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Original article
Subrat Chandra1, Sushil Kumar Shukla2*,Dushyant Gaur3 Pooja Gupta4
1Associate Professor, Department of Pathology, Ram Manohar Lohia Institute of Medical Sciences, Vibhuti Khand, Gomti Nagar, Lucknow, India
2Associate Professor, Department of Community Medicine, UP RIMSR, Saifai, Etawah, UP, India
3 Professor & Head, Department of Pathology, HIMS, Dehradun, India
4 Associate Professor, Department of Obs. & Gyn., UP RIMSR, Saifai, Etawah, UP, India
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*Dr. Sushil Kumar Shukla,
Associate Professor, Department of Community Medicine, UP RIMSR, Saifai,Etawah, UP, India
Article citation: Chandra S, Shukla S, Gaur D, Gupta P. A cross-sectional study to identify the proportion of anaplastic carcinoma in thyroid cancer cases reporting to HIMS, Dehradun, India. J Pharm Biomed Sci 2015;05(10):817–821.Available at www.jpbms.info
Abstract
Background Anaplastic carcinoma of the thyroid (ATC) is the most aggressive thyroid gland malignancy. Although ATC accounts for less than 2% of all thyroid cancers, it causes up to 40% of deaths from thyroid cancer. Anaplastic carcinoma consists partly or entirely of undifferentiated cells. This represents 10% of all thyroid carcinomas and this is the most aggressive neoplasm of this gland.
Objective To estimate the proportion of anaplastic carcinoma and its subtypes. Methods and Results We studied 150 cases out of which 15 were reported as thyroid malignancy. Anaplastic carcinomas are reported here in four cases of middle age 5th and 6th decay of their life, two male and two female 1:1 with history suggestive of hyperthyroidism in three cases and euthyroid in one case. The tumours were of variable size and showed large pleomorphic cells in clusters as well as in an isolated form. The femaleto- male ratio was approximately 3:1. Peak incidence occurs during the third to fourth decades of life. The age range of affected patients reportedly is 15–70 years.
Conclusion ATC is a very uncommon malignancy but in our study we found four cases and we confirmed it by histopathological examination.
KEYWORDS anaplastic carcinoma, thyroid cancer, neoplastic lesions, hyperthyroidism, euthyroid
Statement of originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Source of funding: None.
Competing interest / Conflict of interest: The author(s) have no competing interests for financial support, publication of this research,patents, and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Case Report
Ambarisha Bhandiwad1, Surakshith L. Gowda2*
1Professor and Head, Department of OBG,JSS Medical College, JSS University,Mysore, Karnataka, India
2Junior Resident, Department of OBG, JSS Medical College, JSS University, Mysore,Karnataka, India
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*Dr. Surakshith L. Gowda,
No. 140/4, 2nd Cross, Shankarmutt road, Fort Mohalla,Mysore 570004, Karnataka, India
Article citation: Bhandiwad A, Gowda SL.Hepatitis E in pregnancy: a case report.J Pharm Biomed Sci 2015;05(10):797–798.Available at www.jpbms.info
ABSTRACT Viral hepatitis is one of the most common infectious diseases in developing countries. Hepatitis E in particular has a wide geographical variation and it either occur
as epidemics or seen as sporadic cases. Mainly when pregnant women are affected with Hepatitis E, the disease will be more severe if the women is in second or third trimester,
particularly in third trimester, where chances of fulminant hepatic failure is more with high mortality rates. Here we are presenting a case of acute viral hepatitis complicating pregnancy
where the women goes into spontaneous labour and almost ends in postpartum hemorrhage. Due to timely intervention by transfusing blood components the possible
harm was prevented. Each patient can behave in different way so the plan of management should be tailor made to each patient.
KEYWORDS Viral hepatitis, hepatitis E, pregnancy, fulminant hepatic failure, postpartum haemorrhage, component therapy
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Source of funding: None.
Competing interest / Conflict of interest:
The author(s) have no competing interests for financial support, publication of this research, patents, and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.
Original article
Sudipta Kar*
Sr. Lecturer, Department of Paedodontics & Preventive Dentistry, Guru Nanak Institute of Dental Sciences & Research, Kolkata 114, West Bengal, India
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*Sudipta Kar,
21F, Charakdanga Road, Uttarpara, Hooghly 712258,
West Bengal, India
Article citation: Sudipta K. A COMPARATIVE PREALENCE STUDY OF ORAL HABIT STATUS AMONG IVF AND SPONTANEOUSLY CONCEIVED CHILDREN OF WEST BENGAL. J Pharm Biomed Sci 2015;05(10):782–786. Available at www.jpbms.info
Objective In-Vitro fertilization is one of the modern treatments modality of infertility. Deleterious oral habits are the common problem often found by the dental surgeons during routine examination. Oral habits are repetitive behaviour in the oral cavity that exhibited in different ways like thumb sucking, lip sucking, nail biting, mouth breathing, tongue thrusting, handkerchief biting, etc. Development of oral habits may cause dentoalveolar and/or skeletal deformation in children and ultimately form, function, and aesthetics of orofacial region may be compromised.
Results The results showed that the PREVALENCE of oral habits in IVF children was 39.3%. Thumb sucking was relatively more common habit and seen in only 16.66% of IVF children.
Nail biting was found in 11.33%, handkerchief biting in 3.33%, and the result was significant at p < 0.05. Tongue thrusting (6%) and mouth breathing (2%) cases was relatively less common of IVF children and the result is not significant at p < 0.05 level. Presence of handkerchief biting is a unique finding of the present study.
Conclusion The deleterious oral habits restrict proper growth and development of orofacial structure of IVF children. So these kinds of habits should be interrupted and treated as early as possible.
KEYWORDS IVF children, oral habits, thumb sucking, mouth breathing, PREVALENCE, tongue thrusting, handkerchief biting
Key Messages: IVF children are more oral habit prone.
Statement of originality of work: The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and that each author believes that the manuscript represents honest and original work.
Source of funding: None.
Competing interest / Conflict of interest:
The author(s) have no competing interests for financial support, publication of this research, patents, and royalties through this collaborative research. All authors were equally involved in discussed research work. There is no financial conflict with the subject matter discussed in the manuscript.
Disclaimer: Any views expressed in this paper are those of the authors and do not reflect the official policy or position of the Department of Defense.