DocumentsDate added
Research article
Shenoy Poornima1, Hemavathi1,*, Sarmah Pooja1,¥,R Sharvani1,¥
Affiliation:-
1Professor, Department of Microbiology,1,* Professor & HOD, Department of Microbiology, 1,¥Assistant Professor, Department of Microbiology, Sapthagiri Institute of Medical Sciences & Research Centre, Bangalore-90,India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Microbiology, Sapthagiri Institute of Medical Sciences & Research Centre, Bangalore-90,India
Address reprint requests to
Dr Hemavathi,
Professor & HOD, Department of Microbiology, Sapthagiri Institute of Medical Sciences & Research Centre, Chikkasandra, Hesarghatta Main Road, Bangalore-560090,India
Article citation:
Poornima S, Hemavathi,Pooja S, Sharvani R. Current trend in transfusion transmitted infections among blood donors: a three year retrospective study. J Pharm Biomed Sci. 2014;04(10):914-919. Available at www.jpbms.info
ABSTRACT
Introduction: The problem of Transfusion Transmitted Infections is proportional to the prevalence of the infections in the blood donors, so it is mandatory to screen Hepatitis B and C, HIV, syphilis and malaria. As the focus of this year’s World Blood Donor Day campaign is "Safe blood for saving mothers”, a cross sectional retrospective study was undertaken to determine the sero-prevalence of the above diseases among the voluntary and replacement donors and to correlate the findings with age and sex.
Materials & Methods: Data was collected from the hospital blood bank records and was analyzed. A total of 8688 units of blood were tested for HIV (p24 antigen and HIV 1 & 2 antibodies by 4th generation ELISA), HBV and HCV (ELISA), syphilis by RPR test confirmed by TPHA and malaria by immunochromatographic test.
Results: Out of a total of 8688 units of blood tested, 6968 (80.20%) were from replacement & 1720 (19.20%) were from voluntary donors; with a preponderance of males (97.79%) to females (2.21%). Overall sero-prevalence was 0.37%, 0.94% and 0.37% for HIV, HBV and HCV respectively; 0.12% were reactive for syphilis. Two (0.02%) units showed dual infection with HIV and HCV. There was an increased prevalence of HIV, HBV, HCV and syphilis among replacement donors compared to the voluntary donors. None of the samples were positive for malaria.
Conclusions: Strict criteria for donor selection, health education coupled with sensitive screening tests are the possibilities of reducing Transfusion Transmitted Infections.
KEYWORDS: Age; Replacement donors; Sex; Transfusion transmitted infections; Voluntary donors.
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Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Poornima S,Hemavathi,Pooja S,Sharvani R. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.