Microbiological Research Laboratory, Av. Dr. Maximiliano Baruto, 500 Jd. Universitário. 13607-339 - Araras – SP – Brasil
Article citation:
Delgado, E.A.D., Fonseca JR., J.H., Gibertoni, F., Beretta, A.L.R.Z. Biosafety and the tuberculosis in units of health. J Pharm Biomed Sci. 2014; 04(09):769-772. Available at www.jpbms.info
ABSTRACT
Tuberculosis is an infectious disease of worldwide extent, caused by Mycobacterium tuberculosis and its transmission has always been a frequent concern in healthcare services. With the growth of strains resistant to first-line antituberculosis drugs and the emergence of Acquired Immune Deficiency Syndrome have made this more intense concern.
Objectives: Through exploratory study of articles and books published in the databases LILACS, MEDLINE, thesis database, aimed to identify the risks of health professionals for the occurrence of pulmonary tuberculosis and demonstrate the behaviors of these biosafety professionals exposed to M. tuberculosis.
Results: Due to the large number of infected people and the high risk of movement of persons affected by the disease, biosecurity should function as an effective ally, through action plans and control in health care institutions.
Conclusion: Based on the data, the study suggests that health professionals are at risk because of the limitations found with regard to preventive measures, especially the delayed diagnosis of tuberculosis. It is extremely important to implement biosecurity measures in health facilities, as well as the investigation of pulmonary tuberculosis, since these professionals are unaware of the occupational risks.
KEYWORDS: Pulmonary tuberculosis, health professionals, occupational risk; Biosafety.
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Copyright © 2014 Delgado, E.A.D., Fonseca JR., J.H., Gibertoni, F., Beretta, A.L.R.Z. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript
Review article:
Mwahib Sid Ahmed Mohamed Osman Aldosh*
Affiliation:-
Assistant Professor, Radiological Sciences Department Applied Medical College - Najran University- Kingdom of Saudi Arabia
The name of the department(s) and institution(s) to which the work should be attributed:
Radiological Sciences Department Applied Medical College - Najran University- Kingdom of Saudi Arabia
Address reprint requests to
Dr. Mwahib Sid Ahmed Mohamed Osman Aldosh ,Ph.D
Assistant Professor, Radiological Sciences Department Applied Medical College-Najran University- Kingdom of Saudi Arabia
Article citation:
Mwahib A. Applications of Nanoparticles in Biomedical. J Pharm Biomed Sci. 2014;04(09):743-750. Available at www.jpbms.info
ABSTRACT
The application of nanomaterials for cancer therapy and for early diagnosis of pathologies has received considerable attention in recent years. Particularly in the field of biomedical with extensive applications. The wide interdisciplinary world of Nanoscience was experiencing a strong development during the last years. One exciting topic is the possibility of using nanoscale materials for biomedical applications. The application of nanotechnology to medicine, known as nanomedicine, concerns the use of precisely engineered materials at this length scale to develop novel therapeutic and diagnostic modalities. Recent improvements in engineering at the nanoscale level have lead to the development of a variety of new, novel nanoscale platforms (quantum dots, nanoshells, gold nanoparticles, paramagnetic nanoparticles, carbon nanotubes), which currently are under development and has profoundly studied. The emerging roles of these wide variety of applications, in biomedical imaging and therapeutic are the focus of this research, in addition to describing how nanoparticles can be used for targeted imaging and delivery of therapeutic agents and identify and discuss strategies to circumvent barriers to intratumoral delivery of nanoparticles.
KEYWORDS: Nanoparticles; applications; magnetic resonance imaging; cancer therapy; diagnostic imaging; drug deliver.
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Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclosure forms provided by the authors are available with the full text of this article at jpbms.info
Copyright © 2014 Mwahib A. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Mervat A. Ahmed1, Mona A. Mohamed2,*, Maha G. Soliman1,Yasmine H. Abd El-Naby3
Affiliation:-
1Zoology Department, 2Biochemistry division, 3Chemistry Department, Faculty of Science, Al-Azhar University for Girls, Egypt
3Military Clinics, Cairo, Egypt
The name of the department(s) and institution(s) to which the work should be attributed:
Faculty of Science, Al-Azhar University for Girls, Egypt
Address reprint requests to
Mona A. Mohamed.
Biochemistry division, Faculty of Science, Al-Azhar University for Girls, Egypt
Article citation:
Ahmed MA, Mohamed MA, Soliman MG, Abd Al-Naby YH. Monitoring The Expression Of Some Cell Adhesion Molecules And Serum Levels Of IL-6 And TNF-α In Irradiated Rats Treated With Wheat Germ Oil, Zinc And Bone Marrow. J Pharm Biomed Sci. 2014; 04(09):755-762. Available at www.jpbms.info
ABSTRACT
Background: Both radiotherapy and chemotherapy exert damaging effects on normal tissues in cancer patients and, consequently, induce an immune response in these tissues. Ionizing radiation in interaction with living cells causes a variety of changes depending on type of exposure, absorbed dose, duration of exposure, interval after exposure and also susceptibility of tissues. Aim: The present work was designed to evaluate the amelioration of serum IL-6 and TNF-α, in addition to expression of ICAM-1 and VCAM-1 genes in hepatic tissue of rats exposed to gamma radiation and treated with wheat germ oil and/or zinc sulfate individually or in combination with bone marrow transplanted cells.
Results: Exposure of rats to 5 Gy γ-rays (single dose) caused elevation in serum levels of MDA and IL-6, in addition to hepatic mRNA levels of ICAM-1 and VCAM-1 (62.2, 1.84-, 3.2- and 5.2- fold, respectively). On the other hand, levels of reduced glutathione and TNF-α were significantly lowered. Although administration of WG and Zn (either individually or in combination) improved the studied serum parameters, their levels were significantly different from control values. While hepatic mRNA levels of the adhesion molecules returned to near the control levels. Conclusion: Wheat germ oil and zinc in combination with bone marrow cells can be used as radioprotectors to improve the inflammatory status and disturbances in immune response induced by radiation.
Keywords:
KEYWORDS: Adhesion molecules; Inflammation; IL-6; Radiation; TNF-α.
Competing interest / Conflict of interest: None
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Copyright © 2014 Ahmed MA, Mohamed MA, Soliman MG, Abd Al-Naby YH. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Competing interest / Conflict of interest: None