DocumentsDate added
Original article
Namani Ganesh1,*,Dilip M Rampure1,Rajashekarappa1,¥
Affiliation:-
*1PG,1Professor and Head,1,¥Professor, Department of Medicine, Mamata Medical College,Khammam, Telangana state, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Medicine, Mamata Medical College,Khammam, Telangana state, India
Address reprint requests to
Dr. Ganesh Namani.
Postgraduate, Department of Medicine, Mamata Medical College,Khammam, Telangana state, India
Article citation:
Ganesh N,Rampure DM,Rajashekarappa. Etiological study of dilated cardiomyopathy in a tertiary care hospital. J Pharm Biomed Sci. 2014;04(10):910-913. Available at www.jpbms.info
ABSTRACT
Background: Dilated cardiomyopathy is an important cause of congestive heart failure and accounts for upto 25% of all cases of CHF. The incidence of DCM appears to be increasing and is associated with significant morbidity and mortality
Objective: To study the clinical, etiological, electrodiographic and echocardiographic profile of patients with DCM
Methods: A total of 50 patients who were admitted to a teaching hospital, Khammam and fulfilled the inclusion / exclusion criteria were evaluated by history, physical examination, ECG and echocardiography.
Results: Most of the patients affected were in the age group of 41-50 years. Males comprised 62% and females comprised 38%. Most of the cases are idiopathic. The clinical profile of patients included symptoms and signs of biventricular failure (80%) followed by left ventricular failure (16.6%).Left axis deviation, sinus tachycardia, ventricular premature complexes and ST – T changes were the common ECG findings. Echo showed reduced ejection fraction and global hypokinesia in all the patients. Biventricular dilatation was seen in 40 % of patients. Mitral regurgitation was seen in a significant number of patients (62%).
Conclusion: Dilated cardiomyopathy is a primary disease of the cardiac muscle and can occur at any age. Alcoholism and peripartum status are the most common identified etiologies. Biventricular failure was the most common clinical presentation. The clinical course is unpredictable and its interpretation is complicated by the difficulty in defining the onset of the disease.
KEYWORDS: Dilated cariomyopathy ; ECG; ECHO & Etiology.
REFERENCES
1.Zipes D, Libby P, Bonow R, Braunwald E. A Braunwald's heart disease -Textbook of Cardiovascular Medicine: Dilated cardiomyopathy. 9th Ed.Philadelphia: Elsivier Saunders;2012, pp.1563-69.
2.Anderson KM, Kannel WB. Prevalence of congestive heart failure in Framingham Heart study subjects. Circulation. 1994; 13 : S107-S112.
3.Vijayraghavan G. API Text book of medicine. Disorders of myocardium. 7th ed Chap X.25: 490-4914.
4.Alkesh Jain, Satyendra Tewari, Aditya Kapoor, Sudeep Kumar, Naveen Garg, PK Goel, Nakul Sinha . Clinical Profile of Dilated Cardiomyopathy. Indian Heart J. 2004; 56:374-382.
5.Yadav NA, Raghu K, LSR Krishna, Gouthami V, Jyotsana M, Seshagiri Rao D, Jaishankar S. Clinical Profile of Dilated Cardiomyopathy: A Tertiary Care Center Study. Indian Heart J. 2003; 55:165-178.
6.Gurpal singh, Prem Arora, SB Nayyar, JS Arora, BS Bal: A study of clinical profile of 124 cases of Dilated cardiomyopathy. Indian Heart J. 2001; 72:652-658.
7.Sachin C Hoskatti, Prakash K Phadnis, S. B Kalagate: Clinical Profile of patients with dilated cardiomyopathy. JAPI 2007;23:67-74.
8.Daniel WG, Nellessen U, Schroder E, et al. Left atrial spontaneous echo contrast in mitral valve disease: an indicator for an increased thromboembolic risk. J Am Coll Cardiol 11(1988), pp.1204-1211.
Source of support: None
Competing interest / Conflict of interest:
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Ganesh N,Rampure DM,Rajashekarappa. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article
Deepak Viswanath1,*,Madhumita Naithani2
Affiliation:-
1*Professor and Head,2Postgraduate Student, Department of Pedodontics and Preventive Dentistry, Krishnadevaraya College of Dental Sciences, Int. Airport Road, Hunasamaranahalli, Bangalore, India-562 157
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Pedodontics and Preventive Dentistry, Krishnadevaraya College of Dental Sciences, Int. Airport Road, Hunasamaranahalli, Bangalore, India-562 157.
Address reprint requests to
Dr.Deepak Viswanath,
Department of Pedodontics and Preventive Dentistry, Krishnadevaraya College of Dental Sciences ,Int. Airport Road, Hunasamaranahalli, Bangalore, India- 562 157
Article citation: Viswanath D, Naithani M. Evaluation of Night eating questionnaire (NEQ) used in residential and non residential school going adolescent population from Bangalore north: A comparative study. J Pharm Biomed Sci. 2014;04(10):904-909. Available at www.jpbms.info
ABSTRACT
Background: Night Eating Syndrome was first described in 1955 by Stunkard as an eating disorder that is characterised by morning anorexia, evening or nocturnal hyperphagia in a fully conscious state, and insomnia. Night Eating Questionnaire (NEQ) is an instrument designed to assess the severity of symptoms and to assist in identifying patient with Night Eating Syndrome.
Aims: The aim of our study was to decipher the prevalence of night eating syndrome using the night eating questionnaire in two subset population namely adolescents living at home and those living in hostel accommodation.
Settings and Design: The study was conducted in various day boarding and residential schools in Bangalore North.
Materials and Methods: 1235 adolescents in grades 6-10 were recruited for the study who were given the Night Eating Questionnaire to be filled up in front of the researcher. Additionally body weight and height were measured later for calculation of Body Mass Index for each subject.
Results: The Night Eating Syndrome was seen to be present in Indian adolescent population. Furthermore NES was observed to be more severe in residential population as compared to non residential population.
Conclusion: This representative cross sectional survey demonstrated the prevalence and severity of abnormal eating patterns in Indian adolescent population.
KEYWORDS: Adolescents; Eating Disorders; Night eating Syndrome; Obesity.
REFERENCES
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Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Viswanath D, Naithani M. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Sangita Chauhan1,*, M. L. Suhalka1,¥, Manjinder Kaur1,£
Affiliation:-
1M.D. Student,1,¥HOD,1,£Professor,Department of Physiology, Geetanjali Medical College & Hospital, Udaipur (Raj.), India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Physiology, Geetanjali Medical College & Hospital, Udaipur (Raj.), India
Address reprint requests to
Dr. Sangita Chauhan
Department of Physiology, Geetanjali Medical College & Hospital, Udaipur (Raj.),India
Article citation:
Chauhan S, Suhalka ML, Kaur Ml. A study of relationship between seminal fructose & infertility in man. J Pharm Biomed Sci. 2014; 04(09):926-929. Available at www.jpbms.info
ABSTRACT
Background: Fructose is secreted by the seminal vesicles which is the main source of energy and is responsible for the motility of the sperms. Lower level of seminal fructose has been observed in hypofunction of the seminal vesicles and has been a cause related to infertility in males.
Objectives: To find out relationship between seminal fructose concentration and sperm counts. Semen of 120 men having no disturbances in the seminal vesicular function were investigated.
Material and Methods: Semen was collected from normozoospermic, oligozoospermic and azoospermic men. Collection of Seminal fluid and its analysis was done using the WHO standards.
Results: 120 subjects were studied, out of which 20 were azoospermic, 50 were oligozoospermic and 50 were normozoospermic. Their ages ranged from 25-55 years. Estimation of sperm count and semen Fructose levels was done. The range of seminal fructose was determined and was correlated with the sperm concentration by Pearson correlation .By this study it was concluded that there is a correlation between seminal fructose and sperm concentration.
Conclusion: Seminal fructose could be used as important marker in testing infertility cases.
KEYWORDS: Seminal Fructose; Infertility; Sperm Concentration.
REFERENCES
1.Schirren C. Textbook of practical Andrology. Schireng A, G.Hamburg Germany. 1983 Pp.17–31..
2.Mann T. The Biochemistry of semen and of the male reproductive tract New York, NY: John Wiley & Sons Ipc; (1964).
3.Gonzales GF. Corrected seminal Fructose test Arc androl. (1994); 33:17-22 (Medline).
4.WHO Laboratory Manual for Examination of Human Semen and Sperm-Cervical MucusInteraction.4ed. Madrid. Medica Panamericana 2001. P. 35.
5.Biswas, S. Ferguson, K.M, Stendronska J, Baffoe G: Fructose Hormone Levels in semen: their Correlation with sperm counts & motility.Fertil Steril, 30:200 (1978).
Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Chauhan S,Suhalka ML,Kaur M. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Review article
Rajeswari S1 & Swaminathan S2,*
Affiliation:-
1Junior Technical Officer, Department of Biochemistry, Apollo Speciality Hospitals, Ayanambakkam, Chennai 600 095, India
2Senior Consultant and Head, Department of Biochemistry, Apollo Speciality Hospitals, Ayanambakkam, Chennai 600 095, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Biochemistry, Apollo Speciality Hospitals, Ayanambakkam, Chennai 600 095, India.
Address reprint requests to
Dr. S. Swaminathan.
Senior Consultant and Head,
Department of Biochemistry, Apollo Speciality Hospitals, No. 64, Vanagaram to Ambattur Main Road, Ayanambakkam, Chennai – 600 095, India
Article citation:
Rajeswari S, Swaminathan S. Role of thymus in infections – an update. J Pharm Biomed Sci. 2014; 04(10):918-925. Available at www.jpbms.info
ABSTRACT
Thymus is a specialised organ connected with several immune systems such as the development of T-Cells, induction of central tolerance, production and release of thymosin which aids in the development of disease fighting T-cells. The review article bringing out some research findings in the alteration of Thymus function due to various infections and some specific markers released into blood circulation, the measurement of which are used in clinical diagnosis involved in altered Thymus function due to infections. An update condensed summary from many recent findings has been presented in this article.
KEYWORDS: Thymosin; T-Cells; CD4(+); CD 8+; HIV; TNF-α.
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Source of support: None
Competing interest / Conflict of interest:
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Rajeswari S, Swaminathan S. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
Original article
Dilip. M. Rampure, M.D; V.R.B. Kumar Surapureddy*, M.B.B.S; G. Rajasekharappa
Affiliation:-
Department of General Medicine, Mamatha General Hospital, Giri Prasad Nagar,Khammam. 507001, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of General Medicine, Mamatha General Hospital, Giri Prasad Nagar, Khammam. 507001, India
Address reprint requests to
Dr.V.R.B. Kumar Surapureddy.
Department of General Medicine, Mamatha General Hospital, Giri Prasad Nagar, Khammam. 507001, India
Article citation:
Rampure DM, Surapureddy VRB.K, Rajasekharappa G. A Comparative evaluation of stroke in diabetics and non diabetics. J Pharm Biomed Sci. 2014;04(10):894-897. Available at www.jpbms.info
ABSTRACT
The World Health Organization (WHO) definition of stroke is: “rapidly developing clinical signs of focal (or global) disturbance of cerebral function, with symptoms lasting 24 hours or longer or leading to death, with no apparent cause other than of vascular origin”. Diabetes is an independent risk factor for stroke. It is associated with a 2- to 3-fold increase in the risk of stroke. Our study aims to study and compare the incidence, clinical presentation and outcome of stroke in diabetics and non diabetics. It is a prospective case control observational study conducted over a period of six months. 80 patients with stroke were included in the study (40 diabetics and 40 non diabetics). The study population was selected randomly. We found that the mean age of incidence in Diabetic stroke patients was 55±9.93 and in Non-Diabetic stroke patients was 58.92±13.26. The mean blood sugar on admission in diabetic group was 214.85 ± 76.0 compared with 132.28 ± 42.37 in non-diabetic group. Hemorrhagic strokes were more frequent in the non diabetics and ischemic strokes in the diabetic stroke groups. Diabetic stroke patients had a longer duration of hospital stay with 7.82± 4.65 days as compared to non diabetics with 5.92±4.80 days. We conclude that Stroke in diabetes differs from that of stroke in non-diabetics with respect to age, stroke type, stroke severity and outcome. Hyperglycemia at stroke onset is associated with higher risk of poor outcome.
KEYWORDS: Diabetes; Stroke.
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The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Rampure DM, Surapureddy VRB.K, Rajasekharappa G. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.