DocumentsDate added
Case report
Cemil Kavalci1,*, Meliha Findik1, Elif Kilicli1, Gulsum Kavalci2, Polat Durukan3
Affiliation:-
1Baskent University Faculty of Medicine, Emergency Department, Ankara, Turkey
2Yenimalle State Hospital, Anesthesia Department, Ankara, Turkey
3Erciyes University Faculty of Medicine, Emergency Department, Kayseri, Turkey
The name of the department(s) and institution(s) to which the work should be attributed:
1.Baskent University Faculty of Medicine, Emergency Department, Ankara, Turkey
2.Yenimalle State Hospital, Anesthesia Department, Ankara, Turkey
3.Erciyes University Faculty of Medicine, Emergency Department, Kayseri, Turkey
Address reprint requests to
Cemil Kavalci,
Associate Professor,
Baskent University Faculty of Medicine, Emergency Department, 06370 Ankara, Turkey
Article citation: Kavalci C , Findik M, Kilicli E, Kavalci G, Durukan P. Intravesical foreign body: Silicone. J Pharm Biomed Sci. 2014; 04(11):941-942. Available at www.jpbms.info
ABSTRACT
Intravesical foreign bodies are rarely seen. Forty-two year old male patient was admitted to the emergency room with complaints of inability to urinate for one day. Tubular foreign body in the bladder was detected on ultrasonography. About 30 cm long and 20 French thick silicone foreign body was removed from the bladder by cystoscopy.
KEYWORDS: Emergency; bladder; foreign body.
REFERENCES
1. Bello JO, Badmus KO, Babata AL, Bello HS. Polyembolokoilamania: Self-insertion of transistor radio antenna in male urethra. Niger Med J. 2013;54:206-8. doi: 10.4103/0300-1652.114578.
2. Datta B, Ghosh M, Biswas S. Foreign Bodies in Urinary Bladders. Saudi J Kidney Dis Transpl 2011;22:302-5,
3. Fikri O, Ozkan A, Kurtuluş OF, Bahadır M, Balcı C, Hazar Aİ, Nuhoglu B. Foreign Body in Bladder of a Patient with Urethral Stenosis: A Case Report. JAREM 2012;2:82-84.
ACKNOWLEDGEMENT
This study presented on 1. İntercontinental Emergency Medicine Congress, 15-18 May 2014, Turkey.
Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © Kavalci C, Findik M, Kilicli E, Kavalci C, Durukan P. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
HG Hamza*, Z K Mohammed, A A Adullahi and T B Kingimi
Affiliation:-
Department of Biochemistry, Faculty Science University of Maiduguri, PMB 1069 Maiduguri, Nigeria
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Biochemistry, Faculty Science University of Maiduguri, PMB 1069 Maiduguri, Nigeria
Address reprint requests to
Dr.HG Hamza
Department of Biochemistry, Faculty Science University of Maiduguri, PMB 1069 Maiduguri, Nigeria
Article citation:
Hamza HG, Mohammed ZK, Adullahi AA, Kingimi TB. Antioxidant potentials of crude extracts of Gueirra sengalensis Leaves on CCL4 induced oxidative stress in Albino rat. J Pharm Biomed Sci. 2014; 04(11):941-945. Available at www.jpbms.info
ABSTRACT
Background: There is increasing recognition that many of today’s diseases are due to the “oxidative stress” that results from an imbalance between the formation and neutralization of reactive molecules such as reactive oxygen species(ROS) and reactive nitrogen species (RNS).
Aim: The main objective of the present study was to evaluate the antioxidant activity of Gueirra senegalensis leaves, a plant which is routinely used in ethonomedicinal practice for the treatment and management of most common ailments in this part of the world.
Methods: The anti oxidative effect of extracts of Guierra senegalensis (500mg per kgbodyweight) on carbon tetrachloride induce oxidative stress in rats was tested using spectrophotometric method to measure rate of decomposition of H2O2 and estimation of thiobarbituric acid reducing substance. The extracts effects were compared with standard drug (Silymarin 140mg per kg body weight).
Results: CCl4 intoxication induced a marked increase in TBARS level (P<0.05) and a significant reduction of catalase activity (P<0.05), the extract at the dose of 500mg per kg body weight significantly (P<0.05) ameliorated the deviation caused by CCl4 induced oxidative stress.
Conclusion: The results of the present study indicate that the aqueous and ethanolic extracts of G. senegalensis showed protective abilities against CCl4 induced oxidative stress in rats.
KEYWORDS: Antioxidant; Gueirra senegalensis; Oxidative stress.
REFERENCES
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13.Nwafor, P. A and HG Hamza.. Antidiarrhoeal and Anti-Inflammatory Effects of Methanolic Extract of Guiera senegalensis Leaves in Rodents. Journal of Natural Remedies,(2007);7(1):72-79
14.Shettima, A Y, Karumi Y, Tijjani M.A and Sodipo OA Phytochemical and antidiarrhoel properties of ethyl acetate root extract of Guierra senegalensis JF Gmel via oral route. J. Chem.Pharm.Res. 2012;4(10):4604-46-12.
15.Silva, O., and Gomes, E.T, Guieranone A, a Naphthyl Butenone from the Leaves of Guiera senegalensis with antifungal Activity. J. Nat. Prod.2003; 66(3):447–449.
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Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Hamza HG, Mohammed ZK, Adullahi AA, Kingimi TB. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Case report
Madhuri J Patil*
Affiliation:-
1Assistant Professor, Department of Obstetrics and Gynecology ,Vasantrao Naik Government Medical College,Yavatmal, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Obstetrics and Gynecology ,Vasantrao Naik Government Medical College,Yavatmal, India
Address reprint requests to
Dr.Madhuri J Patil.
Assistant Professor, Department of Obstetrics and Gynecology, Vasantrao Naik Government Medical College, Yavatmal, India
Article citation:
Patil MJ. Acute presentation of heterotopic pregnancy with tubal rupture following spontaneous conception. J Pharm Biomed Sci. 2014; 04(11):1007-1010. Available at www.jpbms.info
ABSTRACT
Background: Heterotopic pregnancy carries a significantly higher maternal mortality and morbidity due to rupture of ectopic gestation. Hence, early diagnosis and management is crucial. Incidence in the general population is increased due to increased incidence of pelvic inflammatory diseases. The five common clinical signs of heterotopic pregnancy are abdominal pain, adnexal mass, signs of peritoneal irritation, hypovolumic shock, and uterine fundus larger than menstrual date. Therefore, for early diagnosis of Heterotopic pregnancy a holistic approach and thorough pelvic ultrasound is crucial to reduce mortality and morbidity in such cases.
KEYWORDS: Heterotopic pregnancy; intrauterine; laparotomy ultrasound.
REFERENCES
1.Sumeet N Baheti, K Jayakrishanan. Heterotopic pregnancy in a natural conception: International journal of infertility and fetal medicine 2010;1:41-43.
2.Derek A, Beyer M, Daniel A, Domesic M D. Heterotopic pregnancy in emergency diagnostic challenge.OBG Management 2002;14:10.
3.Tng Chang Kwok, George Morgan. Think heterotopic: A case report of heterotopic Pregnancy detected on through ultrasonography. Journal of medical cases 2012;3(5):326-28.
4.Govindarajan M J, Rajan B. Heterotopic pregnancy in natural conception. Journal of human reproductive science 2008;(1);37-38.
5.Karim Ibn Majdoub Hassani, Abderrahim El Bouazzaoui, Mohammod O Khatouf, and Khalid Mazaz. Heterotopic pregnancy a diagnosis we should suspect more often. Journal of emergencies, trauma and shock 2010;3(3):304.
6.Sameer Umranikar, Aarti Umranikar, Junaid Rafi, et al. Acute presentation of a heterotopic pregnancy following spontaneous conception: case report. Cases journal 2009,2.9369. doi:10.1186/1757-1626-2-9369:1-4.
7.Barrenetxea G, Barinaga Rementeria L, Lopez de Larruzea A, Agirregoikoa J A, Mandiola M, Carbonero K. Heterotopic pregnancy: two cases and a comparative review. Fertil Steril 2007;87(2):417 e419-415.
8.Bignardi T, Alhamdan D, Condous G. Is ultrasound the new gold standard for the diagnosis of ectopic pregnancy. Semin Ultrasound CT MR 2008;29(2):114-20.
9.Sue Yazaki Sun, Edward Araujo junior, Julio Elito junior, Liliam Cristine Rolo. Diagnosis of heterotopic pregnancy using ultrasound and MRI in the first trimester pregnancy: A case Report. Case Reports in Radiology 2012;Article ID 317592:1-3.
Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript
Copyright © 2014 Patil MJ. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article
Wisam R. Hassan1,*,Haydar F. AL-Tukmagi1,Osamah T. Muslim2
Affiliation:-
1Department of Clinical Pharmacy, College of Pharmacy, University of Baghdad, Baghdad, Iraq
2Department of Gastroenterology and Hepatology ,AL-Diwaniya Teaching Hospital, College of Medicine, University of AL-Qadisyia, AL-Qadisyia, Iraq
The name of the department(s) and institution(s) to which the work should be attributed:
1.Department of Clinical Pharmacy, College of Pharmacy, University of Baghdad, Baghdad, Iraq
2.Department of Gastroenterology and Hepatology,AL-Diwaniya Teaching Hospital, College of Medicine, University of AL-Qadisyia, AL-Qadisyia, Iraq
Address reprint requests to
Wisam R. Hassan.
Department of Clinical Pharmacy, College of Pharmacy, University of Baghdad, Baghdad, Iraq
Article citation:
Hassan WR, Al-Tukmagi HF, Muslim OT. Efficacy of a 10 Days course of levofloxacin based therapy after Failure of sequential therapy for Helicobacter pylori infection in Iraqi Patients. J Pharm Biomed Sci. 2014; 04(11):1031-1038. Available at www.jpbms.info
ABSTRACT
Helicobacter pylori (H. Pylori) is one of the most important risk factors of Peptic ulcer disease (PUD) and gastric cancer. The success rate of triple therapy (TT) has been declined during the last decade , sequential therapy (ST)has been proposed as an alternative to the TT regimen. A 10 days levofloxacin-based therapy(LBT) constitutes an encouraging second-line strategy after failure of ST.
The aim of this study was to establish the efficacy and tolerability of LBT after failure of (ST), also measuring the cumulative eradication rate of both regimens.
A prospective, open-label randomized clinical trial on 86 patients who had active H. Pylori infection with various gastrointestinal symptoms. The second line LBT was given after failure of the first line ST, bacterial eradication was examined 4-8weeks after treatment by using a fecal antigen test (FAT). The result was 20 patients after ST failure, only 19 patients enrolled to take LBT. The eradication rate(ER) of per-protocol and intention-to-treat for second line was 84.21% (16/19, 95% C.I 68%-100.1%) for both genders without significant difference (p=0.76) between males and females, cumulative eradication rates were 94.86% and 95.95% for both intention-to-treat and per-protocol, respectively. Compliance to the second line was 100% and adverse effects were mostly mild (36.84%) to moderate (10.56%), with little sever (5.26%) that had no effect on completion of treatment. It is concluded that a 10 days levofloxacin based therapy constitutes an encouraging second line regimen after failure of sequential therapy, with a high compliance and low adverse effects and yield a high cumulative eradication rate in clinical practice.
KEYWORDS: H. Pylori; levofloxacin; sequential therapy.
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6.Costa AC, Figueiredo C, and Touati E. pathogenesis of Helicobacter pylori infection. Helicobacter 2009;14(suppl 1):15-20.
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35. Zullo A., de Francesco V., Manes G., Scaccianoce G., Cristofari F., and Hassan C., “Second-line and rescue therapies for Helicobacter pylori eradication in clinical practice,” Journal of Gastrointestinal and Liver Diseases, 2010;19(2):131–134.
36.Gisbert J, Marcos S, Moreno-Otero R, Pajares J. Third-line rescue therapy with levofloxacin is more effective than rifabutin rescue regimen after two Helicobacter pylori treatment failures. Aliment Pharmacol Ther. 2006;24:1469-74.
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Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript
Copyright © 2014 Hassan WR, Al-Tukmagi HF, Muslim OT. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article
Surinder Kumar1, Baljinder Singh2,*, Varsha A singh3, Ovais Karnain Wadoo4, Yogesh5
Affiliation:-
1Associate Professor, Department of Microbiology, BPS GMC for women Khanpur Kalan, Sonepat, Haryana, India 2Associate Professor, Department Physiology, M.M. Institute of Medical Sciences and Research, Mullana, Ambala, Haryana, India
3Professor, Department of Microbiology, M.M.Institute of Medical Sciences and Research, Mullana, Ambala, India
4Resident, Department of Physiology, M.M. Institute of Medical Sciences and Research, Mullana, Ambala, Haryana, India
5Demonstrator,Department Of Physiology, BPS GMC for women Khanpur Kalan, Sonepat, Haryana, India
The name of the department(s) and institution(s) to which the work should be attributed:
1.Department of Microbiology, BPS GMC for women Khanpur Kalan, Sonepat, Haryana, India
2.Department Physiology,M.M. Institute of Medical Sciences and Research, Mullana, Ambala, Haryana, India
3.Department Of Physiology, BPS GMC for women Khanpur Kalan, Sonepat, Haryana, India
Address reprint requests to
Dr Baljinder Singh.
Department Physiology, M.M.Institute of Medical Sciences and Research, Mullana, Ambala, Haryana, India - 133207
Article citation:
Kumar S, Singh B, Singh VA, Wadoo OK, Yogesh. Prevalence of Giardia lamblia in patients with gastrointestinal symptoms in rural tertiary care hospital in Haryana. J Pharm Biomed Sci. 2014;04(11):946-949. Available at www.jpbms.info
ABSTRACT
An intestinal parasitic infestation is a major public health problem. Prospective study was carried out to know the prevalence of Giardia lamblia in patients of gastrointestinal symptoms at MM Institute of Medical Sciences and Research Mullana, Ambala. A total of 656 stool samples of HIV negative patients with gastrointestinal symptoms from OPD and wards were included in this study. Samples were examined for parasites by saline wet mount, Iodine mount and after concentration. Out of 656 stool specimens Giardia lamblia isolated in 6.7% cases. The Giardia lamblia was more prevalent in younger age group with statistically significant in < 15 years of age (p<0.05). Prevalence was also more in males as compared to females but it was not statistically significant (p>0.05). The seasonal variation of Giardia was also seen with more prevalence in hot and moist season being water borne disease .Hence; there is need of awareness among the people for taking safe drinking water.
KEYWORDS: Giardia; Gastrointestinal; water borne disease
Source of support: None
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Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Kumar S, Singh B, Singh VA, Wadoo OK, Yogesh. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.