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Review article
Divya Jaggi¥*, Anjani Pathak¥, Jaya Dixit¥, Indira Chaturvedi¥, Kopal Goel±
Affiliation:
¥Department of Periodontology, ±Department of Prosthodontics, Faculty of Dental Sciences, King George’s Medical University, Lucknow-226003, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Periodontology, Faculty of Dental Sciences, King George’s Medical University, Lucknow-226003, India
Address reprint requests to
* Dr. Divya Jaggi.
Senior Resident, Department of Periodontology, Faculty of Dental Sciences, King George’s Medical University, Lucknow-226003, India
Article citation: Pathak A, Jaggi D, Dixit J, Chaturvedi I, Yadav K. Pharmacologic agents in periodontics: A review. J Pharm Biomed Sci. 2015;05(07):609-620. Available at www.jpbms.info
ABSTRACT: The fundamental aspect of the treatment is that the clinician should constantly update his knowledge on the drugs being administered during the course of treatment and their interactions. This article focuces on the current pharmacological agents being used in the management of periodontal conditions. All drug sensitivities and allergies should be reviewed prior to incorporating pharmacological agents into a patient’s treatment regimen. Recent advances in technology have led to a constant drive to develop novel strategies for the treatment of periodontal diseases. The future is promising in the areas of vaccines but more research is needed.
KEYWORDS: Pharmacology; Therapeutics; Periodontics.
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Source of funding: None
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Majority of the information gathered are from media sources which don’t reflect the author’s own opinion.
Copyright © 2015 Pathak A, Jaggi D, Dixit J, Chaturvedi I, Yadav K. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
*Shradha Sethi., MDS,† Tarun Sethi., MDS,‡ Kala Bhushan., MDS,** Pinal Kabrawala., MDS,†† Pradeep Kumar., MDS,‡‡ Nitin Sharma., MDS‡‡
Affiliation:
*Department of Periodontology, Rajasthan Dental College and Hospital, Jaipur, India group of Hospitals, Bikaner, Rajasthan, India
†Department of Pedodontics, Rajasthan Dental College and Hospital, Jaipur, India
‡ Department of Periodontology, College of Dental Sciences, Davangere, India
**Department of Pedodontics, Ahmedabad Dental College, Ahmedabad, India
††Department of Periodontology, Rajasthan Dental College and Hospital, Jaipur, India
‡‡Department of Pedodontics, Rajasthan Dental College and Hospital, Jaipur, India
The name of the department(s) and institution(s) to which the work should be attributed:
College of Dental Sciences, Davangere, India
Address reprint requests to
Dr. Shradha Sethi.
Department Of Periodontology,
Rajasthan Dental College and Hospital,Jaipur, India
Article citation:
Sethi S, Sethi T, Bhusan K, Kabrawala P, Kumar P, Sharma N. Assessment of the efficacy of Aloe vera gel in chronic periodontitis patients: A clinical and microbiological study. J Pharm Biomed Sci. 2015; 05(07):598-608. Available at www.jpbms.info
ABSTRACT:
Background & Objectives: In recent years, efforts have been made to test herbal remedies in treating inflammation and infections. Here an attempt is made to assess the clinical benefits of pure Aloe vera gel (98%) used as an adjunct to non surgical periodontal therapy.
Materials and Methods: 10 patients each with at least 3 sites with probing depth 5-7 mm in different quadrants were included. A split mouth design was used and sites in each patient were randomly allocated into experimental sites A (Intrapocket application of Aloe vera gel) & B (gel application along with SRP) and control site C (only SRP). Plaque index, gingival index, gingival bleeding index, probing pocket depth and relative attachment level were assessed at baseline, 3 weeks and 6 weeks. Subgingival plaque sample was collected to assess Streptococci and Porphyromonas gingivalis by anaerobic culture method.
Results: The results showed on intra-group analysis significant reduction (p<0.01) of clinical parameters (PI, GI, GBI, PPD & RAL) and periodontal pathogens in all the treatment groups whereas on inter-group analysis, significant difference was seen between aloe monotherapy and other two groups which had similar outcomes.
Interpretation and Conclusion: In present study treatment with aloe vera gel as an adjunct to SRP showed almost similar results to cases treated with SRP alone without any statistically significant differences. The anti-inflammatory and antimicrobial effects of aloe vera, suggests it as a promising agent to be used for treatment of periodontal diseases. Future studies including larger sample sizes and sustained release formulation of the gel are certainly encouraged to further explore the potential benefits.
KEYWORDS: Aloe vera; chronic periodontitis; scaling and root planing; local drug delivery; periodontopathogens; herbal; anti-inflammatory; antimicrobial.
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Statement of Originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Source of funding: None
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Copyright © 2015 Sethi S,Sethi T,Bhusan K,Kabrawala P,Kumar P,Sharma N. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Case report
Santosh Kumar Sahu*,M.S
Affiliation:
Nilratan Sircar MC & H, Kolkata, India
The name of the department(s) and institution(s) to which the work should be attributed:
Nilratan Sircar MC & H, Kolkata, India
Address reprint requests to
* Dr.Santosh Kumar Sahu.
M.S.Orthopaedics, Nilratan Sircar MC & H, Kolkata, India
Article citation: Sahu SK. Scapular osteochondroma: A rare presentation. J Pharm Biomed Sci. 2015; 05(07):589-593. Available at www.jpbms.info
ABSTRACT: We here with present a case of osteochondroma arising from the from scapula in a 4yrs child presented with huge swelling over the scapular region.Since 1 yr of age the swelling was gradually increasing in size but painless & shoulder movement terminally restricted. The lesion was free from chest wall. There was no h/o- fever, cough, weight loss or any other constitutional symptoms or any neurovascular deficit. There was no h/o trauma.MRI showed a 7.5x6x5 cm, mushroom shaped, pedunculated mass arising from inferior angle & lateral margin of left scapula, lung fields were clear, the lesion was free from chest wall & the surrounding soft tissue density was normal. After thorough investigation, en bloc resection of tumor was done with partial scapulectomy and sent for histopathological examination. The diagnosis of osteochondroma was established on HPE. No residual deficit was found post-operatively. Patient was relieved of the symptoms and is now under follow-up.
KEYWORDS: Osteochondroma of scapula.
Statement of Originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Source of funding: None
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Majority of the information gathered are from media sources which don’t reflect the author’s own opinion.
Copyright © 2015 Sahu SK. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Pedapati Kasturi.* MD, Oruganti Satyanarayana¥. MD., DLO.
Address reprint requests to
* Dr. PEDAPATI. KASTURI, MD
Assistant professor, Department of Microbiology, Rangaraya Medical College, GGH Campus, Kakinada, Andhra Pradesh. PIN: 533001, India
Affiliation:
*Assistant Professor, ¥Associate Professor, Department of Microbiology, Rangaraya Medical College, GGH Campus Kakinada, Andhra Pradesh, India
The name of the department(s) and institution(s) to which the work should be attributed:
Rangaraya Medical College /Government General Hospital, Kakinada, East Godavari District, Andhra Pradesh, India