DocumentsDate added
Original article
HG Hamza*, Z K Mohammed, A A Adullahi and T B Kingimi
Affiliation:-
Department of Biochemistry, Faculty Science University of Maiduguri, PMB 1069 Maiduguri, Nigeria
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Biochemistry, Faculty Science University of Maiduguri, PMB 1069 Maiduguri, Nigeria
Address reprint requests to
Dr.HG Hamza
Department of Biochemistry, Faculty Science University of Maiduguri, PMB 1069 Maiduguri, Nigeria
Article citation:
Hamza HG, Mohammed ZK, Adullahi AA, Kingimi TB. Antioxidant potentials of crude extracts of Gueirra sengalensis Leaves on CCL4 induced oxidative stress in Albino rat. J Pharm Biomed Sci. 2014; 04(11):941-945. Available at www.jpbms.info
ABSTRACT
Background: There is increasing recognition that many of today’s diseases are due to the “oxidative stress” that results from an imbalance between the formation and neutralization of reactive molecules such as reactive oxygen species(ROS) and reactive nitrogen species (RNS).
Aim: The main objective of the present study was to evaluate the antioxidant activity of Gueirra senegalensis leaves, a plant which is routinely used in ethonomedicinal practice for the treatment and management of most common ailments in this part of the world.
Methods: The anti oxidative effect of extracts of Guierra senegalensis (500mg per kgbodyweight) on carbon tetrachloride induce oxidative stress in rats was tested using spectrophotometric method to measure rate of decomposition of H2O2 and estimation of thiobarbituric acid reducing substance. The extracts effects were compared with standard drug (Silymarin 140mg per kg body weight).
Results: CCl4 intoxication induced a marked increase in TBARS level (P<0.05) and a significant reduction of catalase activity (P<0.05), the extract at the dose of 500mg per kg body weight significantly (P<0.05) ameliorated the deviation caused by CCl4 induced oxidative stress.
Conclusion: The results of the present study indicate that the aqueous and ethanolic extracts of G. senegalensis showed protective abilities against CCl4 induced oxidative stress in rats.
KEYWORDS: Antioxidant; Gueirra senegalensis; Oxidative stress.
REFERENCES
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Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2014 Hamza HG, Mohammed ZK, Adullahi AA, Kingimi TB. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Case report
Cemil Kavalci1,*, Meliha Findik1, Elif Kilicli1, Gulsum Kavalci2, Polat Durukan3
Affiliation:-
1Baskent University Faculty of Medicine, Emergency Department, Ankara, Turkey
2Yenimalle State Hospital, Anesthesia Department, Ankara, Turkey
3Erciyes University Faculty of Medicine, Emergency Department, Kayseri, Turkey
The name of the department(s) and institution(s) to which the work should be attributed:
1.Baskent University Faculty of Medicine, Emergency Department, Ankara, Turkey
2.Yenimalle State Hospital, Anesthesia Department, Ankara, Turkey
3.Erciyes University Faculty of Medicine, Emergency Department, Kayseri, Turkey
Address reprint requests to
Cemil Kavalci,
Associate Professor,
Baskent University Faculty of Medicine, Emergency Department, 06370 Ankara, Turkey
Article citation: Kavalci C , Findik M, Kilicli E, Kavalci G, Durukan P. Intravesical foreign body: Silicone. J Pharm Biomed Sci. 2014; 04(11):941-942. Available at www.jpbms.info
ABSTRACT
Intravesical foreign bodies are rarely seen. Forty-two year old male patient was admitted to the emergency room with complaints of inability to urinate for one day. Tubular foreign body in the bladder was detected on ultrasonography. About 30 cm long and 20 French thick silicone foreign body was removed from the bladder by cystoscopy.
KEYWORDS: Emergency; bladder; foreign body.
REFERENCES
1. Bello JO, Badmus KO, Babata AL, Bello HS. Polyembolokoilamania: Self-insertion of transistor radio antenna in male urethra. Niger Med J. 2013;54:206-8. doi: 10.4103/0300-1652.114578.
2. Datta B, Ghosh M, Biswas S. Foreign Bodies in Urinary Bladders. Saudi J Kidney Dis Transpl 2011;22:302-5,
3. Fikri O, Ozkan A, Kurtuluş OF, Bahadır M, Balcı C, Hazar Aİ, Nuhoglu B. Foreign Body in Bladder of a Patient with Urethral Stenosis: A Case Report. JAREM 2012;2:82-84.
ACKNOWLEDGEMENT
This study presented on 1. İntercontinental Emergency Medicine Congress, 15-18 May 2014, Turkey.
Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © Kavalci C, Findik M, Kilicli E, Kavalci C, Durukan P. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.