DocumentsDate added
Original article
Sushma Katkuri1,*,Shaheda Begum2
Affiliation:
1Assistant Professor, Department of Community Medicine, Malla Reddy Institute of Medical Sciences, Hyderabad, India
2Medical Intern, Deccan College of Medical Sciences, Hyderabad, India
The name of the department(s) and institution(s) to which the work should be attributed:
1. Department of Community Medicine, Malla Reddy Institute of Medical Sciences, Hyderabad, India
2.Deccan College of Medical Sciences, Hyderabad, India
Address reprint requests to
Dr Sushma Katkuri.
House No-9 Bhavya Shri Krishna Avenue,
Pragathi Nagar, Quthbulapur Mandal, Hyderabad-500090, India
Article citation:
Katkuri S,Begum S. Occupational exposure to blood and body fluids among health care workers in teaching hospital, Hyderabad, India. J Pharm Biomed Sci.2015;05(02):95-99. Available at www.jpbms.info
ABSTRACT:
Occupational Exposure to blood and body fluids among health care workers in teaching hospital in Hyderabad
Background: Needle stick injury means penetrating stab wound, introducing blood or other potentially hazardous material into the body of healthcare worker, during the performance of their duties, by a hollow bore needle or sharp instruments, including, needles, lancets, scalpels, and contaminated broken glass. According to the WHO, out of 35 million health workers worldwide, about 3 million receive percutaneous exposures to blood borne pathogens each year; two million of those to HBV, 0.9 million to HCV and 170 000 to HIV. Aims & Objectives: To determine the incidence of occupational exposures to blood and body fluids.
Materials & Methods: A cross-sectional study was conducted at Owaisi and Princess Esra Hospital, a Tertiary level, teaching hospital of Deccan College of Medical Sciences, Hyderabad, Andhra Pradesh, India. The study was done over a period of two months from April 2013-May 2013 with a sample of 150 health workers.
Results: Majority of the subjects were doctors contributing to 58.6% in which 33.3% were surgeons and 25.3% were non-surgeons were as 21% were nurses, 10% lab technicians, 7% operation theater assistants and 4% vaccinators. Out of 150 subjects 56% had needle stick injury in the past was as 44% didn’t have injury. The vaccination status about hepatitis B was good nearly 3/4th was vaccinated with hepatitis B & 1/4th were non-vaccinated.
Conclusion: A infection control committee should be formed in each and every health institute where medical staff can report their injuries and can get adequate counseling and guidance from them in handling the sharps.
KEYWORDS: Needle sticks injury; health care workers; blood borne.
Statement of Originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the
manuscript represents honest and original work.
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12.Lulie Walle, Emebet Abebe, Medihanit Tsegaye, Hanna Franco, Dereje Birhanu, Muluken Azage. Factors associated with needle stick and sharp injuries, among healthcare workers in Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia: facility based cross-sectional survey. Int J Infect Control 2013;9(4):1-9.
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Source of funding: None
Competing interest / Conflict of interest
The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Copyright © 2015. Katkuri S, Begum S. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Hitesh R Ahir1,* Parimal H Patel1,†, Alka B Nerurkar1,¥
Affiliation:
1,*Tutor, 1,†Assistant Professor, 1,¥Professor and Head of Department, Department of Microbiology, GMERS, Medical College, Valsad, Gujarat, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Microbiology, GMERS, Medical College, Valsad, Gujarat, India
Address reprint requests to
Hitesh R Ahir*
Department of Microbiology, GMERS, Medical College, Valsad, Gujarat, India
Article citation: Ahir HR, Patel PH, Nerurkar AB. Intestinal Parasitic Infections in Patients attending Tertiary Care Hospital, Valsad, south Gujarat, India: A retrospective study. J Pharm Biomed Sci. 2015; 05(02):117-121. Available at www.jpbms.info
ABSTRACT:
Intestinal parasitic infections are widely prevalent in developing countries due to poor sanitation and inadequate personal hygiene. They are responsible for considerable morbidity and mortality.
Aim: The study was undertaken to assess the prevalence of Intestinal Parasitic Pathogens amongst patients attending a tertiary care hospital in district valsad, Gujarat.
Materials and Methods: Stool samples from 291 patients which included 120 females and 171 males were collected and screened using conventional saline and iodine wet mount and examined by direct microscopy.
Results: In our study the prevalence of intestinal parasitic infection was found to be 13.40%. E.histolytica (45.23%) and A. duodenale ( 26.19%) were the commonest parasites isolated, followed by A lumbricoides (11.90%), S stercoralis (11.90%) and Hymenolepis nana (4.76%). Infection rate was highest in females (15 %) than males (12.28%).The infestation was higher in the 21-30 years age group as compared to others. Multiple parasitic infection are detected in three stool samples(7%).
Conclusion: Helminthic infections are more common than protozoal. The present study reports that intestinal parasitic infection is prevalent in this area and this study also indicate the usefulness and easy to perform stool examination at very low cost.
KEYWORDS: Intestinal parasitic infections.
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23.Baragundi MC, Sonth SB, Solahannwar S, Patil CS. The prevalence of parasitic infection in patients attending tertiary care hospital. Nat J Bas Med Sci. 2011; 2(1):31-4.
Source of funding: None
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Statement of Originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Copyright © 2015 Ahir HR, Patel PH, Nerurkar AB. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Guo Chen1, Zhenghua Ni2, Qingge Chen1, Xiongbiao Wang1,*
Affiliation:
1Department of Respiratory Medicine, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200062, PR China
2Central lab, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200062, PR China
The name of the department(s) and institution(s) to which the work should be attributed:
1. Department of Respiratory Medicine, Putuo Hospital, Shanghai University of Traditional Chinese Medicine &
2. Central lab, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200062, China
Address reprint requests to
Xiongbiao Wang.
Central lab, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200062,PR China
Article citation:
Wang et al. Gene silencing of IL-13 by siRNA aerosol inhalation inhibits asthma phenotype in the murine model of asthma. J Pharm Biomed Sci. 2015; 05(02):126-130. Available at www.jpbms.info
ABSTRACT:
Background: interleukin-13 has been shown to be a critical mediator of the asthma phenotype. It was reported that intravenously administration of the IL-13 siRNA in vivo reduced airway resistance significantly in the murine asthma model.
Objectives: This study was intended to investigate whether aerosol inhalation of IL-13 siRNA was effective in reduce IL-13 expression and thus attenuated asthma phenotype.
Methods: The ovalbumin (OVA)-challenged mouse model of asthma was used to assess the effect of IL-13 interference. Airway inflammation in lung tissue was assessed using hematoxylin and eosin (H&E). The mRNA expression of IL-13 gene was determined using real-time PCR.
Results: Aerosol inhalation of the IL-13 siRNA was shown to reduce the expression of IL-13 and reduced airway inflammation in lung tissues compared with control group.
Conclusion: Our results demonstrated the effectiveness of aerosol inhalation of IL-13 siRNA in preventing airway inflammation in vivo and suggested potential therapeutic applications.
KEYWORDS: IL-13; siRNA; asthma; aerosol inhalation.
Statement of Originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
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Source of funding: This work was supported by the Shanghai Science and Technology Committee (No.10411969100, No.12401900404).
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Copyright © 2015. Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article
Arti Chopra1 DNB OBG, Nimarpreet Kaur2,* MD Physiology, Neeraj Aggarwal3 DNB Surgery, Hatinder Jeetsingh Sethi4 MD Internal Medicine
Affiliation:
1Consultant,Obstetrics and Gynaecology, Asian Multispecialty Hospital, Ludhiana 141002, Punjab, India
2Department of Physiology, SHKM, Govt Medical College, Nalhar, Mewat, Haryana 122107, India
3Consultant Surgery, Asian Multispecialty Hospital, Ludhiana 141002, Punjab, India
4Consultant, Department of internal medicine, Medanta, The Medicity, Gurgaon, Haryana 122001, India
The name of the department(s) and institution(s) to which the work should be attributed:
1.Asian Multispecialty Hospital, Ludhiana 141002, Punjab, India
2.SHKM, Govt Medical College, Nalhar, Mewat, Haryana 122107, India
3. Medanta, The Medicity, Gurgaon, Haryana 122001, India
Address reprint requests to
Dr. Arti Chopra.
Consultant, Asian Multispecialty Hospital, Ludhiana 141002,Pumjab,India or
Dr. Nimarpreet Kaur.
SHKM, Govt Medical College, Nalhar, Mewat, Haryana 122107, India
Article citation:
Chopra A, Kaur N, Aggarwal N, Sethi HJS. Endorette: A minimally invasive,cost effective & outpatient procedure for diagnosis of post menopausal bleeding. J Pharm Biomed Sci. 2015; 05(02):168-173. Available at www.jpbms.info
ABSTRACT: Menopause is defined as the permanent cessation of menses that occur after the cessation of ovarian function, which usually occur after the age of forty. The significance of post menopausal bleeding whatever slight it may be, should not be underestimated. All women with post menopausal bleeding must be examined & investigated. Malignancy must be ruled out.
Aims & Objectives: To study the diagnostic accuracy of Endorette in women with post-menopausal bleeding in endometrial diseases.
Materials & Methods: This study was conducted on 40 patients who presented with post menopausal bleeding. Patients underwent endometrial biopsy using outpatient endometrial sampling device – Endorette.The results were statistically analysed.
Results: In our study a total of forty (40) Post menopausal women were evaluated. Endorette was not possible in three (3) patients out of forty (40) because the endorette cannula could not be advanced into the uterine cavity due to cervical stenosis. The failure rate of the endorette procedure was 7.5% in our study. It could be successfully completed in 92.5% patients. Endorette is carried out as an outpatient procedure requiring no anaesthesia ,cost effective and diagnostic tool.
Conclusion: Outpatient endometrial sampling with endorette should be the first step of investigation in women with post menopausal bleeding to rule out uterine cause.
KEYWORDS: Menopause post menopausal Bleeding; Endometrial biopsy; Endocurette.
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Statement of Originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Source of funding: Department of Biotechnology, Ministry of Science & Technology, and Government of India to R.S
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Copyright © 2015 Chopra A, Kaur N, Aggarwal N, Sethi HJS. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original research article
Quebral, Elgin Paul B.† and Medina, Paul Mark B.*
Affiliation:
†MD-PhD in Molecular Medicine Program, College of Medicine, University of the Philippines Manila, Ermita, Manila, Philippines
*Faculty, Department of Biochemistry and Molecular Biology, College of Medicine, University of the Philippines Manila, Ermita, Manila, Philippines
Author contributions: Both authors contributed equally to this paper.
Address reprint requests to:
Medina, Paul Mark B.
Department of Biochemistry and Molecular Biology, College of Medicine, University of the Philippines Manila, Pedro Gil Street, Ermita, 1000 Manila, Philippines
Office Telephone/Fax: +632 526 0377; +632 526 4197
Article citation:
Quebral, EPB & Medina, PMB. Crude anthocyanin extract (CAE) from Ballatinao black rice hastens regeneration in Dugesia hymanae. J Pharm Biomed Sci. 2015; 05(02):147-153. Available at www.jpbms.info
ABSTRACT: Anthocyanins are a major group of flavonoids that have been examined for various medical and pharmacological applications. However, very few studies have explored the potential of anthocyanins for wound healing and regeneration. We investigated if a crude anthocyanin extract (CAE) from Ballatinao black rice (Oryza sativa L. tropical japonica) can affect regeneration in planarians (Dugesia hymanae). The planarians were transversely cut into two equal parts and were exposed to different concentrations of CAE. Our findings showed that 0.5 μg/ml and 5.0 μg/ml of CAE significantly shortened regeneration time of missing anterior portions of cut planarians by 7.7% (p<0.05). Additionally, 0.5 μg/ml and 5.0 μg/ml of CAE shortened regeneration time of missing posterior portions of cut planarians by 22.4% and 31.3% (p<0.05), respectively. However, 50.0 μg/ml CAE induced lesions in regenerating planarians and was eventually shown to be lethal. Since CAE was able to reduce regeneration time in planarians, CAE may have a therapeutic application in hastening wound healing.
KEYWORDS: Anthocyanin; Ballatinao black rice; Dugesia hymanae; planarian; regeneration; wound healing.
Statement of Originality of Work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
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