DocumentsDate added
Review article
Sharma R C, Badyal Ashima*
Affiliation:-
Department of Gynecology and Obstetrics, CMC Pathankot, Punjab, India
*Department of Biochemistry, GMC, Jammu, J&K, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Gynecology and Obstetrics, CMC Pathankot, Punjab, India
*Department of Biochemistry, GMC, Jammu, J&K, India
Address reprint requests to
Dr Ashima Badyal.
Department of Biochemistry, GMC, Jammu, J&K, India or at badyal.ashima@gmail.com
Article citation:
Sharma RC, Badyal A. NDVH: An alternative approach of hysterectomy. J Pharm Biomed Sci. 2015; 05(01):50-52. Available at www.jpbms.info
ABSTRACT:
The specialty of gynecology and obstetrics, in association with biochemical evaluations, exclusively caters to specific health need of the women in medical science. The reproductive system of women also follows a unique biological rhythm and undergoes specific changes with different cycles of reproduction anatomically, physiologically and biochemically. These phases are associated with different reference values of female sex hormones which should be timely ruled out. Research studies, world over, have worked in wide range of areas, including psychological and biochemical aspects of different reproductive phases, like pregnancy, menopause, contraception, infertility and surgical loss of uterus and breast, each being associated with different kind of stress. Evaluation of such problems, which turn into various complications like fibroid, pelvic inflammatory disease, etc, due to hormonal imbalance, so common in females, and specific to the cases where uterus is no longer required, sometimes generally leads to the decision of hysterectomy. Hysterectomy, abdominal or nondesent vaginal or subtotal laparoscopy assisted vaginal hysterectomy is by far the most frequently performed elective major operation in gynaecology. Non Descended Vaginal Hysterectomy must be practiced in all such cases where there is an indication for hysterectomy, because of fewer postoperative complications and almost no stress of major surgery. No abdominal incision is involved, and hence, cosmetically approved by patients, which allow recovery and return to work. There is an ample opportunity to learn and master vaginal delivery hence, thereby it is in the best interest of the patient if vaginal route is mastered and preferred. In order to maximize the proportion of hysterectomies performed vaginally, gynecologist need to be familiar with surgical techniques for dealing with non-descended uterus.
KEYWORDS: Hysterectomy, mental health, reproductive phases, Non Descended Vaginal Hysterectomy (NDVH).
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Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2015. Sharma RC, Badyal A. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Monika Srivastava1,*, Vandana Sharma2, Asha Dixit3, Abhijeet Yadav4,Deepak Sharma5, Dhiraj Kumar Srivastava6
Affiliation:-
1-5Department of Anatomy, Gandhi Medical College, Bhopal (MP), India
6Department of Community Medicine, UP Rural Institute of Medical Sciences & Research, Saifai, U.P, India
The name of the department(s) and institution(s) to which the work should be attributed:
1.Department of Anatomy, Gandhi Medical College, Bhopal (MP),India
2.Department of Community Medicine, UP Rural Institute of Medical Sciences & Research, Saifai, U.P, India
Address reprint requests to
Dr. Monika Srivastava.
C/o Mr. R.K Srivastava
H.no 1532, Near Ebnezer School, Bhagat Singh Nagar, Bhind Road, Gola Ka Mandir, Gwalior (MP)-474005
Article citation:
Srivastava M, Sharma V, Dixit A, Yadav A, Sharma D, Srivastava DK. Morphological analysis of myocardial bridges in formalin fixed hearts. J Pharm Biomed Sci.2015;05(01):01-05.Available at www.jpbms.info
ABSTRACT
Background: The fibers overlying the intramyocardial segment of an epicardial coronary artery are then termed as myocardial bridges. Although myocardial bridges may protect the covered arterial segment, in man there is a significant increase in the incidence of atherosclerosis in the vessel segment proximal to the myocardial bridges
Objectives: 1.Incidence of myocardial bridges. 2. Morphological distribution of myocardial bridges over the various branches of coronary arteries.
Material and Method: The present study was a Dissection (Hospital) based Cross sectional Descriptive study.. A total 60 hearts were dissected. The hearts were cleaned and numbered. They were dissected and Coronary Vessels were then traced from the aortic sinus to their termination by cleaning the epicardium and perivascular fat tissues by using different type’s forceps and scalpel. The origins and courses of two coronary arteries were thus cleared, colored and all the measurements were taken with the help of thread and ruler. Result: Out of total 60 hearts, 22 hearts showed the presence of myocardial bridges (36.7%). A higher incidence of myocardial bridges was noted in the left coronary artery as compared to right coronary artery. In the left coronary artery maximum incidence was noted in the anterior interventricluar artery followed the posterior interventricular branch.
Conclusion:The present study concludes that myocardial bridges are common in human hearts. They are more common in the left coronary artery and its branches. An anterior Interventricular branch of left coronary artery is most commonly affected.
KEYWORDS: Myocardial Bridges; Coronary arteries; Left Coronary artery.
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Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript
Copyright © 2015. Srivastava M, Sharma V, Dixit A, Yadav A, Sharma D, Srivastava DK. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
Research article
Smitha Nayak1, K.V.M.Varambally 2,Vinod C.Nayak3,Shankar B3,¥
Affiliation:-
1Associate Professor, 2Director, 3Associate Professor, School of Management, Manipal University Manipal, India
3,¥Associate Professor, Kasturba Medical College, Manipal University, India
The name of the department(s) and institution(s) to which the work should be attributed:
1. School of Management, Manipal University Manipal, India
2. Kasturba Medical College, Manipal University, India
Address reprint requests to
Dr.Smitha Nayak
Associate Professor, School of Management, Manipal University Manipal, India or at smithanayak.v@manipal.edu
Article citation:
Nayak S, Varambally KVM, Nayak VC, Shankar B. Impact of mass media on healthcare seeking behavior. J Pharm Biomed Sci. 2015;05(01):44-49. Available at www.jpbms.info
ABSTRACT:
The objective of the study is to obtain insights into the impact of mass media (television, news -paper, radio) on health seeking behavior among women with specific reference to Antenatal Care (ANC). ANC service, the dependent variable, is a dichotomous variable, defined as if the woman has received ANC from a trained healthcare professional (doctor, lady health visitor, auxiliary nurse midwife, nurse) at least once during the last pregnancy.
Results: Among 600 respondents of the study, around 61per cent (369 respondents) utilized ANC service form a trained healthcare professional at least once during their previous pregnancy and extent of ANC service. The extent of ANC service utilization was ‘low’ (29 per cent), ‘moderate’ (43 per cent) and ‘high’ (28 per cent) among the 369 respondents who had accessed ANC service. Socio Demographic factors had a significant association to ANC service utilization. Correlation analysis revealed that media exposure (r=0.65 ***) has a significant positive correlation to ANC service utilization. Logistic regression analysis revealed that media exposure had a significant influence of ANC service utilization (β=.43, t (364) =12.6, p<0.01). .
KEYWORDS: Mass media; Antenatal care; Health seeking behavior.
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Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Copyright © 2015. Nayak S, Nayak VC, Varambally KVM, Shankar B. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Fu Wen-Juan1, Chen Ju2, Ke Jian1, Yu Wen-Hui1, Wang Lan-Ying2, Wu Ding-Tao2,
Xiong Ai-Hua1, Nie Hong1* and Zhao Jing2*
Affiliation:
1Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University, Guangzhou 510632, China
2State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China
The name of the department(s) and institution(s) to which the work should be attributed:
1.Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University, Guangzhou 510632, China
2.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China
Address reprint requests to
Nie Hong/Zhao Jing
Tel: 86-20-85222810
Fax: 86-20-85224476
Article citation:
Fu Wen-Juan, Chen Ju, Ke Jian, Yu Wen-Hui, Wang Lan-Ying, Wu Ding-Tao, et al. Gastroprotective activity of Hericium erinaceus on gastric injury rat model induced by glacial acetic acid and pyloric ligation. J Pharm Biomed Sci.2015;05(01):72-79. Available at www.jpbms.info
ABSTRACT: This study investigated the effects of Hericium erinaceus extracts against gastric ulcer by glacial acetic acid combining pyloric ligation acute gastric ulcer rat model. Rats were randomly assigned to 9 groups including control, model, cimetidine (0.04 g.kg-1.d-1), HTG-2-S (2.0 g.kg-1.d-1), HTG-2-S (0.5 g.kg-1.d-1), HTG-2-S (0.125 g.kg-1.d-1), HTG-2-P (2.0 g.kg-1.d-1), HTG-2-P (0.5 g.kg-1.d-1) and HTG-2-P (0.125 g.kg-1.d-1). The drugs were given intragastrically once daily for 14 consecutive days. At the end of experiment, 2mL of 14.5 mmol/L glacial acetic acid was administered intragastrically, and pylorus was ligated with 3% pentobarbital sodium anesthesia to establish acute gastric ulcer rat models. Variables including gastric acidity, area of gastric ulcer, gastric H&E staining and activities of pepsin, trypsin, and lipase were investigated. The results showed that HTG-2-P (2 g.kg-1.d-1), HTG-2-P (0.125 g.kg-1.d-1) and HTG-2-S (0.5 g.kg-1.d-1) could raise the pH of gastric acid back to normal (p < 0.01 or p < 0.05). Compared with the model group, HTG-2-S (2 g.kg-1.d-1), HTG-2-S (0.5 g.kg-1.d-1), HTG-2-P (2 g.kg-1.d-1), HTG-2-P (0.5 g.kg-1.d-1), and HTG-2-P (0.125g.kg-1.d-1) could significantly reduce the gastric ulcer area and lower the activity of pepsin (p < 0.01 or p < 0.05). All dose groups of HTG-2-S and HTG-2-P were able to alleviate inflammatory cell infiltration in gastric mucous and submucous layers of rats. Therefore, we confirmed that extracts of Hericium erinaceus possessed remarkably protective effects against acute gastric ulcer in rats.
KEYWORDS: Hericium erinaceus; acute gastric ulcer; pyloric ligation; glacial acetic acid; pepsin; gastric acidity.
Statement of Originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
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Abbreviations: A, Control; B, Model; C, Cimetidine (0.04 g.kg -1.d-1); D, HTG-2-S (2.0 g.kg -1.d-1); E, HTG-2-S (0.5 g.kg -1.d-1); F, HTG-2-S (0.125 g.kg -1.d-1); G, HTG-2-P (2.0 g.kg -1.d-1); H, HTG-2-P (0.5 g.kg -1.d-1); I, HTG-2-P (0.125 g.kg -1.d-1).
Source of support: None
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Copyright © 2015. Fu Wen-Juan, Chen Ju, Ke Jian, Yu Wen-Hui, Wang Lan-Ying, Wu Ding-Tao, et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Mangal S Pawar*, YS Tawar
Affiliation:-
Department of Pharmaceutics, Bhupal Nobles, College of Pharmacy, Udaipur, Rajasthan, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Pharmaceutics, Bhupal Nobles, College of Pharmacy, Udaipur, Rajasthan, India
Address reprint requests to
Mangal S Pawar.
Department of Pharmaceutics, Bhupal Nobles, College of Pharmacy, Udaipur, Rajasthan,India
Article citation:
Panwar MS,Tanwar YS. Evaluation of stability of diltiazem hydrochloride floating microspheres at normal and accelerated conditions. J Pharm Biomed Sci.2015;05(01):57-60.Available at www.jpbms.info
ABSTRACT
The floating microspheres formulation containing diltiazem hydrochloride was prepared by non aqueous solvent evaporation method. With the recent trend towards globalization of manufacturing operation, it is imperative that the final product be sufficiently rugged for marketing worldwide under various climatic conditions including tropical, sub tropical and temperate. Stability studies were carried out as per ICH guidelines. The floating microspheres were placed in a screw capped glass containers and stored at room temperature, (25 ± 2°C) and humidity chamber (40°C, 75 % RH) for a period of 90 days. The product was evaluated for appearance every 10 days. Drug polymer compatibility and drug release studies were conducted as per the planned scheduled.
KEYWORDS: Diltiazem hydrochloride, Floating microspheres, Stability studies.
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Source of support: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript
Copyright © 2015. Panwar MS, Tanwar YS. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.