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Case report
Valgadde Sneha B.* , Chougule Kishor A.†
Affiliation:
*Post-graduate Student, †Professor & Guide, Department of Orthodontics & Dentofacial Orthopedics, T.K.D.C & R.C, New Pargaon, Kolhapur, Maharashtra, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Orthodontics & Dentofacial Orthopedics, T.K.D.C & R.C, New Pargaon, Kolhapur, Maharashtra, India
Address reprint requests to
* Valgadde Sneha B.
Post-graduate Student, Department of Orthodontics & Dentofacial Orthopedics, T.K.D.C & R.C, New Pargaon, Kolhapur, Maharashtra, India
Article citation: Valgadde Sneha B, Chougule Kishor A. Orthodontic management of a skeletal class II malocclusion using twin block appliance and headgear: A progress case report. J Pharm Biomed Sci. 2015; 05(08):662-665. Available at www.jpbms.info
ABSTRACT:
For over a century, the functional appliances have been used for thecorrection of Class II disharmony by mandibular advancement. A case report of 13 year prepubertal female patient with a class II skeletal base withretrognathic mandible is presented. The patient was treated using a twin block appliance with high pull headgear for a period of 12 months following which the patient was shifted to fixed orthodontic mechanotherapy (MBT prescription 0.022” slot). From the present case response it can be concluded that, subjects treated with growth modulation therapy show a great improvement in skeletal and soft tissue balance preventing/ obviating the need for surgical intervention.
KEYWORDS: Skeletal Class II malocclusion; Twin Block; High Pull Headgear.
REFERENCES
1.Paola Cozza, Tiziano Baccetti, Lorenzo Franchi, Laura De Toffol, and James A. McNamara, Jr. Mandibular changes produced by functional appliances in Class II malocclusion: A systematic review Am J Orthod Dentofacial Orthop 2006;129:599.e1-599.e12
2.McNamara JA Jr, Brudon WL. Orthodontics and dentofacial orthopedics. Ann Arbor: Needham Press; 2001. p. 67-80.
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4.Ashok Kumar Jena, Ritu Duggal, and Hari Parkash. Skeletal and dentoalveolar effects of Twin block and bionator appliances in the treatment of Class II malocclusion: A comparative study Am J Orthod Dentofacial Orthop 2006;130:594-602.
5.Daljit S. Gill and Robert T. Lee .Prospective clinical trial comparing the effects of conventional Twin-block and mini-block appliances: Part 1. Hard tissue changes. Am J Orthod Dentofacial Orthop 2005;127:465-72
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Statement of Originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Source of funding: None
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Copyright © 2015 Valgadde Sneha B, Chougule Kishor A.. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article
Choudhry AAfreen (MSc), Guddaiah Rajeshwari (MSc), Prabhu Krishnananda*(MD)
Affiliation:
Department of Biochemistry, Kasturba Medical College Manipal, Manipal University, Manipal 576104, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Biochemistry, Kasturba Medical College Manipal, Manipal University, Manipal 576104, India
Address reprint requests to
* Krishnananda Prabhu
Professor and Head
Department of Biochemistry. Kasturba Medical College Manipal, Manipal University, Manipal– 576104, India
Article citation: AAfreen C, Rajeshwari G, Krishnananda P, HOMA IR/C peptide ratio – A better tool for predicting prognosis of type II diabetes mellitus. J Pharm Biomed Sci. 2015; 05(08):650-654. Available at www.jpbms.info
Insulin resistance is a characteristic feature of type II diabetes which can precede and predict the disease. Homeostatic model assessment (HOMA) is a method for assessing insulin resistance (IR) from basal (fasting) glucose and insulin or C-peptide concentrations. Insulin / c peptide ratio can act as a measure of insulin reserve which in addition indirectly can indicate insulin resistance. Also HOMA-IR / c peptide ratio indicates insulin resistance with respect to endogenous insulin reserve. The aim of this study was to compare the correlations of indices HOMA-IR, Insulin / c peptide ratio and HOMA-IR / c peptide ratio with glycated hemoglobin (HbA1c) and plasma lipid profile in type II diabetic patients.
Methods: Blood glucose, HDL, total cholesterol, triglycerides and LDL were estimated in Cobas 6000 autoanalyser. Glycated hemoglobin was estimated by using HPLC in Variant turbo II. Insulin and C- peptide were estimated by chemiluminescence. Homeostatic model assessment (HOMA-IR) was calculated from basal (fasting) glucose and fasting insulin concentrations.
Results: Strong and significant correlations were observed when HOMA IR/c peptide ratio was compared with HbA1c and plasma lipid profile parameters.
Conclusion: This study indicated that among the indices Insulin / c peptide ratio and HOMA-IR / c peptide ratio
KEYWORDS: Diabetes mellitus; Insulin Resistance; HOMA model; C peptide.
Source of funding: None
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Majority of the information gathered are from media sources which don’t reflect the author’s own opinion.
Copyright © 2015 AAfreen C, Rajeshwari G, Krishnananda P. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article
Jenan Nadhim Sadeq*
Affiliation:
Microbiology and Parasitology Department, College of Veterinary Medicine, University of Al-Qadisiyah, Iraq
The name of the department(s) and institution(s) to which the work should be attributed:
Microbiology and Parasitology Department, College of Veterinary Medicine, University of Al-Qadisiyah, Iraq
Address reprint requests to
* Jenan Nadhim Sadeq.
Microbiology and Parasitology Department, College of Veterinary Medicine, University of Al-Qadisiyah, Iraq
Article citation:
Sadeq JN. Detection important virulence factor (Cytolethal distending toxin gene) in Campylobacter jejuni from chicken by real-time PCR Technique. J Pharm Biomed Sci. 2015; 05(08):632-637. Available at www.jpbms.info
ABSTRACT: Campylobacteriosis is a globally extended distributed zoonotic diseases, cytolethal distending toxin (CDT) is one of the main virulence elements related to Campylobacter jejuni pathogenesis in human and animal species. The contamination of poultry carcasses in slaughterhouses and consequent consumption or handling of raw or undercooked meat is most significant risk factors. In this study we used Real-Time PCR based SYBER Green dye amplification as advance molecular technique in direct detection cytolethal distending toxin gene in genomic DNA that extracted from broiler chicken stool samples, the specific primers was designed in this study by using NCBI-Gen Bank data base and primer 3 plus. Real-time PCR results were show high occurrence of Campylobacter jejuni that carrying virulence factor (Cytolethal distending toxin) in stool samples of broiler chicken. Out of 50 chicken stool samples (41) positive samples at (82%). In conclusion the present study was concluded that shedding of C. jejuni that contains to cytolethal distending toxin (CDT) contributed very important risk factors to public health, use of Real-Time PCR technique is fast and very specific molecular technique.
KEYWORDS: Real-Time PCR technique, Campylobacter jejuni, chicken, cytolethal distending toxin, SYBER Green dye.
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3.Lamb-Rosteski JM, Kalischuk LD, Inglis GD, Buret AG(2008). Epidermal growth factor inhibits Campylobacter jejuni-induced claudin-4 disruption, loss of epithelial barrier function, and Escherichia coli translocation. Infect Immune 76:3390–3398.
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13.Aline Feola de Carvalho, Daniela Martins da Silva, Sergio Santos Azevedo, Rosa Maria Piatti, Margareth Elide Genovez, and Eliana Scarcelli (2013) Detection of CDT toxin genes in Campylobacter spp. strains isolated from broiler carcasses and vegetables in São Paulo, Brazil. Braz J Microbiol. 44(3):693-699.
14.Bang DD, Scheutz F, Gradel KO, Nielsen EM, Pedersen K, Enberg J, Gerner-Smidt P, Handberg K, Madsen M. (2003). Detection of seven virulence and toxin genes of Campylobacter jejuni and Campylobacter coli isolates from different sources and cytolethal distending toxin production suggest potential diversity of pathogenic properties among isolates. Genome Lett.2:62-72.
15.Datta S, Niwa H, Itoh K. 2003.PREVALENCE of of 11 pathogenic genes of Campylobacter jejuni by PCR in strains isolated from humans, poultry meat and broiler and bovine faeces. J. Med. Microbiol. 52: 345-348.
16.Rozynek E, Dzierzanowska-Frangat K, Jozwiak P, Popowski J, Korsak D, Dzierzanowska D.(2005).PREVALENCE of potential virulence markers in Polish Campylobacter jejuni and Campylobacter coli isolates obtained from hospitalized children and from chicken carcasses. J Med Microbiol. 54:615–619.
17.Samosornsuk W, Asakura M, Yoshida E, Taguchi T, Nishimura K, Eampokalap B, Phongsisay V, Chaicumpa W, Yamasaki S.(2007). EVALUATION of a Cytolethal Distending Toxin (cdt) gene-based species-specific Multiplex-PCR assay for the identification of Campylobacter strains isolated from poultry in Thailand. Microbiol Immunol. 51:909–917.
18.Talukder KA, Aslam M, Islam Z, Azmi IJ, Dutta DK, Hossain S, Nur-E-Kamal A, Nair GB, Cravio to A, Sack DA, Endtz HP.(2008).PREVALENCE of virulence genes and cytolethal distending toxin production in C jejuni isolates from diarrheal patients in Bangladesh. J Clin Microbiol.46:1485–1488.
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Statement of Originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Source of funding : None
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research, patents and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Majority of the information gathered are from media sources which don’t reflect the author’s own opinion.
Copyright © 2015 Sadeq JN. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Case report
Mootha Archana1,*, Tobythomas Julie1,€, Malaiappan Sankari1,¥
Affiliation:
1,*Postgraduate Student, 1,€Reader, 1,¥Professor, Department of Periodontics, Saveetha Dental College and Hospitals, Valapanchavadi, India
The name of the department(s) and institution(s) to which the work should be attributed:
Department of Biochemistry, Kasturba Medical College Manipal, Manipal University, Manipal 576104, India
Address reprint requests to
* Archana Mootha.
No 162, Poonamallee High Road,
Department of Periodontics, Saveetha dental college and hospitals, Valapanchavadi, India
Article citation: Mootha A, Tobythomas J, Malaiappan S, Comparison Of Gingival Depigmentation Using Diode Lasers V/s Surgical Stripping: A Report Of Three Cases. J Pharm Biomed Sci. 2015; 05(08):670-678. Available at www.jpbms.info
ABSTRACT: Gingival hyperpigmentation is one of the leading causes of causing unaesthetic appearances of gingival during smiling. This is very common among patients having a gummy smile or a high smile line. Social and psychological problems and esthetic hindrance in smiling prompts these patients to seek dental care and advice. Various surgical corrective measures are available for depigmentation of gingival. Lasers and scalpel are the most popularly used techniques in today’s dental practice. This article reports three cases comparing laser and scalpel depigmentation with a follow up of 1-6 months with depigmentation done on the same sitting. Postoperative clinical results do not show significant difference between the two techniques.
KEYWORDS: Lasers; Gingival depigmentation; Salpel.
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13.Yılmaz S, Algan S, Gursoy H, Noyan U, Kuru BE, Kadir T. Evaluation of the clinical and antimicrobial effects of the Er:YAG laser or topical gaseous ozone as adjuncts to initial periodontal therapy. Photomed Laser Surg 2013;31(6):293-8
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16. Almas K, Sadig W. Surgical treatment of melanin-pigmented gingiva; an esthetic approach. Indian J Dent Res 2002; 13(2):70-3.
17. Atsawasuwan P, Greethong K, Nimmanon V. Treatment of gingival hyperpigmentation for esthetic purposes by Nd:YAG laser: report of 4 cases. J Periodontol 2000; 71(2):315-21.
18. M Bhanu Murthy, Jasjit Kaur, and Rupali Das. Treatment of gingival hyperpigmentation with rotary abrasive, scalpel, and laser techniques: A case series. J Indian Soc Periodontol 2012;16(4):614–619.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Majority of the information gathered are from media sources which don’t reflect the author’s own opinion.
Copyright © 2015 Mootha A,Tobythomas J, Malaiappan S. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.