DocumentsDate added
Original article
Kranthi Kumar G1,*, Tripura Lakshmi J2, Bindu Garg3, Ashish Goel3
Affiliation:-
1Demonstrator, 3Associate Professor, Department of Physiology, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, U.P., India
2Demonstrator, Department of Physiology, Rohilkhand Medical College & Hospital, Bareilly, U.P.,India
4Assistant Professor, Department of Physiology, Shri Dev Suman Subharti Medical College, Dehradun, UP.,India
The name of the department(s) and institution(s) to which the work should be attributed:
1.Department of Physiology, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, U.P., India
2.Department of Physiology, Rohilkhand Medical College & Hospital, Bareilly, U.P., India
3.Departmtent of Physiology, Shri Dev Suman Subharti Medical College, Dehradun, U.K., India
Address reprint requests to
Dr. Kranthi Kumar Garikapati.
Department of Physiology, SRMS IMS, Bareilly, U.P, India
Article citation: Garikapati KK, Lakshmi T, Garg B, Goel A. Study of mean cardiac axis of electrocardiogram on young Adults. J Pharm Biomed Sci. 2014; 04(10):887-893. Available at www.jpbms.info
ABSTRACT
Introduction: Obesity is a condition with excess of body fat in an individual. As per WHO data in 2005 there were about 400 million obese adults worldwide. Obesity is a most important predisposing factor for cardiovascular morbidity and mortality. Determination of mean cardiac axis (MCA) assisted in the diagnosis of early changes in the cardiovascular system. Obese people tend to have high resting heart rate, high blood pressure and leftward shift of the mean cardiac axis.
Aims: The present study was aimed to describe the impact of obesity on blood pressure and mean cardiac axis in healthy young adult individuals.
Materials and Methods: The study included 71 young adult individuals with age between 18-30 years. These were divided into 5 categories as per WHO classification of body mass index (BMI). Anthropometric parameters, pulse and blood pressure were recorded. MCA was determined from the standard bipolar limb lead electrocardiogram.
Statistical analysis: Using Microsoft Excel 10 data was analyzed. Values were depicted as mean ± SD & Pearson correlation was performed.
Results: It was noted that body surface area (BSA), waist circumference (WC), hip circumference (HC), systolic & diastolic blood pressure (SBP & DBP) increased with increment in BMI. It was also noted that MCA showed a leftward shift when normal BMI subjects were compared with obese subjects, though it was still within the normal range. BMI, BSA and WC had a significant negative correlation with mean cardiac axis.
Conclusion: Obesity based on BMI and WC adversely affects the blood pressure and mean cardiac axis.
KEYWORDS: Obesity; Mean cardiac axis; Electrocardiogram; Body mass index; Waist circumference.
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Source of support: None
Competing interest / Conflict of interest:
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Garikapati KK, Lakshmi T,Garg B, Goel A. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Dilip. M. Rampure, M.D; V.R.B. Kumar Surapureddy*, M.B.B.S; G. Rajasekharappa
Affiliation:-
Department of General Medicine, Mamatha General Hospital, Giri Prasad Nagar,Khammam. 507001, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of General Medicine, Mamatha General Hospital, Giri Prasad Nagar, Khammam. 507001, India
Address reprint requests to
Dr.V.R.B. Kumar Surapureddy.
Department of General Medicine, Mamatha General Hospital, Giri Prasad Nagar, Khammam. 507001, India
Article citation:
Rampure DM, Surapureddy VRB.K, Rajasekharappa G. A Comparative evaluation of stroke in diabetics and non diabetics. J Pharm Biomed Sci. 2014;04(10):894-897. Available at www.jpbms.info
ABSTRACT
The World Health Organization (WHO) definition of stroke is: “rapidly developing clinical signs of focal (or global) disturbance of cerebral function, with symptoms lasting 24 hours or longer or leading to death, with no apparent cause other than of vascular origin”. Diabetes is an independent risk factor for stroke. It is associated with a 2- to 3-fold increase in the risk of stroke. Our study aims to study and compare the incidence, clinical presentation and outcome of stroke in diabetics and non diabetics. It is a prospective case control observational study conducted over a period of six months. 80 patients with stroke were included in the study (40 diabetics and 40 non diabetics). The study population was selected randomly. We found that the mean age of incidence in Diabetic stroke patients was 55±9.93 and in Non-Diabetic stroke patients was 58.92±13.26. The mean blood sugar on admission in diabetic group was 214.85 ± 76.0 compared with 132.28 ± 42.37 in non-diabetic group. Hemorrhagic strokes were more frequent in the non diabetics and ischemic strokes in the diabetic stroke groups. Diabetic stroke patients had a longer duration of hospital stay with 7.82± 4.65 days as compared to non diabetics with 5.92±4.80 days. We conclude that Stroke in diabetes differs from that of stroke in non-diabetics with respect to age, stroke type, stroke severity and outcome. Hyperglycemia at stroke onset is associated with higher risk of poor outcome.
KEYWORDS: Diabetes; Stroke.
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Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Rampure DM, Surapureddy VRB.K, Rajasekharappa G. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Review article
Rajeswari S1 & Swaminathan S2,*
Affiliation:-
1Junior Technical Officer, Department of Biochemistry, Apollo Speciality Hospitals, Ayanambakkam, Chennai 600 095, India
2Senior Consultant and Head, Department of Biochemistry, Apollo Speciality Hospitals, Ayanambakkam, Chennai 600 095, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Biochemistry, Apollo Speciality Hospitals, Ayanambakkam, Chennai 600 095, India.
Address reprint requests to
Dr. S. Swaminathan.
Senior Consultant and Head,
Department of Biochemistry, Apollo Speciality Hospitals, No. 64, Vanagaram to Ambattur Main Road, Ayanambakkam, Chennai – 600 095, India
Article citation:
Rajeswari S, Swaminathan S. Role of thymus in infections – an update. J Pharm Biomed Sci. 2014; 04(10):918-925. Available at www.jpbms.info
ABSTRACT
Thymus is a specialised organ connected with several immune systems such as the development of T-Cells, induction of central tolerance, production and release of thymosin which aids in the development of disease fighting T-cells. The review article bringing out some research findings in the alteration of Thymus function due to various infections and some specific markers released into blood circulation, the measurement of which are used in clinical diagnosis involved in altered Thymus function due to infections. An update condensed summary from many recent findings has been presented in this article.
KEYWORDS: Thymosin; T-Cells; CD4(+); CD 8+; HIV; TNF-α.
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Source of support: None
Competing interest / Conflict of interest:
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Rajeswari S, Swaminathan S. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
Original article
Sangita Chauhan1,*, M. L. Suhalka1,¥, Manjinder Kaur1,£
Affiliation:-
1M.D. Student,1,¥HOD,1,£Professor,Department of Physiology, Geetanjali Medical College & Hospital, Udaipur (Raj.), India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Physiology, Geetanjali Medical College & Hospital, Udaipur (Raj.), India
Address reprint requests to
Dr. Sangita Chauhan
Department of Physiology, Geetanjali Medical College & Hospital, Udaipur (Raj.),India
Article citation:
Chauhan S, Suhalka ML, Kaur Ml. A study of relationship between seminal fructose & infertility in man. J Pharm Biomed Sci. 2014; 04(09):926-929. Available at www.jpbms.info
ABSTRACT
Background: Fructose is secreted by the seminal vesicles which is the main source of energy and is responsible for the motility of the sperms. Lower level of seminal fructose has been observed in hypofunction of the seminal vesicles and has been a cause related to infertility in males.
Objectives: To find out relationship between seminal fructose concentration and sperm counts. Semen of 120 men having no disturbances in the seminal vesicular function were investigated.
Material and Methods: Semen was collected from normozoospermic, oligozoospermic and azoospermic men. Collection of Seminal fluid and its analysis was done using the WHO standards.
Results: 120 subjects were studied, out of which 20 were azoospermic, 50 were oligozoospermic and 50 were normozoospermic. Their ages ranged from 25-55 years. Estimation of sperm count and semen Fructose levels was done. The range of seminal fructose was determined and was correlated with the sperm concentration by Pearson correlation .By this study it was concluded that there is a correlation between seminal fructose and sperm concentration.
Conclusion: Seminal fructose could be used as important marker in testing infertility cases.
KEYWORDS: Seminal Fructose; Infertility; Sperm Concentration.
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Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Chauhan S,Suhalka ML,Kaur M. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Review article
Deepak Viswanath1,*, Anindita Sarma2
Affiliation:
1*Professor and Head,2Postgraduate Student, Department of Pedodontics and Preventive Dentistry, Krishnadevaraya College of Dental Sciences, Int. Airport Road, Hunasamaranahalli, Bangalore, India-562 157
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Pedodontics and Preventive Dentistry, Krishnadevaraya College of Dental Sciences, Int. Airport Road, Hunasamaranahalli, Bangalore, India-562 157.
Address reprint requests to
Dr.Deepak Viswanath,
Department of Pedodontics and Preventive Dentistry, Krishnadevaraya College of Dental Sciences ,Int. Airport Road, Hunasamaranahalli, Bangalore, India- 562 157
Article citation: Viswanath D, Sarma A. Informed Consent in Pediatric Dentistry: Ethics and Pitfalls- A Review. J Pharm Biomed Sci. 2014;04(10):834-838. Available at www.jpbms.info
ABSTRACT
Informed consent is a leading topic of interest in health care field. This paper aims at all the pros and cons of informed consent in dentistry with special attention to the pediatric sector. The communication by medical and dental practitioners has to be legitimate as the patient’s right to know constitutes the basis of modern medical ethics. It is important for every dentist to know and learn about informed consent not only on medico-legal grounds but also to build trust with the patients.
KEYWORDS: Battery; Behaviour management; Bolam Test; Informed Consent; Pediatric informed consent.
Source of support: None
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Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Viswanath D, Sarma A. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.