DocumentsDate added
Original article
Lokhande Suryabhan L.1,* MD (Biochemistry)., Gadpal Rahul R.2 MD(Biochemistry),Meshram Revatdhamma J.3 MD(Paediatrics), Iyer Chandrashekar M.4 MD(Biochemistry)
Affiliation:
1Assistant Professor, Biochemistry, Jawaharlal Nehru Medical College, Sawangi (M), Wardha; Maharashtra, India
2Assistant Professor, Biochemistry, Government Medical College, Nagpur, Maharashtra, India
3Assistant Professor, Paediatrics, Jawaharlal Nehru Medical College, Sawangi (M), Wardha; Maharashtra, India
4Professor and Head, Biochemistry, Indira Gandhi Govt. Medical College, Nagpur; Maharashtra, India
The name of the department(s) and institution(s) to which the work should be attributed:
1.Jawaharlal Nehru Medical College, Sawangi (M), Wardha; Maharashtra, India
2.Government Medical College, Nagpur, Maharashtra, India
3.Indira Gandhi Govt. Medical College, Nagpur; Maharashtra, India
Address reprint requests to
* Dr. Suryabhan Lahanu Lokhande
Department of Biochemistry, JNMC, Sawangi (M), Wardha,Maharashtra, India-442004
Article citation: Suryabhan LL,Rahul GR,Revatdhamma MJ,Chandrashekar IM. Postprandial Dyslipidemia: Emerging lipid profile for cardiovascular disease risk in Type 2 Diabetes Mellitus subjects: A case control study. J Pharm Biomed Sci. 2015; 05(06):491-498. Available at www.jpbms.info
ABSTRACT:
Background and Objectives: Type 2 Diabetes Mellitus (Type 2 DM), characterized by a relative insulin deficiency or insulin resistance is associated with a cluster of metabolic abnormalities, which includes glucose intolerance, hypertension, a unique dyslipidemia, a procoagulant state, and an increase in macrovascular diseases. The present study was conducted to assess the significance of postprandial dyslipidemia with respect to fasting dyslipidemia, in the pathogenesis of athero-sclerotic changes and possible cardiovascular diseases.
Methods and Statistical Analysis: Fifty clinically diagnosed cases of Type 2 DM ( age group of 34-68 years, duration of diabetes of more than five years), were in¬cluded in the study and 50 age and sex matched healthy subjects were taken as the controls. In both the study groups, we measured postprandial as well as fasting lipid profile, which comprised of serum total Cholesterol (TC), triglycerides (TGs), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and the waist-hip ratio (WHI) as the cardiovascular risk factors. The statistical analysis was done by using the Students unpaired‘t’-test.
Results: The results of present study showed significantly increased levels of postprandial serum total cholesterol, TGs, LDL-C and VLDL-C as compared to those in the fasting state (p<0.001). The serum HDL-C level was significantly lower in the postprandial state as compared to that in the fasting state (p<0.001).
Conclusion: The findings of the study indicated that postprandial lipid profile, as a cardiovascular risk factor, was significantly elevated as compared to lipid profile in fasting state. This signifies that the routine estimation of the postprandial lipid profile, in addition to the fasting lipid parameters is mandatory in the cardiovascular disease risk assessment in Type 2 Diabetes Mellitus subjects.
KEYWORDS: Cardiovascular disease (CVD);Diabetes Mellitus (DM); postprandial blood glucose(PBG); Waist-hip ratio(WHR).
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4.Tushuizen MF, Diamant M, Heine RJ. Postprandial dysmetabolism and cardiovascular disease in Type 2 Diabetes. Postgrad Med J. 2005; 81:1–6.
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17.Tushuizen MF, Diamant M, Heine RJ. Postprandial dysmetabolism and cardiovascular disease in Type 2 Diabetes. Postgrad Med J. 2005; 81:1–6.
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19.Vasilios G. A, Konstantinos T, Asterios K and Dimitri P. M. Dyslipidaemia of Obesity, Metabolic Syndrome and Type 2 Diabetes Mellitus: the Case for Residual Risk Reduction After Statin treatment. The Open Cardiovascular Medicine Journal. 2011; 5: 24-34.
20.Amrane N, Boumediene KM. Effect of Overweight and Obesity on Postprandial Lipaemia among the Subjects with Type 2 Diabetes. J Diabetes Metab. 2012; 3:2:1-5.
21.Kumar V, Madhu SV, Singh G. and Gambhir JK. Post-Prandial Hypertriglyceridemia in Patients with Type 2 Diabetes Mellitus with and without Macrovascular Disease. JAPI. Oct. 2010; Vol. 58;603-607.
22.Byambaa Enkhmaa, Zeynep Ozturk. Postprandial Lipoproteins and Cardiovascular Disease Risk in Diabetes Mellitus. Curr Diab Rep; 2010; 10:61–69.
Statement of Originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Source of funding: None
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Copyright © 2015 Suryabhan LL,Rahul GR,Revatdhamma MJ,Chandrashekar IM. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Ali Mihsen Hussein Al-Yassiri*, Karrar Abdul-ZahraaMahdi
Affiliation:
Assistant lecturer, M.Sc. Oral Medicine, Department of Oral Surgery and Oral Diagnosis, College of Dentistry, University of Babylon, Iraq
The name of the department(s) and institution(s) to which the work should be attributed:
Oral Medicine, Department of Oral Surgery and Oral Diagnosis, College of Dentistry, University of Babylon, Iraq
Address reprint requests to
*Ali Mihsen Hussein Al-Yassiri.
Assistant lecturer, Oral Medicine, Department of Oral Surgery and Oral Diagnosis, College of Dentistry, University of Babylon, Iraq
Article citation: Al-Yassiri Ali MH, Abdul-ZahraaMahdi K. The presence oforofacial manifestations in autistic disorders among group of children samples in Babil and Najaf cities, Iraq. J Pharm Biomed Sci. 2015; 05(06):487-490. Available at www.jpbms.info
ABSTRACT:
Background: Autism is a Kind of disorders that lead to severely failure of ability to communications, interact or adhesion with other child or person and maintain appropriate contact with the outside society or world. Autism is consist of a complex group of neurobiological disorders caused by defects in developments of child's brain; that usually last throughout a lifetime and are classified as autism spectrum disorders (ASDs). These disorders are associated with hared routines and repetitive behaviors and communications. The aim of this study was to find, the type of communication betweenorofacial manifestations and autistic disorders.
Materials and Methods: Children were selected from private specified centers for autistic disorders and special care in Hilla (Babylon) and Najaf cities of Iraq, by periodic visits. One hundred and twenty(120) subjects were incorporated in this study. All these Childs with age ranges (4.5-10.5) years, and were without any other systemic disease. All these patients were previously diagnosed by psychiatrists.
KEYWORDS: Oral manifestations; autistic disorders (AD); Dent alveolar findings.
References:
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19.National Institute of Child Health and Human Development, National Institutes of Health (NIH).Autism Spectrum Disorders. Retrieved from http://www.nichd.nih.gov/health/topics/asd.cfm. 20.Lorena M, Francisco Javier S , Sonia M ,et al : Oral manifestations in a group of adults with autism spectrum disorder , Med Oral Patol Oral Cir Bucal. 2012 May 1;17 (3):e415-9.[Pub Med]
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Statement of Originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Source of funding: None
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Copyright © 2015 Al-Yassiri Ali MH, Abdul-ZahraaMahdi K. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Satwant Kaur1,*, Harjinder Singh2, Kumud Bala Gupta3, Anupa Sood4, Swaran Kaur5
Affiliation:
1Associate Professor, M.M. Medical College & Hospital, Kumarhatti Solon(HP),India
2Assistant Professor, M.M. Medical College & Hospital, Kumarhatti Solon(HP),India
3Professor & Head Department of OBG Department, M.M. Medical College & Hospital, Kumarhatti Solon(HP),India
4Professor, M.M. Medical College & Hospital, Kumarhatti Solon(HP),India
5Professor & Head of Pathology Department in BPSGMC Khanpur-Sonepat(Haryana),India
The name of the department(s) and institution(s) to which the work should be attributed:
1.M.M. Medical College & Hospital, Kumarhatti Solon(HP),India
2.BPSGMC Khanpur-Sonepat (Haryana),India
Address reprint requests to
* Dr Satwant Kaur
Flat no. 228/J Spangle Condos, Dhakoli SAS Nagar Mohali, Punjab: 160104
Article citation: Kaur S, Singh H, Gupta KB, Sood A, Kaur S. Diagnosis of chronic pelvic pain (CPP):USG V/S DL. J Pharm Biomed Sci. 2015; 05(06):516-518. Available at www.jpbms.info
ABSTRACT:
Objective: To find out the correlation between two modalities i.e. USG and DL used in diagnosis of chronic pelvic pain.
Method: One hundred women with chronic pelvic pain attending Gynae OPD were included. They were examined clinically and subjected to USG and DL.
Results: Among the 78 patients with abnormal findings on laparoscopy only 45 had positive USG findings. Though USG had a higher sensitivity for ovarian cysts, laparoscopy was more predictive for other positive findings.
Conclusion: Diagnostic laparoscopy is more sensitive method for diagnosis of chronic pelvic pain.
KEYWORDS: Pelvic Pain; Laparoscopy; Ultrasonography; Chronic pelvic pain; USG; Gynaecological.
Statement of Originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Source of funding: None
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Majority of the information gathered are from media sources which don’t reflect the author’s own opinion.
Copyright © 2015 Kaur S, Singh H, Gupta KB, Sood A, Kaur S. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original Research
Renu Nagar*
Affiliation:
Head of Biochemistry & Point of care in a SEHA Hospital, Abu Dhabi, UAE
The name of the department(s) and institution(s) to which the work should be attributed:
SEHA Hospital, Abu Dhabi, UAE
Address reprint requests to
* Dr Renu Nagar
dr.renunagar@yahoo.com
Article citation: Nagar R. Delivering quicker reports for laboratory tests ordered in emergency departments. J Pharm Biomed Sci. 2015;05(06):505-515. Available at www.jpbms.info
ABSTRACT:
Prolonged turnaround time (TAT) of STAT emergency samples is the single most common cause of complaints about laboratory services all over the world. While the clinicians understandably desire quicker results for quicker clinical decisions affecting clinical outcomes, course and cost of treatment of these very sick patients; pathologists are frustrated by the unrealistic expectations of clinicians, excessive load of unnecessary STAT orders and delays outside laboratories affecting their TAT. This study was planned to find ways to improve TAT of emergency samples with the aim of quicker diagnosis, shorter stay in emergency, improved efficiencies of Emergency department (ED) and Laboratory (Lab), reducing hospital costs and improving patient experience. It was found that causes for delays most often lay outside lab. The remedy lay in correcting certain practices such as leaving drawn samples on bedside before transportation, drawing samples long after logging in Hospital information system, snags in Pnuematic tube system and delayed answering of lab calls in ED informing about critical results. Unnecessary ordering of tests as STAT increased the work load in lab. Other unexpected reasons for prolonged TAT were: non-cancellation of orders for rejected samples but waiting for arrival of a redrawn sample; and placing of future STAT orders for patients admitted from Emergency department. While the former resulted in prolonged Lab time, the latter resulted in prolonged Sample draw time and transport time as the hospital uses Pneumatic tube system for ED samples, but courier system for wards samples.
KEYWORDS: Emergency department (ED); Critical test; STAT tests; Critical result; Turnaround time (TAT); Length of stay; SWOT analysis; Root cause analysis; Fish bone diagram; Process mapping, PDCA; Efficiency of ED; Lab efficiency.
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Statement of Originality of work: The manuscript has been read and approved by the author, the requirements for authorship have been met, and that author believes that the manuscript represents honest and original work.
Source of funding: None
Competing interest / Conflict of interest: The author has no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the author and do not reflect the official policy or position of the Department of Defense.
Copyright © 2015 Nagar R. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Midhun Moopil Mohanan 1, Moksha Nayak 2, Grishma Florence Noronha 3,*,
Jayanth Nambiar 4, Ramya M.K2¥
Affiliation:
1Assistant Dental Surgeon, District Hospital, Palakkad P.O BOX 678001, India
2Principal & Professor,2¥ Senior lecturer, Department of Conservative Dentistry and EndodonticsK.V.G Dental College and Hospital, Kurunjibagh, Sullia: 574327, India
3Senior Lecturer, Department of Conservative Dentistry and Endodontics, A.B Shetty Memorial Institute of Dental Science, Derlakatte- 575018,Mangalore,India
4Senior lecturer, Department of Conservative dentistry and Endodontics, Century Dental College, Poinachi, Kerala, India
The name of the department(s) and institution(s) to which the work should be attributed:
K.V.G. Dental College and Hospital, Kurunjibagh, Sullia, 574327, India
Address reprint requests to
* Dr.Grishma Florence noronha
Senior lecturer, Department of Conservative dentistry and Endodontics, A.B Shetty Memorial Institute of Dental Science, Derlakatte: 575018,Mangalore, India
Article citation: Mohanan MM,Nayak M,Noronha GF,Nambiar J,Ramya MK. Investigation on the mode of action of three desensitizing agents using scanning electron microscopy and spectroscopy: An in-vitro study. J Pharm Biomed Sci. 2015; 05(06):499-504. Available at www.jpbms.info
ABSTRACT:
Aim: This in-vitro study aimed to ascertain the mode of action of three desensitizing agents namely, Arginine-containing, Propolis-containing and Potassium Nitrate-containing dentifrices using scanning electron microscopy and energy-dispersive X-ray spectroscopy. Materials and methods: Ninety dentin slices from non carious human premolar teeth were used for the study. The teeth were randomly divided into three groups (n=30), according to the type of dentifrice applied:- Group I: Arginine-containing paste, Group II: Propolis-containing paste and Group III: Potassium nitrate-containing paste. Each group was divided into two subgroups (n=15) for the assessment by two different techniques: Subgroup A: Scanning electron microscopy examination and Subgroup B: Energy-dispersive X-ray spectroscopy examination. SEM was used to assess the tubule occlusion and the change in the diameter of the dentinal tubules. EDXS was used to characterize the elemental composition of the occlusive material. Analysis of agents, both prior to and after application on dentine discs was performed for comparative purposes. Statistical analysis was done using one-way analysis of variance (ANOVA) and the Bonferroni post hoc test for multiple comparison. Results: The dentin discs treated with arginine-containing paste (93.220% by SEM) showed statistically (p˂001) highest mean percentage of occluded tubules followed by Potassium Nitrate-containing paste (34.777% by SEM) and Propolis-containing paste (13.58 % by SEM). There was a strong evidence (p˂001) that group I (68%) was most effective in reducing the mean tubule diameter, while group II (47%) and III (44%) did not produce a significant reduction. The EDXS studies show that the dentin surface deposit and occluded tubule plugs contain high levels of calcium, phosphorus, fluorine, silica in group I and III treated specimens.
KEYWORDS: Desensitizing agents; Scanning electron microscopy; Confocal laser scanning microscopy; Energy-dispersive X-ray spectroscopy; Dentin hypersensitivity.
Statement of Originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Source of funding: None
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Copyright © 2015 Mohanan MM,Nayak M,Noronha GF,Nambiar J,Ramya MK. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.